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ONTOLOGY REPORT - ANNOTATIONS

Term:transforming growth factor beta binding
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Accession:GO:0050431 term browser browse the term
Definition:Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
Synonyms:exact_synonym: TGF-beta binding;   TGFbeta binding
 related_synonym: transforming growth factor beta ligand binding to type I receptor;   transforming growth factor beta ligand binding to type II receptor

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transforming growth factor beta binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 enables IEA
ISO		 GO_REF:0000107
(MGI:2181509|PMID:12054694)
(PMID:8242742)		 Ensembl
RGD		 PMID:8242742 PMID:12054694 GO_REF:0000107 MGI:2181509 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930 		JBrowse link
G Acvr2b activin A receptor type 2B NOT|enables ISO (MGI:51043|PMID:1326537) RGD PMID:1326537 MGI:51043 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746 		JBrowse link
G Acvrl1 activin A receptor like type 1 enables ISO UniProtKB:P07200 (PMID:8242742) RGD PMID:8242742 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335 		JBrowse link
G Agrn agrin IPI RGD PMID:20505824 RGD:8549766 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645 		JBrowse link
G Cd109 CD109 molecule enables ISO UniProtKB:P01137 (PMID:16754747) RGD PMID:16754747 NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409 		JBrowse link
G Cd36 CD36 molecule enables IDA PMID:10487979 BHF-UCL PMID:10487979 RGD:2317966 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Eng endoglin contributes_to
enables		 ISO
IBA		 UniProtKB:P07200|UniProtKB:P10600 (PMID:9872992)
(MGI:66318|PMID:8194490)
PMID:21873635
UniProtKB:P01137|UniProtKB:P10600 (PMID:1326540)
UniProtKB:P01137 (PMID:8370410)		 RGD PMID:1326540 PMID:8194490 PMID:8370410 PMID:9872992, PMID:21873635 MGI:66318, RGD:13792537 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485 		JBrowse link
G Hyal2 hyaluronidase 2 enables IEA
ISO		 GO_REF:0000107
UniProtKB:P01137 (MGI:3851310|PMID:19366691)		 Ensembl
RGD		 PMID:19366691 GO_REF:0000107 MGI:3851310 NCBI chr 8:116,324,062...116,328,978
Ensembl chr 8:116,324,040...116,328,978 		JBrowse link
G Lrrc32 leucine rich repeat containing 32 enables ISO UniProtKB:P01137|UniProtKB:P61812 (PMID:19651619), (PMID:22278742)
UniProtKB:P17125 (MGI:5920420|PMID:28912269)		 RGD PMID:19651619 PMID:22278742 PMID:28912269 MGI:5920420 NCBI chr 1:163,443,972...163,457,426
Ensembl chr 1:163,445,527...163,457,424 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 enables ISO
IEA		 UniProtKB:P01137|UniProtKB:P10600|UniProtKB:P61812 (PMID:10930463), (PMID:18672106), (PMID:2022183), (PMID:8617200)
GO_REF:0000107		 RGD
Ensembl		 PMID:2022183 PMID:8617200 PMID:10930463 PMID:18672106 GO_REF:0000107 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 enables ISO UniProtKB:P01137|UniProtKB:P10600|UniProtKB:P61812 (PMID:10930463), (PMID:18672106) RGD PMID:10930463 PMID:18672106 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 enables ISO
IBA		 UniProtKB:P01137 (PMID:10930463), (PMID:9660815)
PMID:21873635		 RGD PMID:9660815 PMID:10930463, PMID:21873635 RGD:13792537 NCBI chr 1:84,118,046...84,152,095
Ensembl chr 1:84,118,046...84,150,084 		JBrowse link
G Nrros negative regulator of reactive oxygen species enables ISO UniProtKB:P01137 (PMID:29909984)
UniProtKB:P04202 (MGI:6192878|PMID:29909984)		 RGD PMID:29909984 MGI:6192878 NCBI chr11:71,872,728...71,889,897
Ensembl chr11:71,872,830...71,889,887 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 enables ISO
ISS		 (PMID:18243111)
GO_REF:0000024		 RGD
AgBase		 PMID:18243111 GO_REF:0000024 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 enables
contributes_to		 IDA
ISO
ISS		 PR:P04202 (MGI:3766844|PMID:17878231)
GO_REF:0000024
UniProtKB:P01137 (PMID:1326540), (PMID:14633705)
(PMID:11157754), (PMID:1333888)		 RGD
AgBase		 PMID:1326540 PMID:1333888 PMID:11157754 PMID:14633705 PMID:17878231, PMID:8272871 GO_REF:0000024 MGI:3766844, RGD:737663 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 contributes_to
enables		 ISO
IBA		 UniProtKB:P61812 (PMID:7852346)
PR:P04202 (MGI:3766844|PMID:17878231)
UniProtKB:P01137|UniProtKB:P10600|UniProtKB:P61812 (PMID:1326540), (PMID:1333888), (PMID:18243111), (PMID:18453574), (PMID:7852346)
(PMID:11157754)
PMID:21873635
UniProtKB:P61812 (PMID:11157754)		 RGD PMID:1326540 PMID:1333888 PMID:7852346 PMID:11157754 PMID:17878231 PMID:18243111 PMID:18453574, PMID:21873635 MGI:3766844, RGD:13792537 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 enables
contributes_to		 IDA
ISO
NAS
IBA
IPI		 (MGI:3699491|PMID:17295310)
PMID:1333192
PMID:8106553
(PMID:11157754), (PMID:12958365)
PMID:21873635
UniProtKB:P61812 (PMID:11157754)
PMID:7852346		 RGD PMID:11157754 PMID:12958365 PMID:17295310, PMID:1657407, PMID:1333192, PMID:8106553, PMID:21873635, PMID:7852346, PMID:1744125 MGI:3699491, RGD:729942, RGD:8554613, RGD:1579949, RGD:13792537, RGD:8553463, RGD:2302518 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545 		JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like contributes_to IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:2,540,494...2,545,315
Ensembl chr12:2,542,612...2,545,740 		JBrowse link
G Thbs1 thrombospondin 1 IDA RGD PMID:10487979 RGD:2317966 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan enables IEA
ISO
ISS
IBA		 GO_REF:0000107
UniProtKB:P04202 (MGI:5449316|PMID:22995554)
GO_REF:0000024
PMID:21873635		 Ensembl
RGD
UniProt		 PMID:22995554, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5449316, RGD:13792537 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 enables ISO (PMID:17164348) RGD PMID:17164348 NCBI chr 9:113,699,151...113,732,601
Ensembl chr 9:113,699,170...113,732,622 		JBrowse link
G Vasn vasorin enables ISO
IBA		 UniProtKB:P01137 (PMID:15247411)
PMID:21873635		 RGD PMID:15247411, PMID:21873635 RGD:13792537 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548 		JBrowse link
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 enables ISO
IBA		 (PMID:21054789)
PMID:21873635		 RGD PMID:21054789, PMID:21873635 RGD:13792537 NCBI chr10:15,243,429...15,245,757
Ensembl chr10:15,243,429...15,245,757 		JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 enables IBA
ISO		 PMID:21873635
UniProtKB:O14793 (PMID:12595574), (PMID:21054789)		 RGD PMID:12595574 PMID:21054789, PMID:21873635 RGD:13792537 NCBI chr10:81,936,156...81,943,142
Ensembl chr10:81,936,444...81,942,188 		JBrowse link
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  molecular_function 20074
    binding 17039
      protein binding 14343
        cytokine binding 146
          transforming growth factor beta binding 24
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