skeletal system morphogenesis - Ontology Report

MGI:1857709|MGI:98728 (MGI:3689276|PMID:16991118), (MGI:3695190|PMID:16845371)

PMID:16845371 PMID:16991118

MGI:3689276 MGI:3695190

NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458

Alx4

ALX homeobox 4

acts_upstream_of_or_within

MGI:1857484 (MGI:1098911|PMID:9374397)

PMID:9374397

MGI:1098911

NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260

Ankrd11

ankyrin repeat domain containing 11

acts_upstream_of_or_within

(PMID:21782149)
MGI:3797584 (MGI:3796348|PMID:17986521)

PMID:17986521 PMID:21782149

MGI:3796348

NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962

Arid5b

AT-rich interaction domain 5B

acts_upstream_of_or_within

MGI:3526852 (MGI:3696608|PMID:17143286)

NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433

Col11a1

collagen type XI alpha 1 chain

acts_upstream_of_or_within

MGI:1856399 (MGI:70833|PMID:7859283)

PMID:7859283

MGI:70833

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

Col11a2

collagen type XI alpha 2 chain

acts_upstream_of_or_within

MGI:2154689 (MGI:2151300|PMID:11668593)

PMID:11668593

MGI:2151300

NCBI chr20:4,786,929...4,816,598
Ensembl chr20:4,786,929...4,815,985

collagen type I alpha 1 chain

acts_upstream_of_or_within

MGI:97009 (MGI:3710444|PMID:17440987)

MGI:3710444

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

collagen type II alpha 1 chain

acts_upstream_of_or_within

PMID:7276808 PMID:7590256 PMID:8192242 PMID:9915573

MGI:1327515 MGI:55057 MGI:65233 MGI:77563

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Csrnp1

cysteine and serine rich nuclear protein 1

acts_upstream_of_or_within

MGI:3526868 (MGI:3696608|PMID:17143286)

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

Fgr

FGR proto-oncogene, Src family tyrosine kinase

acts_upstream_of_or_within

MGI:3665439 (MGI:3663851|PMID:16964445)

PMID:16964445

MGI:3663851

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

Fmn1

formin 1

acts_upstream_of_or_within

MGI:3718051 (MGI:3717025|PMID:17554679)

PMID:17554679

MGI:3717025

NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220

Hhip

Hedgehog-interacting protein

involved_in

(MGI:1333378|PMID:10050855)

PMID:10050855

MGI:1333378

NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528

Hoxb2

homeobox B2

acts_upstream_of_or_within

MGI:2151772|MGI:96185 (MGI:85074|PMID:9012503)

PMID:9012503

MGI:85074

NCBI chr10:81,317,927...81,320,223
Ensembl chr10:81,318,026...81,320,192

Hoxb4

homeo box B4

acts_upstream_of_or_within

MGI:2388364|MGI:96183 (MGI:85074|PMID:9012503)

PMID:9012503

MGI:85074

NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128

Hoxb8

homeo box B8

acts_upstream_of_or_within

MGI:1934178|MGI:96198|MGI:96209 (MGI:1933164|PMID:11311170)

PMID:11311170

MGI:1933164

NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638

Hoxc8

homeobox C8

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2149030|MGI:96189|MGI:96209 (MGI:1933164|PMID:11311170)

PMID:11311170

GO_REF:0000107 MGI:1933164

NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:134,127,913...134,130,503

Hoxd8

homeobox D8

acts_upstream_of_or_within

MGI:2151815|MGI:96189|MGI:96198 (MGI:1933164|PMID:11311170)

PMID:11311170

MGI:1933164

NCBI chr 3:59,607,864...59,610,358
Ensembl chr 3:59,607,996...59,610,361

Hyal2

hyaluronidase 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3836764 (MGI:3836537|PMID:18772348)

PMID:18772348

GO_REF:0000107 MGI:3836537

NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850

Idua

alpha-L-iduronidase

acts_upstream_of_or_within

MGI:2176236 (MGI:86916|PMID:9097952)

PMID:9097952

MGI:86916

NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522

Lama5

laminin subunit alpha 5

involved_in

(PMID:33242826)

PMID:33242826

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

Lrp6

LDL receptor related protein 6

acts_upstream_of_or_within

MGI:2673982 (MGI:3055483|PMID:15469977)

PMID:15469977

MGI:3055483

NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497

Mmp2

matrix metallopeptidase 2

acts_upstream_of_or_within

MGI:88467 (MGI:3710444|PMID:17440987)

MGI:3710444

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

Myc

MYC proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

MGI:2178233|MGI:2386570 (MGI:3712581|PMID:17523175)

PMID:17523175

MGI:3712581

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

Nkx3-2

NK3 homeobox 2

acts_upstream_of_or_within

MGI:1857926 (MGI:1347483|PMID:10572046)

PMID:10572046

MGI:1347483

NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061

Nle1

notchless homolog 1

acts_upstream_of_or_within

MGI:2176174|MGI:5553357 (MGI:5608557|PMID:24824078)

PMID:24824078

MGI:5608557

NCBI chr10:67,834,059...67,844,771
Ensembl chr10:67,834,062...67,842,658

P2rx7

purinergic receptor P2X 7

acts_upstream_of_or_within

MGI:2386080 (MGI:3797675|PMID:18519738)

PMID:18519738

MGI:3797675

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

Pdgfra

platelet derived growth factor receptor alpha

acts_upstream_of_or_within

MGI:1926728 (MGI:3696608|PMID:17143286)

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Pdgfrb

platelet derived growth factor receptor beta

acts_upstream_of_or_within

MGI:2135508 (MGI:3696608|PMID:17143286)

NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843

Plekha1

pleckstrin homology domain containing A1

acts_upstream_of_or_within

MGI:3526857 (MGI:3696608|PMID:17143286)

NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156

Prkra

protein activator of interferon induced protein kinase EIF2AK2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3626341 (MGI:3623660|PMID:16571658)

PMID:16571658

GO_REF:0000107 MGI:3623660

NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347

Psen1

presenilin 1

acts_upstream_of_or_within

MGI:1857974 (MGI:87705|PMID:9160754)

PMID:9160754

MGI:87705

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Rab33b

RAB33B, member RAS oncogene family

involved_in

(PMID:23042644)

PMID:23042644

NCBI chr 2:135,528,116...135,538,719
Ensembl chr 2:135,528,116...135,538,719

Recql4

RecQ like helicase 4

acts_upstream_of_or_within

MGI:3045113 (MGI:3574257|PMID:15703196)

PMID:15703196

MGI:3574257

NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619

Rflna

refilin A

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1923816 (MGI:5570967|PMID:24436304)

PMID:24436304 PMID:21873635

MGI:5570967, RGD:13792537

NCBI chr12:31,633,361...31,642,317
Ensembl chr12:31,633,361...31,642,317

Rflnb

refilin B

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:1920371 (MGI:5570967|PMID:24436304)

PMID:24436304 PMID:21873635

MGI:5570967, RGD:13792537

NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976

Runx2

RUNX family transcription factor 2

acts_upstream_of_or_within

MGI:2176465 (MGI:3042355|PMID:15030764)

MGI:3042355

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

Ryk

receptor-like tyrosine kinase

acts_upstream_of_or_within

MGI:2667542 (MGI:2667521|PMID:10932185)

PMID:10932185

MGI:2667521

NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698

Schip1

schwannomin interacting protein 1

acts_upstream_of_or_within

MGI:3526869 (MGI:3696608|PMID:17143286)

NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585

Sgpl1

sphingosine-1-phosphate lyase 1

acts_upstream_of_or_within

MGI:3526851 (MGI:3696608|PMID:17143286)

NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084

Sh3pxd2b

SH3 and PX domains 2B

involved_in

(MGI:5800302|PMID:27711054)

PMID:27711054

MGI:5800302

NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170

Sik3

SIK family kinase 3

acts_upstream_of_or_within

MGI:5317918 (MGI:5316542|PMID:22318228)

PMID:22318228

MGI:5316542

NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444

Six1

SIX homeobox 1

acts_upstream_of_or_within

MGI:2655195 (MGI:2671031|PMID:12874121)

PMID:12874121

MGI:2671031

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Spef2

sperm flagellar 2

acts_upstream_of_or_within

MGI:5295267 (MGI:5292446|PMID:21715716)

PMID:21715716

MGI:5292446

NCBI chr 2:58,512,489...58,694,718
Ensembl chr 2:58,512,489...58,694,664

Tbx4

T-box transcription factor 4

involved_in

(PMID:15106123)

PMID:15106123

NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825

Tcf15

transcription factor 15

acts_upstream_of_or_within

MGI:1929775 (MGI:84545|PMID:8955271)

PMID:8955271

MGI:84545

NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766

Tfap2a

transcription factor AP-2 alpha

acts_upstream_of_or_within

MGI:1888387 (MGI:80520|PMID:8622765)

PMID:8622765

MGI:80520

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

Tgfbr1

transforming growth factor, beta receptor 1

acts_upstream_of_or_within

MGI:87912 (MGI:3695190|PMID:16845371)

PMID:16845371

MGI:3695190

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

Tiparp

TCDD-inducible poly(ADP-ribose) polymerase

acts_upstream_of_or_within

MGI:3526866 (MGI:3696608|PMID:17143286)

NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327

Wdr48

WD repeat domain 48

acts_upstream_of_or_within

MGI:3877670 (MGI:5547894|PMID:24001775)

PMID:24001775

MGI:5547894

NCBI chr 8:119,622,053...119,655,264
Ensembl chr 8:119,622,048...119,655,264

Wnt7a

Wnt family member 7A

acts_upstream_of_or_within

MGI:1857009

MGI:48652

NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981

Wwox

WW domain-containing oxidoreductase

acts_upstream_of_or_within

MGI:3704944 (MGI:3804353|PMID:18487609)

