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ONTOLOGY REPORT - ANNOTATIONS


Term:neuron fate commitment
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Accession:GO:0048663 term browser browse the term
Definition:The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
Synonyms:exact_synonym: neuron lineage restriction;   neuronal lineage restriction
 alt_id: GO:0042055


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neuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:5897542|PMID:24243019)
(MGI:2651973|PMID:12629181), (MGI:3639800|PMID:16715081), (MGI:4353883|PMID:19191219)
(MGI:3587461|PMID:16020526)
UniProt
MGI
PMID:12629181, PMID:16020526, PMID:16715081, PMID:19191219, PMID:24243019 MGI:2651973, MGI:3587461, MGI:3639800, MGI:4353883, MGI:5897542 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO (MGI:3761972|PMID:17698011) MGI PMID:17698011 MGI:3761972 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Foxn4 forkhead box N4 ISO (MGI:3587461|PMID:16020526) MGI PMID:16020526 MGI:3587461 NCBI chrNW_004955455:9,182,405...9,210,365
Ensembl chrNW_004955455:9,183,475...9,210,506
JBrowse link
G Gata2 GATA binding protein 2 ISO (MGI:3827070|PMID:19088086) MGI PMID:19088086 MGI:3827070 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460
JBrowse link
G Gbx1 gastrulation brain homeobox 1 ISO (MGI:5511092|PMID:24010020) MGI PMID:24010020 MGI:5511092 NCBI chrNW_004955491:5,575,836...5,592,804 JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3610448|PMID:16168404) MGI PMID:16168404 MGI:3610448 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Gsx1 GS homeobox 1 ISO (MGI:3639800|PMID:16715081) MGI PMID:16715081 MGI:3639800 NCBI chrNW_004955497:7,167,915...7,169,177
Ensembl chrNW_004955497:7,167,915...7,169,177
JBrowse link
G Gsx2 GS homeobox 2 ISO (MGI:3639800|PMID:16715081) MGI PMID:16715081 MGI:3639800 NCBI chrNW_004955447:16,714,870...16,715,757 JBrowse link
G Id2 inhibitor of DNA binding 2 ISO (MGI:4821067|PMID:17681138) UniProt PMID:17681138 MGI:4821067 NCBI chrNW_004955487:878,326...880,783
Ensembl chrNW_004955487:878,326...880,783
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:3041365|PMID:14766174) MGI PMID:14766174 MGI:3041365 NCBI chrNW_004955446:15,824,956...15,835,000
Ensembl chrNW_004955446:15,824,035...15,835,046
JBrowse link
G Isl2 ISL LIM homeobox 2 ISO (MGI:3041365|PMID:14766174) MGI PMID:14766174 MGI:3041365 NCBI chrNW_004955450:1,471,586...1,475,702
Ensembl chrNW_004955450:1,470,864...1,475,965
JBrowse link
G Lbx1 ladybird homeobox 1 ISO (MGI:2179904|PMID:12062039) MGI PMID:12062039 MGI:2179904 NCBI chrNW_004955485:9,003,329...9,005,987
Ensembl chrNW_004955485:9,003,329...9,005,989
JBrowse link
G Myt1l myelin transcription factor 1 like ISO (MGI:5897487|PMID:28379941), (MGI:5897542|PMID:24243019) UniProt PMID:24243019, PMID:28379941 MGI:5897487, MGI:5897542 NCBI chrNW_004955487:4,457,145...4,855,369
Ensembl chrNW_004955487:4,725,889...4,855,369
JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO (MGI:3834782|PMID:18786356), (MGI:4437145|PMID:20181579) MGI PMID:18786356, PMID:20181579 MGI:3834782, MGI:4437145 NCBI chrNW_004955409:24,612,490...24,616,360
Ensembl chrNW_004955409:24,612,635...24,616,430
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:3604921|PMID:16120638) MGI PMID:16120638 MGI:3604921 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Notch3 notch receptor 3 ISO (MGI:3604921|PMID:16120638) MGI PMID:16120638 MGI:3604921 NCBI chrNW_004955495:8,012,370...8,048,616
Ensembl chrNW_004955495:8,012,502...8,047,710
JBrowse link
G Nrg1 neuregulin 1 ISO (MGI:2136155|PMID:11425901) MGI PMID:11425901 MGI:2136155 NCBI chrNW_004955463:8,009,436...9,037,116
