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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of smooth muscle cell proliferation
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Accession:GO:0048661 term browser browse the term
Definition:Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
Synonyms:exact_synonym: positive regulation of SMC proliferation;   up regulation of smooth muscle cell proliferation;   upregulation of smooth muscle cell proliferation
 narrow_synonym: activation of smooth muscle cell proliferation;   stimulation of smooth muscle cell proliferation


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positive regulation of smooth muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link NW_004936472 14,396,986 14,624,597 RGD:9068941
G Ager advanced glycosylation end-product specific receptor JBrowse link NW_004936727 1,418,342 1,422,005 RGD:9068941
G Aif1 allograft inflammatory factor 1 JBrowse link NW_004936727 1,907,493 1,909,350 RGD:9068941
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link NW_004936579 1,312,175 1,328,397 RGD:9068941
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004936621 620,163 639,115 RGD:9068941
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004936697 1,054,237 1,061,468 RGD:9068941
G C3ar1 complement C3a receptor 1 JBrowse link NW_004936892 347,547 355,143 RGD:9068941
G Calcrl calcitonin receptor like receptor JBrowse link NW_004936506 10,191,789 10,292,355 RGD:9068941
G Ccl5 C-C motif chemokine ligand 5 JBrowse link NW_004936490 253,279 259,947 RGD:9068941
G Ccn4 cellular communication network factor 4 JBrowse link NW_004936470 16,110,492 16,134,065 RGD:9068941
G Cdh13 cadherin 13 JBrowse link NW_004936641 3,925,185 4,223,421 RGD:9068941
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link NW_004936475 9,443,851 9,454,715 RGD:9068941
G Edn1 endothelin 1 JBrowse link NW_004936534 885,489 892,292 RGD:9068941
G Egfr epidermal growth factor receptor JBrowse link NW_004936678 365,005 560,546 RGD:9068941
G Egr1 early growth response 1 JBrowse link NW_004936531 7,625,956 7,629,041 RGD:9068941
G Ereg epiregulin JBrowse link NW_004936598 1,328,803 1,336,141 RGD:9068941
G Fgf2 fibroblast growth factor 2 JBrowse link NW_004936662 1,886,176 1,928,998 RGD:9068941
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link NW_004936486 10,506,680 10,606,272 RGD:9068941
G Flt1 fms related receptor tyrosine kinase 1 JBrowse link NW_004936472 23,442,946 23,617,523 RGD:9068941
G Foxp1 forkhead box P1 JBrowse link NW_004936603 2,631,781 3,146,104 RGD:9068941
G Gnaq G protein subunit alpha q JBrowse link NW_004936503 13,098,517 13,276,106 RGD:9068941
G Gsk3b glycogen synthase kinase 3 beta JBrowse link NW_004936536 6,730,070 6,893,818 RGD:9068941
G Hbegf heparin binding EGF like growth factor JBrowse link NW_004936531 9,332,939 9,345,039 RGD:9068941
G Hdac4 histone deacetylase 4 JBrowse link NW_004936745 1,730,743 1,942,071 RGD:9068941
G Hes5 hes family bHLH transcription factor 5 JBrowse link NW_004936737 1,045,496 1,047,865 RGD:9068941
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link NW_004936495 5,770,988 5,816,157 RGD:9068941
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link NW_004936549 1,378,536 1,400,501 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004936492 5,042,353 5,049,216 RGD:9068941
G Id2 inhibitor of DNA binding 2 JBrowse link NW_004936532 5,236,175 5,238,689 RGD:9068941
G Igf1 insulin like growth factor 1 JBrowse link NW_004936492 11,709,623 11,784,028 RGD:9068941
G Igf1r insulin like growth factor 1 receptor JBrowse link NW_004936483 4,563,995 4,860,231 RGD:9068941
G Il13 interleukin 13 JBrowse link NW_004936647 2,529,933 2,532,503 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004936612 2,306,963 2,325,086 RGD:9068941
G Il6r interleukin 6 receptor JBrowse link NW_004936580 4,055,438 4,081,876 RGD:9068941
G Irak1 interleukin 1 receptor associated kinase 1 JBrowse link NW_004936809 891,407 900,311 RGD:9068941
G Irak4 interleukin 1 receptor associated kinase 4 JBrowse link NW_004936512 2,248,116 2,272,002 RGD:9068941