PMID:18487609

MGI:3804353

NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391

Zfand5

zinc finger AN1-type containing 5

acts_upstream_of_or_within

MGI:3526860 (MGI:3696608|PMID:17143286)

NCBI chr 1:218,765,735...218,776,118
Ensembl chr 1:218,766,614...218,775,843

Zfp80

zinc finger protein 80

involved_in

IEA

GO_REF:0000107

Ensembl

GO_REF:0000107

NCBI chr 1:260,248,231...260,265,211
Ensembl chr 1:260,236,599...260,265,254

bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acp5

acid phosphatase 5, tartrate resistant

acts_upstream_of_or_within

MGI:2180086 (MGI:83673|PMID:8898228)

PMID:8898228

MGI:83673

NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929

Actn3

actinin alpha 3

involved_in

(MGI:5291888|PMID:21784188)

PMID:21784188

MGI:5291888

NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012

Atg9a

autophagy related 9A

involved_in

GO_REF:0000024
(MGI:5906103|PMID:27811852)

PMID:27811852

GO_REF:0000024 MGI:5906103

NCBI chr 9:76,677,403...76,688,035
Ensembl chr 9:76,677,404...76,687,986

Cdx1

caudal type homeo box 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2154514|MGI:97858 (MGI:2154839|PMID:11784046)

PMID:11784046

GO_REF:0000107 MGI:2154839

NCBI chr18:54,472,448...54,499,799
Ensembl chr18:54,473,444...54,490,814

Chsy1

chondroitin sulfate synthase 1

acts_upstream_of_or_within

MGI:5007063 (MGI:5316547|PMID:22280990)

PMID:22280990

MGI:5316547

NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601

Cited2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

acts_upstream_of_or_within

MGI:2179740 (MGI:4457799|PMID:20549734)

PMID:20549734

MGI:4457799

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

Col9a1

collagen type IX alpha 1 chain

acts_upstream_of_or_within

MGI:88469 (MGI:3807836|PMID:18191556)

PMID:18191556

MGI:3807836

NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213

Comp

cartilage oligomeric matrix protein

acts_upstream_of_or_within

MGI:88465 (MGI:3807836|PMID:18191556)

PMID:18191556

MGI:3807836

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

Cst5

cystatin D

involved_in

MGI:3629665 (MGI:3629269|PMID:16680148)

PMID:16680148

MGI:3629269

NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754

Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

involved_in

(PMID:22019272)

PMID:22019272

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

Dhrs3

dehydrogenase/reductase 3

acts_upstream_of_or_within

MGI:5007106 (MGI:5528782|PMID:24005908)

PMID:24005908

MGI:5528782

NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417

Dlx5

distal-less homeobox 5

acts_upstream_of_or_within

MGI:2180474 (MGI:3611627|PMID:16330189)

PMID:16330189

MGI:3611627

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

exostosin glycosyltransferase 1

acts_upstream_of_or_within

(MGI:4431165|PMID:20080592), (MGI:4834113|PMID:20404326)

PMID:20080592 PMID:20404326

MGI:4431165 MGI:4834113

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

Fgfr2

fibroblast growth factor receptor 2

acts_upstream_of_or_within

MGI:2153799 (MGI:1346744|PMID:10518547)

PMID:10518547

MGI:1346744

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

Fgfr3

fibroblast growth factor receptor 3

acts_upstream_of_or_within
involved_in

MGI:1931521 (MGI:4352984|PMID:19407216)
(MGI:4457789|PMID:20582225)

PMID:19407216 PMID:20582225

MGI:4352984 MGI:4457789

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

Glg1

golgi glycoprotein 1

acts_upstream_of_or_within
involved_in

MGI:4829764 (MGI:4829577|PMID:20530870)
GO_REF:0000107

PMID:20530870

GO_REF:0000107 MGI:4829577

NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178

Has2

hyaluronan synthase 2

acts_upstream_of_or_within

MGI:2176070|MGI:4360705 (MGI:4880794|PMID:21246657)

PMID:21246657

MGI:4880794

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

Ifitm5

interferon induced transmembrane protein 5

involved_in

(MGI:5607401|PMID:20838829)
(PMID:24519609)
PMID:21873635

PMID:20838829 PMID:24519609 PMID:21873635

MGI:5607401, RGD:13792537

NCBI chr 1:196,045,836...196,052,554
Ensembl chr 1:196,045,666...196,047,232

intraflagellar transport 80

acts_upstream_of_or_within

MGI:3856827 (MGI:4940140|PMID:21227999)

PMID:21227999

MGI:4940140

NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024

Lrp5

LDL receptor related protein 5

involved_in

(PMID:19673927), (PMID:20146170), (PMID:20630166)
PMID:21873635

PMID:19673927 PMID:20146170 PMID:20630166 PMID:21873635

NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581

Lrp6

LDL receptor related protein 6

acts_upstream_of_or_within

MGI:1861309

MGI:61254

NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497

Ltbp3

latent transforming growth factor beta binding protein 3

acts_upstream_of_or_within

MGI:2180017 (MGI:2178869|PMID:11790802), (MGI:4829577|PMID:20530870)

PMID:11790802 PMID:20530870

MGI:2178869 MGI:4829577

NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975

Ltf

lactotransferrin

involved_in

(PMID:15166119)

PMID:15166119

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

Mmp13

matrix metallopeptidase 13

involved_in

GO_REF:0000024
(PMID:16167086)

PMID:16167086

GO_REF:0000024

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

Msx1

msh homeobox 1

acts_upstream_of_or_within

MGI:1933766|MGI:97169 (MGI:3608570|PMID:12489152), (MGI:3611627|PMID:16330189), (MGI:3723565|PMID:17693062)

PMID:12489152 PMID:16330189 PMID:17693062

MGI:3608570 MGI:3611627 MGI:3723565

NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966

Msx2

msh homeobox 2

acts_upstream_of_or_within

MGI:97168 (MGI:3723565|PMID:17693062)

PMID:17693062

MGI:3723565

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

odd-skipped related transciption factor 2

involved_in

GO_REF:0000024
(MGI:3818159|PMID:17547533)

PMID:17547533

GO_REF:0000024 MGI:3818159

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

Pappa2

pappalysin 2

acts_upstream_of_or_within

MGI:5504500 (MGI:5502277|PMID:23457539)

PMID:23457539

MGI:5502277

NCBI chr13:70,873,918...71,147,874
Ensembl chr13:70,876,794...71,147,779

Pax1

paired box 1

acts_upstream_of_or_within

MGI:1856223|MGI:1856225 (MGI:69019|PMID:7607069)

PMID:7607069

MGI:69019

NCBI chr 3:134,789,291...134,801,636
Ensembl chr 3:134,789,182...134,801,636

Rarg

retinoic acid receptor, gamma

acts_upstream_of_or_within

MGI:1931079|MGI:88360 (MGI:2154839|PMID:11784046), (MGI:60925|PMID:8388780)

PMID:8388780 PMID:11784046

MGI:2154839 MGI:60925

NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177

Ripply1

ripply transcriptional repressor 1

acts_upstream_of_or_within

MGI:2685968|MGI:4459309 (MGI:4459001|PMID:20346937)

PMID:20346937

MGI:4459001

NCBI chr X:103,436,731...103,440,904
Ensembl chr X:103,436,729...103,443,349

Ripply2

ripply transcriptional repressor 2

acts_upstream_of_or_within

MGI:3614797 (MGI:4459001|PMID:20346937)

PMID:20346937

MGI:4459001

NCBI chr 8:87,974,444...87,978,996
Ensembl chr 8:87,974,776...87,978,969

Sfrp4

secreted frizzled-related protein 4

involved_in

ISO
IEA
ISS

(PMID:27355534)
(MGI:5790095|PMID:27355534)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
UniProt

PMID:27355534

GO_REF:0000024 GO_REF:0000107 MGI:5790095

NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736

Ski

Ski proto-oncogene

acts_upstream_of_or_within

MGI:2177555 (MGI:1095997|PMID:9284043)

PMID:9284043

MGI:1095997

NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733

Sp5

Sp5 transcription factor

acts_upstream_of_or_within

MGI:98472 (MGI:1927252|PMID:11071760)

PMID:11071760

MGI:1927252

NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733

Tbxt

T-box transcription factor T

acts_upstream_of_or_within

MGI:1927715 (MGI:1927252|PMID:11071760)

PMID:11071760

MGI:1927252

NCBI chr 1:52,298,099...52,309,813
Ensembl chr 1:52,298,099...52,305,864

Tfap2a

transcription factor AP-2 alpha

involved_in

GO_REF:0000024
(MGI:80519|PMID:8622766)

PMID:8622766

GO_REF:0000024 MGI:80519

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

bone trabecula formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

collagen type I alpha 1 chain

acts_upstream_of_or_within

MGI:97009 (MGI:3710444|PMID:17440987)

MGI:3710444

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

MGI:1857079 (MGI:5661140|PMID:22359666)

PMID:22359666

MGI:5661140

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

Fbn2

fibrillin 2

involved_in

(MGI:4836762|PMID:20855508)

PMID:20855508

MGI:4836762

NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976

Mmp2

matrix metallopeptidase 2

acts_upstream_of_or_within
involved_in

MGI:88467 (MGI:3710444|PMID:17440987)
GO_REF:0000107

GO_REF:0000107 MGI:3710444

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

Msx2

msh homeobox 2

acts_upstream_of_or_within
involved_in

MGI:1926381 (MGI:1355063|PMID:10742104)
GO_REF:0000107

PMID:10742104

GO_REF:0000107 MGI:1355063

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

Ppargc1b

PPARG coactivator 1 beta

involved_in

(MGI:3838421|PMID:19252502)

