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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta binding
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Accession:GO:0050431 term browser browse the term
Definition:Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
Synonyms:exact_synonym: TGF-beta binding;   TGFbeta binding
 related_synonym: transforming growth factor beta ligand binding to type I receptor;   transforming growth factor beta ligand binding to type II receptor


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transforming growth factor beta binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 enables ISO (PMID:8242742)
(MGI:2181509|PMID:12054694)
UniProt
MGI
PMID:8242742 PMID:12054694 MGI:2181509 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G ACVR2B activin A receptor type 2B NOT|enables ISO (MGI:51043|PMID:1326537) MGI PMID:1326537 MGI:51043 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
JBrowse link
G ACVRL1 activin A receptor like type 1 enables ISO (PMID:8242742) UniProt PMID:8242742 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691
JBrowse link
G AGRN agrin ISO RGD PMID:20505824 RGD:8549766 Ensembl chr 1:936,000...966,808 JBrowse link
G CD109 CD109 molecule enables ISO (PMID:16754747) UniProt PMID:16754747 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414
JBrowse link
G CD36 CD36 molecule enables ISO PMID:10487979 BHF-UCL PMID:10487979 RGD:2317966 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G ENG endoglin contributes_to
enables
ISO (PMID:9872992)
(MGI:66318|PMID:8194490)
(PMID:1326540)
(PMID:1326540), (PMID:8370410)
BHF-UCL PMID:1326540 PMID:8194490 PMID:8370410 PMID:9872992 MGI:66318 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G HYAL2 hyaluronidase 2 enables ISO (MGI:3851310|PMID:19366691) BHF-UCL PMID:19366691 MGI:3851310 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551
JBrowse link
G LRRC32 leucine rich repeat containing 32 enables ISO (PMID:19651619)
(MGI:5920420|PMID:28912269)
(PMID:22278742)
UniProt PMID:19651619 PMID:22278742 PMID:28912269 MGI:5920420 NCBI chr11:71,708,222...71,721,426
Ensembl chr11:75,354,997...75,367,440
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 enables ISO (PMID:10930463)
(PMID:10930463), (PMID:2022183), (PMID:8617200)
(PMID:10930463), (PMID:18672106), (PMID:2022183), (PMID:8617200)
UniProt PMID:2022183 PMID:8617200 PMID:10930463 PMID:18672106 NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 enables ISO (PMID:10930463), (PMID:18672106) UniProt PMID:10930463 PMID:18672106 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 enables ISO (PMID:9660815)
(PMID:10930463)
UniProt PMID:9660815 PMID:10930463 NCBI chr19:37,637,509...37,674,791
Ensembl chr19:46,144,485...46,181,636
JBrowse link
G NRROS negative regulator of reactive oxygen species enables ISO (PMID:29909984)
(MGI:6192878|PMID:29909984)
UniProt PMID:29909984 MGI:6192878 NCBI chr 3:193,984,797...194,007,173
Ensembl chr 3:203,920,334...203,948,506
JBrowse link
G TGFB3 transforming growth factor beta 3 enables ISO (PMID:18243111) BHF-UCL PMID:18243111 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 contributes_to
enables
ISO (PMID:11157754)
(MGI:3766844|PMID:17878231)
(PMID:14633705)
(PMID:1326540)
(PMID:1333888)
BHF-UCL
MGI
HGNC-UCL
RGD
PMID:1326540 PMID:1333888 PMID:8272871 PMID:11157754 PMID:14633705 PMID:17878231 MGI:3766844 RGD:737663 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 contributes_to
enables
ISO (PMID:11157754), (PMID:7852346)
(MGI:3766844|PMID:17878231)
(PMID:1333888)
(PMID:1326540), (PMID:1333888)
(PMID:11157754), (PMID:18243111), (PMID:18453574), (PMID:7852346)
BHF-UCL
MGI
PMID:1326540 PMID:1333888 PMID:7852346 PMID:11157754 PMID:17878231 PMID:18243111 PMID:18453574 MGI:3766844 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 contributes_to
enables
ISO (PMID:11157754)
PMID:7852346
(PMID:11157754), (PMID:12958365)
PMID:8106553
(MGI:3699491|PMID:17295310)
RGD
BHF-UCL
PMID:1657407 PMID:1744125 PMID:7852346 PMID:8106553 PMID:11157754 PMID:12958365 PMID:17295310 MGI:3699491 RGD:1579949 RGD:2302518 RGD:729942 RGD:8553463 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G THBS1 thrombospondin 1 ISO RGD PMID:10487979 RGD:2317966 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G TSKU tsukushi, small leucine rich proteoglycan enables ISO (MGI:5449316|PMID:22995554) UniProt PMID:22995554 MGI:5449316 NCBI chr11:71,833,654...71,848,509
Ensembl chr11:75,492,912...75,493,973
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 enables ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr18:4,883,688...4,950,963
Ensembl chr18:7,164,091...7,229,271
JBrowse link
G VASN vasorin enables ISO (PMID:15247411) UniProt PMID:15247411 NCBI chr16:3,298,836...3,310,548
Ensembl chr16:4,475,506...4,477,527
JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 enables ISO (PMID:21054789) UniProt PMID:21054789
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 enables ISO (PMID:21054789)
(PMID:12595574)
UniProt PMID:12595574 PMID:21054789 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569
JBrowse link

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  molecular_function 14976
    binding 14174
      protein binding 13735
        cytokine binding 114
          transforming growth factor beta binding 23
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