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ONTOLOGY REPORT - ANNOTATIONS

Term:astrocyte differentiation
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Accession:GO:0048708 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.


show annotations for term's descendants           Sort by:
astrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 IMP RGD PMID:17141959 RGD:2303044 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Actr3 actin related protein 3 IMP RGD PMID:23843614 RGD:8553949 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of
involved_in		 ISO
IEA		 MGI:99414 (MGI:3577784|PMID:15882580)
GO_REF:0000107		 RGD
Ensembl		 PMID:15882580 GO_REF:0000107 MGI:3577784 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Cul4b cullin 4B involved_in ISO MGI:5500946 (MGI:5660665|PMID:26025376) RGD PMID:26025376 MGI:5660665 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Dab1 DAB adaptor protein 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:1857750 (MGI:3839063|PMID:18848628)
GO_REF:0000107		 RGD
Ensembl		 PMID:18848628 GO_REF:0000107 MGI:3839063 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO
ISS		 (PMID:15723074)
GO_REF:0000024		 RGD
UniProt		 PMID:15723074 GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Eomes eomesodermin involved_in ISO (MGI:6220563|PMID:30186101) RGD PMID:30186101 MGI:6220563 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of ISO MGI:1931521 (MGI:2450226|PMID:12574417) RGD PMID:12574417 MGI:2450226 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Gap43 growth associated protein 43 acts_upstream_of_or_within ISO MGI:2180341 (MGI:3531391|PMID:15234344) RGD PMID:15234344 MGI:3531391 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284803|PMID:15156153)		 UniProt
RGD		 PMID:15156153 GO_REF:0000024 MGI:5284803 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hmbs hydroxymethylbilane synthase IEP RGD PMID:12917623 RGD:2301689 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmga2 high mobility group AT-hook 2 acts_upstream_of ISO (MGI:3814762|PMID:18640244) RGD PMID:18640244 MGI:3814762 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of ISO MGI:3830733 (MGI:3829299|PMID:19109490) RGD PMID:19109490 MGI:3829299 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id4 inhibitor of DNA binding 4 acts_upstream_of ISO MGI:88177 (MGI:3577784|PMID:15882580) RGD PMID:15882580 MGI:3577784 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 acts_upstream_of_or_within ISO MGI:1856965|MGI:3510641 (MGI:3588182|PMID:16111892) RGD PMID:16111892 MGI:3588182 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Lif LIF, interleukin 6 family cytokine IMP RGD PMID:17328769 RGD:2326156 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3814762|PMID:18640244)
GO_REF:0000107		 RGD
Ensembl		 PMID:18640244 GO_REF:0000107 MGI:3814762 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:3664706|PMID:12111813) RGD PMID:12111813 MGI:3664706 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of ISO MGI:1857444|MGI:2176055|MGI:2176057 (MGI:1327500|PMID:9878702), (MGI:1342880|PMID:10442636), (MGI:1932841|PMID:11297510) RGD PMID:9878702 PMID:10442636 PMID:11297510 MGI:1327500 MGI:1342880 MGI:1932841 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within
involved_in		 ISO MGI:3802571 (MGI:5436217|PMID:21800304)
MGI:3802571 (MGI:6104294|PMID:29106906)		 RGD PMID:21800304 PMID:29106906 MGI:5436217 MGI:6104294 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (MGI:3840409|PMID:19258013) RGD PMID:19258013 MGI:3840409 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Notch1 notch receptor 1 IDA RGD PMID:19378247 RGD:2325301 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 acts_upstream_of ISO MGI:2176560 (MGI:2686847|PMID:14702088) RGD PMID:14702088 MGI:2686847 NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in ISO
IEA		 (MGI:6196751|PMID:29890290)
GO_REF:0000107		 RGD
Ensembl		 PMID:29890290 GO_REF:0000107 MGI:6196751 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA		 (MGI:6220563|PMID:30186101)
MGI:1856155 (MGI:3840409|PMID:19258013)
GO_REF:0000107		 RGD
