inner ear development - Ontology Report

MGI:3046273 (MGI:3629345|PMID:16775142)

PMID:16775142

MGI:3629345

NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688

Anp32b

acidic nuclear phosphoprotein 32 family member B

acts_upstream_of_or_within

MGI:5003050 (MGI:5003056|PMID:21636789)

PMID:21636789

MGI:5003056

NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717

atonal bHLH transcription factor 1

acts_upstream_of_or_within

MGI:3767172 (MGI:4939574|PMID:21146598)

PMID:21146598

MGI:4939574

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1856799 (MGI:3709803|PMID:11875276)

PMID:11875276

MGI:3709803

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

Bdnf

brain-derived neurotrophic factor

acts_upstream_of_or_within

MGI:1857136 (MGI:74182|PMID:7605630)

PMID:7605630

MGI:74182

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

Bmp2

bone morphogenetic protein 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5140238|PMID:21795542)

GO_REF:0000107 MGI:5140238

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

Bmper

BMP-binding endothelial regulator

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256

C1qb

complement C1q B chain

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5140238|PMID:21795542)

GO_REF:0000107 MGI:5140238

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

C1qtnf5

C1q and TNF related 5

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 8:44,450,934...44,453,075
Ensembl chr 8:44,451,154...44,453,074

Ccm2

CCM2 scaffold protein

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116

cadherin-related 23

acts_upstream_of_or_within

PMID:8790740 PMID:13336002 PMID:14759567

MGI:3027690 MGI:61338 MGI:79257 MGI:81497

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

Cdkn1b

cyclin-dependent kinase inhibitor 1B

acts_upstream_of_or_within

MGI:1857146 (MGI:1332249|PMID:10079221)

PMID:10079221

MGI:1332249

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

Cebpa

CCAAT/enhancer binding protein alpha

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

Cebpd

CCAAT/enhancer binding protein delta

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

Col2a1

collagen type II alpha 1 chain

acts_upstream_of_or_within

(MGI:1334159|PMID:10100048)

PMID:10100048

MGI:1334159

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Cxcl14

C-X-C motif chemokine ligand 14

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839

Cys1

cystin 1

acts_upstream_of_or_within

MGI:1856831 (MGI:49533|PMID:1952600)

PMID:1952600

MGI:49533

NCBI chr 6:41,300,836...41,318,071
Ensembl chr 6:41,300,836...41,318,071

Cytl1

cytokine like 1

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

delta like canonical Notch ligand 1

acts_upstream_of_or_within

MGI:1932522|MGI:3044907 (MGI:3621102|PMID:16495313)

PMID:16495313

MGI:3621102

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

Duox2

dual oxidase 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3712359 (MGI:3712355|PMID:17440044)

PMID:17440044

GO_REF:0000107 MGI:3712355

NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902

Esrrb

estrogen-related receptor beta

involved_in

GO_REF:0000024
(MGI:3722975|PMID:17765677)

PMID:17765677

GO_REF:0000024 MGI:3722975

NCBI chr 6:106,007,662...106,163,136
Ensembl chr 6:106,008,095...106,160,791

Eya4

EYA transcriptional coactivator and phosphatase 4

RGD

PMID:11159937

RGD:1598918

NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976

fibroblast growth factor receptor 3

acts_upstream_of_or_within

MGI:1931521 (MGI:3695846|PMID:17117437)

PMID:17117437

MGI:3695846

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

Frem2

FRAS1 related extracellular matrix 2

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

Gjb2

gap junction protein, beta 2

RGD

PMID:10570462

RGD:1599834

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

Gjb6

gap junction protein, beta 6

RGD

PMID:10570462

RGD:1599834

NCBI chr15:31,284,562...31,295,010
Ensembl chr15:31,284,419...31,294,582

Gli3

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:98297 (MGI:3709667|PMID:17395647)

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

glutaredoxin and cysteine rich domain containing 1

acts_upstream_of_or_within

MGI:1856991 (MGI:61338|PMID:13336002)

PMID:13336002

MGI:61338

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

homeobox A1

involved_in

(PMID:16155570)

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

Hoxa13

homeo box A13

acts_upstream_of_or_within

MGI:2152356 (MGI:3797428|PMID:18483557)

PMID:18483557

MGI:3797428

NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091

Hpca

hippocalcin

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841

Igf1

insulin-like growth factor 1

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

Igfbp7

insulin-like growth factor binding protein 7

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

Jag1

jagged canonical Notch ligand 1

involved_in

(MGI:3848573|PMID:19389353)

PMID:19389353

MGI:3848573

NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209

potassium voltage-gated channel subfamily Q member 1

involved_in

GO_REF:0000024
(MGI:1928449|PMID:11120752), (MGI:3056224|PMID:15498462)

PMID:11120752 PMID:15498462

GO_REF:0000024 MGI:1928449 MGI:3056224

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

Lgr5

leucine rich repeat containing G protein coupled receptor 5

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446

Lhx3

LIM homeobox 3

involved_in

(PMID:18407919)

PMID:18407919

NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480

Lin7a

lin-7 homolog A, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5140238|PMID:21795542)

GO_REF:0000107 MGI:5140238

NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550

Lrp10

LDL receptor related protein 10

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr15:27,921,105...27,927,507
Ensembl chr15:27,920,259...27,927,505

Maf

MAF bZIP transcription factor

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5140238|PMID:21795542)

GO_REF:0000107 MGI:5140238

NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365

Mapkapk2

MAPK activated protein kinase 2

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

Mnda

myeloid cell nuclear differentiation antigen

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

Mpv17

mitochondrial inner membrane protein MPV17

involved_in

(MGI:3776221|PMID:16041630)

PMID:16041630

MGI:3776221

NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244

Myo3a

myosin IIIA

acts_upstream_of_or_within

MGI:4849286 (MGI:4849846|PMID:21165622)

PMID:21165622

MGI:4849846

NCBI chr17:84,554,785...84,604,748
Ensembl chr17:84,543,552...84,759,042

Myo6

myosin VI

acts_upstream_of_or_within

MGI:1856555 (MGI:1346380|PMID:10525338), (MGI:53523|PMID:5980120), (MGI:77423|PMID:7493015)

PMID:5980120 PMID:7493015 PMID:10525338

MGI:1346380 MGI:53523 MGI:77423

NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292

myosin VIIA

acts_upstream_of_or_within

PMID:6627025 PMID:9435277 PMID:13336002 PMID:14198707

MGI:1197790 MGI:61338 MGI:63006 MGI:63018 MGI:76086

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

Neurod1

neuronal differentiation 1

involved_in

GO_REF:0000024
(MGI:1929186|PMID:11152640)

PMID:11152640

GO_REF:0000024 MGI:1929186

NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649

neurogenin 1

involved_in

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Nherf2

NHERF family PDZ scaffold protein 2

RGD

PMID:16160858

RGD:1643220

NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049

protocadherin related 15

acts_upstream_of_or_within

MGI:1855958|MGI:2151877|MGI:2183469 (MGI:1928787|PMID:10978835), (MGI:3574187|PMID:15811708)

PMID:10978835 PMID:15811708

MGI:1928787 MGI:3574187

NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719

Pdgfa

platelet derived growth factor subunit A

RGD

PMID:15267171

RGD:2292167

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

Pdgfra

platelet derived growth factor receptor alpha

RGD

PMID:15267171

RGD:2292167

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Pdgfrb

platelet derived growth factor receptor beta

RGD

PMID:15267171

RGD:2292167

NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843

Phox2b

paired-like homeobox 2b

acts_upstream_of_or_within

MGI:1926861 (MGI:3621705|PMID:12885554)

PMID:12885554

MGI:3621705

NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978

Plppr4

phospholipid phosphatase related 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5140238|PMID:21795542)

GO_REF:0000107 MGI:5140238

NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302

Pou3f4

POU class 3 homeobox 4

acts_upstream_of_or_within

MGI:1856631|MGI:1857990 (MGI:1351526|PMID:10587581), (MGI:3656465|PMID:15655183)

PMID:10587581 PMID:15655183

MGI:1351526 MGI:3656465

NCBI chr X:75,858,646...75,859,923
Ensembl chr X:75,858,646...75,859,923

POU class 4 homeobox 3

acts_upstream_of_or_within

MGI:1857425 (MGI:1095801|PMID:9256502), (MGI:1277883|PMID:9735355)

PMID:9256502 PMID:9735355

MGI:1095801 MGI:1277883

NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797

Prox1

prospero homeobox 1

acts_upstream_of_or_within

MGI:2386336 (MGI:4437346|PMID:20186345)

PMID:20186345

MGI:4437346

NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

involved_in

(PMID:12058348)

PMID:12058348

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Ror1

receptor tyrosine kinase-like orphan receptor 1

involved_in

(MGI:5776284|PMID:27162350)

PMID:27162350

MGI:5776284

NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155

RT1-A2

RT1 class Ia, locus A2

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr20:4,870,939...4,910,183

RT1-DMa

RT1 class II, locus DMa

acts_upstream_of_or_within

(MGI:5140238|PMID:21795542)

NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432

Shh

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1934261|MGI:95729 (MGI:3709667|PMID:17395647)

GO_REF:0000107 MGI:3709667

NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170

SIX homeobox 1

involved_in

(MGI:3848573|PMID:19389353)