Ensembl chrNW_004955463:8,009,530...9,037,116
JBrowse link
G Olig1 oligodendrocyte transcription factor 1 ISO (MGI:2177979|PMID:11955448) MGI PMID:11955448 MGI:2177979 NCBI chrNW_004955407:32,471,501...32,480,358
Ensembl chrNW_004955407:32,471,516...32,479,079
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 ISO (MGI:2177979|PMID:11955448) MGI PMID:11955448 MGI:2177979 NCBI chrNW_004955407:32,432,888...32,436,209
Ensembl chrNW_004955407:32,433,849...32,434,923
JBrowse link
G Otx2 orthodenticle homeobox 2 ISO (MGI:3611719|PMID:16339193)
(MGI:5689191|PMID:26166575)
MGI PMID:16339193, PMID:26166575 MGI:3611719, MGI:5689191 NCBI chrNW_004955466:10,755,143...10,764,957
Ensembl chrNW_004955466:10,755,012...10,765,095
JBrowse link
G Pax3 paired box 3 ISO (MGI:1321412|PMID:9858722) MGI PMID:9858722 MGI:1321412 NCBI chrNW_004955453:11,463,407...11,558,001
Ensembl chrNW_004955453:11,463,379...11,558,006
JBrowse link
G Pax7 paired box 7 ISO (MGI:1321412|PMID:9858722) MGI PMID:9858722 MGI:1321412 NCBI chrNW_004955527:474,450...573,869
Ensembl chrNW_004955527:474,403...574,689
JBrowse link
G Pou3f2 POU class 3 homeobox 2 ISO (MGI:5897542|PMID:24243019) UniProt PMID:24243019 MGI:5897542 NCBI chrNW_004955411:24,714,899...24,722,048
Ensembl chrNW_004955411:24,715,088...24,716,695
JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO (MGI:3590363|PMID:16039563) MGI PMID:16039563 MGI:3590363 NCBI chrNW_004955429:5,807,804...5,809,522
Ensembl chrNW_004955429:5,808,124...5,809,522
JBrowse link
G Shh sonic hedgehog signaling molecule ISO (MGI:3608263|PMID:16221724) MGI PMID:16221724 MGI:3608263 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Smad4 SMAD family member 4 ISO (MGI:3761972|PMID:17698011) MGI PMID:17698011 MGI:3761972 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538
JBrowse link
G Sox2 SRY-box transcription factor 2 ISO (MGI:3664123|PMID:17015430) MGI PMID:17015430 MGI:3664123 NCBI chrNW_004955420:10,671,888...10,674,080
Ensembl chrNW_004955420:10,671,978...10,672,934
JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (MGI:3588127|PMID:15744664) MGI PMID:15744664 MGI:3588127 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248
JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (MGI:3588127|PMID:15744664) MGI PMID:15744664 MGI:3588127 NCBI chrNW_004955419:26,490,899...26,546,349
Ensembl chrNW_004955419:26,490,899...26,547,017
JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:3611719|PMID:16339193) MGI PMID:16339193 MGI:3611719 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167
JBrowse link
G Znf521 zinc finger protein 521 ISO (MGI:5641108|PMID:25834056) MGI PMID:25834056 MGI:5641108 NCBI chrNW_004955402:13,299,670...13,570,188
Ensembl chrNW_004955402:13,299,432...13,571,898
JBrowse link
auditory receptor cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag2 jagged canonical Notch ligand 2 ISO (MGI:1332721|PMID:10080181) UniProt PMID:10080181 MGI:1332721 NCBI chrNW_004955538:3,421,685...3,433,829
Ensembl chrNW_004955538:3,421,685...3,433,842
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:3833041|PMID:19154718) MGI PMID:19154718 MGI:3833041 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:3833041|PMID:19154718) MGI PMID:19154718 MGI:3833041 NCBI chrNW_004955443:18,783,061...19,029,441
Ensembl chrNW_004955443:18,783,061...18,910,228
JBrowse link
auditory receptor cell fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 ISO (MGI:3611666|PMID:16407553) MGI PMID:16407553 MGI:3611666 NCBI chrNW_004955405:4,461,704...4,462,756
Ensembl chrNW_004955405:4,461,704...4,462,756