Ensembl		 PMID:19258013 PMID:30186101 PMID:22944581 GO_REF:0000107 MGI:3840409 MGI:6220563, RGD:8552357 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G S100b S100 calcium binding protein B IEP RGD PMID:19147496 RGD:5508832 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of ISO (MGI:1337447|PMID:10357934) RGD PMID:10357934 MGI:1337447 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sox6 SRY-box transcription factor 6 IMP RGD PMID:15846364 RGD:1581115 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5284803|PMID:15156153)		 UniProt
Ensembl
RGD		 PMID:15156153 GO_REF:0000024 GO_REF:0000107 MGI:5284803 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Vax1 ventral anterior homeobox 1 acts_upstream_of_or_within ISO MGI:1859863 (MGI:3531600|PMID:15590934) RGD PMID:15590934 MGI:3531600 NCBI chr 1:258,324,571...258,342,396
Ensembl chr 1:258,326,276...258,330,192 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO
IEA		 MGI:1857091 (MGI:6196751|PMID:29890290)
GO_REF:0000107		 RGD
Ensembl		 PMID:29890290 GO_REF:0000107 MGI:6196751 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP RGD PMID:12838511 RGD:1625689 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 UniProtKB:P05067 (PMID:15457210)
GO_REF:0000107		 RGD
Ensembl		 PMID:15457210 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2136636 (MGI:2385816|PMID:9734405) RGD PMID:9734405 MGI:2385816 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:P49768|UniProtKB:Q15109 (PMID:15457210), (PMID:20445063) RGD PMID:15457210 PMID:20445063 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bace2 beta-secretase 2 IEP RGD PMID:21073551 RGD:13782176 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G C1qa complement C1q A chain involved_in ISO
IEA		 UniProtKB:P05067 (MGI:3607035|PMID:15269255)
GO_REF:0000107		 RGD
Ensembl		 PMID:15269255 GO_REF:0000107 MGI:3607035 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO UniProtKB:P05067 (MGI:4354701|PMID:19561098) RGD PMID:19561098 MGI:4354701 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Cntf ciliary neurotrophic factor involved_in IDA
IBA		 spinal cord astrocytes
PMID:21873635		 RGD
GO_Central		 PMID:11771938 PMID:21873635 RGD:1626172, RGD:13792537 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:16837601 RGD:1581900 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:18375019)
UniProtKB:P05067 (MGI:4454469|PMID:20368278)		 RGD PMID:18375019 PMID:20368278 MGI:4454469 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P05067 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6141363|PMID:28377412)
GO_REF:0000107		 RGD
Ensembl		 PMID:28377412 GO_REF:0000107 MGI:6141363 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mt2A metallothionein 2A IEP RGD PMID:19837066 RGD:6483825 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:6219748|PMID:26607664) RGD PMID:26607664 MGI:6219748 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:P05067 (PMID:20445063) RGD PMID:20445063 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176256 (MGI:5510940|PMID:23680462)		 Ensembl
RGD		 PMID:23680462 GO_REF:0000107 MGI:5510940 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO UniProtKB:P10636 (MGI:6095556|PMID:29073081) RGD PMID:29073081 MGI:6095556 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IDA RGD PMID:34852714 RGD:155882542 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
astrocyte activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:A0A0R4J0I9|UniProtKB:P49768 (PMID:23152628)
GO_REF:0000107		 RGD
Ensembl		 PMID:23152628 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(MGI:4421471|PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 MGI:4421471 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5465209|PMID:23152628) RGD PMID:23152628 MGI:5465209 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Psen1 presenilin 1 involved_in ISO UniProtKB:A0A0R4J0I9|UniProtKB:P05067 (PMID:23152628) RGD PMID:23152628 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
astrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor acts_upstream_of_or_within ISO (MGI:5440388|PMID:22577135) RGD PMID:22577135 MGI:5440388 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5504540|PMID:23688253)		 Ensembl
UniProt
RGD		 PMID:23688253 GO_REF:0000024 GO_REF:0000107 MGI:5504540 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181426|MGI:3707260 (MGI:3703826|PMID:17360497)		 Ensembl