PMID:19389353

MGI:3848573

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Slc25a27

solute carrier family 25, member 27

RGD

PMID:21397696

RGD:6482846

NCBI chr 9:17,306,898...17,333,942
Ensembl chr 9:17,307,023...17,332,731

Sox2

SRY-box transcription factor 2

involved_in

(PMID:18407919)

PMID:18407919

NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338

Sparc

secreted protein acidic and cysteine rich

RGD

PMID:11335086

RGD:2300061

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

Stox1

storkhead box 1

involved_in

(MGI:5635320|PMID:25677106)

PMID:25677106

MGI:5635320

NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939

Tgfb1

transforming growth factor, beta 1

RGD

PMID:16479080

RGD:2302094

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tgfb2

transforming growth factor, beta 2

involved_in

IEP
ISO

(MGI:894212|PMID:9217007)

PMID:9217007 PMID:16479080

MGI:894212, RGD:2302094

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tgfb3

transforming growth factor, beta 3

RGD

PMID:16479080

RGD:2302094

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

anterior semicircular canal development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gli3

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:3709667|PMID:17395647)

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

auditory receptor cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clrn1

clarin 1

acts_upstream_of_or_within

MGI:3850171 (MGI:3849925|PMID:19414487)

PMID:19414487

MGI:3849925

NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948

Fgfr1

Fibroblast growth factor receptor 1

acts_upstream_of_or_within

MGI:3574787 (MGI:3527944|PMID:15630379)

PMID:15630379

MGI:3527944

NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350

potassium voltage-gated channel subfamily Q member 1

involved_in

MGI:2680653 (MGI:5784951|PMID:26084842)
GO_REF:0000107

PMID:26084842

GO_REF:0000107 MGI:5784951

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

Lrtomt

leucine rich transmembrane and O-methyltransferase domain containing

involved_in

(MGI:3799635|PMID:18794526)

PMID:18794526

MGI:3799635

NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704

Pafah1b1

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

involved_in

(MGI:5477842|PMID:23533177)

PMID:23533177

MGI:5477842

NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808

Pdzd7

PDZ domain containing 7

acts_upstream_of_or_within

MGI:4433578 (MGI:5565635|PMID:24334608)

PMID:24334608

MGI:5565635

NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839

Slc4a7

solute carrier family 4 member 7

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:2682641 (MGI:2680888|PMID:12808454)

PMID:12808454 PMID:21873635

MGI:2680888, RGD:13792537

NCBI chr15:10,585,307...10,664,781
Ensembl chr15:10,588,979...10,664,781

Tmc1

transmembrane channel-like 1

acts_upstream_of_or_within

MGI:5427097 (MGI:5320864|PMID:22105175)

PMID:22105175

MGI:5320864

NCBI chr 1:218,275,262...218,445,955
Ensembl chr 1:218,276,417...218,445,955

auditory receptor cell fate commitment

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

delta like canonical Notch ligand 1

involved_in

NAS

PMID:10878608

UniProt

PMID:10878608

RGD:8553270

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

Jag2

jagged canonical Notch ligand 2

involved_in

ISS
ISO
IEA

PMID:10080181
(MGI:1332721|PMID:10080181)
GO_REF:0000107

PMID:10080181 PMID:10080181

GO_REF:0000107 MGI:1332721, RGD:8553713

NCBI chr 6:131,983,056...132,005,359
Ensembl chr 6:131,983,056...132,005,818

Notch1

notch receptor 1

acts_upstream_of_or_within

MGI:3044585|MGI:3046196 (MGI:3833041|PMID:19154718)

PMID:19154718

MGI:3833041

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

Rbpj

recombination signal binding protein for immunoglobulin kappa J region

acts_upstream_of_or_within

MGI:3046196|MGI:3583755 (MGI:3833041|PMID:19154718)

PMID:19154718

MGI:3833041

NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353

auditory receptor cell fate determination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

atonal bHLH transcription factor 1

acts_upstream_of_or_within

(MGI:3611666|PMID:16407553)

PMID:16407553

MGI:3611666

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

auditory receptor cell fate specification

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

atonal bHLH transcription factor 1

acts_upstream_of_or_within

MGI:2155983 (MGI:1339217|PMID:10364557)

PMID:10364557

MGI:1339217

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

auditory receptor cell morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mir96

microRNA 96

acts_upstream_of_or_within

MGI:4354110 (MGI:4353582|PMID:19363478)

PMID:19363478

MGI:4353582

NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516

Rac1

Rac family small GTPase 1

acts_upstream_of_or_within

MGI:2663662|MGI:2663669 (MGI:4430014|PMID:20016102)

PMID:20016102

MGI:4430014

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Scrib

scribble planar cell polarity protein

acts_upstream_of_or_within

MGI:2139764 (MGI:4439427|PMID:20215345)

NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331

Sec24b

SEC24 homolog B, COPII coat complex component

acts_upstream_of_or_within

MGI:2145950|MGI:4440621 (MGI:4439427|PMID:20215345)

NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699

Slitrk6

SLIT and NTRK-like family, member 6

acts_upstream_of_or_within

MGI:4417931 (MGI:4413621|PMID:19936227)

PMID:19936227

MGI:4413621

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

Wdpcp

WD repeat containing planar cell polarity effector

acts_upstream_of_or_within

MGI:5558098 (MGI:5544506|PMID:24302887)

PMID:24302887

MGI:5544506

NCBI chr14:95,645,955...95,977,120
Ensembl chr14:95,646,038...95,977,113

auditory receptor cell stereocilium organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1856799 (MGI:3709803|PMID:11875276)

PMID:11875276

MGI:3709803

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

cadherin-related 23

acts_upstream_of_or_within
involved_in

PMID:7610888 PMID:8790740 PMID:9039475 PMID:11138008 PMID:11322776 More...

GO_REF:0000107 MGI:1929001 MGI:1933915 MGI:3526751 MGI:3625226 MGI:3686545 MGI:5468200 MGI:75953 MGI:81497 MGI:86134

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

Clic5

chloride intracellular channel 5

acts_upstream_of_or_within

MGI:3663254 (MGI:3663248|PMID:17021174)

PMID:17021174

MGI:3663248

NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427

Clrn1

clarin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3850171 (MGI:3849925|PMID:19414487), (MGI:4353469|PMID:19423712)

PMID:19414487 PMID:19423712

GO_REF:0000107 MGI:3849925 MGI:4353469

NCBI chr 2:143,084,030...143,130,948
Ensembl chr 2:143,084,030...143,130,948

Clrn2

clarin 2

involved_in

(MGI:6810803|PMID:33496845)

PMID:33496845

MGI:6810803

NCBI chr14:65,656,550...65,666,193
Ensembl chr14:65,656,550...65,666,193

Grxcr2

glutaredoxin and cysteine rich domain containing 2

acts_upstream_of_or_within

MGI:2139535|MGI:6281113|MGI:6281114 (MGI:6278501|PMID:30380417)

PMID:30380417

MGI:6278501

NCBI chr18:33,984,689...33,998,094
Ensembl chr18:33,984,689...33,998,094

Lhfpl5

LHFPL tetraspan subfamily member 5

acts_upstream_of_or_within

MGI:3055797|MGI:3718054 (MGI:3578102|PMID:15905332), (MGI:3759710|PMID:17876667), (MGI:5468200|PMID:23217710)

PMID:15905332 PMID:17876667 PMID:23217710

MGI:3578102 MGI:3759710 MGI:5468200

NCBI chr20:6,632,362...6,642,534
Ensembl chr20:6,632,362...6,642,532

Myo3a

myosin IIIA

involved_in

MGI:2448580 (MGI:5766107|PMID:26754646)

NCBI chr17:84,554,785...84,604,748
Ensembl chr17:84,543,552...84,759,042

Myo3b

myosin IIIB

involved_in

MGI:2183924 (MGI:5766107|PMID:26754646)

NCBI chr 3:54,873,704...55,226,189
Ensembl chr 3:54,820,251...55,227,373

myosin VIIA

acts_upstream_of_or_within

MGI:1860092|MGI:2155422 (MGI:2156358|PMID:11753415), (MGI:3625226|PMID:12121736), (MGI:3686545|PMID:17050716)

PMID:11753415 PMID:12121736 PMID:17050716

MGI:2156358 MGI:3625226 MGI:3686545

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

Nherf1

NHERF family PDZ scaffold protein 1

acts_upstream_of_or_within

MGI:3526430 (MGI:5578076|PMID:24920589)

PMID:24920589

MGI:5578076

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

protocadherin related 15

acts_upstream_of_or_within

MGI:1855958|MGI:1856394|MGI:1856396|MGI:1890219|MGI:2151877|MGI:3505691 (MGI:1928787|PMID:10978835), (MGI:3526751|PMID:15537665), (MGI:3619110|PMID:11124469), (MGI:3654702|PMID:16887306), (MGI:5468200|PMID:23217710)

PMID:10978835 PMID:11124469 PMID:15537665 PMID:16887306 PMID:23217710

MGI:1928787 MGI:3526751 MGI:3619110 MGI:3654702 MGI:5468200

NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719

Pdzd7

PDZ domain containing 7

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:4433578 (MGI:5565635|PMID:24334608)

PMID:24334608 PMID:21873635

MGI:5565635, RGD:13792537

NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839

Pls1

plastin 1

involved_in

(MGI:5608770|PMID:25124451)

PMID:25124451

MGI:5608770

NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195

Rest

RE1-silencing transcription factor

involved_in

GO_REF:0000024
(MGI:6193260|PMID:29961578)

