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ONTOLOGY REPORT - ANNOTATIONS

Term:leukotriene-B4 20-monooxygenase activity
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Accession:GO:0050051 term browser browse the term
Definition:Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
Synonyms:related_synonym: LTB(4) 20-hydroxylase activity;   LTB(4) omega-hydroxylase activity;   LTB4 20-hydroxylase activity;   LTB4 omega-hydroxylase activity;   leukotriene-B4 20-hydroxylase activity;   leukotriene-B4 omega-hydroxylase activity
 xref: EC:1.14.14.94;   MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN;   RHEA:22176;   reactome:R-HSA-211873 "CYP4F2, 4F3 20-hydroxylate LTB4"


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leukotriene-B4 20-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 enables IDA
IBA
IEA 		PMID:14634044
PMID:10486137
GO_REF:0000033
GO_REF:0000003
GO_REF:0000116 		GO_Central
UniProt
RHEA		 PMID:14634044 PMID:10486137 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:2301710, RGD:2301713 NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 enables ISO
IBA 		(PMID:11461919), (PMID:9675028)
GO_REF:0000033 		RGD
GO_Central		 PMID:9675028 PMID:11461919 GO_REF:0000033 NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,740,001...17,838,958 		JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 enables IDA
IBA
IEA 		PMID:9344476
PMID:14634044
GO_REF:0000033
GO_REF:0000003
GO_REF:0000116 		GO_Central
UniProt
RHEA		 PMID:9344476 PMID:14634044 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116, RGD:15090848, RGD:2301710 NCBI chr 7:12,367,711...12,384,010
Ensembl chr 7:12,367,660...12,384,010 		JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:12,342,121...12,357,974
Ensembl chr 7:12,342,590...12,356,733 		JBrowse link
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