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ONTOLOGY REPORT - ANNOTATIONS


Term:NADP binding
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Accession:GO:0050661 term browser browse the term
Definition:Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
Synonyms:exact_synonym: nicotinamide adenine dinucleotide phosphate binding
 related_synonym: NADP or NADPH binding



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NADP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025010.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr16:46,413,378...46,414,771 JBrowse link
G AABR07030729.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:98,813,794...98,814,795 JBrowse link
G AABR07032392.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr18:61,627,156...61,628,375 JBrowse link
G AABR07034445.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07070043.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:41,698,712...41,717,583 JBrowse link
G AABR07071101.1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 8:93,369,066...93,370,460 JBrowse link
G Aspdh aspartate dehydrogenase domain containing enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Cat catalase enables ISO (PMID:10656833) RGD PMID:10656833 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Crym crystallin, mu enables ISO (PMID:17242435) RGD PMID:17242435 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhfr dihydrofolate reductase enables IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:3970530 PMID:21873635 RGD:2300196, RGD:13792537 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase enables IDA
IBA
ISO
PMID:21873635
(PMID:11988088), (PMID:8373446)
RGD PMID:8373446 PMID:11988088 PMID:7626590 PMID:21873635 PMID:8373446 RGD:1624989, RGD:13792537, RGD:8553278 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G ENSRNOG00000066288 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:126,349,552...126,350,664 JBrowse link
G ENSRNOG00000067830 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 3:126,310,006...126,311,118 JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo13 flavin-containing monooxygenase 13 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:78,726,398...78,738,178
Ensembl chr13:78,726,398...78,738,178
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 enables IPI
IEA
GO_REF:0000002 InterPro
RGD
PMID:17173378 GO_REF:0000002, RGD:1626480 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fmo6 flavin containing monooxygenase 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:75,256,617...75,288,167
Ensembl chr13:75,260,368...75,288,769
JBrowse link
G Fmo9 flavin containing monooxygenase 9 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:78,820,080...78,841,075
Ensembl chr13:78,820,080...78,841,075
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase enables IDA
ISO
IMP
(PMID:15858258) RGD PMID:15858258 PMID:17447164 PMID:16325866 RGD:1624966, RGD:1624987 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640
JBrowse link
G Glyr1 glyoxylate reductase 1 homolog enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:10,532,036...10,567,639
Ensembl chr10:10,532,154...10,567,637
JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase IDA RGD PMID:2689175 RGD:1599320 NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603
JBrowse link
G Gsr glutathione-disulfide reductase enables IDA
IEA
GO_REF:0000002 InterPro
RGD
PMID:237922 GO_REF:0000002, RGD:1625133 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IDA RGD PMID:6813321 RGD:1641956 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 enables IDA
ISO
(PMID:15513927), (PMID:17919905), (PMID:18069989), (PMID:18485702), (PMID:18553955), (PMID:19217779) RGD PMID:15513927 PMID:17919905 PMID:18069989 PMID:18485702 PMID:18553955 More... RGD:1625105 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 enables ISO (PMID:8805577) RGD PMID:8805577 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 IDA RGD PMID:17447164 RGD:1624966 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Kif1b kinesin family member 1B enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G LOC108352348 glyceraldehyde-3-phosphate dehydrogenase pseudogene enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:68,857,943...68,859,024
Ensembl chr11:68,857,943...68,858,944
JBrowse link
G LOC303448 similar to glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:75,960,507...75,968,953
Ensembl chr10:75,962,608...75,963,615
JBrowse link
G LOC685351 similar to flavin containing monooxygenase 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:78,789,759...78,804,900
Ensembl chr13:78,790,856...78,804,900
JBrowse link