PMID:29961578

GO_REF:0000024 MGI:6193260

NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354

Ripor2

RHO family interacting cell polarization regulator 2

involved_in

(MGI:5789047|PMID:27269051)

PMID:27269051

MGI:5789047

NCBI chr17:40,323,867...40,547,482
Ensembl chr17:40,323,867...40,548,092

Scrib

scribble planar cell polarity protein

acts_upstream_of_or_within

MGI:2139764 (MGI:4439427|PMID:20215345)

NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331

Sec24b

SEC24 homolog B, COPII coat complex component

acts_upstream_of_or_within

MGI:2145950|MGI:4440621 (MGI:4439427|PMID:20215345)

PMID:10464373 PMID:10466888

NCBI chr 2:218,562,670...218,632,753
Ensembl chr 2:218,562,676...218,632,699

Sod1

superoxide dismutase 1

acts_upstream_of_or_within
involved_in

ISO
ISS

MGI:1857872 (MGI:1344578|PMID:10466888), (MGI:3700629|PMID:10464373)
GO_REF:0000024

RGD
UniProt

GO_REF:0000024 MGI:1344578 MGI:3700629

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

Strc

stereocilin

involved_in
acts_upstream_of_or_within

(MGI:5430850|PMID:21165971)
MGI:109575|MGI:3818633 (MGI:3818235|PMID:18849963), (MGI:6431964|PMID:30801007)

PMID:18849963 PMID:21165971 PMID:30801007

MGI:3818235 MGI:5430850 MGI:6431964

NCBI chr 3:108,335,920...108,355,114
Ensembl chr 3:108,335,747...108,354,134

Tecta

tectorin alpha

acts_upstream_of_or_within

MGI:2153816 (MGI:6431964|PMID:30801007)

PMID:30801007

MGI:6431964

NCBI chr 8:42,707,962...42,779,726
Ensembl chr 8:42,707,962...42,779,707

Tprn

taperin

acts_upstream_of_or_within
involved_in

MGI:2685697 (MGI:6278501|PMID:30380417)
PMID:21873635

PMID:30380417 PMID:21873635

MGI:6278501, RGD:13792537

NCBI chr 3:8,076,164...8,083,642
Ensembl chr 3:8,075,137...8,083,642

Triobp

TRIO and F-actin binding protein

acts_upstream_of_or_within

MGI:4881773 (MGI:4881391|PMID:20510926)

PMID:20510926

MGI:4881391

NCBI chr 7:110,505,916...110,569,301
Ensembl chr 7:110,506,248...110,562,474

Whrn

whirlin

involved_in
acts_upstream_of_or_within

IBA
ISO
IEA

PMID:21873635
MGI:4432119 (MGI:5796227|PMID:27117407)
GO_REF:0000107

PMID:27117407 PMID:21873635

GO_REF:0000107 MGI:5796227, RGD:13792537

NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223

cochlea development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adam10

ADAM metallopeptidase domain 10

involved_in

(MGI:6316556|PMID:30639848)

PMID:30639848

MGI:6316556

NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889

ATPase plasma membrane Ca2+ transporting 2

involved_in

(MGI:1275896|PMID:9668038)

PMID:9668038

MGI:1275896

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

calbindin 1

RGD

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

cyclin A2

RGD

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

Cdh1

cadherin 1

acts_upstream_of_or_within
involved_in

MGI:2389021|MGI:3841145 (MGI:5297632|PMID:21925491)
(MGI:6316556|PMID:30639848)

PMID:21925491 PMID:30639848

MGI:5297632 MGI:6316556

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

Cecr2

CECR2, histone acetyl-lysine reader

acts_upstream_of_or_within

MGI:3574034 (MGI:4880797|PMID:21246654)

PMID:21246654

MGI:4880797

NCBI chr 4:153,890,310...153,998,078
Ensembl chr 4:153,890,206...153,993,451

Dchs1

dachsous cadherin-related 1

acts_upstream_of_or_within

MGI:4867020 (MGI:4939936|PMID:21303848)

PMID:21303848

MGI:4939936

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

Epha4

Eph receptor A4

involved_in

(MGI:6316556|PMID:30639848)

PMID:30639848

MGI:6316556

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

fibroblast growth factor receptor 3

acts_upstream_of_or_within

MGI:1931521 (MGI:3714212|PMID:17557302)

PMID:17557302

MGI:3714212

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

Gabra5

gamma-aminobutyric acid type A receptor subunit alpha 5

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917

Gabrb2

gamma-aminobutyric acid type A receptor subunit beta 2

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

Gabrb3

gamma-aminobutyric acid type A receptor subunit beta 3

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

Gata2

GATA binding protein 2

RGD

PMID:20006695

RGD:9479067

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

Gata3

GATA binding protein 3

RGD

PMID:20006695

RGD:9479067

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

hes family bHLH transcription factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1341884|MGI:2149672 (MGI:3794221|PMID:18302773)

PMID:18302773

GO_REF:0000107 MGI:3794221

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

Hey2

hes-related family bHLH transcription factor with YRPW motif 2

acts_upstream_of_or_within

MGI:104853|MGI:104876|MGI:2447620 (MGI:3794221|PMID:18302773)

PMID:18302773

MGI:3794221

NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218

homeobox A1

involved_in

(PMID:16155570)

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

Ift20

intraflagellar transport 20

acts_upstream_of_or_within

MGI:3817268 (MGI:5615303|PMID:25605782)

NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124

Ift27

intraflagellar transport 27

acts_upstream_of_or_within

MGI:4461616 (MGI:5615303|PMID:25605782)

NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416

Ift88

intraflagellar transport 88

acts_upstream_of_or_within

MGI:2135272 (MGI:3773480|PMID:18066062)

PMID:18066062

MGI:3773480

NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147

Kcnk2

potassium two pore domain channel subfamily K member 2

RGD

PMID:15094499

RGD:2316534

NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435

Kcnk3

potassium two pore domain channel subfamily K member 3

RGD

PMID:15094499

RGD:2316534

NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153

potassium voltage-gated channel subfamily Q member 1

involved_in

MGI:1931858 (MGI:3641254|PMID:15891643)
GO_REF:0000107

PMID:15891643

GO_REF:0000107 MGI:3641254

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

Mcm2

minichromosome maintenance complex component 2

involved_in

(PMID:26196677)

PMID:26196677

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

Musk

muscle associated receptor tyrosine kinase

RGD

PMID:18420419

RGD:2317082

NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932

neurogenin 1

involved_in

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Ntrk3

neurotrophic receptor tyrosine kinase 3

RGD

PMID:10494076

RGD:2325650

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

oncomodulin

RGD

NCBI chr12:10,535,619...10,596,705
Ensembl chr12:10,586,897...10,596,707

Opa1

OPA1, mitochondrial dynamin like GTPase

RGD

PMID:17828551

RGD:13208944

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

otoferlin

RGD

NCBI chr 6:25,928,018...26,024,631
Ensembl chr 6:25,928,055...26,024,631

Pafah1b1

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

involved_in

(MGI:5477842|PMID:23533177)

PMID:23533177

MGI:5477842

NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808

Pax2

paired box 2

involved_in

GO_REF:0000024
(MGI:84247|PMID:8951055)

PMID:8951055

GO_REF:0000024 MGI:84247

NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321

Psap

prosaposin

acts_upstream_of_or_within

MGI:1888378 (MGI:3694123|PMID:17167097)

PMID:17167097

MGI:3694123

NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498

parvalbumin

RGD

NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561

Rpgrip1l

Rpgrip1-like

acts_upstream_of_or_within

MGI:3716208 (MGI:5449641|PMID:22927466)

PMID:22927466

MGI:5449641

NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083

Slc17a8

solute carrier family 17 member 8

RGD

PMID:24064385

RGD:9999152

NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079

Slc26a5

solute carrier family 26 member 5

RGD

PMID:20006695

RGD:9479067

NCBI chr 4:13,210,260...13,249,289
Ensembl chr 4:13,210,260...13,249,289

Slitrk6

SLIT and NTRK-like family, member 6

acts_upstream_of_or_within

MGI:4417931 (MGI:4413621|PMID:19936227)

PMID:19936227

MGI:4413621

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

Sobp

sine oculis binding protein homolog

involved_in

(MGI:3801556|PMID:18579736)

PMID:18579736

MGI:3801556

NCBI chr20:46,482,265...46,661,452
Ensembl chr20:46,482,765...46,663,541

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

MGI:98715 (MGI:3773480|PMID:18066062)

PMID:18066062

MGI:3773480

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

cochlea morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cthrc1

collagen triple helix repeat containing 1

acts_upstream_of_or_within

MGI:1915838 (MGI:3814781|PMID:18606138)

PMID:18606138

MGI:3814781

NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756

Dvl1

dishevelled segment polarity protein 1

acts_upstream_of_or_within

MGI:106613 (MGI:3589836|PMID:16116426)

PMID:16116426

MGI:3589836

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

Dvl2

dishevelled segment polarity protein 2

acts_upstream_of_or_within

MGI:108100|MGI:94941 (MGI:3589836|PMID:16116426), (MGI:3821448|PMID:19008950)

PMID:16116426 PMID:19008950

MGI:3589836 MGI:3821448

NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820

Dvl3

dishevelled segment polarity protein 3

acts_upstream_of_or_within

MGI:106613|MGI:2135272 (MGI:3821448|PMID:19008950)