PMID:19252502

MGI:3838421

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

Sfrp1

secreted frizzled-related protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3045799 (MGI:3040721|PMID:14976225)

PMID:14976225

GO_REF:0000107 MGI:3040721

NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286

Thbs3

thrombospondin 3

acts_upstream_of_or_within

MGI:3581964 (MGI:3581317|PMID:15964815)

PMID:15964815

MGI:3581317

NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594

Vegfa

vascular endothelial growth factor A

acts_upstream_of_or_within

MGI:1931048 (MGI:5461755|PMID:22886301)

PMID:22886301

MGI:5461755

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Wnt10b

Wnt family member 10B

acts_upstream_of_or_within

MGI:3582610 (MGI:3574150|PMID:15728361)

PMID:15728361

MGI:3574150

NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892

cartilage condensation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acan

aggrecan

acts_upstream_of_or_within
involved_in

MGI:1856465 (MGI:2664273|PMID:3070812)
GO_REF:0000107

PMID:3070812

GO_REF:0000107 MGI:2664273

NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627

Barx2

BARX homeobox 2

acts_upstream_of_or_within

(MGI:3578585|PMID:15800003)

PMID:15800003

MGI:3578585

NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013

Bmpr1b

bone morphogenetic protein receptor type 1B

acts_upstream_of_or_within

MGI:2158498 (MGI:1351297|PMID:10631181)

PMID:10631181

MGI:1351297

NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368

Ccn2

cellular communication network factor 2

acts_upstream_of_or_within

(MGI:3050271|PMID:15305294)

PMID:15305294

MGI:3050271

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

chondroadherin

RGD

NCBI chr10:79,512,170...79,515,941
Ensembl chr10:79,511,931...79,515,940

Col11a1

collagen type XI alpha 1 chain

acts_upstream_of_or_within

MGI:1856399 (MGI:2664273|PMID:3070812)

PMID:3070812

MGI:2664273

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

collagen type II alpha 1 chain

acts_upstream_of_or_within

MGI:1857275 (MGI:2664273|PMID:3070812)

PMID:3070812

MGI:2664273

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Fgf4

fibroblast growth factor 4

acts_upstream_of_or_within

MGI:98726 (MGI:78390|PMID:8565825)

NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466

Fgf6

fibroblast growth factor 6

acts_upstream_of_or_within

MGI:98726 (MGI:78390|PMID:8565825)

NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447

Mapk14

mitogen activated protein kinase 14

involved_in

GO_REF:0000107
(MGI:5487758|PMID:17202865)

PMID:17202865

GO_REF:0000107 MGI:5487758

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

Mycn

MYCN proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

(MGI:3790402|PMID:17360777)

PMID:17360777

MGI:3790402

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

Myf5

myogenic factor 5

acts_upstream_of_or_within

MGI:1857219 (MGI:78390|PMID:8565825)

NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177

Otor

otoraplin

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:1928405|PMID:10998416)

PMID:10998416 PMID:21873635

MGI:1928405, RGD:13792537

NCBI chr 3:130,415,339...130,418,601
Ensembl chr 3:130,415,339...130,418,601

Pkd1

polycystin 1, transient receptor potential channel interacting

acts_upstream_of_or_within

MGI:2152589 (MGI:2152028|PMID:11593033)

PMID:11593033

MGI:2152028

NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128

Ror2

receptor tyrosine kinase-like orphan receptor 2

acts_upstream_of_or_within

MGI:2183225 (MGI:3037488|PMID:14745966)

PMID:14745966

MGI:3037488

NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152

Sox5

SRY-box transcription factor 5

involved_in

GO_REF:0000024
(MGI:2446758|PMID:11702786), (MGI:3037234|PMID:14993235)

PMID:11702786 PMID:14993235

GO_REF:0000024 MGI:2446758 MGI:3037234

NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852

Sox6

SRY-box transcription factor 6

involved_in

GO_REF:0000024
(MGI:2446758|PMID:11702786), (MGI:3037234|PMID:14993235)

PMID:11702786 PMID:14993235

GO_REF:0000024 MGI:2446758 MGI:3037234

NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386

SRY-box transcription factor 9

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:2158693|MGI:2385468 (MGI:2159578|PMID:10319868), (MGI:2389523|PMID:12414734)

PMID:10319868 PMID:12414734

GO_REF:0000024 MGI:2159578 MGI:2389523

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

Sulf1

sulfatase 1

involved_in

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584

Tgfb2

transforming growth factor, beta 2

acts_upstream_of_or_within

MGI:95518|MGI:95520 (MGI:78390|PMID:8565825)

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Thra

thyroid hormone receptor alpha

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1860442 (MGI:894529|PMID:9250685)

PMID:9250685

GO_REF:0000107 MGI:894529

NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936

Uncx

UNC homeobox

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1859373|MGI:1928812 (MGI:1855901|PMID:10804169), (MGI:1855902|PMID:10804168)

PMID:10804168 PMID:10804169

GO_REF:0000107 MGI:1855901 MGI:1855902

NCBI chr12:15,092,779...15,097,300
Ensembl chr12:15,092,784...15,097,300

Wnt7a

Wnt family member 7A

involved_in

(PMID:17202865)

PMID:17202865

NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981

cartilage development involved in endochondral bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbs

cystathionine beta synthase

acts_upstream_of_or_within

MGI:1857139 (MGI:3656462|PMID:15622513)

PMID:15622513

MGI:3656462

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

collagen type I alpha 1 chain

acts_upstream_of_or_within

MGI:3769585 (MGI:3769669|PMID:18248096)

PMID:18248096

MGI:3769669

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

collagen type II alpha 1 chain

acts_upstream_of_or_within

IEP
ISO

mandibular condylar cartilage
MGI:1857275|MGI:2152978 (MGI:3697977|PMID:11680679), (MGI:84914|PMID:8989518), (MGI:85592|PMID:9022054)

PMID:8989518 PMID:9022054 PMID:11680679 PMID:12924823

MGI:3697977 MGI:84914 MGI:85592, RGD:8661659

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

exostosin glycosyltransferase 1

acts_upstream_of_or_within

(MGI:4946896|PMID:21185280), (MGI:5528913|PMID:23958822)

PMID:21185280 PMID:23958822

MGI:4946896 MGI:5528913

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

Ghr

growth hormone receptor

RGD

PMID:15749813

RGD:2307373

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

Hoxa11

homeobox A11

acts_upstream_of_or_within

MGI:96203 (MGI:3043491|PMID:14668414)

PMID:14668414

MGI:3043491

NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232

Hoxd11

homeobox D11

acts_upstream_of_or_within

MGI:96172 (MGI:3043491|PMID:14668414)

PMID:14668414

MGI:3043491

NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783

Hspg2

heparan sulfate proteoglycan 2

acts_upstream_of_or_within

MGI:1934891 (MGI:1930356|PMID:10545953)

PMID:10545953

MGI:1930356

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

Shox2

short stature homeobox 2

acts_upstream_of_or_within
involved_in

MGI:3628798 (MGI:3621617|PMID:16537395)
GO_REF:0000107

PMID:16537395

GO_REF:0000107 MGI:3621617

NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143

Sik3

SIK family kinase 3

acts_upstream_of_or_within

MGI:5317918 (MGI:5316542|PMID:22318228)

PMID:22318228

MGI:5316542

NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444

Trpv4

transient receptor potential cation channel, subfamily V, member 4

involved_in

(PMID:26249260)

PMID:26249260

NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517

chondrocyte development involved in endochondral bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Serpinh1

serpin family H member 1

acts_upstream_of_or_within
involved_in

MGI:2176070|MGI:5505265 (MGI:5494537|PMID:22492985)
GO_REF:0000107

PMID:22492985

GO_REF:0000107 MGI:5494537

NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801

Smpd3

sphingomyelin phosphodiesterase 3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856877 (MGI:5293259|PMID:21788370)

PMID:21788370

GO_REF:0000107 MGI:5293259

NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749

chondrocyte differentiation involved in endochondral bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Axin2

axin 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)

PMID:19623616

GO_REF:0000107 MGI:4818263

NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231

Ihh

Indian hedgehog signaling molecule

acts_upstream_of_or_within

(MGI:5698232|PMID:25639508)

PMID:25639508

MGI:5698232

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

Scube2

signal peptide, CUB domain and EGF like domain containing 2

acts_upstream_of_or_within

MGI:5698367 (MGI:5698232|PMID:25639508)

PMID:25639508

MGI:5698232

NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393

SRY-box transcription factor 9

involved_in

GO_REF:0000024
(PMID:20676705)

PMID:20676705

GO_REF:0000024

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

Trip11

thyroid hormone receptor interactor 11

acts_upstream_of_or_within

MGI:4829605 (MGI:4822550|PMID:20089971)

PMID:20089971

MGI:4822550

NCBI chr 6:120,995,242...121,067,693
Ensembl chr 6:120,998,733...121,067,781

coronal suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fgfr2

fibroblast growth factor receptor 2

acts_upstream_of_or_within

MGI:3603464 (MGI:3848571|PMID:19389359)

PMID:19389359

MGI:3848571

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

cranial suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone morphogenetic protein 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:1203304|PMID:9477322)

PMID:9477322

GO_REF:0000107 MGI:1203304

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Fgf4

fibroblast growth factor 4

acts_upstream_of_or_within

(MGI:1203304|PMID:9477322)