RGD		 PMID:17360497 GO_REF:0000107 MGI:3703826 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO
ISS		 (PMID:15723074)
GO_REF:0000024		 RGD
UniProt		 PMID:15723074 GO_REF:0000024 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Gfap glial fibrillary acidic protein acts_upstream_of_or_within ISO MGI:98932 (MGI:3719550|PMID:11487638) RGD PMID:11487638 MGI:3719550 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Lamb2 laminin subunit beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1344394 (MGI:4454394|PMID:19907020)		 Ensembl
RGD		 PMID:19907020 GO_REF:0000107 MGI:4454394 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549 		JBrowse link
G Lamc3 laminin subunit gamma 3 acts_upstream_of_or_within ISO MGI:99916 (MGI:4454394|PMID:19907020) RGD PMID:19907020 MGI:4454394 NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697 		JBrowse link
G Plp1 proteolipid protein 1 acts_upstream_of_or_within ISO MGI:1917997 (MGI:5511081|PMID:24038504) RGD PMID:24038504 MGI:5511081 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 IDA RGD PMID:15095375 RGD:11537371 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IDA RGD PMID:15095375 RGD:11537371 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G S100a8 S100 calcium binding protein A8 acts_upstream_of_or_within ISO MGI:1338947 (MGI:5440388|PMID:22577135) RGD PMID:22577135 MGI:5440388 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:88244 (MGI:5440388|PMID:22577135)		 RGD PMID:22577135 PMID:21873635 MGI:5440388, RGD:13792537 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5440388|PMID:22577135)
GO_REF:0000107		 RGD
Ensembl		 PMID:22577135 GO_REF:0000107 MGI:5440388 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tspan2 tetraspanin 2 acts_upstream_of_or_within ISO MGI:5556057|MGI:97623 (MGI:5511081|PMID:24038504) RGD PMID:24038504 MGI:5511081 NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660 		JBrowse link
G Vim vimentin acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:95697 (MGI:3719550|PMID:11487638)
GO_REF:0000107		 RGD
Ensembl		 PMID:11487638 GO_REF:0000107 MGI:3719550 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
astrocyte fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcm1 glial cells missing transcription factor 1 acts_upstream_of_or_within ISO (MGI:3630207|PMID:14573516) RGD PMID:14573516 MGI:3630207 NCBI chr 8:78,925,687...78,938,924
Ensembl chr 8:78,925,687...78,938,924 		JBrowse link
G Sox8 SRY-box transcription factor 8 acts_upstream_of_or_within ISO MGI:98371 (MGI:4368088|PMID:19490914) RGD PMID:19490914 MGI:4368088 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:98370 (MGI:4368088|PMID:19490914) RGD PMID:19490914 MGI:4368088 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:2176173|MGI:2661471 (MGI:3768218|PMID:16292311) RGD PMID:16292311 MGI:3768218 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976 		JBrowse link
Bergmann glial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87860 (MGI:4840122|PMID:20980600) RGD PMID:20980600 MGI:4840122 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:87859 (MGI:4840122|PMID:20980600) RGD PMID:20980600 MGI:4840122 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Gfap glial fibrillary acidic protein acts_upstream_of_or_within ISO MGI:2183221 (MGI:1858866|PMID:10816608) RGD PMID:10816608 MGI:1858866 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of ISO MGI:5439169 (MGI:5512663|PMID:24062445) RGD PMID:24062445 MGI:5512663 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99511 (MGI:5545830|PMID:24431450)		 Ensembl
RGD		 PMID:24431450 GO_REF:0000107 MGI:5545830 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1346859 (MGI:5545830|PMID:24431450)
GO_REF:0000107		 RGD
Ensembl		 PMID:24431450 GO_REF:0000107 MGI:5545830 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO MGI:1346858 (MGI:5545830|PMID:24431450) RGD PMID:24431450 MGI:5545830 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Plpp3 phospholipid phosphatase 3 acts_upstream_of_or_within ISO MGI:2176173|MGI:3723633 (MGI:4939815|PMID:21319224) RGD PMID:21319224 MGI:4939815 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1346866|MGI:4868451 (MGI:5545830|PMID:24431450)