PMID:19008950

MGI:3821448

NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

MGI:1857803 (MGI:1335261|PMID:10072433)

PMID:10072433

MGI:1335261

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

Frzb

frizzled-related protein

acts_upstream_of_or_within

MGI:98958 (MGI:3714704|PMID:17433286)

PMID:17433286

MGI:3714704

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

Fzd2

frizzled class receptor 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2135272 (MGI:4837757|PMID:20940229)

PMID:20940229

GO_REF:0000107 MGI:4837757

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

Gli2

GLI family zinc finger 2

acts_upstream_of_or_within

MGI:1857509 (MGI:3709667|PMID:17395647)

NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574

Grhl3

grainyhead-like transcription factor 3

acts_upstream_of_or_within

MGI:2135272 (MGI:4819429|PMID:20643356)

PMID:20643356

MGI:4819429

NCBI chr 5:147,774,160...147,806,338
Ensembl chr 5:147,774,160...147,806,160

homeobox A1

involved_in

(PMID:16155570)

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

Hpn

hepsin

involved_in

GO_REF:0000024
(MGI:5306554|PMID:20683358)

PMID:20683358

GO_REF:0000024 MGI:5306554

NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811

Myo3a

myosin IIIA

involved_in

(MGI:5766107|PMID:26754646)

NCBI chr17:84,554,785...84,604,748
Ensembl chr17:84,543,552...84,759,042

Myo3b

myosin IIIB

involved_in

(MGI:5766107|PMID:26754646)

NCBI chr 3:54,873,704...55,226,189
Ensembl chr 3:54,820,251...55,227,373

neurogenin 1

involved_in

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Pax2

paired box 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:1857673 (MGI:3702803|PMID:16916509)
UniProtKB:Q00288 (MGI:4822275|PMID:20727173), (MGI:84247|PMID:8951055)

PMID:8951055 PMID:16916509 PMID:20727173

GO_REF:0000024 MGI:3702803 MGI:4822275 MGI:84247

NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321

Pou3f4

POU class 3 homeobox 4

involved_in

GO_REF:0000024
UniProtKB:P70323 (MGI:5284768|PMID:18231833)

PMID:18231833

GO_REF:0000024 MGI:5284768

NCBI chr X:75,858,646...75,859,923
Ensembl chr X:75,858,646...75,859,923

Ptk7

protein tyrosine kinase 7

acts_upstream_of_or_within

MGI:3640803 (MGI:4830023|PMID:20704721)

PMID:20704721

MGI:4830023

NCBI chr 9:14,352,155...14,418,494
Ensembl chr 9:14,351,202...14,418,494

Rac1

Rac family small GTPase 1

acts_upstream_of_or_within

MGI:2663662|MGI:2663669 (MGI:4430014|PMID:20016102)

PMID:20016102

MGI:4430014

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

SIX homeobox 1

acts_upstream_of_or_within

MGI:2655195 (MGI:2671031|PMID:12874121)

PMID:12874121

MGI:2671031

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Sox9

SRY-box transcription factor 9

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2385468|MGI:3841145 (MGI:4454502|PMID:20346939)

PMID:20346939

GO_REF:0000024 MGI:4454502

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

T-box transcription factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2179136 (MGI:3765363|PMID:17825816)
UniProtKB:P62515 (MGI:5284768|PMID:18231833)

PMID:17825816 PMID:18231833

GO_REF:0000024 MGI:3765363 MGI:5284768

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

Tbx18

T-box transcription factor 18

acts_upstream_of_or_within

MGI:3044915 (MGI:3788971|PMID:18353863)

PMID:18353863

MGI:3788971

NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058

Tbx2

T-box transcription factor 2

involved_in

(MGI:6710296|PMID:33795231)

PMID:33795231

MGI:6710296

NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

Tshr

thyroid stimulating hormone receptor

acts_upstream_of_or_within

(MGI:3652455|PMID:10575115)

PMID:10575115

MGI:3652455

NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

MGI:3589836 MGI:3714704 MGI:3814781 MGI:3821448 MGI:4819429 MGI:4837757

PMID:16116426 PMID:17433286 PMID:18606138 PMID:19008950 PMID:20643356 More...

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

Wnt5a

Wnt family member 5A

acts_upstream_of_or_within

MGI:1857617|MGI:2135272 (MGI:3714704|PMID:17433286)

PMID:17433286

MGI:3714704

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

Zeb1

zinc finger E-box binding homeobox 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1861230 (MGI:5294688|PMID:21980308)

PMID:21980308

GO_REF:0000107 MGI:5294688

NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214

inner ear auditory receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

atonal bHLH transcription factor 1

acts_upstream_of_or_within

MGI:2155983|MGI:2155984 (MGI:2178088|PMID:11973280), (MGI:3525036|PMID:15543141)
(MGI:3833041|PMID:19154718)

PMID:11973280 PMID:15543141 PMID:19154718

MGI:2178088 MGI:3525036 MGI:3833041

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

Bmp4

bone morphogenetic protein 4

acts_upstream_of_or_within
involved_in

MGI:95524 (MGI:3714221|PMID:17555714)
GO_REF:0000107

PMID:17555714

GO_REF:0000107 MGI:3714221

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

cadherin-related 23

acts_upstream_of_or_within

MGI:1856228 (MGI:3625226|PMID:12121736)

PMID:12121736

MGI:3625226

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

Clrn2

clarin 2

acts_upstream_of_or_within

MGI:5792002|MGI:6458758 (MGI:6376373|PMID:31448880)

PMID:31448880

MGI:6376373

NCBI chr14:65,656,550...65,666,193
Ensembl chr14:65,656,550...65,666,193

Cux1

cut-like homeobox 1

acts_upstream_of_or_within

MGI:2388352 (MGI:2149924|PMID:11544187)

PMID:11544187

MGI:2149924

NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866

delta like canonical Notch ligand 1

acts_upstream_of
involved_in

MGI:1932522|MGI:3044907 (MGI:3621102|PMID:16495313)
GO_REF:0000107

PMID:16495313

GO_REF:0000107 MGI:3621102

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

Fgf2

fibroblast growth factor 2

acts_upstream_of

(MGI:2429373|PMID:12417662)

PMID:12417662

MGI:2429373

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

Fgf20

fibroblast growth factor 20

acts_upstream_of_or_within

(MGI:3798124|PMID:18524904)

PMID:18524904

MGI:3798124

NCBI chr16:52,030,853...52,037,612
Ensembl chr16:52,010,194...52,038,204

fibroblast growth factor receptor 3

acts_upstream_of_or_within

PMID:17117437 PMID:17555714 PMID:17557302

MGI:3695846 MGI:3714212 MGI:3714221

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

Gfi1

growth factor independent 1 transcriptional repressor

acts_upstream_of_or_within

MGI:2449921 (MGI:2429425|PMID:12441305)

PMID:12441305

MGI:2429425

NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814

glutaredoxin and cysteine rich domain containing 1

acts_upstream_of_or_within

MGI:2681910 (MGI:2680830|PMID:12405956)

PMID:12405956

MGI:2680830

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

Gsdme

gasdermin E

acts_upstream_of_or_within

MGI:3583715 (MGI:3583372|PMID:16023581)

PMID:16023581

MGI:3583372

NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806

hes family bHLH transcription factor 1

acts_upstream_of
involved_in

MGI:104876|MGI:1341800 (MGI:4949990|PMID:21300049)
GO_REF:0000107

GO_REF:0000107 MGI:4949990

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

hes family bHLH transcription factor 5

acts_upstream_of

MGI:104853|MGI:1341800 (MGI:4949990|PMID:21300049)

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

Jag1

jagged canonical Notch ligand 1

acts_upstream_of_or_within
involved_in

IMP
ISO
IEA

MGI:1932522|MGI:3623344 (MGI:3621102|PMID:16495313)
GO_REF:0000107

PMID:16495313 PMID:10887092

GO_REF:0000107 MGI:3621102, RGD:1582345

NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209

Kcnma1

potassium calcium-activated channel subfamily M alpha 1

acts_upstream_of_or_within

MGI:3050114 (MGI:3052624|PMID:15328414), (MGI:3697555|PMID:17074442)

PMID:15328414 PMID:17074442

MGI:3052624 MGI:3697555

NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198

Mcoln3

mucolipin TRP cation channel 3

acts_upstream_of_or_within

MGI:1856230 (MGI:2445676|PMID:12403827)

PMID:12403827

MGI:2445676

NCBI chr 2:234,966,010...235,043,047
Ensembl chr 2:234,966,010...235,043,047

Myo6

myosin VI

acts_upstream_of_or_within
involved_in

MGI:1856555 (MGI:1346380|PMID:10525338), (MGI:53523|PMID:5980120), (MGI:77423|PMID:7493015)
PMID:21873635

PMID:5980120 PMID:7493015 PMID:10525338 PMID:21873635

MGI:1346380 MGI:53523 MGI:77423, RGD:13792537

NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292

myosin VIIA

acts_upstream_of_or_within

PMID:11753415 PMID:12121736 PMID:15389316

MGI:2156358 MGI:3510503 MGI:3625226

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

protocadherin related 15

acts_upstream_of_or_within

MGI:1856394 (MGI:3616414|PMID:16481439)

PMID:16481439

MGI:3616414

NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719

plastin 3

RGD

NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891

POU class 4 homeobox 3

acts_upstream_of_or_within

MGI:1857425|MGI:2176270 (MGI:2451279|PMID:12585968), (MGI:80981|PMID:8637595)

