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ONTOLOGY REPORT - ANNOTATIONS

Term:cytoskeleton of presynaptic active zone
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Accession:GO:0048788 term browser browse the term
Definition:The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.
Synonyms:exact_synonym: active zone cytomatrix;   presynaptic cytomatrix assembled at active zones;   presynaptic cytoskeletal matrix;   presynaptic cytoskeletal matrix assembled at active zones
 narrow_synonym: CAZ;   T-bar;   T-bar ribbon;   pre-synaptic dense body;   presynaptic dense body;   synaptic ribbon
 related_synonym: pre-synaptic cytoskeletal matrix assembled at active zones;   pre-synaptic ribbon;   presynaptic ribbon;   ribbon
 xref: NIF_Subcellular:sao1470121605


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cytoskeleton of presynaptic active zone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon (presynaptic cytomatrix protein) located_in
is_active_in		 IDA
IBA		 PMID:9679147
GO_REF:0000033		 GO_Central
RGD		 PMID:11596050 PMID:9679147 GO_REF:0000033, RGD:9850129, RGD:69780 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639 		JBrowse link
G Erc2 ELKS/RAB6-interacting/CAST family member 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:2,812,712...3,673,624
Ensembl chr16:2,848,620...3,670,776 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) is_active_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11596050 GO_REF:0000033, RGD:9850129 NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489 		JBrowse link
G Rims4 regulating synaptic membrane exocytosis 4 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:152,520,982...152,585,070
Ensembl chr 3:152,524,095...152,584,780 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      presynaptic active zone 144
        presynaptic active zone cytoplasmic component 23
          cytoskeleton of presynaptic active zone 8
            presynaptic density + 0
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      organelle 14001
        non-membrane-bounded organelle 5255
          intracellular non-membrane-bounded organelle 5255
            cytoskeleton 2367
              cortical cytoskeleton 129
                cytoskeleton of presynaptic active zone 8
                  presynaptic density + 0
paths to the root