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ONTOLOGY REPORT - ANNOTATIONS

Term:catecholamine secretion
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Accession:GO:0050432 term browser browse the term
Definition:The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.

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catecholamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator acts_upstream_of_or_within ISO (PMID:15820695) MGI PMID:15820695 NCBI chrNW_004955517:2,965,471...3,420,183 JBrowse link
G Mecp2 methyl-CpG binding protein 2 acts_upstream_of ISO (PMID:17050729) MGI PMID:17050729 NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288 		JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of ISO (PMID:17563363) MGI PMID:17563363 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of ISO (PMID:9428762) MGI PMID:9428762 NCBI chrNW_004955545:1,065,457...1,077,056
Ensembl chrNW_004955545:1,065,457...1,077,526 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:12188925), (PMID:17881525)
(PMID:24509724)
(PMID:24639487), (PMID:30238463)		 MGI PMID:12188925 PMID:17881525 PMID:24509724 PMID:24639487 PMID:30238463 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412 		JBrowse link
G Gnat1 G protein subunit alpha transducin 1 acts_upstream_of_or_within ISO (PMID:30799247) MGI PMID:30799247 NCBI chrNW_004955532:2,018,850...2,023,603
Ensembl chrNW_004955532:2,018,850...2,023,603 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 acts_upstream_of_positive_effect ISO (PMID:32273471) UniProt PMID:32273471 NCBI chrNW_004955448:11,025,095...11,094,053
Ensembl chrNW_004955448:11,025,095...11,093,429 		JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of ISO (PMID:17563363) MGI PMID:17563363 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
G Tgm2 transglutaminase 2 acts_upstream_of_positive_effect ISO (PMID:32273471) UniProt PMID:32273471 NCBI chrNW_004955445:18,544,192...18,576,576
Ensembl chrNW_004955445:18,544,183...18,576,570 		JBrowse link
negative regulation of catecholamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A involved_in ISO (PMID:15326220) UniProt PMID:15326220 NCBI chrNW_004955438:15,092,267...15,104,321
Ensembl chrNW_004955438:15,092,394...15,104,381 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (PMID:20735850) ParkinsonsUK-UCL PMID:20735850 RGD:11535092 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
negative regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase ISO RGD PMID:590329 RGD:10047092 NCBI chrNW_004955442:9,422,849...9,516,054
Ensembl chrNW_004955442:9,422,849...9,516,103 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:19187091 RGD:2314679 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:16490190 RGD:1625068 NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chrNW_004955507:2,035,918...2,141,327
Ensembl chrNW_004955507:2,036,050...2,137,377 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:12872287 RGD:2315496 NCBI chrNW_004955583:85,255...115,140
Ensembl chrNW_004955583:85,255...115,189 		JBrowse link
G Myo5a myosin VA ISO RGD PMID:22639889 RGD:42722007 NCBI chrNW_004955409:2,409,503...2,530,539
Ensembl chrNW_004955409:2,428,815...2,530,012 		JBrowse link
G Syt11 synaptotagmin 11 involved_in ISO (MGI:6114813|PMID:29311685) UniProt PMID:29311685 MGI:6114813 RGD:14929208 NCBI chrNW_004955545:2,054,720...2,074,526
Ensembl chrNW_004955545:2,054,721...2,074,526 		JBrowse link
negative regulation of epinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO RGD PMID:12606499 RGD:704397 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:12606499 RGD:704397 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17194738 RGD:5131263 NCBI chrNW_004955410:31,830,333...31,874,384
Ensembl chrNW_004955410:31,828,506...31,875,100 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO RGD PMID:14568556 RGD:2315495 NCBI chrNW_004955583:85,255...115,140
Ensembl chrNW_004955583:85,255...115,189 		JBrowse link
G Gck glucokinase ISO down-regulation of the counterregulatory response to insulin-induced hypoglycemia RGD PMID:18292346 RGD:2301900 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18598693 RGD:2300224 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
negative regulation of norepinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:18670361 RGD:6903961 NCBI chrNW_004955534:3,653,112...3,654,248
Ensembl chrNW_004955534:3,653,157...3,654,248 		JBrowse link
G Crh corticotropin releasing hormone ISO RGD PMID:12606499 RGD:704397 NCBI chrNW_004955444:12,989,210...12,991,300 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17194738 RGD:5131263 NCBI chrNW_004955410:31,830,333...31,874,384
Ensembl chrNW_004955410:31,828,506...31,875,100 		JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:17911350 RGD:12907501 NCBI chrNW_004955420:2,483,173...2,486,414