GO_REF:0000107		 RGD
Ensembl		 PMID:24431450 GO_REF:0000107 MGI:5545830 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:1338342|PMID:10375501)		 Ensembl
RGD		 PMID:10375501 GO_REF:0000107 MGI:1338342 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544|MGI:2179048|MGI:5587034 (MGI:6152587|PMID:29615573) RGD PMID:29615573 MGI:6152587 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Vim vimentin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1931877 (MGI:1858866|PMID:10816608)		 Ensembl
RGD		 PMID:10816608 GO_REF:0000107 MGI:1858866 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
forebrain astrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras KRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:2429948 (MGI:5440388|PMID:22577135) RGD PMID:22577135 MGI:5440388 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
MGI:1857444 (MGI:3579920|PMID:15944386)
GO_REF:0000024		 Ensembl
RGD
HGNC-UCL		 PMID:15944386 GO_REF:0000024 GO_REF:0000107 MGI:3579920 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857996 (MGI:77941|PMID:8543156)
GO_REF:0000107		 RGD
Ensembl		 PMID:8543156 GO_REF:0000107 MGI:77941 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
negative regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IEA		 UniProtKB:P05067|UniProtKB:P49768 (MGI:4415751|PMID:20005821)
GO_REF:0000107		 RGD
Ensembl		 PMID:20005821 GO_REF:0000107 MGI:4415751 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6283959|PMID:30792350)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:30792350 GO_REF:0000024 GO_REF:0000107 MGI:6283959 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6152919|PMID:29407460) RGD PMID:29407460 MGI:6152919 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of astrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf5 activating transcription factor 5 IMP RGD PMID:15829641 RGD:2302988 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Dab1 DAB adaptor protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857750 (MGI:3839063|PMID:18848628)
GO_REF:0000107		 RGD
Ensembl		 PMID:18848628 GO_REF:0000107 MGI:3839063 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Dll3 delta like canonical Notch ligand 3 IDA RGD PMID:16144902 RGD:1599776 NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750 		JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA		 (PMID:1691280)
GO_REF:0000107		 RGD
Ensembl		 PMID:1691280 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:2450226|PMID:12574417) RGD PMID:12574417 MGI:2450226 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of_or_within ISO MGI:5439169 (MGI:5512663|PMID:24062445) RGD PMID:24062445 MGI:5512663 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2655020|PMID:12666205)		 UniProt
RGD		 PMID:12666205 GO_REF:0000024 MGI:2655020 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hmga2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:3814762|PMID:18640244) RGD PMID:18640244 MGI:3814762 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Id4 inhibitor of DNA binding 4 acts_upstream_of_or_within ISO MGI:88177 (MGI:3577784|PMID:15882580) RGD PMID:15882580 MGI:3577784 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470 		JBrowse link
G Kdm4a lysine demethylase 4A IMP RGD PMID:24747049 RGD:9587433 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 IDA RGD PMID:16881068 RGD:9588644 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IDA RGD PMID:16881068 RGD:9588644 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3814762|PMID:18640244)
GO_REF:0000107		 RGD
Ensembl		 PMID:18640244 GO_REF:0000107 MGI:3814762 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857444|MGI:2176055|MGI:2176057 (MGI:1327500|PMID:9878702), (MGI:1342880|PMID:10442636), (MGI:1932841|PMID:11297510)		 Ensembl
RGD		 PMID:9878702 PMID:10442636 PMID:11297510 GO_REF:0000107 MGI:1327500 MGI:1342880 MGI:1932841 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nog noggin involved_in IMP
ISO
IEA