PMID:8637595 PMID:12585968

MGI:2451279 MGI:80981

NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797

Ush1c

USH1 protein network component harmonin

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:2651858|MGI:2651859 (MGI:2675093|PMID:14519688)

PMID:14519688 PMID:21873635

MGI:2675093, RGD:13792537

NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671

Ush2a

usherin

acts_upstream_of_or_within
involved_in

MGI:3702040 (MGI:3700725|PMID:17360538)
GO_REF:0000107

PMID:17360538

GO_REF:0000107 MGI:3700725

NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922

inner ear morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abr

ABR activator of RhoGEF and GTPase

acts_upstream_of_or_within

MGI:88141 (MGI:3622851|PMID:11921339)

PMID:11921339

MGI:3622851

NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505

Aldh1a3

aldehyde dehydrogenase 1 family, member A3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3043947 (MGI:5488831|PMID:23536097)

PMID:23536097

GO_REF:0000107 MGI:5488831

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

atonal bHLH transcription factor 1

acts_upstream_of_or_within

MGI:2155983|MGI:2155984 (MGI:3525036|PMID:15543141), (MGI:3607238|PMID:16145671)

PMID:15543141 PMID:16145671

MGI:3525036 MGI:3607238

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1857876 (MGI:1275896|PMID:9668038)

PMID:9668038

MGI:1275896

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

Atp6v1b1

ATPase H+ transporting V1 subunit B1

involved_in
NOT|involved_in

GO_REF:0000024
(MGI:2669353|PMID:12782355)
(PMID:19639346)

PMID:12782355 PMID:19639346

GO_REF:0000024 MGI:2669353

NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475

Atp8a2

ATPase phospholipid transporting 8A2

involved_in

(MGI:5574432|PMID:24413176)

PMID:24413176

MGI:5574432

NCBI chr15:33,817,309...34,350,193
Ensembl chr15:33,819,755...34,350,223

Bcr

BCR activator of RhoGEF and GTPase

acts_upstream_of_or_within

MGI:107771 (MGI:3622851|PMID:11921339)

PMID:11921339

MGI:3622851

NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016

cadherin-related 23

acts_upstream_of_or_within

MGI:1856229|MGI:1856681|MGI:2665714 (MGI:3579755|PMID:15925194), (MGI:75953|PMID:7610888)

PMID:7610888 PMID:15925194

MGI:3579755 MGI:61210 MGI:75953

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

Celsr1

cadherin, EGF LAG seven-pass G-type receptor 1

acts_upstream_of_or_within

MGI:1862019|MGI:2668337 (MGI:2667273|PMID:12842012)

PMID:12842012

MGI:2667273

NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164

Chd7

chromodomain helicase DNA binding protein 7

involved_in
acts_upstream_of_or_within

(PMID:15300250)
PMID:21873635
MGI:3511552 (MGI:3056111|PMID:15353999)

PMID:15300250 PMID:15353999 PMID:21873635

MGI:3056111, RGD:13792537

NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358

Chrna10

cholinergic receptor nicotinic alpha 10 subunit

acts_upstream_of_or_within

MGI:3774038 (MGI:3771935|PMID:18077337)

PMID:18077337

MGI:3771935

NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476

Chrna9

cholinergic receptor nicotinic alpha 9 subunit

acts_upstream_of_or_within

MGI:2158742 (MGI:3771935|PMID:18077337)

PMID:18077337

MGI:3771935

NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192

Col11a1

collagen type XI alpha 1 chain

acts_upstream_of_or_within

MGI:1856399 (MGI:49531|PMID:1952599)

PMID:1952599

MGI:49531

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

Col2a1

collagen type II alpha 1 chain

acts_upstream_of_or_within

MGI:1857275 (MGI:892501|PMID:9165353)

PMID:9165353

MGI:892501

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Dlx5

distal-less homeobox 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:101927|MGI:2180474 (MGI:2384365|PMID:12142028), (MGI:3689133|PMID:16900517)

PMID:12142028 PMID:16900517

GO_REF:0000107 MGI:2384365 MGI:3689133

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

Dlx6

distal-less homeobox 6

acts_upstream_of_or_within

MGI:101926 (MGI:3689133|PMID:16900517)

PMID:16900517

MGI:3689133

NCBI chr 4:34,984,264...34,989,926
Ensembl chr 4:34,984,232...34,991,343

ephrin A2

RGD

NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061

Ephb2

Eph receptor B2

involved_in

(MGI:1859095|PMID:10839360)

PMID:10839360

MGI:1859095

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

PMID:10471511 PMID:15817220 PMID:16916509

MGI:1344210 MGI:3577160 MGI:3702803

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

fibroblast growth factor 10

acts_upstream_of_or_within

MGI:1347464|MGI:1859647 (MGI:3654570|PMID:16691564), (MGI:3688470|PMID:11062007)

PMID:11062007 PMID:16691564

MGI:3654570 MGI:3688470

NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866

Fgf8

fibroblast growth factor 8

acts_upstream_of_or_within

MGI:1345138 (MGI:3577817|PMID:15809037)

PMID:15809037

MGI:3577817

NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359

Fgf9

fibroblast growth factor 9

acts_upstream_of_or_within

MGI:2135961 (MGI:3056034|PMID:15328018)

PMID:15328018

MGI:3056034

NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309

Fgfr1

Fibroblast growth factor receptor 1

acts_upstream_of_or_within

MGI:2153351 (MGI:2386422|PMID:12194867)

PMID:12194867

MGI:2386422

NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350

Fgfr2

fibroblast growth factor receptor 2

acts_upstream_of_or_within

MGI:2153811 (MGI:2153190|PMID:10934262)

PMID:10934262

MGI:2153190

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

Foxg1

forkhead box G1

acts_upstream_of_or_within

MGI:1099809|MGI:2388671 (MGI:3654570|PMID:16691564)

PMID:16691564

MGI:3654570

NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607

Foxi1

forkhead box I1

acts_upstream_of_or_within

MGI:2448634 (MGI:2652196|PMID:12642503)

PMID:12642503

MGI:2652196

NCBI chr10:18,806,292...18,810,231
Ensembl chr10:18,806,308...18,810,231

Frzb

frizzled-related protein

acts_upstream_of_or_within

MGI:98958 (MGI:3823145|PMID:18991062)

PMID:18991062

MGI:3823145

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

Fzd3

frizzled class receptor 3

acts_upstream_of_or_within

MGI:108474 (MGI:3616416|PMID:16495441)

PMID:16495441

MGI:3616416

NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369

Fzd6

frizzled class receptor 6

acts_upstream_of_or_within

MGI:108476 (MGI:3616416|PMID:16495441)

PMID:16495441

MGI:3616416

NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776

Gata2

GATA binding protein 2

acts_upstream_of_or_within

MGI:4818492 (MGI:4821520|PMID:20652952)

PMID:20652952

MGI:4821520

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

Gata3

GATA binding protein 3

acts_upstream_of_or_within

MGI:2153826|MGI:2181200 (MGI:1928163|PMID:11135239), (MGI:5013488|PMID:21553382)

PMID:11135239 PMID:21553382

MGI:1928163 MGI:5013488

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

Gbx2

gastrulation brain homeobox 2

acts_upstream_of_or_within

MGI:1857634 (MGI:3578572|PMID:15829521), (MGI:3588904|PMID:15996652)

PMID:15829521 PMID:15996652

MGI:3578572 MGI:3588904

NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212

Gfi1

growth factor independent 1 transcriptional repressor

acts_upstream_of_or_within

MGI:2449921 (MGI:2429425|PMID:12441305)

PMID:12441305

MGI:2429425

NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814

Hmx2

H6 family homeobox 2

acts_upstream_of_or_within

MGI:107160|MGI:2154542 (MGI:2154463|PMID:11748138), (MGI:3055237|PMID:15363417)

PMID:11748138 PMID:15363417

MGI:2154463 MGI:3055237

NCBI chr 1:186,319,110...186,326,771
Ensembl chr 1:186,319,110...186,326,771

Hmx3

H6 family homeobox 3

acts_upstream_of_or_within

MGI:107159|MGI:1857577 (MGI:1197796|PMID:9435283), (MGI:3055237|PMID:15363417)

PMID:9435283 PMID:15363417

MGI:1197796 MGI:3055237

NCBI chr 1:186,313,237...186,315,201
Ensembl chr 1:186,313,063...186,315,201

homeobox A1

acts_upstream_of_or_within

MGI:3056069 (MGI:3055618|PMID:15367676)

PMID:15367676

MGI:3055618

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

Insig1

insulin induced gene 1

acts_upstream_of_or_within

MGI:1920249 (MGI:3689278|PMID:16955138)

PMID:16955138

MGI:3689278

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

Insig2

insulin induced gene 2

acts_upstream_of_or_within

MGI:1916289 (MGI:3689278|PMID:16955138)

PMID:16955138

MGI:3689278

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

Itga8

integrin subunit alpha 8

acts_upstream_of_or_within

MGI:2181699 (MGI:1355040|PMID:10742111)

PMID:10742111

MGI:1355040

NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510

potassium voltage-gated channel subfamily Q member 1

involved_in

MGI:2680653 (MGI:1931646|PMID:11226272)
GO_REF:0000107

PMID:11226272

GO_REF:0000107 MGI:1931646

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

Kcnq4

potassium voltage-gated channel subfamily Q member 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3618993 (MGI:3617033|PMID:16437162)

