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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of protein secretion
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Accession:GO:0050709 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
Synonyms:exact_synonym: down regulation of protein secretion;   downregulation of protein secretion
 narrow_synonym: inhibition of protein secretion



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negative regulation of protein secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in ISO (PMID:28341552) RGD PMID:28341552 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Anxa1 annexin A1 IMP RGD PMID:8559285 RGD:2306956 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:27044754)
GO_REF:0000107
RGD
Ensembl
PMID:27044754 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cyp51 cytochrome P450, family 51 involved_in ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Dph3 diphthamide biosynthesis 3 involved_in ISO (PMID:14980502) RGD PMID:14980502 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (PMID:16839358) RGD PMID:16839358 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO (PMID:16839358) RGD PMID:16839358 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA
ISO
GO_REF:0000107
(PMID:16839358)
Ensembl
RGD
PMID:16839358 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO (PMID:22064321) RGD PMID:22064321 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Frmd4a FERM domain containing 4A involved_in ISO (MGI:5924899|PMID:27044754) RGD PMID:27044754 MGI:5924899 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in ISO (MGI:6270905|PMID:20876579) RGD PMID:20876579 MGI:6270905 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Il12a interleukin 12A acts_upstream_of_or_within ISO UniProtKB:P29460 (PMID:30106099) RGD PMID:30106099 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B acts_upstream_of_or_within ISO UniProtKB:P29459 (PMID:30106099) RGD PMID:30106099 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:14739855) RGD PMID:14739855 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Mir30c1 microRNA 30c-1 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir30c2 microRNA 30c-2 acts_upstream_of ISO (PMID:23749231) RGD PMID:23749231 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Mir93 microRNA 93 acts_upstream_of ISO (PMID:26986724) RGD PMID:26986724 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO (MGI:4455113|PMID:20065295) RGD PMID:20065295 MGI:4455113 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21439629)
UniProt
RGD
PMID:21439629 GO_REF:0000024 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 involved_in ISO (MGI:5009752|PMID:21439629) RGD PMID:21439629 MGI:5009752 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO
IEA
ISS
(PMID:19074433)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19074433 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G Sergef secretion regulating guanine nucleotide exchange factor involved_in ISO
IBA
(PMID:12459492)
PMID:21873635
RGD PMID:12459492 PMID:21873635 RGD:13792537 NCBI chr 1:96,949,660...97,152,529
Ensembl chr 1:96,949,661...97,152,496
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 IMP RGD PMID:10625663 RGD:1299445 NCBI chr10:82,511,101...82,568,706
Ensembl chr10:82,504,393...82,571,040
JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:4457852 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
negative regulation of adiponectin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta involved_in ISO (MGI:3828398|PMID:16865359) RGD PMID:16865359 MGI:3828398 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 involved_in ISO
IEA
(PMID:24040321)
GO_REF:0000107
RGD
Ensembl
PMID:24040321 GO_REF:0000107 NCBI chr16:64,886,902...64,917,491
Ensembl chr16:64,884,676...64,917,491
JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 involved_in ISO (PMID:24040321) RGD PMID:24040321 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:24040321) RGD PMID:24040321 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
negative regulation of BMP secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir106a microRNA 106a acts_upstream_of ISO (PMID:23399447) RGD PMID:23399447 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661
JBrowse link
G Mir140 microRNA 140 acts_upstream_of ISO (PMID:24928442) RGD PMID:24928442 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir17 microRNA 17 acts_upstream_of ISO (PMID:23399447) RGD PMID:23399447 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir210 microRNA 210 acts_upstream_of ISO (PMID:29944867) RGD PMID:29944867 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir214 microRNA 214 acts_upstream_of ISO (PMID:30703347) RGD PMID:30703347 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G Mir93 microRNA 93 acts_upstream_of ISO (PMID:28797104) RGD PMID:28797104 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mir98 microRNA 98 acts_upstream_of ISO (PMID:27860183) RGD PMID:27860183 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