JBrowse link
auditory receptor cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh1 atonal bHLH transcription factor 1 ISO (MGI:1339217|PMID:10364557) MGI PMID:10364557 MGI:1339217 NCBI chrNW_004955405:4,461,704...4,462,756
Ensembl chrNW_004955405:4,461,704...4,462,756
JBrowse link
camera-type eye photoreceptor cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ihh Indian hedgehog signaling molecule ISO (MGI:3807419|PMID:18582859) MGI PMID:18582859 MGI:3807419 NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747
JBrowse link
cerebral cortex GABAergic interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlx1 distal-less homeobox 1 ISO (MGI:3775335|PMID:17678855) MGI PMID:17678855 MGI:3775335 NCBI chrNW_004955449:2,920,705...2,924,667
Ensembl chrNW_004955449:2,920,478...2,924,667
JBrowse link
G Dlx2 distal-less homeobox 2 ISO (MGI:3775335|PMID:17678855) MGI PMID:17678855 MGI:3775335 NCBI chrNW_004955449:2,907,502...2,909,893
Ensembl chrNW_004955449:2,907,436...2,910,816
JBrowse link
commitment of neuronal cell to specific neuron type in forebrain term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:5439194|PMID:22991444) MGI PMID:22991444 MGI:5439194 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B ISO (MGI:5464968|PMID:23144223) MGI PMID:23144223 MGI:5464968 NCBI chrNW_004955438:20,562,345...20,637,662
Ensembl chrNW_004955438:20,564,449...20,637,103
JBrowse link
G Fezf2 FEZ family zinc finger 2 ISO (MGI:5464968|PMID:23144223)
(MGI:5140686|PMID:21338885)
MGI PMID:21338885, PMID:23144223 MGI:5140686, MGI:5464968 NCBI chrNW_004955517:3,439,999...3,443,477
Ensembl chrNW_004955517:3,439,999...3,443,846
JBrowse link
G Gata2 GATA binding protein 2 ISO (MGI:5439194|PMID:22991444) MGI PMID:22991444 MGI:5439194 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460
JBrowse link
G Pax6 paired box 6 ISO (MGI:1928687|PMID:11124115) MGI PMID:11124115 MGI:1928687 NCBI chrNW_004955476:10,058,979...10,074,668
Ensembl chrNW_004955476:10,058,961...10,074,162
JBrowse link
G Satb2 SATB homeobox 2 ISO (MGI:5464968|PMID:23144223) MGI PMID:23144223 MGI:5464968 NCBI chrNW_004955403:1,663,676...1,811,088
Ensembl chrNW_004955403:1,663,676...1,811,109
JBrowse link
G Tbr1 T-box brain transcription factor 1 ISO (MGI:5464968|PMID:23144223) MGI PMID:23144223 MGI:5464968 NCBI chrNW_004955449:12,293,534...12,301,440
Ensembl chrNW_004955449:12,293,601...12,301,272
JBrowse link
eye photoreceptor cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otx2 orthodenticle homeobox 2 ISO (MGI:2680889|PMID:14625556) MGI PMID:14625556 MGI:2680889 NCBI chrNW_004955466:10,755,143...10,764,957
Ensembl chrNW_004955466:10,755,012...10,765,095
JBrowse link
forebrain neuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx6 LIM homeobox 6 ISO (MGI:3794908|PMID:18339674) MGI PMID:18339674 MGI:3794908 NCBI chrNW_004955419:5,835,230...5,858,096
Ensembl chrNW_004955419:5,834,547...5,858,113
JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO (MGI:3794908|PMID:18339674) MGI PMID:18339674 MGI:3794908 NCBI chrNW_004955409:24,612,490...24,616,360
Ensembl chrNW_004955409:24,612,635...24,616,430
JBrowse link
G Tfap2c transcription factor AP-2 gamma ISO (MGI:4397655|PMID:19749747) MGI PMID:19749747 MGI:4397655 NCBI chrNW_004955445:2,626,896...2,636,607
Ensembl chrNW_004955445:2,626,823...2,636,607
JBrowse link
negative regulation of retinal cone cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 ISO (MGI:5629913|PMID:25654255) MGI PMID:25654255 MGI:5629913 NCBI chrNW_004955486:2,923,239...2,975,835 JBrowse link
neuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 ISO (MGI:3664674|PMID:16892058) MGI PMID:16892058 MGI:3664674 NCBI chrNW_004955452:2,255,940...2,299,042