G Me1 malic enzyme 1 IDA RGD PMID:17447164 RGD:1624966 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Miox myo-inositol oxygenase IDA RGD PMID:10944187 RGD:631888 NCBI chr 7:120,405,031...120,407,529
Ensembl chr 7:120,405,031...120,407,537
JBrowse link
G Mthfr methylenetetrahydrofolate reductase IDA RGD PMID:11730351 RGD:1601423 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO (PMID:15900210) RGD PMID:15900210 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase enables IBA
ISO
PMID:21873635
(PMID:10673423)
RGD PMID:10673423 PMID:21873635 RGD:13792537 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
G Nos1 nitric oxide synthase 1 enables IDA
IEA
PMID:17029414
GO_REF:0000002
InterPro
RGD
PMID:17029414 PMID:17029414 GO_REF:0000002, RGD:1598372, RGD:1598372 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pgd phosphogluconate dehydrogenase enables IDA
IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro
RGD
PMID:17447164 PMID:21873635 PMID:6813321 GO_REF:0000002, RGD:1624966, RGD:13792537, RGD:1641956 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Por cytochrome p450 oxidoreductase IDA
IMP
RGD PMID:9774150 PMID:16928691 RGD:1599688, RGD:1599694 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G RGD1564958 similar to glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:15,370,290...15,371,300
Ensembl chr16:15,370,293...15,371,300
JBrowse link
NADP+ binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO
GO_REF:0000107
(MGI:5883408|PMID:20124700)
Ensembl
RGD
PMID:20124700 GO_REF:0000107 MGI:5883408 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase enables ISO
ISS
(PMID:9525924)
GO_REF:0000024
RGD
UniProt
PMID:9525924 GO_REF:0000024 NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 enables ISO (PMID:9525918) RGD PMID:9525918 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Me3 malic enzyme 3 enables ISO (PMID:7818469) RGD PMID:7818469 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132
JBrowse link
NADPH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO
GO_REF:0000107
(MGI:5883408|PMID:20124700)
Ensembl
RGD
PMID:20124700 GO_REF:0000107 MGI:5883408 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Cbr3 carbonyl reductase 3 enables ISO (PMID:18493841) RGD PMID:18493841 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO
ISS
(PMID:19000905), (PMID:25203508)
GO_REF:0000024
RGD
UniProt
PMID:19000905 PMID:25203508 GO_REF:0000024 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712
JBrowse link
G Cryz crystallin zeta enables IBA
ISO
ISS
PMID:21873635
(PMID:17497241)
GO_REF:0000024
RGD
UniProt
PMID:17497241 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Cryzl2 crystallin zeta like 2 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 enables ISO
IEA
(PMID:15531764)
GO_REF:0000107
RGD
Ensembl
PMID:15531764 GO_REF:0000107 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:26429968) RGD PMID:26429968 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
JBrowse link
G Fdxr ferredoxin reductase IDA RGD PMID:10525147 RGD:727285 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase enables ISO (PMID:16756993) RGD PMID:16756993 NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase enables ISO (PMID:10698924) RGD PMID:10698924 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables ISO
ISS
(PMID:17540341)
GO_REF:0000024
RGD
UniProt
PMID:17540341 GO_REF:0000024 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Lbr lamin B receptor enables ISS
ISO
GO_REF:0000024
(PMID:27336722)
UniProt
RGD
PMID:27336722 GO_REF:0000024 NCBI chr13:93,539,360...93,564,065
Ensembl chr13:93,538,920...93,564,017
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO (PMID:10625700) RGD PMID:10625700 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860
JBrowse link
G Nos1 nitric oxide synthase 1 IDA RGD PMID:14966111 RGD:1358520 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Qdpr quinoid dihydropteridine reductase enables IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:1639779 PMID:21873635 RGD:5128591, RGD:13792537 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:11377984 RGD:4891997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr 6:27,818,327...27,827,030 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19541
    binding 16792
      small molecule binding 2443
        nucleotide binding 2067
          NADP binding 66
            NADP+ binding 5
            NADPH binding 20
Path 2
Term Annotations click to browse term
  molecular_function 19541
    binding 16792
      organic cyclic compound binding 5667
        nucleoside phosphate binding 2067
          nucleotide binding 2067
            NADP binding 66
              NADP+ binding 5
              NADPH binding 20
paths to the root