negative regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 involved_in IDA
ISO
MGI:2388392 (MGI:3831492|PMID:16924481), (MGI:7333031|PMID:25771886) RGD PMID:16924481 PMID:25771886 PMID:15163199 MGI:3831492 MGI:7333031, RGD:1598646 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Acvr1c activin A receptor type 1C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3512292 (MGI:3796011|PMID:18480258)
Ensembl
RGD
PMID:18480258 GO_REF:0000107 MGI:3796011 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10952463)
(MGI:3772319|PMID:17992256), (MGI:7343840|PMID:1898674)
RGD PMID:1898674 PMID:10952463 PMID:17992256 MGI:3772319 MGI:7343840 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Bmp8a bone morphogenetic protein 8a involved_in ISO (PMID:22579288) RGD PMID:22579288 NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
JBrowse link
G Ccn3 cellular communication network factor 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5517610|PMID:23705021)
UniProt
RGD
PMID:23705021 GO_REF:0000024 MGI:5517610 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Chga chromogranin A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18216393 RGD:2311570 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO MGI:2179844 (MGI:3772319|PMID:17992256) RGD PMID:17992256 MGI:3772319 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D involved_in ISS
ISO
GO_REF:0000024
(PMID:12160727)
UniProt
RGD
PMID:12160727 GO_REF:0000024 NCBI chr15:16,538,881...16,574,468
Ensembl chr15:16,539,489...16,573,034
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (MGI:6442875|PMID:30997682) RGD PMID:30997682 MGI:6442875 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO MGI:2685324 (MGI:5704028|PMID:25581519), (MGI:5780510|PMID:26075576) RGD PMID:25581519 PMID:26075576 MGI:5704028 MGI:5780510 NCBI chr 1:86,071,860...86,075,049
Ensembl chr 1:86,072,184...86,075,033
JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISO MGI:2441731|MGI:3829251 (MGI:5704028|PMID:25581519), (MGI:5909396|PMID:26091414), (MGI:6450661|PMID:32073900) RGD PMID:25581519 PMID:26091414 PMID:32073900 MGI:5704028 MGI:5909396 MGI:6450661 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Foxo1 forkhead box O1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971)
UniProt
RGD
PMID:12219087 PMID:27457971 GO_REF:0000024 MGI:2388494 MGI:6101624 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide acts_upstream_of_or_within ISO
IDA
MGI:3709886 (MGI:3709118|PMID:17130496) RGD PMID:17130496 PMID:17130496 MGI:3709118, RGD:8553721 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor acts_upstream_of_or_within IDA PMID:17130496 MGI PMID:17130496 RGD:8553721 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gnao1 G protein subunit alpha o1 involved_in ISO MGI:4889047 (MGI:4887503|PMID:21220323)
MGI:4941848 (MGI:4941424|PMID:20622165)
RGD PMID:20622165 PMID:21220323 MGI:4887503 MGI:4941424 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnaz G protein subunit alpha z involved_in ISO MGI:3575007 (MGI:3775331|PMID:18096703) RGD PMID:18096703 MGI:3775331 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IMP RGD PMID:17491019 RGD:2302227 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:22772764 RGD:9590127 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:1857203 (MGI:3796011|PMID:18480258)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18480258 GO_REF:0000024 GO_REF:0000107 MGI:3796011 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Irs1 insulin receptor substrate 1 involved_in IMP
IEA
ISO
PMID:12435589
GO_REF:0000107
(PMID:15572028)
Ensembl
RGD
PMID:15572028 PMID:12435589 GO_REF:0000107, RGD:729325 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3770494|PMID:17767909)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17767909 GO_REF:0000024 GO_REF:0000107 MGI:3770494 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 involved_in ISO (PMID:8923010)
MGI:2178821 (MGI:3831492|PMID:16924481), (MGI:6780326|PMID:33196462)
RGD PMID:8923010 PMID:16924481 PMID:33196462 MGI:3831492 MGI:6780326 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IDA RGD PMID:16133261 RGD:1581603 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Midn midnolin acts_upstream_of_or_within IDA PMID:24187134 MGI PMID:24187134 RGD:8655525 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
JBrowse link