PMID:9477322

MGI:1203304

NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466

Igf1

insulin-like growth factor 1

RGD

PMID:10597685

RGD:12910129

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

Insig1

insulin induced gene 1

acts_upstream_of_or_within

MGI:1920249 (MGI:3689278|PMID:16955138)

PMID:16955138

MGI:3689278

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

Insig2

insulin induced gene 2

acts_upstream_of_or_within

MGI:1916289 (MGI:3689278|PMID:16955138)

PMID:16955138

MGI:3689278

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

Twist1

twist family bHLH transcription factor 1

acts_upstream_of_or_within
involved_in

MGI:1857265|MGI:3038818 (MGI:2387743|PMID:12221714), (MGI:3042355|PMID:15030764)
(MGI:3623529|PMID:16502419)

PMID:12221714 PMID:15030764 PMID:16502419

MGI:2387743 MGI:3042355 MGI:3623529

NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653

craniofacial suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxn3

forkhead box N3

acts_upstream_of_or_within

(MGI:4835344|PMID:20691664)

PMID:20691664

MGI:4835344

NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401

Frem1

Fras1 related extracellular matrix 1

involved_in

(PMID:21931569)

PMID:21931569

NCBI chr 5:97,321,275...97,469,523
Ensembl chr 5:97,322,538...97,469,543

Megf8

multiple EGF-like-domains 8

involved_in

GO_REF:0000107
(PMID:23063620)

PMID:23063620

GO_REF:0000107

NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613

Mmp14

matrix metallopeptidase 14

acts_upstream_of_or_within

MGI:1276107 (MGI:3771253|PMID:18022611)

MGI:3771253

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

Mmp16

matrix metallopeptidase 16

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:101900 (MGI:3771253|PMID:18022611)

GO_REF:0000107 MGI:3771253

NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388

Neurog1

neurogenin 1

involved_in

UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067)

PMID:23419067

NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571

Rab23

RAB23, member RAS oncogene family

involved_in

(PMID:17503333)

PMID:17503333

NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927

Tifab

TIFA inhibitor

involved_in

UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067)

PMID:23419067

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

Tmem107

transmembrane protein 107

acts_upstream_of_or_within

MGI:5007367 (MGI:6115041|PMID:28954202)

PMID:28954202

MGI:6115041

NCBI chr10:53,772,153...53,774,685
Ensembl chr10:53,771,784...53,774,676

embryonic cranial skeleton morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone morphogenetic protein 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857137 (MGI:1095762|PMID:9268572)

PMID:9268572

GO_REF:0000107 MGI:1095762

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Dlx2

distal-less homeobox 2

acts_upstream_of_or_within
involved_in

MGI:1857828 (MGI:76977|PMID:7590232)
GO_REF:0000107

PMID:7590232

GO_REF:0000107 MGI:76977

NCBI chr 3:56,371,347...56,373,230
Ensembl chr 3:56,370,483...56,373,597

Eif4a3

eukaryotic translation initiation factor 4A3

involved_in

GO_REF:0000024
(PMID:24360810)

PMID:24360810

GO_REF:0000024

NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057

Fgfr2

fibroblast growth factor receptor 2

involved_in

(PMID:7874170), (PMID:7987400)

PMID:7874170 PMID:7987400

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

Foxc2

forkhead box C2

acts_upstream_of_or_within

MGI:1857865 (MGI:86990|PMID:9106663)

PMID:9106663

MGI:86990

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

Gas1

growth arrest-specific 1

acts_upstream_of_or_within

MGI:2388397|MGI:98297 (MGI:3713422|PMID:17525797)

PMID:17525797

MGI:3713422

NCBI chr17:4,482,014...4,485,155

Gnas

GNAS complex locus

acts_upstream_of_or_within

MGI:3043361 (MGI:3619837|PMID:15797856)

PMID:15797856

MGI:3619837

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

Grhl2

grainyhead-like transcription factor 2

acts_upstream_of_or_within

MGI:4942413 (MGI:4943100|PMID:21377456)

PMID:21377456

MGI:4943100

NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258

Ift140

intraflagellar transport 140

acts_upstream_of_or_within

MGI:4458412 (MGI:5505384|PMID:23469164)

PMID:23469164

MGI:5505384

NCBI chr10:14,032,665...14,121,682
Ensembl chr10:14,032,648...14,120,433

Irx5

iroquois homeobox 5

involved_in

(PMID:22581230)

PMID:22581230

NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318

Mmp14

matrix metallopeptidase 14

acts_upstream_of_or_within

MGI:1276107 (MGI:3771253|PMID:18022611)

MGI:3771253

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

Mmp16

matrix metallopeptidase 16

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:101900 (MGI:3771253|PMID:18022611)

GO_REF:0000107 MGI:3771253

NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388

Nipbl

NIPBL, cohesin loading factor

acts_upstream_of_or_within

MGI:4332250 (MGI:4367301|PMID:19763162)

PMID:19763162

MGI:4367301

NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899

Nodal

nodal growth differentiation factor

acts_upstream_of_or_within

MGI:2158732 (MGI:2155575|PMID:11311163)

PMID:11311163

MGI:2155575

NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837

Pax5

paired box 5

acts_upstream_of_or_within

MGI:2386577 (MGI:5476374|PMID:23349049)

PMID:9226440 PMID:21873635

PMID:23349049

MGI:5476374

NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326

Pdgfra

platelet derived growth factor receptor alpha

involved_in

ISO
IEA
IBA
ISS

(MGI:894516|PMID:9226440)
GO_REF:0000107
PMID:21873635
GO_REF:0000024

RGD
Ensembl
UniProt

GO_REF:0000024 GO_REF:0000107 MGI:894516, RGD:13792537

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Prrx1

paired related homeobox 1

acts_upstream_of_or_within

MGI:1857640|MGI:98218 (MGI:1306737|PMID:9729491), (MGI:73363|PMID:7758948)

PMID:7758948 PMID:9729491

MGI:1306737 MGI:73363

NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866

Prrx2

paired related homeobox 2

acts_upstream_of_or_within

MGI:97712 (MGI:1306737|PMID:9729491)

PMID:9729491

MGI:1306737

NCBI chr 3:14,132,511...14,168,535
Ensembl chr 3:14,094,004...14,168,535

Runx2

RUNX family transcription factor 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:104685|MGI:98872 (MGI:3042355|PMID:15030764)

GO_REF:0000107 MGI:3042355

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

Setd2

SET domain containing 2, histone lysine methyltransferase

acts_upstream_of_or_within

MGI:4437211 (MGI:4431136|PMID:20133625)

PMID:20133625

MGI:4431136

NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489

Six1

SIX homeobox 1

acts_upstream_of_or_within

MGI:106034 (MGI:4822095|PMID:20515681)

PMID:20515681

MGI:4822095

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Six2

SIX homeobox 2

acts_upstream_of_or_within

MGI:3691857 (MGI:4822095|PMID:20515681)

PMID:20515681

MGI:4822095

NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193

Six4

SIX homeobox 4

acts_upstream_of_or_within

MGI:102780 (MGI:4822095|PMID:20515681)

PMID:20515681

MGI:4822095

NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992

Slc39a1

solute carrier family 39 member 1

acts_upstream_of_or_within

MGI:2147269|MGI:3625131 (MGI:3624433|PMID:16652366)

PMID:16652366

MGI:3624433

NCBI chr 2:175,703,413...175,709,063
Ensembl chr 2:175,703,441...175,709,058

Slc39a3

solute carrier family 39 member 3

acts_upstream_of_or_within

MGI:1353474 (MGI:3624433|PMID:16652366)

PMID:16652366

MGI:3624433

NCBI chr 7:8,676,845...8,682,846
Ensembl chr 7:8,676,759...8,685,149

Smad2

SMAD family member 2

acts_upstream_of_or_within

MGI:1201674 (MGI:3618021|PMID:15183723)

PMID:15183723

MGI:3618021

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

Smad3

SMAD family member 3

acts_upstream_of_or_within

MGI:108051 (MGI:3618021|PMID:15183723)

PMID:15183723

MGI:3618021

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

Tbx1

T-box transcription factor 1

acts_upstream_of_or_within
involved_in

MGI:2179191 (MGI:3050165|PMID:15190012)
GO_REF:0000024

PMID:15190012

GO_REF:0000024 MGI:3050165

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

Tbx15

T-box transcription factor 15

acts_upstream_of_or_within

MGI:1856015 (MGI:3604843|PMID:15728667)

PMID:15728667

MGI:3604843

NCBI chr 2:186,576,347...186,687,748
Ensembl chr 2:186,576,676...186,687,663

Tfap2a

transcription factor AP-2 alpha

acts_upstream_of_or_within
involved_in

MGI:1888387 (MGI:80520|PMID:8622765)
GO_REF:0000024
(MGI:80519|PMID:8622766)

PMID:8622765 PMID:8622766

GO_REF:0000024 MGI:80519 MGI:80520

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

Tgfbr1

transforming growth factor, beta receptor 1

acts_upstream_of_or_within

MGI:2680164 (MGI:3701721|PMID:16806156)

PMID:16806156

MGI:3701721

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

Tgfbr2

transforming growth factor, beta receptor 2

involved_in

(MGI:2678274|PMID:12975342)

PMID:12975342

MGI:2678274

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

Twist1

twist family bHLH transcription factor 1

acts_upstream_of_or_within
involved_in

MGI:99829 (MGI:3042355|PMID:15030764)
(PMID:8988166), (PMID:8988167)
(MGI:1100098|PMID:8988167)

