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ONTOLOGY REPORT - ANNOTATIONS

Term:stem cell fate specification
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Accession:GO:0048866 term browser browse the term
Definition:The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


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stem cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmrta2 DMRT-like family A2 acts_upstream_of_or_within ISO (PMID:21576465) RGD PMID:21576465 NCBI chr 5:124,805,883...124,811,694
Ensembl chr 5:124,805,883...124,811,630 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of ISO MGI:98956 (PMID:17462603) RGD PMID:17462603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO (PMID:20228271) RGD PMID:20228271 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO (PMID:20228271) RGD PMID:20228271 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsc goosecoid homeobox involved_in ISO (PMID:24290375) RGD PMID:24290375 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT|involved_in ISO (PMID:15073157) RGD PMID:15073157 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    developmental process 7070
      cellular developmental process 4782
        cell fate specification 102
          stem cell fate specification 6
            neural crest cell fate specification + 2
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular developmental process 4782
        cell differentiation 4781
          stem cell differentiation 286
            stem cell fate commitment 9
              stem cell fate specification 6
                neural crest cell fate specification + 2
paths to the root