Ensembl chrNW_004955420:2,478,877...2,487,215 		JBrowse link
G P2ry1 purinergic receptor P2Y1 ISO RGD PMID:19447154 RGD:2315789 NCBI chrNW_004955448:4,366,706...4,372,626
Ensembl chrNW_004955448:4,366,706...4,372,626 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:19447154 RGD:2315789 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:12524145 RGD:10043195 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18598693 RGD:2300224 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
norepinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:12188925) MGI PMID:12188925 NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412 		JBrowse link
G Nisch nischarin ISO RGD PMID:15028598 RGD:1582691 NCBI chrNW_004955430:2,443,029...2,488,267
Ensembl chrNW_004955430:2,443,029...2,491,123 		JBrowse link
positive regulation of catecholamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO RGD PMID:18823369 RGD:2316113 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in ISO PMID:18223549 BHF-UCL PMID:18223549 RGD:8553863 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in ISO PMID:20484665 UniProt PMID:20484665 RGD:10047179 NCBI chrNW_004955445:8,680,979...8,779,662
Ensembl chrNW_004955445:8,680,965...8,774,110 		JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of_or_within ISO (PMID:17563363) MGI PMID:17563363 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
G Stx1a syntaxin 1A involved_in ISO PMID:20484665 UniProt PMID:20484665 RGD:10047179 NCBI chrNW_004955456:14,030,233...14,046,456
Ensembl chrNW_004955456:14,030,226...14,046,456 		JBrowse link
positive regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:9428762) MGI PMID:9428762 NCBI chrNW_004955545:1,065,457...1,077,056
Ensembl chrNW_004955545:1,065,457...1,077,526 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO RGD PMID:18671738 RGD:2306573 NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO RGD PMID:16987217 RGD:2317005 NCBI chrNW_004955452:323,641...338,312 JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO RGD PMID:17382974 RGD:1642505 NCBI chrNW_004955471:11,796,278...11,804,114
Ensembl chrNW_004955471:11,796,278...11,804,114 		JBrowse link
G Oprk1 opioid receptor kappa 1 ISO RGD PMID:17568430 RGD:9831445 NCBI chrNW_004955454:12,741,577...12,751,282
Ensembl chrNW_004955454:12,744,765...12,752,226 		JBrowse link
G Pcp4 Purkinje cell protein 4 ISO RGD PMID:21671256 RGD:9850149 NCBI chrNW_004955407:39,853,029...39,908,151
Ensembl chrNW_004955407:39,853,034...39,908,151 		JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of_or_within ISO (PMID:17563363) MGI PMID:17563363 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
G Rtn4 reticulon 4 ISO RGD PMID:19112410 RGD:2314933 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Slc18a1 solute carrier family 18 member A1 ISO RGD PMID:17244889 RGD:5131195 NCBI chrNW_004955403:43,821,978...43,848,403
Ensembl chrNW_004955403:43,821,296...43,848,399 		JBrowse link
G Syt1 synaptotagmin 1 involved_in ISO PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chrNW_004955405:17,840,012...18,372,156
Ensembl chrNW_004955405:17,839,884...18,372,566 		JBrowse link
positive regulation of epinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide involved_in ISO (PMID:11711504) HGNC-UCL PMID:11711504 NCBI chrNW_004955575:551,991...555,118
Ensembl chrNW_004955575:551,991...555,149 		JBrowse link
positive regulation of norepinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO RGD PMID:15223300 RGD:2316128 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 involved_in ISO PMID:18167541 UniProt PMID:18167541 RGD:10047360 NCBI chrNW_004955445:8,680,979...8,779,662
Ensembl chrNW_004955445:8,680,965...8,774,110 		JBrowse link
G Oxtr oxytocin receptor ISO RGD PMID:14656297 RGD:2304181 NCBI chrNW_004955561:340,387...354,499
Ensembl chrNW_004955561:337,902...354,336 		JBrowse link
G Plcd1 phospholipase C delta 1 ISO RGD PMID:10473563 RGD:2301014 NCBI chrNW_004955421:4,856,366...4,880,309
Ensembl chrNW_004955421:4,856,366...4,880,309 		JBrowse link
G Stx1a syntaxin 1A involved_in ISO PMID:18167541 UniProt PMID:18167541 RGD:10047360 NCBI chrNW_004955456:14,030,233...14,046,456
Ensembl chrNW_004955456:14,030,226...14,046,456 		JBrowse link
regulation of catecholamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdhd succinate dehydrogenase complex subunit D acts_upstream_of_or_within ISO (PMID:15572694) MGI PMID:15572694 NCBI chrNW_004955412:13,768,501...13,778,944
Ensembl chrNW_004955412:13,768,501...13,778,932 		JBrowse link
regulation of dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit acts_upstream_of_or_within ISO (PMID:12944511) MGI PMID:12944511 NCBI chrNW_004955528:825,314...840,994