PMID:8988166 PMID:8988167 PMID:15030764

MGI:1100098 MGI:3042355

NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653

Twist2

twist family bHLH transcription factor 2

acts_upstream_of_or_within

MGI:99829 (MGI:3042355|PMID:15030764)

MGI:3042355

NCBI chr 9:92,374,740...92,419,222
Ensembl chr 9:92,374,574...92,419,222

Wdr19

WD repeat domain 19

acts_upstream_of_or_within

MGI:5315747 (MGI:5314316|PMID:22228095)

PMID:22228095

MGI:5314316

NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288

Wnt9b

Wnt family member 9B

acts_upstream_of_or_within

MGI:1856821|MGI:3526437 (MGI:3588895|PMID:16054034), (MGI:3696935|PMID:16998816)

PMID:16054034 PMID:16998816

MGI:3588895 MGI:3696935

NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035

embryonic neurocranium morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fgf8

fibroblast growth factor 8

acts_upstream_of_or_within

MGI:1917550 (MGI:5796907|PMID:27395007)

PMID:27395007

MGI:5796907

NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359

Fuz

fuzzy planar cell polarity protein

acts_upstream_of_or_within

MGI:3531090|MGI:99604 (MGI:5796907|PMID:27395007)

PMID:27395007

MGI:5796907

NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:5796907|PMID:27395007)

PMID:27395007

MGI:5796907

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

Hoxa1

homeobox A1

involved_in

(PMID:16155570)

PMID:16155570

NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504

Med12

mediator complex subunit 12

acts_upstream_of_or_within

MGI:4839485 (MGI:4839544|PMID:20589884)

PMID:20589884

MGI:4839544

NCBI chr X:66,404,622...66,427,772
Ensembl chr X:66,404,760...66,428,387

Mthfd1l

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

involved_in

(MGI:5468075|PMID:23267094)

PMID:23267094

MGI:5468075

NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905

Ndst1

N-deacetylase and N-sulfotransferase 1

acts_upstream_of_or_within

MGI:3589383 (MGI:3588476|PMID:16020517)

PMID:16020517

MGI:3588476

NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191

Tgfb2

transforming growth factor, beta 2

IDA

RGD

PMID:11002343

RGD:1579866

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tgfb3

transforming growth factor, beta 3

IDA

RGD

PMID:11002343

RGD:1579866

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

Tulp3

TUB like protein 3

acts_upstream_of_or_within

MGI:2388066 (MGI:3841503|PMID:19286674)

PMID:19286674

MGI:3841503

NCBI chr 4:161,590,478...161,632,514
Ensembl chr 4:161,590,479...161,632,149

embryonic skeletal joint morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Axin1

axin 1

acts_upstream_of_or_within

MGI:1856035|MGI:1856036

MGI:48782

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

bone morphogenetic protein 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:103302|MGI:1857137 (MGI:1270933|PMID:9664686)

PMID:9664686

GO_REF:0000107 MGI:1270933

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Bmp7

bone morphogenetic protein 7

acts_upstream_of_or_within

MGI:1934010|MGI:88180 (MGI:1270933|PMID:9664686)

PMID:9664686

MGI:1270933

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

collagen type II alpha 1 chain

involved_in

(PMID:16752401)

PMID:16752401

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Hoxa11

homeobox A11

acts_upstream_of_or_within

MGI:96193|MGI:96203 (MGI:4867119|PMID:20978074)

PMID:20978074

MGI:4867119

NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232

Hoxc11

homeobox C11

acts_upstream_of_or_within

MGI:96172|MGI:96203 (MGI:4867119|PMID:20978074)

PMID:20978074

MGI:4867119

NCBI chr 7:134,091,224...134,094,738
Ensembl chr 7:134,091,552...134,094,738

Hoxd11

homeobox D11

acts_upstream_of_or_within

MGI:96172|MGI:96193 (MGI:4867119|PMID:20978074)

PMID:20978074

MGI:4867119

NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783

Hyal1

hyaluronidase 1

acts_upstream_of_or_within

MGI:2658730 (MGI:3836537|PMID:18772348)

PMID:18772348

MGI:3836537

NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210

Nog

noggin

involved_in

GO_REF:0000107
(PMID:16151340)

PMID:16151340

GO_REF:0000107

NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339

Osr1

odd-skipped related transcription factor 1

involved_in

UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216)

NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817

odd-skipped related transciption factor 2

involved_in

(MGI:4950000|PMID:21262216)

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

Shox2

short stature homeobox 2

acts_upstream_of_or_within
involved_in

MGI:3626291 (MGI:3805084|PMID:18514492)
GO_REF:0000107

PMID:18514492

GO_REF:0000107 MGI:3805084

NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143

embryonic skeletal limb joint morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctnnb1

catenin beta 1

involved_in

GO_REF:0000107
UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216)

GO_REF:0000107 MGI:4950000

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

Osr1

odd-skipped related transcription factor 1

involved_in

UniProtKB:Q91ZD1 (MGI:4950000|PMID:21262216)

NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817

odd-skipped related transciption factor 2

involved_in

UniProtKB:Q9WVG7 (MGI:4950000|PMID:21262216)

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

embryonic skeletal system morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alx1

ALX homeobox 1

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:108359 (MGI:1314705|PMID:9847249), (MGI:3604843|PMID:15728667)

PMID:9847249 PMID:15728667 PMID:21873635

MGI:1314705 MGI:3604843, RGD:13792537

NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220

Alx3

ALX homeobox 3

acts_upstream_of_or_within

MGI:108359 (MGI:2151109|PMID:11641221), (MGI:3604843|PMID:15728667)

PMID:11641221 PMID:15728667

MGI:2151109 MGI:3604843

NCBI chr 2:195,231,197...195,241,609
Ensembl chr 2:195,231,197...195,241,609

Alx4

ALX homeobox 4

acts_upstream_of_or_within

PMID:9847249 PMID:11641221 PMID:15728667

MGI:1314705 MGI:2151109 MGI:3604843

NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260

Asxl2

ASXL transcriptional regulator 2

acts_upstream_of_or_within

MGI:3840841 (MGI:3840399|PMID:19270745)

PMID:19270745

MGI:3840399

NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477

Bmi1

BMI1 proto-oncogene, polycomb ring finger

acts_upstream_of_or_within

MGI:99161 (MGI:1932296|PMID:11290297)

PMID:11290297

MGI:1932296

NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690

bone morphogenetic protein 4

acts_upstream_of_or_within

MGI:2158495 (MGI:3640733|PMID:16712836)

PMID:16712836

MGI:3640733

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Chst11

carbohydrate sulfotransferase 11

acts_upstream_of_or_within

MGI:3768254 (MGI:3767479|PMID:16079159)

PMID:16079159

MGI:3767479

NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111

Col11a1

collagen type XI alpha 1 chain

acts_upstream_of_or_within

MGI:1856399 (MGI:53676|PMID:4100752)

PMID:4100752

MGI:53676

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

Dlg1

discs large MAGUK scaffold protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2680670 (MGI:1930428|PMID:11238884)

PMID:11238884

GO_REF:0000107 MGI:1930428

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

Dscaml1

DS cell adhesion molecule-like 1

involved_in

(PMID:12051741)

PMID:12051741

NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320

Dync2i1

dynein 2 intermediate chain 1

involved_in

(PMID:23910462)

PMID:23910462

NCBI chr 6:137,133,418...137,189,937
Ensembl chr 6:137,133,418...137,188,719

Eya1

EYA transcriptional coactivator and phosphatase 1

acts_upstream_of_or_within

MGI:2150426 (MGI:1344210|PMID:10471511)

PMID:10471511

MGI:1344210

NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483

Flvcr1

FLVCR heme transporter 1

acts_upstream_of_or_within

MGI:5474636 (MGI:5471193|PMID:23187127)

PMID:23187127

MGI:5471193

NCBI chr13:102,586,263...102,608,647
Ensembl chr13:102,586,257...102,608,661

Foxc2

forkhead box C2

acts_upstream_of_or_within

MGI:1857740 (MGI:1339313|PMID:9409679)

PMID:9409679

MGI:1339313

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

Fuz

fuzzy planar cell polarity protein

involved_in

(MGI:4438317|PMID:19767740), (MGI:5296432|PMID:21935430), (MGI:5498583|PMID:23806618)
GO_REF:0000024

PMID:19767740 PMID:21935430 PMID:23806618

GO_REF:0000024 MGI:4438317 MGI:5296432 MGI:5498583

NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1277234 (MGI:3604843|PMID:15728667)

PMID:15728667

MGI:3604843

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

Gsc

goosecoid homeobox

acts_upstream_of_or_within

MGI:1857496|MGI:1857726 (MGI:76246|PMID:7555726), (MGI:76955|PMID:7555718)

PMID:7555718 PMID:7555726

MGI:76246 MGI:76955

NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111

Hoxa2

homeobox A2

acts_upstream_of_or_within

MGI:102778 (MGI:3525808|PMID:15634706)

PMID:15634706

MGI:3525808

Ensembl chr 4:81,262,768...81,265,044

Hoxa3

homeobox A3

acts_upstream_of_or_within
involved_in

MGI:96184|MGI:96207 (MGI:1195045|PMID:9441667)
PMID:21873635

PMID:9441667 PMID:21873635

MGI:1195045, RGD:13792537

NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218

Hoxa4

homeo box A4

acts_upstream_of_or_within

MGI:2150391|MGI:96185|MGI:96208 (MGI:67413|PMID:7918106), (MGI:74948|PMID:7628700)

PMID:7628700 PMID:7918106

MGI:67413 MGI:74948

NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:81,289,682...81,291,685

Hoxa5

homeo box A5

acts_upstream_of_or_within

MGI:2150397|MGI:3723623 (MGI:1203259|PMID:9603431), (MGI:3723390|PMID:17417799), (MGI:63693|PMID:7901120)