Ensembl chrNW_004955452:2,255,117...2,299,042
JBrowse link
G Fezf2 FEZ family zinc finger 2 ISO (MGI:5604297|PMID:24997765) MGI PMID:24997765 MGI:5604297 NCBI chrNW_004955517:3,439,999...3,443,477
Ensembl chrNW_004955517:3,439,999...3,443,846
JBrowse link
G Foxg1 forkhead box G1 ISO (MGI:5440366|PMID:22726835) MGI PMID:22726835 MGI:5440366 NCBI chrNW_004955409:31,672,960...31,674,970 JBrowse link
G Lbx1 ladybird homeobox 1 ISO (MGI:3607682|PMID:16234809) MGI PMID:16234809 MGI:3607682 NCBI chrNW_004955485:9,003,329...9,005,987
Ensembl chrNW_004955485:9,003,329...9,005,989
JBrowse link
G Otx2 orthodenticle homeobox 2 ISO (MGI:4360136|PMID:19592574) MGI PMID:19592574 MGI:4360136 NCBI chrNW_004955466:10,755,143...10,764,957
Ensembl chrNW_004955466:10,755,012...10,765,095
JBrowse link
G Prrx1 paired related homeobox 1 ISO (MGI:5486509|PMID:23447615) MGI PMID:23447615 MGI:5486509 NCBI chrNW_004955462:6,919,905...6,991,733
Ensembl chrNW_004955462:6,919,899...6,991,733
JBrowse link
G Wnt1 Wnt family member 1 ISO (MGI:3611719|PMID:16339193) MGI PMID:16339193 MGI:3611719 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167
JBrowse link
neuron fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:5897542|PMID:24243019)
(MGI:3639051|PMID:16469766)
UniProt
MGI
PMID:16469766, PMID:24243019 MGI:3639051, MGI:5897542 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:3823133|PMID:18997111) UniProt PMID:18997111 MGI:3823133 NCBI chrNW_004955411:3,478,943...3,486,541
Ensembl chrNW_004955411:3,478,033...3,486,604
JBrowse link
G Dmrta2 DMRT like family A2 ISO (MGI:5013657|PMID:21576465) MGI PMID:21576465 MGI:5013657 NCBI chrNW_004955464:8,493,392...8,498,007
Ensembl chrNW_004955464:8,495,055...8,497,909
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO (MGI:5577209|PMID:24584053) MGI PMID:24584053 MGI:5577209 NCBI chrNW_004955437:396,736...411,144
Ensembl chrNW_004955437:396,742...411,144
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO (MGI:5319720|PMID:22513373) MGI PMID:22513373 MGI:5319720 NCBI chrNW_004955444:8,336,071...8,655,041
Ensembl chrNW_004955444:8,495,530...8,655,100
JBrowse link
G Fev FEV transcription factor, ETS family member ISO (MGI:4836772|PMID:20818386) MGI PMID:20818386 MGI:4836772 NCBI chrNW_004955453:14,449,352...14,453,145
Ensembl chrNW_004955453:14,449,352...14,452,663
JBrowse link
G Foxa1 forkhead box A1 ISO (MGI:3720545|PMID:17596284) MGI PMID:17596284 MGI:3720545 NCBI chrNW_004955409:23,598,127...23,599,827
Ensembl chrNW_004955409:23,598,127...23,599,461
JBrowse link
G Foxa2 forkhead box A2 ISO (MGI:3720545|PMID:17596284)
(MGI:3767119|PMID:17922007)
MGI PMID:17596284, PMID:17922007 MGI:3720545, MGI:3767119 NCBI chrNW_004955415:29,982,940...29,987,093
Ensembl chrNW_004955415:29,982,940...29,986,255
JBrowse link
G Gsx2 GS homeobox 2 ISO (MGI:3579956|PMID:15930101) MGI PMID:15930101 MGI:3579956 NCBI chrNW_004955447:16,714,870...16,715,757 JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:3815381|PMID:18849985) BHF-UCL PMID:18849985 MGI:3815381 NCBI chrNW_004955446:15,824,956...15,835,000
Ensembl chrNW_004955446:15,824,035...15,835,046
JBrowse link
G Myt1l myelin transcription factor 1 like ISO (MGI:5897487|PMID:28379941), (MGI:5897542|PMID:24243019) UniProt PMID:24243019, PMID:28379941 MGI:5897487, MGI:5897542 NCBI chrNW_004955487:4,457,145...4,855,369
Ensembl chrNW_004955487:4,725,889...4,855,369
JBrowse link
G Nkx2-2 NK2 homeobox 2 ISO (MGI:4360136|PMID:19592574)
(MGI:3611719|PMID:16339193)
MGI PMID:16339193, PMID:19592574 MGI:3611719, MGI:4360136 NCBI chrNW_004955415:29,263,741...29,268,259
