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ONTOLOGY REPORT - ANNOTATIONS

Term:hydrogen peroxide biosynthetic process
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Accession:GO:0050665 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms:exact_synonym: H2O2 biosynthetic process;   hydrogen peroxide anabolism;   hydrogen peroxide biosynthesis;   hydrogen peroxide formation;   hydrogen peroxide generation;   hydrogen peroxide synthesis


show annotations for term's descendants           Sort by:
hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,658,692...4,682,667
Ensembl chr 9:4,658,090...4,679,096 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in ISO PMID:8798532 BHF-UCL PMID:8798532 RGD:2317869 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893 		JBrowse link
G CYBB cytochrome b-245 beta chain acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14980704) Ensembl
MGI		 PMID:14980704 GO_REF:0000107 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14980704) Ensembl
MGI		 PMID:14980704 GO_REF:0000107 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G DUOX1 dual oxidase 1 involved_in ISO (PMID:19339556), (PMID:22814254) UniProt PMID:19339556 PMID:22814254 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G DUOX2 dual oxidase 2 involved_in ISO (PMID:16651268), (PMID:19339556), (PMID:22814254), (PMID:25761904) UniProt PMID:16651268 PMID:19339556 PMID:22814254 PMID:25761904 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO (PMID:15258578) MGI PMID:15258578 NCBI chr 6:5,702,222...5,719,515
Ensembl chr 6:5,605,694...5,719,458 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:15544046)
(PMID:14679182)		 RGD
UniProt
MGI		 PMID:10640619 PMID:12514262 PMID:14679182 PMID:15544046 PMID:15880490 RGD:1581090 RGD:1601266 RGD:634854 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15642720 RGD:2291946 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter ISO RGD PMID:26482480 RGD:12910938 NCBI chr 9:47,474,488...47,490,951
Ensembl chr 9:47,473,901...47,490,252 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:21410437 RGD:7349317 NCBI chr14:38,579,446...38,581,983
Ensembl chr14:38,579,446...38,581,983 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr 6:28,385,199...28,393,560 JBrowse link
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:11,546,285...11,555,715
Ensembl chr30:11,547,014...11,555,110 		JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in ISO (PMID:16651268)
(PMID:22814254)		 UniProt PMID:16651268 PMID:22814254 NCBI chr30:11,541,849...11,546,019
Ensembl chr30:11,542,078...11,545,811 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:27279484 RGD:151347625 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G ZNF205 zinc finger protein 205 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,085,069...38,095,012
Ensembl chr 6:38,085,231...38,097,678 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      cellular metabolic process 9218
        cellular biosynthetic process 7461
          hydrogen peroxide biosynthetic process 21
            negative regulation of hydrogen peroxide biosynthetic process 6
            positive regulation of hydrogen peroxide biosynthetic process 6
            regulation of hydrogen peroxide biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      cellular metabolic process 9218
        reactive oxygen species metabolic process 277
          reactive oxygen species biosynthetic process 77
            hydrogen peroxide biosynthetic process 21
              negative regulation of hydrogen peroxide biosynthetic process 6
              positive regulation of hydrogen peroxide biosynthetic process 6
              regulation of hydrogen peroxide biosynthetic process + 12
paths to the root