PMID:7901120 PMID:9603431 PMID:17417799

MGI:1203259 MGI:3723390 MGI:63693

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

Hoxa7

homeobox A7

acts_upstream_of_or_within
involved_in

MGI:96188 (MGI:1313067|PMID:9784603)
GO_REF:0000107

PMID:9784603

GO_REF:0000107 MGI:1313067

NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659

Hoxa9

homeobox A9

involved_in

IBA

PMID:21873635

GO_Central

PMID:21873635

NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358

Hoxb1

homeo box B1

acts_upstream_of_or_within

MGI:96183|MGI:96184|MGI:96185|MGI:96186|MGI:96187|MGI:96188|MGI:96189|MGI:96190 (MGI:1859107|PMID:10885747)

PMID:10885747

MGI:1859107

NCBI chr10:81,331,507...81,332,928
Ensembl chr10:81,331,507...81,332,836

Hoxb2

homeobox B2

acts_upstream_of_or_within

MGI:96182|MGI:96184|MGI:96185|MGI:96186|MGI:96187|MGI:96188|MGI:96189|MGI:96190 (MGI:1859107|PMID:10885747)

PMID:10885747

MGI:1859107

NCBI chr10:81,317,927...81,320,223
Ensembl chr10:81,318,026...81,320,192

Hoxb3

homeo box B3

acts_upstream_of_or_within
involved_in

MGI:2151773|MGI:96175|MGI:96182|MGI:96183|MGI:96185|MGI:96186|MGI:96187|MGI:96188|MGI:96189|MGI:96190|MGI:96207 (MGI:1195045|PMID:9441667), (MGI:1859107|PMID:10885747)
PMID:21873635

PMID:9441667 PMID:10885747 PMID:21873635

MGI:1195045 MGI:1859107, RGD:13792537

NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107

Hoxb4

homeo box B4

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:96176|MGI:96183|MGI:96184|MGI:96186|MGI:96187|MGI:96188|MGI:96189|MGI:96190 (MGI:1859107|PMID:10885747), (MGI:74948|PMID:7628700)

PMID:7628700 PMID:10885747 PMID:21873635

MGI:1859107 MGI:74948, RGD:13792537

NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128

Hoxb5

homeo box B5

acts_upstream_of_or_within

MGI:96182|MGI:96183|MGI:96184|MGI:96185|MGI:96187|MGI:96188|MGI:96189|MGI:96190 (MGI:1859107|PMID:10885747), (MGI:70296|PMID:7828847)

PMID:7828847 PMID:10885747

MGI:1859107 MGI:70296

NCBI chr10:81,269,372...81,271,580
Ensembl chr10:81,269,372...81,271,580

Hoxb6

homeo box B6

acts_upstream_of_or_within

MGI:96182|MGI:96183|MGI:96184|MGI:96185|MGI:96186|MGI:96188|MGI:96189|MGI:96190 (MGI:1859107|PMID:10885747)

PMID:10885747

MGI:1859107

NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449

Hoxb7

homeo box B7

acts_upstream_of_or_within

MGI:2150401|MGI:96179|MGI:96182|MGI:96183|MGI:96184|MGI:96185|MGI:96186|MGI:96187|MGI:96189|MGI:96190 (MGI:1313067|PMID:9784603), (MGI:1859107|PMID:10885747)

PMID:9784603 PMID:10885747

MGI:1313067 MGI:1859107

NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034

Hoxb8

homeo box B8

acts_upstream_of_or_within
involved_in

MGI:1934178|MGI:96182|MGI:96183|MGI:96184|MGI:96185|MGI:96186|MGI:96187|MGI:96188|MGI:96190 (MGI:1349283|PMID:10559485), (MGI:1859107|PMID:10885747)
GO_REF:0000107

PMID:10559485 PMID:10885747

GO_REF:0000107 MGI:1349283 MGI:1859107

NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638

Hoxb9

homeo box B9

involved_in

IBA

PMID:21873635

GO_Central

PMID:21873635

NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818

Hoxc9

homeobox C9

acts_upstream_of_or_within

MGI:2150685 (MGI:73980|PMID:7547473)

PMID:7547473

MGI:73980

NCBI chr 7:134,118,817...134,121,497
Ensembl chr 7:134,118,817...134,121,492

Hoxd10

homeo box D10

acts_upstream_of_or_within

MGI:96210 (MGI:1350864|PMID:10642795)

PMID:10642795

MGI:1350864

NCBI chr 3:59,594,516...59,597,725
Ensembl chr 3:59,594,516...59,597,725

Hoxd3

homeo box D3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857959|MGI:96175 (MGI:63793|PMID:7910549), (MGI:67616|PMID:7913519)

PMID:7910549 PMID:7913519

GO_REF:0000107 MGI:63793 MGI:67616

NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282

Hoxd4

homeo box D4

acts_upstream_of_or_within
involved_in

MGI:2151488|MGI:96176 (MGI:72992|PMID:7750651), (MGI:74948|PMID:7628700)
PMID:21873635

PMID:7628700 PMID:7750651 PMID:21873635

MGI:72992 MGI:74948, RGD:13792537

NCBI chr 3:59,614,464...59,634,042
Ensembl chr 3:59,614,464...59,631,528

Hoxd9

homeo box D9

involved_in
acts_upstream_of_or_within

IBA
ISO
IEA

PMID:21873635
MGI:96202 (MGI:1350864|PMID:10642795)
GO_REF:0000107

PMID:10642795 PMID:21873635

GO_REF:0000107 MGI:1350864, RGD:13792537

NCBI chr 3:59,600,575...59,602,755
Ensembl chr 3:59,600,575...59,602,754

Hspg2

heparan sulfate proteoglycan 2

acts_upstream_of_or_within

MGI:1934892 (MGI:1349497|PMID:10579729)

PMID:10579729

MGI:1349497

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

Mdfi

MyoD family inhibitor

acts_upstream_of_or_within

MGI:2155446 (MGI:1312999|PMID:9799236)

PMID:9799236

MGI:1312999

NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217

Mef2c

myocyte enhancer factor 2C

acts_upstream_of_or_within

MGI:3603182 (MGI:3714538|PMID:17420000)

PMID:17420000

MGI:3714538

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Megf8

multiple EGF-like-domains 8

involved_in

ISO
IEA
ISS

(MGI:5551355|PMID:24052814)
GO_REF:0000107
GO_REF:0000024

RGD
Ensembl
CAFA

PMID:24052814

GO_REF:0000024 GO_REF:0000107 MGI:5551355

NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613

Men1

menin 1

acts_upstream_of_or_within

MGI:2683274|MGI:3573783 (MGI:3763871|PMID:17927973)

PMID:17927973

MGI:3763871

NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871

Mycn

MYCN proto-oncogene, bHLH transcription factor

acts_upstream_of_or_within

(MGI:3790402|PMID:17360777)

PMID:17360777

MGI:3790402

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

Myf5

myogenic factor 5

acts_upstream_of_or_within

MGI:1857219 (MGI:1861090|PMID:10929709)

PMID:10929709

MGI:1861090

NCBI chr 7:42,802,946...42,806,177
Ensembl chr 7:42,802,946...42,806,177

odd-skipped related transciption factor 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:3033240 (MGI:3513962|PMID:15175245)

PMID:15175245

GO_REF:0000024 MGI:3513962

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

Pcgf2

polycomb group ring finger 2

acts_upstream_of_or_within

MGI:88174 (MGI:1932296|PMID:11290297)

PMID:11290297

MGI:1932296

NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406

Pdgfra

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

Prrx1

paired related homeobox 1

acts_upstream_of_or_within

PMID:7758948 PMID:9729491 PMID:9876178 PMID:11532916

MGI:1306737 MGI:1321048 MGI:2149056 MGI:73363

NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866

Prrx2

paired related homeobox 2

acts_upstream_of_or_within

MGI:97712 (MGI:1306737|PMID:9729491), (MGI:1321048|PMID:9876178), (MGI:2149056|PMID:11532916)

PMID:9729491 PMID:9876178 PMID:11532916

MGI:1306737 MGI:1321048 MGI:2149056

NCBI chr 3:14,132,511...14,168,535
Ensembl chr 3:14,094,004...14,168,535

Satb2

SATB homeobox 2

acts_upstream_of_or_within

MGI:3692768|MGI:3695425 (MGI:3692344|PMID:16751105), (MGI:3695004|PMID:16960803)

PMID:16751105 PMID:16960803

MGI:3692344 MGI:3695004

NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707

Six1

SIX homeobox 1

acts_upstream_of_or_within

MGI:106034 (MGI:3578604|PMID:15788460)

PMID:15788460

MGI:3578604

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

Six2

SIX homeobox 2

acts_upstream_of_or_within

MGI:96174 (MGI:3525808|PMID:15634706)

PMID:15634706

MGI:3525808

NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193

Six4

SIX homeobox 4

acts_upstream_of_or_within

MGI:102780 (MGI:3578604|PMID:15788460)

PMID:15788460

MGI:3578604

NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992

Sox11

SRY-box transcription factor 11

involved_in

GO_REF:0000024
(MGI:3052265|PMID:15254231)

PMID:15254231

GO_REF:0000024 MGI:3052265

NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354

Tbx15

T-box transcription factor 15

acts_upstream_of_or_within

MGI:1856015|MGI:95729 (MGI:3604843|PMID:15728667)