PMID:16437162

GO_REF:0000107 MGI:3617033

NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932

Mafb

MAF bZIP transcription factor B

acts_upstream_of_or_within

MGI:1856419 (MGI:3611672|PMID:16325169)

PMID:16325169

MGI:3611672

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

Myo15a

myosin XVA

acts_upstream_of_or_within

MGI:1857036 (MGI:3041655|PMID:14724386), (MGI:3054106|PMID:11718241)

PMID:11718241 PMID:14724386

MGI:3041655 MGI:3054106

NCBI chr10:45,277,619...45,335,953
Ensembl chr10:45,278,737...45,335,340

Myo6

myosin VI

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1856555 (MGI:77423|PMID:7493015)

PMID:7493015 PMID:21873635

MGI:77423, RGD:13792537

NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292

myosin VIIA

acts_upstream_of_or_within

MGI:1856716|MGI:1860092|MGI:2155422|MGI:3511858 (MGI:2156358|PMID:11753415), (MGI:3510503|PMID:15389316), (MGI:53596|PMID:5795329)

PMID:5795329 PMID:11753415 PMID:15389316

MGI:2156358 MGI:3510503 MGI:53596

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

neurogenin 1

involved_in
acts_upstream_of_or_within

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)
MGI:2183171 (MGI:3607238|PMID:16145671)

PMID:16145671 PMID:23419067

MGI:3607238

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Nr4a3

nuclear receptor subfamily 4, group A, member 3

acts_upstream_of_or_within

MGI:3037444 (MGI:2157256|PMID:11784868)

PMID:11784868

MGI:2157256

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

Ntn1

netrin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2137018 (MGI:3718276|PMID:17616930)

PMID:17616930

GO_REF:0000107 MGI:3718276

NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326

Otop1

otopetrin 1

acts_upstream_of_or_within
involved_in

MGI:1856638|MGI:2655558 (MGI:2654297|PMID:12651873)
PMID:21873635

PMID:12651873 PMID:21873635

MGI:2654297, RGD:13792537

NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497

Otx1

orthodenticle homeobox 1

acts_upstream_of_or_within

MGI:2136272|MGI:97451 (MGI:1335816|PMID:10225993)

PMID:10225993

MGI:1335816

NCBI chr14:96,082,151...96,089,161
Ensembl chr14:96,082,151...96,089,086

Otx2

orthodenticle homeobox 2

acts_upstream_of_or_within

MGI:97450 (MGI:1335816|PMID:10225993)

PMID:10225993

MGI:1335816

NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416

Pax2

paired box 2

involved_in
acts_upstream_of_or_within

PMID:8951055 PMID:15242798 PMID:16916509 PMID:20727173

GO_REF:0000024 MGI:3052393 MGI:3702803 MGI:4822275 MGI:84247

NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321

Pax8

paired box 8

involved_in

UniProtKB:P32114 (MGI:4822275|PMID:20727173)

PMID:20727173

MGI:4822275

NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363

POU class 4 homeobox 3

acts_upstream_of_or_within

MGI:1857425 (MGI:2451279|PMID:12585968)

PMID:12585968

MGI:2451279

NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797

Prrx1

paired related homeobox 1

acts_upstream_of_or_within

MGI:98218 (MGI:1306737|PMID:9729491)

PMID:9729491

MGI:1306737

NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866

Prrx2

paired related homeobox 2

acts_upstream_of_or_within

MGI:97712 (MGI:1306737|PMID:9729491)

PMID:9729491

MGI:1306737

NCBI chr 3:14,132,511...14,168,535
Ensembl chr 3:14,094,004...14,168,535

Ptprq

protein tyrosine phosphatase, receptor type, Q

acts_upstream_of_or_within

MGI:2679316 (MGI:2677560|PMID:14534255)

PMID:14534255

MGI:2677560

NCBI chr 7:42,837,109...43,016,917
Ensembl chr 7:42,837,109...43,016,917

Ror2

receptor tyrosine kinase-like orphan receptor 2

acts_upstream_of_or_within

MGI:2183225 (MGI:3814781|PMID:18606138)

PMID:18606138

MGI:3814781

NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152

SIX homeobox 1

acts_upstream_of_or_within

MGI:106034 (MGI:3578604|PMID:15788460)

PMID:15788460

MGI:3578604

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Six4

SIX homeobox 4

acts_upstream_of_or_within

MGI:102780 (MGI:3578604|PMID:15788460)

PMID:15788460

MGI:3578604

NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992

Slitrk6

SLIT and NTRK-like family, member 6

acts_upstream_of_or_within

MGI:4417931 (MGI:4413621|PMID:19936227)

PMID:19936227

MGI:4413621

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

Sobp

sine oculis binding protein homolog

acts_upstream_of_or_within
involved_in

MGI:1856614 (MGI:3664354|PMID:16962269)
PMID:21873635

PMID:16962269 PMID:21873635

MGI:3664354, RGD:13792537

NCBI chr20:46,482,265...46,661,452
Ensembl chr20:46,482,765...46,663,541

Sox2

SRY-box transcription factor 2

acts_upstream_of_or_within

MGI:2447995 (MGI:3578496|PMID:15846349)

PMID:15846349

MGI:3578496

NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338

Spry2

sprouty RTK signaling antagonist 2

acts_upstream_of_or_within

MGI:3578633|MGI:99604 (MGI:3577817|PMID:15809037)

PMID:15809037

MGI:3577817

NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009

T-box transcription factor 1

involved_in
acts_upstream_of_or_within

PMID:12913075 PMID:15084464 PMID:15652707 PMID:16600992

GO_REF:0000024 MGI:2671642 MGI:3039048 MGI:3530686 MGI:3629255

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

Tbx3

T-box transcription factor 3

involved_in

UniProtKB:Q60707 (MGI:6710296|PMID:33795231)

PMID:33795231

MGI:6710296

NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708

Tfap2a

transcription factor AP-2 alpha

involved_in

GO_REF:0000024
(PMID:21204207)

PMID:21204207

GO_REF:0000024

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

Tmie

transmembrane inner ear

acts_upstream_of_or_within
involved_in

MGI:1857053 (MGI:2183496|PMID:12140191)
PMID:21873635

PMID:12140191 PMID:21873635

MGI:2183496, RGD:13792537

NCBI chr 8:110,849,713...110,864,803
Ensembl chr 8:110,850,034...110,864,803

Ush1c

USH1 protein network component harmonin

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:2651858|MGI:2651859 (MGI:2675093|PMID:14519688)

PMID:14519688 PMID:21873635

MGI:2675093, RGD:13792537

NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671

Ush1g

USH1 protein network component sans

acts_upstream_of_or_within

MGI:2450561 (MGI:2450572|PMID:12588793), (MGI:49706|PMID:1927362)

PMID:1927362 PMID:12588793

MGI:2450572 MGI:49706

NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590

Wnt1

Wnt family member 1

acts_upstream_of_or_within

MGI:98956 (MGI:3582112|PMID:15961523)

PMID:15961523

MGI:3582112

NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651

Wnt3a

Wnt family member 3A

acts_upstream_of_or_within

MGI:98953 (MGI:3582112|PMID:15961523)

PMID:15961523

MGI:3582112

NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324

Wnt5a

Wnt family member 5A

acts_upstream_of_or_within

(MGI:3823145|PMID:18991062)

PMID:18991062

MGI:3823145

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

inner ear receptor cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atp8b1

ATPase phospholipid transporting 8B1

involved_in

(MGI:3849653|PMID:19478059)

PMID:19478059

MGI:3849653

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

Dicer1

dicer 1 ribonuclease III

acts_upstream_of_or_within

MGI:3589208 (MGI:3844748|PMID:19416898)

PMID:19416898

MGI:3844748

NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965

Fzd2

frizzled class receptor 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2135272 (MGI:4837757|PMID:20940229)

PMID:20940229

GO_REF:0000107 MGI:4837757

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

Gabra5

gamma-aminobutyric acid type A receptor subunit alpha 5

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917

Gabrb2

gamma-aminobutyric acid type A receptor subunit beta 2

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

Gabrb3

gamma-aminobutyric acid type A receptor subunit beta 3

involved_in

(MGI:3664129|PMID:17021187)

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

glutaredoxin and cysteine rich domain containing 1

involved_in

(MGI:3512691|PMID:11276175)

PMID:11276175

MGI:3512691

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

Naglu

N-acetyl-alpha-glucosaminidase

acts_upstream_of_or_within

MGI:1934018 (MGI:3769195|PMID:17712420)

PMID:17712420

MGI:3769195

NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972

Tshr

thyroid stimulating hormone receptor

acts_upstream_of_or_within

MGI:1856914 (MGI:3652455|PMID:10575115)

PMID:10575115

MGI:3652455

NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

MGI:1888513 (MGI:4837757|PMID:20940229)

PMID:20940229

MGI:4837757

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

inner ear receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1856799 (MGI:3709803|PMID:11875276)

PMID:11875276

MGI:3709803

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

myosin VIIA

acts_upstream_of_or_within

MGI:1856716|MGI:1860092|MGI:2155417|MGI:2155420|MGI:2155421|MGI:2155422|MGI:2155423 (MGI:1197790|PMID:9435277), (MGI:1289591|PMID:9680294)

