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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of axon regeneration
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Accession:GO:0048679 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of axon regeneration.


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regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO MGI:MGI:2443718 (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO MGI:MGI:1346866|MGI:MGI:1346867 (MGI:MGI:5582953|PMID:24733831) RGD PMID:24733831 MGI:MGI:5582953 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Klf4 Kruppel like factor 4 ISO MGI:MGI:103038 (MGI:MGI:5547847|PMID:24129709) RGD PMID:24129709 MGI:MGI:5547847 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 ISO MGI:MGI:1096335|MGI:MGI:1097159 (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 2:206,928,708...206,997,915
Ensembl chr 2:206,931,204...206,997,519
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO MGI:MGI:1346867|MGI:MGI:88190 (MGI:MGI:5582953|PMID:24733831) RGD PMID:24733831 MGI:MGI:5582953 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO MGI:MGI:1346866|MGI:MGI:88190 (MGI:MGI:5582953|PMID:24733831) RGD PMID:24733831 MGI:MGI:5582953 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Neo1 neogenin 1 ISO MGI:MGI:2443718 (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Pten phosphatase and tensin homolog ISO MGI:MGI:88190 (MGI:MGI:5582953|PMID:24733831) RGD PMID:24733831 MGI:MGI:5582953 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F ISO
IEA
(MGI:MGI:5294249|PMID:21976490)
GO_REF:0000107
RGD
Ensembl
PMID:21976490 GO_REF:0000107, MGI:MGI:5294249 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927
JBrowse link
G Stk24 serine/threonine kinase 24 IEA
ISO
GO_REF:0000107
(PMID:19855390)
Ensembl
RGD
PMID:19855390 GO_REF:0000107 NCBI chr15:106,629,258...106,678,917
Ensembl chr15:106,629,312...106,678,918
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGD1307443 similar to mKIAA0319 protein ISO MGI:MGI:4362922 (MGI:MGI:5904726|PMID:28334068)
(PMID:28334068)
RGD PMID:28334068 MGI:MGI:5904726 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Tnr tenascin R ISO
IEA
MGI:MGI:2154583 (MGI:MGI:3652670|PMID:16870730)
GO_REF:0000107
RGD
Ensembl
PMID:16870730 GO_REF:0000107, MGI:MGI:3652670 NCBI chr13:77,602,249...77,678,385
Ensembl chr13:77,485,113...77,678,437
JBrowse link
negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers2 ceramide synthase 2 IMP PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Epha4 Eph receptor A4 NOT IMP
ISS
ISO
GO_REF:0000024
(MGI:MGI:3530975|PMID:15537875)
UniProt
RGD
PMID:15537875, PMID:17970742, PMID:17418490 GO_REF:0000024, MGI:MGI:3530975, RGD:5688750, RGD:5688782 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F ISO (MGI:MGI:5694525|PMID:26203138) RGD PMID:26203138 MGI:MGI:5694525 NCBI chr 1:200,037,749...200,116,524
Ensembl chr 1:200,037,749...200,116,524
JBrowse link
G Klk8 kallikrein related-peptidase 8 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3766680|PMID:17629414)
Ensembl
UniProt
RGD
PMID:17629414 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3766680 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:6274963|PMID:24167472)
Ensembl
RGD
PMID:24167472 GO_REF:0000107, MGI:MGI:6274963 NCBI chr14:85,441,209...85,503,661
Ensembl chr14:85,438,707...85,484,275
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 ISO (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 2:206,928,708...206,997,915
Ensembl chr 2:206,931,204...206,997,519
JBrowse link
G Neo1 neogenin 1 ISO (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 8:63,649,871...63,756,394
Ensembl chr 8:63,653,266...63,750,531
JBrowse link
G Pten phosphatase and tensin homolog ISO (MGI:MGI:5694525|PMID:26203138) RGD PMID:26203138 MGI:MGI:5694525 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:4880863|PMID:19780196), (MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19780196, PMID:22406547 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4880863, MGI:MGI:5461303 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IMP RGD PMID:16585268 RGD:9850138 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
RGD
UniProt
PMID:22406547 GO_REF:0000024, MGI:MGI:5461303 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 ISO
ISS
(MGI:MGI:5461303|PMID:22406547)
GO_REF:0000024
RGD
UniProt
PMID:22406547 GO_REF:0000024, MGI:MGI:5461303 NCBI chr10:62,035,866...62,109,075
Ensembl chr10:62,035,866...62,109,078
JBrowse link
G Xylt1 xylosyltransferase 1 IMP RGD PMID:18765417 RGD:2313145 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spp1 secreted phosphoprotein 1 IEP RGD PMID:15625076 RGD:1581125 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
