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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:leukemia inhibitory factor signaling pathway
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Accession:GO:0048861 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a leukemia inhibitory factor to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: leukemia inhibitory factor signalling pathway


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leukemia inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctf1 cardiotrophin 1 IMP RGD PMID:15623435 RGD:1582264 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335 		JBrowse link
G Hesx1 HESX homeobox 1 acts_upstream_of_or_within ISO (PMID:31761678) RGD PMID:31761678 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 (PMID:12643274), (PMID:8999038)
GO_REF:0000107		 RGD
Ensembl		 PMID:8999038 PMID:12643274 GO_REF:0000107 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in IBA
ISO		 GO_REF:0000033
(PMID:12643274), (PMID:20624457), (PMID:22783022), (PMID:8999038)		 GO_Central
RGD		 PMID:8999038 PMID:12643274 PMID:20624457 PMID:22783022 GO_REF:0000033 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lifr LIF receptor subunit alpha involved_in ISO
IEA		 (PMID:12643274), (PMID:8999038)
GO_REF:0000107		 RGD
Ensembl		 PMID:8999038 PMID:12643274 GO_REF:0000107 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18525
      signal transduction 7080
        cell surface receptor signaling pathway 2822
          enzyme-linked receptor protein signaling pathway 1046
            leukemia inhibitory factor signaling pathway 5
              leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    biological regulation 13552
      regulation of biological process 13126
        signaling 7639
          signal transduction 7080
            cell surface receptor signaling pathway 2822
              enzyme-linked receptor protein signaling pathway 1046
                leukemia inhibitory factor signaling pathway 5
                  leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment 0
paths to the root