Ensembl chrNW_004955415:29,258,434...29,268,259
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO RGD PMID:15247919 RGD:2325628 NCBI chrNW_004955416:16,652,931...17,018,188
Ensembl chrNW_004955416:16,652,791...17,018,188
JBrowse link
G Pou3f2 POU class 3 homeobox 2 ISO (MGI:5897542|PMID:24243019) UniProt PMID:24243019 MGI:5897542 NCBI chrNW_004955411:24,714,899...24,722,048
Ensembl chrNW_004955411:24,715,088...24,716,695
JBrowse link
G Pou4f1 POU class 4 homeobox 1 ISO (MGI:4367920|PMID:19877281), (MGI:4454975|PMID:20096094) BHF-UCL PMID:19877281, PMID:20096094 MGI:4367920, MGI:4454975 NCBI chrNW_004955404:28,812,762...28,818,024 JBrowse link
G Six1 SIX homeobox 1 ISO (MGI:5319720|PMID:22513373) MGI PMID:22513373 MGI:5319720 NCBI chrNW_004955466:8,961,597...8,966,069
Ensembl chrNW_004955466:8,961,597...8,966,069
JBrowse link
G Tlx3 T cell leukemia homeobox 3 ISO (MGI:3607682|PMID:16234809) MGI PMID:16234809 MGI:3607682 NCBI chrNW_004955408:24,103,123...24,105,292
Ensembl chrNW_004955408:24,102,996...24,105,292
JBrowse link
noradrenergic neuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (PMID:14532329) UniProtKB PMID:14532329 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrp1 epithelial splicing regulatory protein 1 ISO (MGI:5915403|PMID:29107558) UniProt PMID:29107558 MGI:5915403 NCBI chrNW_004955417:10,813,831...10,881,238
Ensembl chrNW_004955417:10,813,593...10,882,921
JBrowse link
retinal rod cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casz1 castor zinc finger 1 ISO (MGI:5629913|PMID:25654255) MGI PMID:25654255 MGI:5629913 NCBI chrNW_004955486:2,923,239...2,975,835 JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499
JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955459:8,892,917...9,124,672
Ensembl chrNW_004955459:8,892,869...9,118,499
JBrowse link
G Gli3 GLI family zinc finger 3 ISO (MGI:3051712|PMID:15215207) MGI PMID:15215207 MGI:3051712 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:4355593|PMID:19684112) MGI PMID:19684112 MGI:4355593 NCBI chrNW_004955485:7,805,244...7,925,414
Ensembl chrNW_004955485:7,808,131...7,925,677
JBrowse link
spinal cord motor neuron cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxc10 homeobox C10 ISO (MGI:3771768|PMID:18065432) MGI PMID:18065432 MGI:3771768 NCBI chrNW_004955458:1,243,529...1,248,653
Ensembl chrNW_004955458:1,243,529...1,248,661
JBrowse link
G Hoxd10 homeobox D10 ISO (MGI:3771768|PMID:18065432) MGI PMID:18065432 MGI:3771768 NCBI chrNW_004955403:20,543,224...20,548,801
Ensembl chrNW_004955403:20,543,224...20,548,801
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chrNW_004955446:15,824,956...15,835,000
Ensembl chrNW_004955446:15,824,035...15,835,046
JBrowse link
G Isl2 ISL LIM homeobox 2 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chrNW_004955450:1,471,586...1,475,702
Ensembl chrNW_004955450:1,470,864...1,475,965
JBrowse link
G Lhx3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chrNW_004955513:4,464,149...4,470,962
Ensembl chrNW_004955513:4,464,149...4,470,962
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 ISO (MGI:1344237|PMID:10482234) MGI PMID:10482234 MGI:1344237 NCBI chrNW_004955579:51,862...74,985 JBrowse link
G Olig3 oligodendrocyte transcription factor 3 ISO (MGI:3531376|PMID:15769945) MGI PMID:15769945 MGI:3531376 NCBI chrNW_004955436:21,929,086...21,929,904
Ensembl chrNW_004955436:21,929,086...21,929,904
JBrowse link