PMID:9435277 PMID:9680294

MGI:1197790 MGI:1289591

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

POU class 4 homeobox 3

acts_upstream_of_or_within

MGI:1857425 (MGI:1095801|PMID:9256502), (MGI:1277883|PMID:9735355)

PMID:9256502 PMID:9735355

MGI:1095801 MGI:1277883

NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797

Ush1g

USH1 protein network component sans

acts_upstream_of_or_within

PMID:1442008 PMID:1763621 PMID:1927362 PMID:12588793

MGI:2450572 MGI:49706 MGI:50720 MGI:59980

NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590

inner ear receptor cell stereocilium organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adgrv1

adhesion G protein-coupled receptor V1

acts_upstream_of_or_within

MGI:3718538 (MGI:3718182|PMID:17295842)
MGI:3527179 (MGI:3714249|PMID:17567809)

PMID:17295842 PMID:17567809

MGI:3714249 MGI:3718182

NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688

Alms1

ALMS1, centrosome and basal body associated protein

acts_upstream_of_or_within

MGI:3576051 (MGI:4867594|PMID:21071598)

PMID:21071598

MGI:4867594

NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005

cadherin-related 23

acts_upstream_of_or_within

MGI:2154548 (MGI:3794916|PMID:18339676)

NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419

Cecr2

CECR2, histone acetyl-lysine reader

acts_upstream_of_or_within

MGI:3574034|MGI:4829945 (MGI:4880797|PMID:21246654)

PMID:21246654

MGI:4880797

NCBI chr 4:153,890,310...153,998,078
Ensembl chr 4:153,890,206...153,993,451

Cthrc1

collagen triple helix repeat containing 1

acts_upstream_of_or_within

MGI:1915838 (MGI:3814781|PMID:18606138)

PMID:18606138

MGI:3814781

NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756

Fat4

FAT atypical cadherin 4

acts_upstream_of_or_within

MGI:3846573 (MGI:4939936|PMID:21303848)

PMID:21303848

MGI:4939936

NCBI chr 2:121,928,188...122,056,711
Ensembl chr 2:121,927,942...122,056,707

glutaredoxin and cysteine rich domain containing 1

involved_in

PMID:21873635
(MGI:4421424|PMID:20137774)

PMID:20137774 PMID:21873635

MGI:4421424, RGD:13792537

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

Grxcr2

glutaredoxin and cysteine rich domain containing 2

acts_upstream_of_or_within

MGI:6281113|MGI:6281114 (MGI:6278501|PMID:30380417)

PMID:30380417

MGI:6278501

NCBI chr18:33,984,689...33,998,094
Ensembl chr18:33,984,689...33,998,094

hes family bHLH transcription factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:104876|MGI:1341800 (MGI:4949990|PMID:21300049)

GO_REF:0000107 MGI:4949990

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

hes family bHLH transcription factor 5

acts_upstream_of_or_within

MGI:104853|MGI:1341800 (MGI:4949990|PMID:21300049)

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

Hey1

hes-related family bHLH transcription factor with YRPW motif 1

acts_upstream_of_or_within

MGI:104853|MGI:104876 (MGI:4949990|PMID:21300049)

NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312

Ift20

intraflagellar transport 20

acts_upstream_of_or_within

MGI:3817268 (MGI:5615303|PMID:25605782)

NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124

Ift27

intraflagellar transport 27

acts_upstream_of_or_within

MGI:4461616 (MGI:5615303|PMID:25605782)

NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416

Ift88

intraflagellar transport 88

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1932522|MGI:2135272|MGI:3710185 (MGI:3773480|PMID:18066062)

PMID:18066062 PMID:21873635

MGI:3773480, RGD:13792537

NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147

Kif3a

kinesin family member 3a

acts_upstream_of_or_within

MGI:2386464 (MGI:3773480|PMID:18066062)

PMID:18066062

MGI:3773480

NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191

Mks1

MKS transition zone complex subunit 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:4887578 (MGI:4868517|PMID:21045211)

PMID:21045211

GO_REF:0000107 MGI:4868517

NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655

myosin VIIA

acts_upstream_of_or_within

MGI:2155422 (MGI:3794916|PMID:18339676)

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

protocadherin related 15

acts_upstream_of_or_within

MGI:1856394 (MGI:3794916|PMID:18339676)

NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719

Scrib

scribble planar cell polarity protein

acts_upstream_of_or_within

MGI:5056373 (MGI:5050793|PMID:21515572)

PMID:21515572

MGI:5050793

NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331

Sdc4

syndecan 4

acts_upstream_of_or_within

MGI:2135272 (MGI:5498591|PMID:23760952)

PMID:23760952

MGI:5498591

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

Trip11

thyroid hormone receptor interactor 11

acts_upstream_of_or_within

MGI:3836913 (MGI:5615303|PMID:25605782)

NCBI chr 6:120,995,242...121,067,693
Ensembl chr 6:120,998,733...121,067,781

Tshr

thyroid stimulating hormone receptor

acts_upstream_of_or_within

(MGI:3652455|PMID:10575115)

PMID:10575115

MGI:3652455

NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538

Tsku

tsukushi, small leucine rich proteoglycan

involved_in

IEA
ISO
ISS

GO_REF:0000107
(MGI:6416702|PMID:32127020)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:32127020

GO_REF:0000024 GO_REF:0000107 MGI:6416702

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

Ttc8

tetratricopeptide repeat domain 8

acts_upstream_of_or_within

MGI:5140723 (MGI:5615303|PMID:25605782)

NCBI chr 6:118,198,186...118,252,422
Ensembl chr 6:118,198,201...118,252,418

Ush1c

USH1 protein network component harmonin

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:3757683 (MGI:3794916|PMID:18339676)

PMID:18339676 PMID:21873635

MGI:3794916, RGD:13792537

NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671

Ush1g

USH1 protein network component sans

acts_upstream_of_or_within

MGI:1856575 (MGI:3794916|PMID:18339676)

NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590

VANGL planar cell polarity protein 2

acts_upstream_of_or_within

PMID:18066062 PMID:18606138 PMID:23760952

MGI:3773480 MGI:3814781 MGI:5498591

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

Whrn

whirlin

involved_in

GO_REF:0000024
(MGI:2182951|PMID:12124769), (MGI:3714804|PMID:17326148)

PMID:12124769 PMID:17326148

GO_REF:0000024 MGI:2182951 MGI:3714804

NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223

lateral semicircular canal development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gli3

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:3709667|PMID:17395647)

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

negative regulation of inner ear auditory receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

delta like canonical Notch ligand 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1932522|MGI:3044907 (MGI:3621102|PMID:16495313)

PMID:16495313

GO_REF:0000107 MGI:3621102

NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179

fibroblast growth factor receptor 3

acts_upstream_of_or_within

MGI:1931521 (MGI:3695846|PMID:17117437)

PMID:17117437

MGI:3695846

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

hes family bHLH transcription factor 1

involved_in
acts_upstream_of_or_within

PMID:11023859 PMID:11425898 PMID:21300049

GO_REF:0000107 MGI:1889857 MGI:2136156 MGI:4949990

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

hes family bHLH transcription factor 5

acts_upstream_of_or_within

MGI:104853|MGI:1341800|MGI:2149674 (MGI:2136156|PMID:11425898), (MGI:4949990|PMID:21300049)

PMID:11425898 PMID:21300049

MGI:2136156 MGI:4949990

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

Notch1

notch receptor 1

acts_upstream_of_or_within

MGI:3044585 (MGI:5617067|PMID:25535395)

PMID:25535395

MGI:5617067

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

negative regulation of inner ear receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

hes family bHLH transcription factor 1

involved_in

(MGI:3625195|PMID:12208538)

PMID:12208538

MGI:3625195

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

hes family bHLH transcription factor 5

involved_in

(MGI:3625195|PMID:12208538)

PMID:12208538

MGI:3625195

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

otic vesicle development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ahi1

Abelson helper integration site 1

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 1:15,768,047...15,886,744
Ensembl chr 1:15,762,462...15,891,041

Col2a1

collagen type II alpha 1 chain

involved_in

(MGI:86312|PMID:9119111)

PMID:9119111

MGI:86312

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

MGI:102780 (MGI:5319720|PMID:22513373)

PMID:22513373

MGI:5319720

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

Gata3

GATA binding protein 3

acts_upstream_of_or_within

MGI:2181200 (MGI:1928163|PMID:11135239)

PMID:11135239

MGI:1928163

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

Get1

guided entry of tail-anchored proteins factor 1

acts_upstream_of_or_within

MGI:5911419|MGI:6117117 (MGI:5817553|PMID:27458190)

PMID:27458190

MGI:5817553

NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973

Pax8

paired box 8

involved_in

(PMID:15494458)

PMID:15494458

NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363

SIX homeobox 1

acts_upstream_of_or_within

MGI:109344|MGI:2655195 (MGI:3702803|PMID:16916509), (MGI:5319720|PMID:22513373)

PMID:16916509 PMID:22513373

MGI:3702803 MGI:5319720

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Sox9

SRY-box transcription factor 9

involved_in

(MGI:86312|PMID:9119111)

PMID:9119111

MGI:86312

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

otic vesicle formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fibroblast growth factor 10

acts_upstream_of_or_within

MGI:95517 (MGI:2683889|PMID:14623822)

PMID:14623822

MGI:2683889

NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866

Fgf3

fibroblast growth factor 3

acts_upstream_of_or_within

MGI:1099809|MGI:99604 (MGI:3720541|PMID:17601531)

