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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of defense response to virus
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Accession:GO:0050688 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
Synonyms:exact_synonym: regulation of antiviral response



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regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 acts_upstream_of_or_within ISO MGI:3809768 (MGI:54738|PMID:293683) RGD PMID:293683 MGI:54738 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922
JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:1350360 (MGI:4830018|PMID:20709950) RGD PMID:20709950 MGI:4830018 NCBI chr 1:95,719,171...95,724,662
Ensembl chr 1:95,719,190...95,724,648
JBrowse link
G Elmod2 ELMO domain containing 2 involved_in ISO (PMID:17452337) RGD PMID:17452337 NCBI chr19:24,786,166...24,805,626
Ensembl chr19:24,786,241...24,805,130
JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (MGI:76803|PMID:7566153) RGD PMID:7566153 MGI:76803 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO (MGI:4839450|PMID:16306937) RGD PMID:16306937 MGI:4839450 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:88330 (MGI:4830018|PMID:20709950) RGD PMID:20709950 MGI:4830018 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2158363 (MGI:5902878|PMID:28246125)
(PMID:28246125)
RGD PMID:28246125 MGI:5902878 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
negative regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO (PMID:19666601)
(MGI:3722754|PMID:17709747)
RGD PMID:17709747 PMID:19666601 MGI:3722754 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA
(PMID:19666601)
(MGI:3722754|PMID:17709747)
GO_REF:0000107
RGD
Ensembl
PMID:17709747 PMID:19666601 GO_REF:0000107 MGI:3722754 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G C1qbp complement C1q binding protein involved_in ISO
ISS
IEA
(PMID:19164550)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Foxp3 forkhead box P3 IMP RGD PMID:17878294 RGD:2325989 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Htra1 HtrA serine peptidase 1 IMP RGD PMID:15333144 RGD:2311622 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in ISO (PMID:29802199) RGD PMID:29802199 NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(MGI:6810721|PMID:34467632)
(PMID:34467632), (PMID:36221902)
UniProt
RGD
PMID:34467632 PMID:36221902 GO_REF:0000024 MGI:6810721 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:19881509)
(MGI:4436832|PMID:19881509)
RGD PMID:19881509 MGI:4436832 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543
JBrowse link
G Mir26b microRNA 26b involved_in ISO (PMID:26222045) RGD PMID:26222045 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:19881509) RGD PMID:19881509 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISO
IEA
ISS
(PMID:22750291)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22750291 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:25254379) RGD PMID:25254379 NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:22079989)
(MGI:5306204|PMID:22079989)
GO_REF:0000107
RGD
Ensembl
PMID:22079989 GO_REF:0000107 MGI:5306204 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977
JBrowse link
G Trim38 tripartite motif containing 38 acts_upstream_of_or_within ISO (MGI:5441682|PMID:22539786) RGD PMID:22539786 MGI:5441682 NCBI chr17:41,351,857...41,365,021 JBrowse link
negative regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:3828224|PMID:18851954) RGD PMID:18851954 MGI:3828224 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II involved_in ISO (PMID:36159777) RGD PMID:36159777 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
ISS
(PMID:11641396)
GO_REF:0000024
RGD
UniProt
PMID:11641396 GO_REF:0000024 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link
positive regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO (MGI:3839029|PMID:19158675) RGD PMID:19158675 MGI:3839029 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IBA
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437)
GO_REF:0000033
(MGI:5487472|PMID:23258413), (MGI:5505711|PMID:23929945), (MGI:5908326|PMID:24077100)
RGD
GO_Central
PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 GO_REF:0000033 MGI:5487472 MGI:5505711 MGI:5908326 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:20091349) RGD PMID:20091349 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO UniProtKB:P42224|UniProtKB:Q8IXQ6 (PMID:26479788) RGD PMID:26479788 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538
JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:5700304|PMID:16601681)
UniProt
RGD
PMID:16601681 GO_REF:0000024 MGI:5700304 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:22483866) RGD PMID:22483866 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20628368)
UniProt
RGD
PMID:20628368 GO_REF:0000024 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:12421946)
(MGI:3027369|PMID:14688363)
RGD PMID:12421946 PMID:14688363 MGI:3027369 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:12421946) RGD PMID:12421946 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:12421946)