Ensembl chrNW_004955528:825,308...841,270 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit acts_upstream_of_or_within ISO (PMID:12944511) MGI PMID:12944511 NCBI chrNW_004955536:166,212...172,551
Ensembl chrNW_004955536:166,212...172,551 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:12944511) MGI PMID:12944511 NCBI chrNW_004955545:1,065,457...1,077,056
Ensembl chrNW_004955545:1,065,457...1,077,526 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:9482807)
(PMID:12044470)		 RGD
MGI		 PMID:9482807 PMID:12044470 PMID:16490190 RGD:1625068 NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 involved_in ISO (MGI:4398782|PMID:19887632) UniProt PMID:19887632 MGI:4398782 NCBI chrNW_004955590:276,143...382,812
Ensembl chrNW_004955590:281,704...386,189 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO RGD PMID:30283001 RGD:38501063 NCBI chrNW_004955532:3,309,034...3,320,954
Ensembl chrNW_004955532:3,309,028...3,320,966 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO RGD PMID:16885935 RGD:1626459 NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:15999145 RGD:1624397 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 involved_in ISO (MGI:4947004|PMID:21233214) UniProt PMID:21233214 MGI:4947004 NCBI chrNW_004955435:14,074,346...14,080,026
Ensembl chrNW_004955435:14,074,346...14,078,806 		JBrowse link
G Prkcb protein kinase C beta ISO RGD PMID:15647254 RGD:1625522 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in ISO PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chrNW_004955524:3,220,108...3,224,376
Ensembl chrNW_004955524:3,221,366...3,224,376 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO (PMID:18333965) MGI PMID:18333965 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403 		JBrowse link
G Sncg synuclein gamma acts_upstream_of_or_within ISO (PMID:18333965) MGI PMID:18333965 NCBI chrNW_004955510:5,958,276...5,961,719
Ensembl chrNW_004955510:5,958,276...5,961,719 		JBrowse link
G Syt1 synaptotagmin 1 involved_in ISO (MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:5795818 NCBI chrNW_004955405:17,840,012...18,372,156
Ensembl chrNW_004955405:17,839,884...18,372,566 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:5795818 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:5795818|PMID:21576241) ParkinsonsUK-UCL PMID:21576241 MGI:5795818 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651 		JBrowse link
regulation of norepinephrine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO RGD PMID:16539684 RGD:1625639 NCBI chrNW_004955455:7,886,720...7,906,214
Ensembl chrNW_004955455:7,895,974...7,906,505 		JBrowse link
G Agt angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit acts_upstream_of_or_within ISO (PMID:10942027) MGI PMID:10942027 NCBI chrNW_004955416:30,687,518...30,798,700
Ensembl chrNW_004955416:30,687,478...30,798,700 		JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISO (MGI:5429475|PMID:22673524) UniProt PMID:22673524 MGI:5429475 NCBI chrNW_004955468:4,627,686...4,634,499 JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:15076218 RGD:1626433 NCBI chrNW_004955528:1,819,247...1,826,707
Ensembl chrNW_004955528:1,819,247...1,826,707 		JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:12524145 RGD:10043195 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
somato-dendritic dopamine secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a2 solute carrier family 18 member A2 involved_in ISO PMID:16301178 UniProt PMID:16301178 RGD:155663549 NCBI chrNW_004955431:21,949,553...21,979,679
Ensembl chrNW_004955431:21,949,576...21,979,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      export from cell 921
        secretion by cell 860
          catecholamine secretion 63
            catecholamine secretion, neurotransmission + 0
            dopamine secretion + 36
            epinephrine secretion + 7
            negative regulation of catecholamine secretion + 19
            norepinephrine secretion + 20
            positive regulation of catecholamine secretion + 17
            regulation of catecholamine secretion + 55
Path 2
Term Annotations click to browse term
  biological_process 12346
    localization 4270
      establishment of localization 3607
        transport 3331
          organic substance transport 1661
            organic hydroxy compound transport 266
              catecholamine transport 80
                catecholamine secretion 63
                  catecholamine secretion, neurotransmission + 0
                  dopamine secretion + 36
                  epinephrine secretion + 7
                  negative regulation of catecholamine secretion + 19
                  norepinephrine secretion + 20
                  positive regulation of catecholamine secretion + 17
                  regulation of catecholamine secretion + 55
paths to the root