negative regulation of formation of growth cone in injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtn4 reticulon 4 ISO MGI:MGI:3623522 (MGI:MGI:3621687|PMID:12718855) RGD PMID:12718855 MGI:MGI:3621687 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
positive regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor IDA PMID:16699509 CAFA PMID:16699509 RGD:12793002 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Lrp1 LDL receptor related protein 1 IDA RGD PMID:23867460 RGD:13800520 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO MGI:MGI:97380 (MGI:MGI:3604840|PMID:16142215) RGD PMID:16142215 MGI:MGI:3604840 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Ocm oncomodulin IDA PMID:16699509 CAFA PMID:16699509 RGD:12793002 NCBI chr12:12,611,121...12,634,472
Ensembl chr12:12,624,723...12,634,472
JBrowse link
positive regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO (MGI:MGI:5582953|PMID:24733831) RGD PMID:24733831 MGI:MGI:5582953 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Cntf ciliary neurotrophic factor IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:15574731, PMID:21873635 RGD:1626128, RGD:13792537 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IDA RGD PMID:9512405 RGD:7205517 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Flna filamin A ISO (MGI:MGI:6378072|PMID:26157139) RGD PMID:26157139 MGI:MGI:6378072 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Grn granulin precursor ISS
ISO
GO_REF:0000024
(MGI:MGI:5907533|PMID:28453791)
UniProt
RGD
PMID:28453791 GO_REF:0000024, MGI:MGI:5907533 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:23349896 RGD:10046026 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Mif macrophage migration inhibitory factor IMP RGD PMID:12456989 RGD:1642004 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 IMP RGD PMID:18431495 RGD:2306515 NCBI chr10:55,398,919...55,456,654
Ensembl chr10:55,411,901...55,444,861
JBrowse link
G Nrg1 neuregulin 1 IDA RGD PMID:20957456 RGD:10449012 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Ptn pleiotrophin IDA PMID:27671118 UniProt PMID:27671118 RGD:14397577 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Scarf1 scavenger receptor class F, member 1 ISO (MGI:MGI:3772611|PMID:18160648) RGD PMID:18160648 MGI:MGI:3772611 NCBI chr10:63,662,967...63,683,916
Ensembl chr10:63,662,986...63,670,639
JBrowse link
G Stk24 serine/threonine kinase 24 IMP RGD PMID:19855390 RGD:2317003 NCBI chr15:106,629,258...106,678,917
Ensembl chr15:106,629,312...106,678,918
JBrowse link
positive regulation of collateral sprouting of injured axon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp1 LDL receptor related protein 1 IDA RGD PMID:23867460 RGD:13800520 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Rtn4 reticulon 4 ISO MGI:MGI:3623522 (MGI:MGI:3621687|PMID:12718855) RGD PMID:12718855 MGI:MGI:3621687 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
positive regulation of optical nerve axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ocm oncomodulin IDA PMID:16699509 CAFA PMID:16699509 RGD:12793002 NCBI chr12:12,611,121...12,634,472
Ensembl chr12:12,624,723...12,634,472
JBrowse link
regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Omg oligodendrocyte-myelin glycoprotein ISO MGI:MGI:3821628 (MGI:MGI:3820448|PMID:18692574) RGD PMID:18692574 MGI:MGI:3820448 NCBI chr10:66,845,654...66,848,388
Ensembl chr10:66,845,654...66,848,388
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20022
    regulation of biological process 13069
      regulation of response to stimulus 3995
        regulation of response to external stimulus 976
          regulation of axon regeneration 38
            negative regulation of axon regeneration + 17
            positive regulation of axon regeneration + 16
            regulation of collateral sprouting of intact axon in response to injury + 2
            regulation of optical nerve axon regeneration + 1
Path 2
Term Annotations click to browse term
  biological_process 20022
    developmental process 6817
      anatomical structure development 6263
        multicellular organism development 5741
          system development 5276
            nervous system development 2721
              neurogenesis 1937
                generation of neurons 1780
                  neuron differentiation 1616
                    neuron development 1322
                      neuron projection development 1162
                        neuron projection regeneration 83
                          axon regeneration 72
                            regulation of axon regeneration 38
                              negative regulation of axon regeneration + 17
                              positive regulation of axon regeneration + 16
                              regulation of collateral sprouting of intact axon in response to injury + 2
                              regulation of optical nerve axon regeneration + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.