(MGI:3027369|PMID:14688363)
RGD PMID:12421946 PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il23r interleukin 23 receptor involved_in ISO (PMID:12421946) RGD PMID:12421946 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
JBrowse link
G Il27 interleukin 27 acts_upstream_of_or_within ISO MGI:107656 (MGI:5644636|PMID:25268627) RGD PMID:25268627 MGI:5644636 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il4 interleukin 4 IDA RGD PMID:9721086 RGD:8142392 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:16127453), (PMID:19609254), (PMID:20628368)
MGI:3654145 (MGI:3807296|PMID:18780793)
GO_REF:0000024
RGD
UniProt
PMID:16127453 PMID:18780793 PMID:19609254 PMID:20628368 GO_REF:0000024 MGI:3807296 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO UniProtKB:P42224|UniProtKB:Q8TDB6 (PMID:26479788) RGD PMID:26479788 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:16873256)
(PMID:16873257)
RGD PMID:16873256 PMID:16873257 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:26046437)
UniProt
RGD
PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:3839029|PMID:19158675) RGD PMID:19158675 MGI:3839029 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:19609254) RGD PMID:19609254 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Selenok selenoprotein K involved_in ISO (MGI:4939970|PMID:21220695) RGD PMID:21220695 MGI:4939970 NCBI chr16:5,152,066...5,160,648
Ensembl chr16:5,152,066...5,159,188
JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192
JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6 (PMID:26479788) RGD PMID:26479788 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA
(PMID:18818105)
GO_REF:0000107
RGD
Ensembl
PMID:18818105 GO_REF:0000107 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20628368)
Ensembl
UniProt
RGD
PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO (PMID:23066157) RGD PMID:23066157 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (MGI:5775261|PMID:25848864) RGD PMID:25848864 MGI:5775261 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253
JBrowse link
G Trim44 tripartite motif-containing 44 involved_in ISO
IEA
(PMID:23460740)
GO_REF:0000107
RGD
Ensembl
PMID:23460740 GO_REF:0000107 NCBI chr 3:88,593,619...88,729,085
Ensembl chr 3:88,592,719...88,729,188
JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO (PMID:23355615) RGD PMID:23355615 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO (PMID:25299331)
(MGI:6392967|PMID:25299331)
RGD PMID:25299331 MGI:6392967 NCBI chr19:33,350,533...33,375,717
Ensembl chr19:33,350,533...33,375,616
JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 involved_in ISO (PMID:29429998) RGD PMID:29429998 NCBI chr 1:29,296,334...29,327,227
Ensembl chr 1:29,296,334...29,326,898
JBrowse link
regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx9 DExH-box helicase 9 involved_in ISO (MGI:5908739|PMID:28636595) RGD PMID:28636595 MGI:5908739 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Ifna1 interferon, alpha 1 involved_in ISO (MGI:5583923|PMID:24784232) RGD PMID:24784232 MGI:5583923 NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925
JBrowse link
G Ifng interferon gamma involved_in ISO (MGI:5583923|PMID:24784232) RGD PMID:24784232 MGI:5583923 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifnlr1 interferon, lambda receptor 1 involved_in ISO (PMID:12469119) RGD PMID:12469119 NCBI chr 5:147,919,547...147,942,328
Ensembl chr 5:147,919,908...147,942,332
JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2136897 (MGI:1354083|PMID:10704459)
GO_REF:0000107
RGD
Ensembl
PMID:10704459 GO_REF:0000107 MGI:1354083 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA
(MGI:5583923|PMID:24784232)
GO_REF:0000107
RGD
Ensembl
PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO
GO_REF:0000107
(MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Rnf216 ring finger protein 216 involved_in ISO (PMID:19893624) RGD PMID:19893624 NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304
JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 IDA RGD PMID:12215647 RGD:634516 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    response to stimulus 10881
      response to biotic stimulus 1880
        regulation of response to biotic stimulus 556
          regulation of defense response to virus 68
            negative regulation of defense response to virus + 19
            regulation of defense response to virus by host + 46
Path 2
Term Annotations click to browse term
  biological_process 20328
    response to stimulus 10881
      response to external stimulus 3277
        response to external biotic stimulus 1838
          response to other organism 1834
            defense response to other organism 1292
              defense response to symbiont 1149
                defense response to virus 288
                  regulation of defense response to virus 68
                    negative regulation of defense response to virus + 19
                    regulation of defense response to virus by host + 46
paths to the root