NCBI chr 1:200,001,261...200,005,187
Ensembl chr 1:200,001,261...200,005,187

Fgf8

fibroblast growth factor 8

acts_upstream_of_or_within

MGI:95517 (MGI:3720541|PMID:17601531)

NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359

Fgfr2

fibroblast growth factor receptor 2

acts_upstream_of_or_within

MGI:2153790 (MGI:1197797|PMID:9435295)

PMID:9435295

MGI:1197797

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

Hesx1

HESX homeobox 1

acts_upstream_of_or_within

MGI:1931124 (MGI:1206234|PMID:9620767)

PMID:9620767

MGI:1206234

NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957

Sox9

SRY-box transcription factor 9

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:1932522|MGI:2385468 (MGI:3795349|PMID:18377888)

PMID:18377888

GO_REF:0000024 MGI:3795349

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

Tcap

titin-cap

involved_in

(MGI:1314551|PMID:9817758)

PMID:9817758

MGI:1314551

NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887

otic vesicle morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

MGI:2150426 (MGI:3702803|PMID:16916509)

PMID:16916509

MGI:3702803

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

T-box transcription factor 1

acts_upstream_of_or_within

MGI:3046793 (MGI:3703494|PMID:17074316)

PMID:17074316

MGI:3703494

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

otolith development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atg5

autophagy related 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3612279 (MGI:4829568|PMID:20577052)

PMID:20577052

GO_REF:0000107 MGI:4829568

NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209

Nox3

NADPH oxidase 3

acts_upstream_of_or_within

MGI:1856606 (MGI:1351720|PMID:10491954)

PMID:10491954

MGI:1351720

NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851

otolith formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc44a4

solute carrier family 44, member 4

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215

otolith mineralization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

MGI:1857876 (MGI:1275896|PMID:9668038)

PMID:9668038

MGI:1275896

NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665

Oc90

otoconin 90

involved_in

(MGI:5896790|PMID:21655225), (MGI:6189500|PMID:24748133)

PMID:21655225 PMID:24748133

MGI:5896790 MGI:6189500

NCBI chr 7:97,635,890...97,669,416
Ensembl chr 7:97,635,890...97,669,416

Otol1

otolin 1

involved_in

(MGI:5896790|PMID:21655225), (MGI:6189500|PMID:24748133), (MGI:6189669|PMID:29076638)

PMID:21655225 PMID:24748133 PMID:29076638

MGI:5896790 MGI:6189500 MGI:6189669

NCBI chr 2:154,339,612...154,349,050
Ensembl chr 2:154,339,612...154,349,023

otolith mineralization completed early in development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atg4b

autophagy related 4B, cysteine peptidase

involved_in

(MGI:4829568|PMID:20577052)

PMID:20577052

MGI:4829568

NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103

otolith morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bloc1s5

biogenesis of lysosomal organelles complex 1 subunit 5

acts_upstream_of_or_within

MGI:1856106 (MGI:53623|PMID:5367369)

PMID:5367369

MGI:53623

NCBI chr17:26,171,965...26,197,276
Ensembl chr17:26,172,018...26,197,251

Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

acts_upstream_of_or_within

MGI:2443955 (MGI:5519140|PMID:24086156)

PMID:24086156

MGI:5519140

NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513

Lrig3

leucine-rich repeats and immunoglobulin-like domains 3

acts_upstream_of_or_within

MGI:107935 (MGI:5519140|PMID:24086156)

PMID:24086156

MGI:5519140

NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481

Ttc39c

tetratricopeptide repeat domain 39C

involved_in

IBA

PMID:21873635

GO_Central

PMID:21873635

RGD:13792537

NCBI chr18:3,768,802...3,887,932
Ensembl chr18:3,805,183...3,887,930

positive regulation of inner ear auditory receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

atonal bHLH transcription factor 1

acts_upstream_of_or_within

(MGI:1889857|PMID:11023859), (MGI:3833041|PMID:19154718)

PMID:11023859 PMID:19154718

MGI:1889857 MGI:3833041

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

Fgf2

fibroblast growth factor 2

acts_upstream_of_or_within

(MGI:2429373|PMID:12417662)

PMID:12417662

MGI:2429373

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

positive regulation of inner ear receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

atonal bHLH transcription factor 1

involved_in
acts_upstream_of_or_within

(MGI:3625195|PMID:12208538)
MGI:3767172 (MGI:4939574|PMID:21146598)

PMID:12208538 PMID:21146598

MGI:3625195 MGI:4939574

NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154

positive regulation of otic vesicle morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Stox1

storkhead box 1

involved_in

(MGI:5635320|PMID:25677106)

PMID:25677106

MGI:5635320

NCBI chr20:30,598,656...30,666,371
Ensembl chr20:30,598,168...30,666,939

regulation of inner ear auditory receptor cell differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hey1

hes-related family bHLH transcription factor with YRPW motif 1

acts_upstream_of_or_within

MGI:104853|MGI:104876 (MGI:4949990|PMID:21300049)

NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312

Hey2

hes-related family bHLH transcription factor with YRPW motif 2

acts_upstream_of_or_within

MGI:104654 (MGI:3833041|PMID:19154718)

PMID:19154718

MGI:3833041

NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218

Mycl

MYCL proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

MGI:97357 (MGI:5468771|PMID:23022312)

PMID:23022312

MGI:5468771

NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582

Mycn

MYCN proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

MGI:96799 (MGI:5468771|PMID:23022312)

PMID:23022312

MGI:5468771

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

Notch1

notch receptor 1

acts_upstream_of_or_within

MGI:3044585 (MGI:5617067|PMID:25535395)

PMID:25535395

MGI:5617067

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

regulation of inner ear auditory receptor cell fate specification

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Esrp1

epithelial splicing regulatory protein 1

involved_in

GO_REF:0000024
(MGI:5915403|PMID:29107558)

PMID:29107558

GO_REF:0000024 MGI:5915403

NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062

semicircular canal development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gata2

GATA binding protein 2

acts_upstream_of_or_within

MGI:4818492 (MGI:4821520|PMID:20652952)

PMID:20652952

MGI:4821520

NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761

semicircular canal formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

homeobox A1

involved_in

(PMID:16155570)

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

semicircular canal fusion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

fibroblast growth factor 10

acts_upstream_of_or_within

MGI:1859647 (MGI:3575490|PMID:15765517)

PMID:15765517

MGI:3575490

NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866

semicircular canal morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Chd7

chromodomain helicase DNA binding protein 7

acts_upstream_of_or_within

MGI:98493 (MGI:4397600|PMID:19855134)

PMID:19855134

MGI:4397600

NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

MGI:1857803 (MGI:1335261|PMID:10072433)

PMID:10072433

MGI:1335261

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

fibroblast growth factor 10

acts_upstream_of_or_within

MGI:95517 (MGI:3720541|PMID:17601531)

NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866

Fgf3

fibroblast growth factor 3

acts_upstream_of_or_within

MGI:1099809 (MGI:3720541|PMID:17601531)

NCBI chr 1:200,001,261...200,005,187
Ensembl chr 1:200,001,261...200,005,187

Nr4a3

nuclear receptor subfamily 4, group A, member 3

acts_upstream_of_or_within

MGI:3037444 (MGI:2157256|PMID:11784868)

PMID:11784868

MGI:2157256

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

T-box transcription factor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2444748 (MGI:4397600|PMID:19855134)

PMID:19855134

GO_REF:0000024 MGI:4397600

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

Tbx3

T-box transcription factor 3

involved_in

(MGI:6710296|PMID:33795231)

PMID:33795231

MGI:6710296

NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708

Zeb1

zinc finger E-box binding homeobox 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1861230 (MGI:5294688|PMID:21980308)

PMID:21980308

GO_REF:0000107 MGI:5294688

NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214

stereocilium maintenance

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Clrn2

clarin 2

acts_upstream_of_or_within
involved_in

MGI:5792002|MGI:6458758 (MGI:6376373|PMID:31448880)
(MGI:6810803|PMID:33496845)

PMID:31448880 PMID:33496845

MGI:6376373 MGI:6810803

NCBI chr14:65,656,550...65,666,193
Ensembl chr14:65,656,550...65,666,193

Pjvk

pejvakin

acts_upstream_of_or_within

MGI:5014098|MGI:5925280 (MGI:5887150|PMID:28209736)

PMID:28209736

MGI:5887150

NCBI chr 3:61,594,644...61,605,051
Ensembl chr 3:61,596,641...61,605,045

Tprn

taperin

involved_in

MGI:5897817 (MGI:5887167|PMID:27693694)
PMID:21873635

PMID:27693694 PMID:21873635

MGI:5887167, RGD:13792537

NCBI chr 3:8,076,164...8,083,642
Ensembl chr 3:8,075,137...8,083,642

vestibular receptor cell development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

glutaredoxin and cysteine rich domain containing 1

involved_in

(MGI:3512691|PMID:11276175)

PMID:11276175

MGI:3512691

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

vestibular receptor cell morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptprq

protein tyrosine phosphatase, receptor type, Q

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2679316 (MGI:5315778|PMID:22357859)

PMID:22357859

GO_REF:0000107 MGI:5315778

NCBI chr 7:42,837,109...43,016,917
Ensembl chr 7:42,837,109...43,016,917

vestibular receptor cell stereocilium organization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pls1

plastin 1

involved_in

(MGI:5608770|PMID:25124451)