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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of defense response to virus
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Accession:GO:0050688 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
Synonyms:exact_synonym: regulation of antiviral response


show annotations for term's descendants           Sort by:
regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 acts_upstream_of_or_within ISO MGI:3809768 (PMID:293683) RGD PMID:293683 NCBI chr 7:113,314,196...113,333,306
Ensembl chr 7:111,433,764...111,452,922 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:1350360 (PMID:20709950) RGD PMID:20709950 NCBI chr 1:104,855,622...104,861,111
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Elmod2 ELMO domain containing 2 involved_in ISO (PMID:17452337) RGD PMID:17452337 NCBI chr19:41,690,713...41,710,194
Ensembl chr19:24,786,241...24,805,130
Ensembl chr18:24,786,241...24,805,130 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:7566153) RGD PMID:7566153 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO
IEA		 (PMID:16306937)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:16306937 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:88330 (PMID:20709950) RGD PMID:20709950 NCBI chr 1:207,619,566...207,633,885
Ensembl chr 1:198,190,164...198,204,445 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO
IEA		 (PMID:28246125)
GO_REF:0000107
MGI:2158363 (PMID:28246125)		 RGD
Ensembl		 PMID:28246125 GO_REF:0000107 NCBI chr 5:139,912,395...139,945,532
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
negative regulation of defense response to virus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg12 autophagy related 12 involved_in ISO (PMID:19666601)
(PMID:17709747)		 RGD PMID:17709747 PMID:19666601 NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA		 (PMID:19666601)
(PMID:17709747)
GO_REF:0000107		 RGD
Ensembl		 PMID:17709747 PMID:19666601 GO_REF:0000107 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G C1qbp complement C1q binding protein involved_in ISO
ISS
IEA		 (PMID:19164550)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO
IEA		 MGI:3582343 (PMID:29341118)
GO_REF:0000107		 RGD
Ensembl		 PMID:29341118 GO_REF:0000107 NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Foxp3 forkhead box P3 IMP RGD PMID:17878294 RGD:2325989 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Htra1 HtrA serine peptidase 1 IMP RGD PMID:15333144 RGD:2311622 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains involved_in ISO
IEA		 (PMID:29802199)
GO_REF:0000107		 RGD
Ensembl		 PMID:29802199 GO_REF:0000107 NCBI chr20:5,811,721...5,878,082
Ensembl chr20:5,809,936...5,876,012 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:34467632)
(PMID:34467632), (PMID:36221902)		 UniProt
Ensembl
RGD		 PMID:34467632 PMID:36221902 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:19881509)
GO_REF:0000107		 RGD
Ensembl		 PMID:19881509 GO_REF:0000107 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Mir26b microRNA 26b involved_in ISO (PMID:26222045) RGD PMID:26222045 NCBI chr 9:83,425,709...83,425,793
Ensembl chr 9:75,976,596...75,976,680 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:19881509) RGD PMID:19881509 NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B involved_in ISO
IEA
ISS		 (PMID:22750291)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22750291 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:15,399,559...15,460,301
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:25254379) RGD PMID:25254379 NCBI chr 8:53,351,388...53,353,586
Ensembl chr 8:44,454,292...44,457,331 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:22079989)
GO_REF:0000107		 RGD
Ensembl		 PMID:22079989 GO_REF:0000107 NCBI chr 9:99,521,176...99,557,966
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
G Trim38 tripartite motif containing 38 acts_upstream_of_or_within ISO (PMID:22539786) RGD PMID:22539786 NCBI chr17:41,774,419...41,787,709 JBrowse link
negative regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:23399697)
GO_REF:0000107		 RGD
Ensembl		 PMID:23399697 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II involved_in ISO
IEA		 (PMID:36159777)
GO_REF:0000107		 RGD
Ensembl		 PMID:36159777 GO_REF:0000107 NCBI chr 1:255,712,797...255,838,285
Ensembl chr 1:245,772,277...245,897,913 		JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
IEA
ISS		 (PMID:11641396)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11641396 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:135,527,710...135,532,826
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
positive regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO
IEA		 (PMID:19158675)
GO_REF:0000107		 RGD
Ensembl		 PMID:19158675 GO_REF:0000107 NCBI chr13:88,397,516...88,439,325
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA
IBA		 (PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:20091349) RGD PMID:20091349 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO
IEA		 UniProtKB:P42224|UniProtKB:Q8IXQ6 (PMID:26479788)
GO_REF:0000107		 RGD
Ensembl		 PMID:26479788 GO_REF:0000107 NCBI chr11:78,320,225...78,329,837
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16601681)		 UniProt
RGD		 PMID:16601681 GO_REF:0000024 NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:22483866) RGD PMID:22483866 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20628368)		 UniProt
Ensembl