G Mtnr1a melatonin receptor 1A IMP RGD PMID:22288848 RGD:9686057 NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919
JBrowse link
G Mtnr1b melatonin receptor 1B IMP RGD PMID:18363673 RGD:9588673 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:17130471 RGD:1642149 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Npff neuropeptide FF-amide peptide precursor IDA RGD PMID:1704109 RGD:2316580 NCBI chr 7:133,654,530...133,655,319 JBrowse link
G Pde8b phosphodiesterase 8B IMP RGD PMID:17991719 RGD:2312519 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
JBrowse link
G Pfkl phosphofructokinase, liver type acts_upstream_of_or_within ISO (MGI:1096000|PMID:9287040) RGD PMID:9287040 MGI:1096000 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in IMP PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:24187134)
ParkinsonsUK-UCL
RGD
PMID:24187134 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 involved_in IMP PMID:16099819 BHF-UCL PMID:16099819 RGD:8554418 NCBI chr12:33,337,182...33,357,468 JBrowse link
G Ptger3 prostaglandin E receptor 3 IDA RGD PMID:10531320 RGD:10043332 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:3522021 (MGI:3513751|PMID:15520383) RGD PMID:15520383 MGI:3513751 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20942606)
UniProt
Ensembl
RGD
PMID:20942606 GO_REF:0000024 GO_REF:0000107 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (MGI:5619445|PMID:23092880) RGD PMID:23092880 MGI:5619445 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17994217)
Ensembl
RGD
PMID:17994217 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sirt4 sirtuin 4 involved_in
acts_upstream_of_or_within
ISO (PMID:17715127)
MGI:3769237|MGI:95753 (MGI:3769241|PMID:16959573)
RGD PMID:16959573 PMID:17715127 MGI:3769241 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within ISO MGI:2177773 (MGI:3770077|PMID:16890542) RGD PMID:16890542 MGI:3770077 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stxbp5l syntaxin binding protein 5L acts_upstream_of_or_within ISO (MGI:5296997|PMID:21998599) RGD PMID:21998599 MGI:5296997 NCBI chr11:63,334,667...63,654,270
Ensembl chr11:63,334,667...63,657,014
JBrowse link
G Sytl4 synaptotagmin-like 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3770077|PMID:16890542)
Ensembl
RGD
PMID:16890542 GO_REF:0000107 MGI:3770077 NCBI chr  X:97,135,500...97,185,867
Ensembl chr  X:97,135,500...97,185,854
JBrowse link
G Uts2 urotensin 2 IMP RGD PMID:17931748 RGD:2306798 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
G Vsnl1 visinin-like 1 acts_upstream_of_or_within ISO (MGI:3694336|PMID:16731532) RGD PMID:16731532 MGI:3694336 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
JBrowse link
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in ISO
IMP
(PMID:19965390) RGD PMID:19965390 PMID:19965390 RGD:2316628 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17360501 RGD:2306172 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Eny2 ENY2, transcription and export complex 2 subunit IMP RGD PMID:22649445 RGD:9590329 NCBI chr 7:75,581,215...75,605,903
Ensembl chr 7:75,581,240...75,605,897
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B acts_upstream_of_or_within ISO MGI:2182644 (MGI:4421103|PMID:19805579) RGD PMID:19805579 MGI:4421103 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:20610886 RGD:5508687 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Jagn1 jagunal homolog 1 IMP RGD PMID:26882284 RGD:11520872 NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288
JBrowse link
G Klf7 KLF transcription factor 7 involved_in ISO (PMID:16339272) RGD PMID:16339272 NCBI chr 9:65,437,535...65,484,720
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G LOC120094803 Kruppel like factor 7 involved_in ISO (PMID:16339272) RGD PMID:16339272 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr 5:75,142,157...75,564,845 JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 IMP RGD PMID:19690174 RGD:7495848 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 acts_upstream_of_or_within ISO (MGI:5467193|PMID:22587331) RGD PMID:22587331 MGI:5467193 NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316
JBrowse link
G Pde1c phosphodiesterase 1C IMP RGD PMID:18706893 RGD:2302857 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219
JBrowse link
G Pde3b phosphodiesterase 3B IMP RGD PMID:18706893 RGD:2302857 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
JBrowse link
G Pde4c phosphodiesterase 4C IMP RGD PMID:18706893 RGD:2302857 NCBI chr16:18,690,727...18,711,555
Ensembl chr16:18,691,700...18,710,640
JBrowse link
G Pde8b phosphodiesterase 8B IMP RGD PMID:18706893 RGD:2302857 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5294526|PMID:21099329)
UniProt
Ensembl
RGD