PMID:15728667

MGI:3604843

NCBI chr 2:186,576,347...186,687,748
Ensembl chr 2:186,576,676...186,687,663

Twist1

twist family bHLH transcription factor 1

acts_upstream_of_or_within

MGI:3038818 (MGI:3042355|PMID:15030764)

MGI:3042355

NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653

Wnt9a

Wnt family member 9A

acts_upstream_of_or_within

MGI:3701350 (MGI:3701031|PMID:16818445)

PMID:16818445

MGI:3701031

NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133

Zeb1

zinc finger E-box binding homeobox 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857799 (MGI:1195626|PMID:9389660)

PMID:9389660

GO_REF:0000107 MGI:1195626

NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214

embryonic viscerocranium morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Chst11

carbohydrate sulfotransferase 11

acts_upstream_of_or_within

MGI:3768254 (MGI:3767479|PMID:16079159)

PMID:16079159

MGI:3767479

NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111

Foxc2

forkhead box C2

acts_upstream_of_or_within

MGI:1857740 (MGI:1339313|PMID:9409679)

PMID:9409679

MGI:1339313

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

Hoxa2

homeobox A2

acts_upstream_of_or_within
involved_in

MGI:2385711 (MGI:3608156|PMID:16221728)
GO_REF:0000107

PMID:16221728

GO_REF:0000107 MGI:3608156

Ensembl chr 4:81,262,768...81,265,044

Lhx1

LIM homeobox 1

involved_in

GO_REF:0000024
(MGI:3777712|PMID:14695376)

PMID:14695376

GO_REF:0000024 MGI:3777712

NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617

Mef2c

myocyte enhancer factor 2C

acts_upstream_of_or_within

MGI:3603182 (MGI:3714538|PMID:17420000)

PMID:17420000

MGI:3714538

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Mthfd1l

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

involved_in

(MGI:5468075|PMID:23267094)

PMID:23267094

MGI:5468075

NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905

Ndst1

N-deacetylase and N-sulfotransferase 1

acts_upstream_of_or_within

MGI:3589383 (MGI:3588476|PMID:16020517)

PMID:16020517

MGI:3588476

NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191

Nipbl

NIPBL, cohesin loading factor

involved_in
acts_upstream_of_or_within

PMID:21873635
MGI:4332250 (MGI:4367301|PMID:19763162)

PMID:19763162 PMID:21873635

MGI:4367301, RGD:13792537

NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899

Rdh10

retinol dehydrogenase 10

acts_upstream_of_or_within

(MGI:3709664|PMID:17473173)

PMID:17473173

MGI:3709664

NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572

Tbx1

T-box transcription factor 1

involved_in

GO_REF:0000024
(PMID:14585638)

PMID:14585638

GO_REF:0000024

NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380

endochondral bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bmpr2

bone morphogenetic protein receptor type 2

involved_in

GO_REF:0000024

AgBase

GO_REF:0000024

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

Carm1

coactivator-associated arginine methyltransferase 1

acts_upstream_of_or_within

MGI:2663959 (MGI:4365886|PMID:19725955)

PMID:19725955

MGI:4365886

NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689

Col3a1

collagen type III alpha 1 chain

involved_in

MGI:1860700 (MGI:3796350|PMID:17960558)

PMID:17960558

MGI:3796350

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

Dspp

dentin sialophosphoprotein

acts_upstream_of_or_within

MGI:2653208 (MGI:6187806|PMID:26972716)

PMID:26972716

MGI:6187806

NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

MGI:1857079 (MGI:5661140|PMID:22359666)

PMID:22359666

MGI:5661140

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

exostosin glycosyltransferase 1

acts_upstream_of_or_within

MGI:108050 (MGI:6199721|PMID:29545125), (MGI:6406739|PMID:21310272)

PMID:21310272 PMID:29545125

MGI:6199721 MGI:6406739

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

Ext2

exostosin glycosyltransferase 2

acts_upstream_of_or_within

MGI:894663 (MGI:6406739|PMID:21310272)

PMID:21310272

MGI:6406739

NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059

Ihh

Indian hedgehog signaling molecule

involved_in

(MGI:1344187|PMID:10465785), (MGI:1351296|PMID:10631175)

PMID:10465785 PMID:10631175

MGI:1344187 MGI:1351296

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

SRY-box transcription factor 9

acts_upstream_of_or_within

MGI:2158693 (MGI:2135696|PMID:11371614)

PMID:11371614

MGI:2135696

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

endochondral ossification

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alpl

alkaline phosphatase, biomineralization associated

acts_upstream_of_or_within

MGI:2183411 (MGI:5049900|PMID:20684022)

PMID:20684022

MGI:5049900

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

bone morphogenetic protein 4

involved_in

ISS
ISO
IEA

GO_REF:0000024
(MGI:4418577|PMID:20059955)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:20059955

GO_REF:0000024 GO_REF:0000107 MGI:4418577

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Bmp6

bone morphogenetic protein 6

acts_upstream_of_or_within

MGI:2136985 (MGI:1270957|PMID:9664685)

PMID:9664685

MGI:1270957

NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365

Bpnt2

3'(2'), 5'-bisphosphate nucleotidase 2

acts_upstream_of_or_within

MGI:3806990 (MGI:3799383|PMID:18539921)

PMID:18539921

MGI:3799383

NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570

Cbs

cystathionine beta synthase

acts_upstream_of_or_within

MGI:1857139 (MGI:3656462|PMID:15622513)

PMID:15622513

MGI:3656462

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

Col10a1

collagen type X alpha 1 chain

IMP

RGD

PMID:10853827

RGD:704421

NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494

Col13a1

collagen type XIII alpha 1 chain

involved_in

(MGI:2157681|PMID:11470398)

PMID:11470398

MGI:2157681

NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032

collagen type I alpha 1 chain

acts_upstream_of_or_within

MGI:1856671 (MGI:64698|PMID:8130375)

PMID:8130375

MGI:64698

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

collagen type II alpha 1 chain

acts_upstream_of_or_within

(MGI:1334159|PMID:10100048)

PMID:10100048

MGI:1334159

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Csgalnact1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

acts_upstream_of_or_within

MGI:4947395 (MGI:4946456|PMID:21148564)

PMID:21148564

MGI:4946456

NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319

Cst5

cystatin D

involved_in

MGI:3629665 (MGI:3629269|PMID:16680148)

PMID:16680148

MGI:3629269

NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754

Dlx5

distal-less homeobox 5

involved_in

IEA
ISO
ISS

GO_REF:0000107
(MGI:4413604|PMID:19956613)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:19956613

GO_REF:0000024 GO_REF:0000107 MGI:4413604

NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

MGI:6402836 (MGI:6101307|PMID:24770645)

PMID:24770645

MGI:6101307

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

exostosin glycosyltransferase 1

acts_upstream_of_or_within

(MGI:4946896|PMID:21185280), (MGI:5528913|PMID:23958822)

PMID:21185280 PMID:23958822

MGI:4946896 MGI:5528913

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

Fgf18

fibroblast growth factor 18

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2178751 (MGI:3703411|PMID:17014841)

PMID:17014841

GO_REF:0000107 MGI:3703411

NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818

Foxc1

forkhead box C1

involved_in

(MGI:5641778|PMID:25808752)

PMID:25808752

MGI:5641778

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

Gnas

GNAS complex locus

acts_upstream_of_or_within

MGI:3043361 (MGI:3619837|PMID:15797856)

PMID:15797856

MGI:3619837

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

Hspg2

heparan sulfate proteoglycan 2

acts_upstream_of_or_within

MGI:1934892 (MGI:1349497|PMID:10579729)

PMID:10579729

MGI:1349497

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

intraflagellar transport 80

acts_upstream_of_or_within

MGI:3665440|MGI:5818514 (MGI:5817320|PMID:26098911)

PMID:26098911

MGI:5817320

NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024

Inppl1

inositol polyphosphate phosphatase-like 1

involved_in

IEA
ISO
ISS

GO_REF:0000107
(PMID:23273569)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:23273569

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500

Mef2c

myocyte enhancer factor 2C

acts_upstream_of_or_within

MGI:99533 (MGI:3701381|PMID:17336904)

PMID:17336904

MGI:3701381

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

Mef2d

myocyte enhancer factor 2D

acts_upstream_of_or_within
involved_in

MGI:99458 (MGI:3701381|PMID:17336904)
GO_REF:0000107

PMID:17336904

GO_REF:0000107 MGI:3701381

NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457

Mmp13

matrix metallopeptidase 13

involved_in

IEP
ISO
IEA

(MGI:3771509|PMID:17987127)
GO_REF:0000107

PMID:17987127 PMID:10646117

GO_REF:0000107 MGI:3771509, RGD:10043159

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

Mmp14

matrix metallopeptidase 14

acts_upstream_of_or_within

MGI:1276107 (MGI:3771253|PMID:18022611)

MGI:3771253

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

Mmp16

matrix metallopeptidase 16

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:101900 (MGI:3771253|PMID:18022611)

GO_REF:0000107 MGI:3771253

NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388

Nab1

Ngfi-A binding protein 1

acts_upstream_of_or_within

MGI:107563 (MGI:3583879|PMID:16136673)

PMID:16136673

MGI:3583879

NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098

Nab2

Ngfi-A binding protein 2

acts_upstream_of_or_within

MGI:107564 (MGI:3583879|PMID:16136673)

PMID:16136673

MGI:3583879

NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989

Nfix

nuclear factor I X

involved_in

MGI:3714028 (MGI:3713631|PMID:17353270)

PMID:17353270

MGI:3713631

NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265

Npr2

natriuretic peptide receptor 2

involved_in

PMID:15572448 PMID:15722353 PMID:17728275

MGI:3513731 MGI:3579766 MGI:3770504

NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580

Pex7

peroxisomal biogenesis factor 7

acts_upstream_of_or_within

MGI:3052739 (MGI:3052413|PMID:12915479)