RGD		 PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA		 (PMID:12421946)
GO_REF:0000107
(PMID:14688363)		 RGD
Ensembl		 PMID:12421946 PMID:14688363 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:12421946) RGD PMID:12421946 NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA
IBA		 (PMID:12421946)
GO_REF:0000107
GO_REF:0000033
(PMID:14688363)		 RGD
Ensembl
GO_Central		 PMID:12421946 PMID:14688363 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il23r interleukin 23 receptor involved_in ISO (PMID:12421946) RGD PMID:12421946 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:96,580,714...96,674,021 		JBrowse link
G Il27 interleukin 27 acts_upstream_of_or_within ISO
IEA		 MGI:107656 (PMID:25268627)
GO_REF:0000107		 RGD
Ensembl		 PMID:25268627 GO_REF:0000107 NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:181,173,372...181,178,582 		JBrowse link
G Il4 interleukin 4 IDA RGD PMID:9721086 RGD:8142392 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:16127453), (PMID:19609254), (PMID:20628368)
MGI:3654145 (PMID:18780793)
GO_REF:0000024		 RGD
UniProt		 PMID:16127453 PMID:18780793 PMID:19609254 PMID:20628368 GO_REF:0000024 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO
IEA		 UniProtKB:P42224|UniProtKB:Q8TDB6 (PMID:26479788)
GO_REF:0000107		 RGD
Ensembl		 PMID:26479788 GO_REF:0000107 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:16873256)
(PMID:16873257)		 RGD PMID:16873256 PMID:16873257 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26046437)		 UniProt
Ensembl
RGD		 PMID:26046437 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:17,275,445...17,280,018
Ensembl chr  X:14,603,539...14,608,087 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:19158675)
GO_REF:0000107		 RGD
Ensembl		 PMID:19158675 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO
IEA		 (PMID:19609254)
GO_REF:0000107		 RGD
Ensembl		 PMID:19609254 GO_REF:0000107 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Selenok selenoprotein K involved_in ISO
IEA		 (PMID:21220695)
GO_REF:0000107		 RGD
Ensembl		 PMID:21220695 GO_REF:0000107 NCBI chr16:5,158,601...5,167,183
Ensembl chr16:5,152,066...5,159,188 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO
IEA		 (PMID:22783022)
GO_REF:0000107		 RGD
Ensembl		 PMID:22783022 GO_REF:0000107 NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 involved_in ISO UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6 (PMID:26479788) RGD PMID:26479788 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:18818105)
GO_REF:0000107		 RGD
Ensembl		 PMID:18818105 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20628368)		 Ensembl
UniProt
RGD		 PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:56,847,837...56,886,302
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO
IEA		 (PMID:23066157)
GO_REF:0000107		 RGD
Ensembl		 PMID:23066157 GO_REF:0000107 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
G Trim44 tripartite motif-containing 44 involved_in ISO (PMID:23460740) RGD PMID:23460740 NCBI chr 3:109,048,643...109,183,821
Ensembl chr 3:88,592,719...88,729,188 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO
IEA		 (PMID:24882218)
GO_REF:0000107		 RGD
Ensembl		 PMID:24882218 GO_REF:0000107 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO
IEA		 (PMID:23355615)
GO_REF:0000107		 RGD
Ensembl		 PMID:23355615 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO (PMID:25299331) RGD PMID:25299331 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 involved_in ISO (PMID:29429998) RGD PMID:29429998 NCBI chr 1:31,124,900...31,156,075
Ensembl chr 1:29,296,334...29,326,898 		JBrowse link
regulation of defense response to virus by host term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:28636595) RGD PMID:28636595 NCBI chr13:68,152,813...68,189,580
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in ISO (PMID:24784232) RGD PMID:24784232 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:24784232) RGD PMID:24784232 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifnlr1 interferon, lambda receptor 1 involved_in ISO
IEA		 (PMID:12469119)
GO_REF:0000107		 RGD
Ensembl		 PMID:12469119 GO_REF:0000107 NCBI chr 5:153,203,597...153,225,911
Ensembl chr 5:147,919,908...147,942,332 		JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO
IEA		 MGI:2136897 (PMID:10704459)
GO_REF:0000107		 RGD
Ensembl		 PMID:10704459 GO_REF:0000107 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Rnf216 ring finger protein 216 involved_in ISO (PMID:19893624) RGD PMID:19893624 NCBI chr12:16,568,327...16,689,868
Ensembl chr12:11,454,797...11,576,304 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 IDA RGD PMID:12215647 RGD:634516 NCBI chr 4:67,979,055...68,029,353
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to biotic stimulus 1943
        regulation of response to biotic stimulus 600
          regulation of defense response to virus 67
            negative regulation of defense response to virus + 18
            regulation of defense response to virus by host + 45
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to external stimulus 2804
        response to external biotic stimulus 1894
          response to other organism 1890
            response to virus 393
              defense response to virus 299
                regulation of defense response to virus 67
                  negative regulation of defense response to virus + 18
                  regulation of defense response to virus by host + 45
paths to the root