PMID:21099329 GO_REF:0000024 GO_REF:0000107 MGI:5294526 NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 IMP RGD PMID:20167843 RGD:12904047 NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427
JBrowse link
G Tbc1d1 TBC1 domain family member 1 IMP RGD PMID:28177704 RGD:150521607 NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
JBrowse link
G Ucp2 uncoupling protein 2 IMP RGD PMID:21172424 RGD:7204422 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
negative regulation of matrix metallopeptidase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd200 Cd200 molecule involved_in ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312 GO_REF:0000107 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 IMP RGD PMID:22105553 RGD:11522738 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:21329689) RGD PMID:21329689 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:28358369) RGD PMID:28358369 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Mir19a microRNA 19a acts_upstream_of ISO UniProtKB:O60603 (PMID:22105995), (PMID:28078022) RGD PMID:22105995 PMID:28078022 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of ISO (PMID:22105995) RGD PMID:22105995 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir19b2 microRNA 19b-2 acts_upstream_of ISO (PMID:22105995) RGD PMID:22105995 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167
JBrowse link
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Madd MAP-kinase activating death domain IMP RGD PMID:23702376 RGD:9588639 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
negative regulation of prolactin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 IMP RGD PMID:15256781 RGD:10053690 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
negative regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2r coagulation factor II (thrombin) receptor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5315674|PMID:21859963)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21859963 GO_REF:0000024 GO_REF:0000107 MGI:5315674 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
negative regulation of secretion of lysosomal enzymes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2651471 (MGI:3697540|PMID:16979922) RGD PMID:16979922 MGI:3697540 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3822255|PMID:18806227)
Ensembl
RGD
PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
negative regulation of Wnt protein secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprm1 opioid receptor, mu 1 involved_in ISO
ISS
(PMID:20214800)
GO_REF:0000024
RGD
UniProt
PMID:20214800 GO_REF:0000024 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    negative regulation of biological process 5819
      negative regulation of transport 600
        negative regulation of protein transport 173
          negative regulation of protein secretion 107
            negative regulation of BMP secretion + 7
            negative regulation of Wnt protein secretion 1
            negative regulation of adiponectin secretion 4
            negative regulation of insulin secretion + 62
            negative regulation of matrix metallopeptidase secretion 7
            negative regulation of pancreatic amylase secretion 1
            negative regulation of pancreatic trypsinogen secretion 0
            negative regulation of prolactin secretion 1
            negative regulation of renin secretion into blood stream 1
            negative regulation of secretion of lysosomal enzymes 2
Path 2
Term Annotations click to browse term
  biological_process 19874
    localization 5646
      macromolecule localization 3105
        cellular macromolecule localization 2629
          protein localization 2620
            establishment of protein localization 1740
              protein transport 1614
                protein secretion 457
                  regulation of protein secretion 358
                    negative regulation of protein secretion 107
                      negative regulation of BMP secretion + 7
                      negative regulation of Wnt protein secretion 1
                      negative regulation of adiponectin secretion 4
                      negative regulation of insulin secretion + 62
                      negative regulation of matrix metallopeptidase secretion 7
                      negative regulation of pancreatic amylase secretion 1
                      negative regulation of pancreatic trypsinogen secretion 0
                      negative regulation of prolactin secretion 1
                      negative regulation of renin secretion into blood stream 1
                      negative regulation of secretion of lysosomal enzymes 2
paths to the root