ISS		 (MGI:3808973|PMID:18028109)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18028109 PMID:14975730 GO_REF:0000024 GO_REF:0000107 MGI:3808973, RGD:1358325 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 acts_upstream_of_or_within ISO MGI:2176560 (MGI:2686847|PMID:14702088) RGD PMID:14702088 MGI:2686847 NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IMP RGD PMID:12075995 RGD:2325633 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
positive regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33841088 RGD:151665762 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
positive regulation of astrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP RGD PMID:23843614 RGD:8553949 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Bin1 bridging integrator 1 involved_in ISO
ISS
IEA		 (PMID:10412034)
GO_REF:0000024
GO_REF:0000107		 RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:10412034 GO_REF:0000024 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99414 (MGI:1343608|PMID:10486560), (MGI:3577784|PMID:15882580)		 Ensembl
RGD		 PMID:10486560 PMID:15882580 GO_REF:0000107 MGI:1343608 MGI:3577784 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:5009184|PMID:12090754) RGD PMID:12090754 MGI:5009184 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2655020|PMID:12666205)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12666205 GO_REF:0000024 GO_REF:0000107 MGI:2655020 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:3830733 (MGI:3829299|PMID:19109490) RGD PMID:19109490 MGI:3829299 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:22270046 RGD:6482669 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer acts_upstream_of_or_within ISO (MGI:1343608|PMID:10486560) RGD PMID:10486560 MGI:1343608 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Lif LIF, interleukin 6 family cytokine acts_upstream_of_or_within ISO (MGI:1343608|PMID:10486560) RGD PMID:10486560 MGI:1343608 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mag myelin-associated glycoprotein IDA RGD PMID:19349915 RGD:9685287 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2655020|PMID:12666205)		 UniProt
RGD		 PMID:12666205 GO_REF:0000024 MGI:2655020 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 acts_upstream_of_or_within IMP
ISO		 (MGI:3640624|PMID:16352598) RGD PMID:16352598 PMID:23769735 MGI:3640624, RGD:10045891 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IEA		 (PMID:1691280)
GO_REF:0000107		 RGD
Ensembl		 PMID:1691280 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1337447|PMID:10357934)
GO_REF:0000107		 RGD
Ensembl		 PMID:10357934 GO_REF:0000107 MGI:1337447 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
regulation of astrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntn2 contactin 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3530975|PMID:15537875)		 UniProt
RGD		 PMID:15537875 GO_REF:0000024 MGI:3530975 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19527
    cellular process 18201
      cellular developmental process 4626
        cell differentiation 4625
          glial cell differentiation 320
            astrocyte differentiation 98
              Bergmann glial cell differentiation 12
              astrocyte development + 40
              astrocyte fate commitment + 4
              forebrain astrocyte differentiation + 3
              negative regulation of astrocyte differentiation + 20
              positive regulation of astrocyte differentiation + 15
              regulation of astrocyte differentiation + 37
Path 2
Term Annotations click to browse term
  biological_process 19527
    developmental process 6898
      anatomical structure development 6425
        multicellular organism development 5175
          system development 4453
            nervous system development 2730
              neurogenesis 2039
                gliogenesis 435
                  glial cell differentiation 320
                    astrocyte differentiation 98
                      Bergmann glial cell differentiation 12
                      astrocyte development + 40
                      astrocyte fate commitment + 4
                      forebrain astrocyte differentiation + 3
                      negative regulation of astrocyte differentiation + 20
                      positive regulation of astrocyte differentiation + 15
                      regulation of astrocyte differentiation + 37
paths to the root