PMID:12915479

MGI:3052413

NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748

Phospho1

phosphoethanolamine/phosphocholine phosphatase 1

acts_upstream_of_or_within

MGI:5049904 (MGI:5049900|PMID:20684022)

PMID:20684022

MGI:5049900

NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342

Pthlh

parathyroid hormone-like hormone

acts_upstream_of_or_within

MGI:2154515 (MGI:1352921|PMID:8895385)

PMID:8895385

MGI:1352921

NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847

Runx2

RUNX family transcription factor 2

acts_upstream_of_or_within
involved_in

MGI:2176466 (MGI:1332911|PMID:10072783)
GO_REF:0000107

PMID:10072783

GO_REF:0000107 MGI:1332911

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

Scx

scleraxis bHLH transcription factor

involved_in

(MGI:4418577|PMID:20059955)

PMID:20059955

MGI:4418577

NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626

Sik3

SIK family kinase 3

acts_upstream_of_or_within

MGI:5317918 (MGI:5316542|PMID:22318228)

PMID:22318228

MGI:5316542

NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444

Smpd3

sphingomyelin phosphodiesterase 3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856877|MGI:3575405 (MGI:3715574|PMID:17591962), (MGI:5293259|PMID:21788370), (MGI:5582670|PMID:24505141)

PMID:17591962 PMID:21788370 PMID:24505141

GO_REF:0000107 MGI:3715574 MGI:5293259 MGI:5582670

NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749

Tek

TEK receptor tyrosine kinase

RGD

PMID:11735002

RGD:1601509

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

Tmem119

transmembrane protein 119

involved_in

(MGI:5543589|PMID:22416756)

PMID:22416756

MGI:5543589

NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689

frontal suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:4821204|PMID:20570969)

PMID:20570969

MGI:4821204

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

Msx2

msh homeobox 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)

PMID:10742104

GO_REF:0000107 MGI:1355063

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

Tgfb1

transforming growth factor, beta 1

RGD

PMID:12416537

RGD:2302805

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

Tgfb2

transforming growth factor, beta 2

RGD

PMID:12416537

RGD:2302805

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tgfb3

transforming growth factor, beta 3

RGD

PMID:12416537

RGD:2302805

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

growth plate cartilage axis specification

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Stc1

stanniocalcin 1

involved_in

(PMID:16377640)

PMID:16377640

NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264

growth plate cartilage chondrocyte development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Col27a1

collagen type XXVII alpha 1 chain

acts_upstream_of_or_within

MGI:5315593 (MGI:5315238|PMID:22206015)

PMID:22206015

MGI:5315238

NCBI chr 5:76,647,302...76,765,987
Ensembl chr 5:76,647,429...76,765,174

Poc1a

POC1 centriolar protein A

acts_upstream_of_or_within

MGI:2135614 (MGI:5700251|PMID:26496357)

PMID:26496357

MGI:5700251

NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089

Tsku

tsukushi, small leucine rich proteoglycan

involved_in

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

growth plate cartilage chondrocyte differentiation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anxa6

annexin A6

involved_in

IBA

PMID:21873635

GO_Central

PMID:21873635

NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433

Atf2

activating transcription factor 2

involved_in

MGI:1857283 (MGI:3807134|PMID:18638549)

PMID:18638549

MGI:3807134

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

intraflagellar transport 80

acts_upstream_of_or_within

MGI:3665440|MGI:5818514 (MGI:5817320|PMID:26098911)

PMID:26098911

MGI:5817320

NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024

Nppc

natriuretic peptide C

involved_in

(MGI:2177134|PMID:11259675)
GO_REF:0000024

PMID:11259675

GO_REF:0000024 MGI:2177134

NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251

growth plate cartilage chondrocyte growth

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cst5

cystatin D

involved_in

MGI:3629665 (MGI:3629269|PMID:16680148)

PMID:16680148

MGI:3629269

NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754

Rarg

retinoic acid receptor, gamma

involved_in

(MGI:3848572|PMID:19389355)

NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177

SRY-box transcription factor 9

involved_in

GO_REF:0000024
(MGI:5317468|PMID:22421045)

PMID:22421045

GO_REF:0000024 MGI:5317468

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

Tgfbr2

transforming growth factor, beta receptor 2

acts_upstream_of_or_within

MGI:2384513 (MGI:4949016|PMID:21420963)

PMID:21420963

MGI:4949016

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

growth plate cartilage chondrocyte morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Matn1

matrilin 1

acts_upstream_of_or_within

MGI:2153042|MGI:3663272 (MGI:3655339|PMID:16877353)

PMID:16877353

MGI:3655339

NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059

growth plate cartilage chondrocyte proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atf2

activating transcription factor 2

involved_in

MGI:1857283 (MGI:3807134|PMID:18638549)

PMID:18638549

MGI:3807134

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

Cer1

cerberus 1, DAN family BMP antagonist

involved_in

(MGI:5315688|PMID:19113921)

PMID:19113921

MGI:5315688

NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783

Nppc

natriuretic peptide C

involved_in

(MGI:2177134|PMID:11259675)
GO_REF:0000024

PMID:11259675

GO_REF:0000024 MGI:2177134

NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251

growth plate cartilage development

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

collagen type II alpha 1 chain

spheno-occipital synchondrosis

RGD

PMID:20591638

RGD:8661256

NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546

Col9a1

collagen type IX alpha 1 chain

acts_upstream_of_or_within

MGI:2152964|MGI:88469|MGI:98737|MGI:98739 (MGI:3795666|PMID:18467703), (MGI:3807836|PMID:18191556)

PMID:18191556 PMID:18467703

MGI:3795666 MGI:3807836

NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213

Comp

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

PMID:17588960 PMID:18191556 PMID:18467703

GO_REF:0000107 MGI:3723532 MGI:3795666 MGI:3807836

NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845

intraflagellar transport 80

acts_upstream_of_or_within

MGI:3665440|MGI:5818514 (MGI:5817320|PMID:26098911)

PMID:26098911

MGI:5817320

NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024

Mmp13

matrix metallopeptidase 13

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:98729 (MGI:4949554|PMID:21444811)

PMID:21444811

GO_REF:0000107 MGI:4949554

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

Npr2

natriuretic peptide receptor 2

involved_in

MGI:3774275|MGI:4358115 (MGI:3770504|PMID:17728275), (MGI:5442436|PMID:23065701)

PMID:17728275 PMID:23065701

MGI:3770504 MGI:5442436

NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580

Rara

retinoic acid receptor, alpha

acts_upstream_of_or_within

MGI:97858 (MGI:3848572|PMID:19389355)

NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142

Rarb

retinoic acid receptor, beta

acts_upstream_of_or_within

MGI:97858 (MGI:3848572|PMID:19389355)

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

Rarg

retinoic acid receptor, gamma

acts_upstream_of_or_within

MGI:97856|MGI:97857 (MGI:3848572|PMID:19389355)

NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177

Tgfbr2

transforming growth factor, beta receptor 2

acts_upstream_of_or_within

MGI:1340026 (MGI:4949016|PMID:21420963)

PMID:21420963

MGI:4949016

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

Thbs1

thrombospondin 1

acts_upstream_of_or_within

MGI:2154534|MGI:88465|MGI:88469|MGI:98739 (MGI:3795666|PMID:18467703)

PMID:18467703

MGI:3795666

NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440

Thbs3

thrombospondin 3

acts_upstream_of_or_within

MGI:3581964|MGI:88465|MGI:88469|MGI:98737 (MGI:3795666|PMID:18467703)

PMID:18467703

MGI:3795666

NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594

Zmpste24

zinc metallopeptidase STE24

acts_upstream_of_or_within

MGI:2180033 (MGI:2178865|PMID:11923874)

PMID:11923874

MGI:2178865

NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110

lambdoid suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:4821204|PMID:20570969)

PMID:20570969

MGI:4821204

NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712

negative regulation of bone trabecula formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Chad

chondroadherin

acts_upstream_of_or_within
involved_in

MGI:5529270 (MGI:5525032|PMID:23755099)
GO_REF:0000107

PMID:23755099

GO_REF:0000107 MGI:5525032

NCBI chr10:79,512,170...79,515,941
Ensembl chr10:79,511,931...79,515,940

Cyp27b1

cytochrome P450, family 27, subfamily b, polypeptide 1

IMP

RGD

PMID:32231239

RGD:32716373

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

Grem1

gremlin 1, DAN family BMP antagonist

involved_in

(PMID:15539560)

PMID:15539560

NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082

vitamin D receptor

RGD

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

negative regulation of growth plate cartilage chondrocyte proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dspp

dentin sialophosphoprotein

acts_upstream_of_or_within

MGI:2653208 (MGI:6187806|PMID:26972716)

PMID:26972716

MGI:6187806

NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672

perichondral bone morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

exostosin glycosyltransferase 1

acts_upstream_of_or_within

(MGI:6407539|PMID:28768899)

PMID:28768899

MGI:6407539

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

regulation of growth plate cartilage chondrocyte proliferation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Carm1

coactivator-associated arginine methyltransferase 1

acts_upstream_of_or_within

MGI:2663959 (MGI:4365886|PMID:19725955)

PMID:19725955

MGI:4365886

NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689

Por

cytochrome p450 oxidoreductase

IMP

positive regulation

RGD

PMID:19264869

RGD:2316785

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

sagittal suture morphogenesis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GLI family zinc finger 3

acts_upstream_of_or_within

MGI:1856276 (MGI:4821204|PMID:20570969)