subpallium neuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:1321050|PMID:9876181) MGI PMID:9876181 MGI:1321050 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Gsx2 GS homeobox 2 ISO (MGI:1928687|PMID:11124115) MGI PMID:11124115 MGI:1928687 NCBI chrNW_004955447:16,714,870...16,715,757 JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO (MGI:3587461|PMID:16020526) UniProt PMID:16020526 MGI:3587461 NCBI chrNW_004955405:37,941,243...37,943,641
Ensembl chrNW_004955405:37,941,243...37,943,641
JBrowse link
G Dll4 delta like canonical Notch ligand 4 ISO (PMID:17728344) UniProtKB PMID:17728344 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420
JBrowse link
G Foxn4 forkhead box N4 ISO (MGI:3587461|PMID:16020526), (MGI:3765356|PMID:17728344) UniProt PMID:16020526, PMID:17728344 MGI:3587461, MGI:3765356 NCBI chrNW_004955455:9,182,405...9,210,365
Ensembl chrNW_004955455:9,183,475...9,210,506
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 ISO (MGI:1334824|PMID:10217145) MGI PMID:10217145 MGI:1334824 NCBI chrNW_004955415:29,263,741...29,268,259
Ensembl chrNW_004955415:29,258,434...29,268,259
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 ISO (MGI:2136554|PMID:11239429) MGI PMID:11239429 MGI:2136554 NCBI chrNW_004955476:1,018,715...1,022,648
Ensembl chrNW_004955476:1,018,715...1,022,545
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 ISO (MGI:5435948|PMID:22932389) MGI PMID:22932389 MGI:5435948 NCBI chrNW_004955434:5,455,449...5,470,343
Ensembl chrNW_004955434:5,455,449...5,470,343
JBrowse link
G Lhx3 LIM homeobox 3 ISO (MGI:4356383|PMID:19666821) MGI PMID:19666821 MGI:4356383 NCBI chrNW_004955513:4,464,149...4,470,962
Ensembl chrNW_004955513:4,464,149...4,470,962
JBrowse link
G Shh sonic hedgehog signaling molecule ISO PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    cellular process 11098
      cellular developmental process 3640
        cell fate commitment 240
          neuron fate commitment 71
            cardiac neuron fate commitment 0
            cerebral cortex GABAergic interneuron fate commitment 2
            forebrain neuron fate commitment + 10
            inner ear receptor cell fate commitment + 5
            neuron fate determination + 9
            neuron fate specification + 31
            noradrenergic neuron fate commitment + 1
            olfactory bulb interneuron fate commitment 0
            photoreceptor cell fate commitment + 3
            somatic motor neuron fate commitment + 0
            subpallium neuron fate commitment 2
            ventral spinal cord interneuron fate commitment + 11
Path 2
Term Annotations click to browse term
  biological_process 11892
    developmental process 5616
      anatomical structure development 5254
        multicellular organism development 4812
          system development 4532
            nervous system development 2347
              neurogenesis 1687
                generation of neurons 1551
                  neuron differentiation 1403
                    neuron fate commitment 71
                      cardiac neuron fate commitment 0
                      cerebral cortex GABAergic interneuron fate commitment 2
                      forebrain neuron fate commitment + 10
                      inner ear receptor cell fate commitment + 5
                      neuron fate determination + 9
                      neuron fate specification + 31
                      noradrenergic neuron fate commitment + 1
                      olfactory bulb interneuron fate commitment 0
                      photoreceptor cell fate commitment + 3
                      somatic motor neuron fate commitment + 0
                      subpallium neuron fate commitment 2
                      ventral spinal cord interneuron fate commitment + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.