G Itga2 integrin subunit alpha 2 JBrowse link NW_004936480 14,320,292 14,417,828 RGD:9068941
G Itgb3 integrin subunit beta 3 JBrowse link NW_004936541 2,822,789 2,871,069 RGD:9068941
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link NW_004936522 3,034,364 3,037,632 RGD:9068941
G LOC101967032 cytochrome b-245 light chain JBrowse link NW_004936641 1,036,967 1,044,954 RGD:9068941
G Mmp2 matrix metallopeptidase 2 JBrowse link NW_004936475 7,801,356 7,825,831 RGD:9068941
G Mnat1 MNAT1 component of CDK activating kinase JBrowse link NW_004936495 4,909,427 5,128,113 RGD:9068941
G Mtor mechanistic target of rapamycin kinase JBrowse link NW_004936474 158,376 282,310 RGD:9068941
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004936560 2,797,943 2,828,813 RGD:9068941
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link NW_004936470 20,480,844 20,485,955 RGD:9068941
G Myd88 MYD88 innate immune signal transduction adaptor JBrowse link NW_004936473 27,672,237 27,676,339 RGD:9068941
G Nampt nicotinamide phosphoribosyltransferase JBrowse link NW_004936479 17,682,070 17,716,713 RGD:9068941
G Notch3 notch receptor 3 JBrowse link NW_004936596 5,265,984 5,301,430 RGD:9068941
G Nox1 NADPH oxidase 1 JBrowse link NW_004936584 6,023,960 6,040,041 RGD:9068941
G Npy5r neuropeptide Y receptor Y5 JBrowse link NW_004936555 2,248,699 2,252,637 RGD:9068941
G Nr4a3 nuclear receptor subfamily 4 group A member 3 JBrowse link NW_004936524 8,252,321 8,290,747 RGD:9068941
G Orc1 origin recognition complex subunit 1 JBrowse link NW_004936522 8,580,661 8,610,750 RGD:9068941
G Pde4d phosphodiesterase 4D JBrowse link NW_004936480 8,123,437 9,235,586 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004936492 2,353,840 2,368,573 RGD:9068941
G Pdgfd platelet derived growth factor D JBrowse link NW_004936551 3,974,140 4,197,852 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004936504 4,762,251 4,799,789 RGD:9068941
G Phb prohibitin JBrowse link NW_004936490 12,127,065 12,138,870 RGD:9068941
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004936566 3,924,013 3,951,052 RGD:9068941
G Ppargc1a PPARG coactivator 1 alpha JBrowse link NW_004936477 4,881,230 5,488,208 RGD:9068941
G Prkca protein kinase C alpha JBrowse link NW_004936541 6,231,604 6,488,201 RGD:9068941
G Ptafr platelet activating factor receptor JBrowse link NW_004936474 12,333,905 12,337,140 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004936481 3,821,564 3,828,086 RGD:9068941
G Ptk2 protein tyrosine kinase 2 JBrowse link NW_004936470 10,379,855 10,578,531 RGD:9068941
G Rab5a RAB5A, member RAS oncogene family JBrowse link NW_004936473 12,238,226 12,267,339 RGD:9068941
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link NW_004936477 3,354,336 3,445,248 RGD:9068941
G Retn resistin JBrowse link NW_004936588 4,705,295 4,706,653 RGD:9068941
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link NW_004936490 3,441,046 3,492,917 RGD:9068941
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link NW_004936748 1,244,962 1,250,093 RGD:9068941
G Serpinf2 serpin family F member 2 JBrowse link NW_004936538 7,870,898 7,877,279 RGD:9068941
G Shc1 SHC adaptor protein 1 JBrowse link NW_004936580 4,511,560 4,522,003 RGD:9068941
G Skp2 S-phase kinase associated protein 2 JBrowse link NW_004936518 5,635,856 5,664,057 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004936475 18,667,563 18,755,132 RGD:9068941
G Stat1 signal transducer and activator of transcription 1 JBrowse link NW_004936506 7,196,860 7,235,854 RGD:9068941
G Stat5b signal transducer and activator of transcription 5B JBrowse link NW_004936490 17,022,268 17,043,751 RGD:9068941
G Tgfbr2 transforming growth factor beta receptor 2 JBrowse link NW_004936473 21,324,669 21,409,430 RGD:9068941
G Tgm2 transglutaminase 2 JBrowse link NW_004936561 3,178,244 3,207,551 RGD:9068941
G Thbs1 thrombospondin 1 JBrowse link NW_004936471 3,064,466 3,081,125 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Traf6 TNF receptor associated factor 6 JBrowse link NW_004936533 1,857,685 1,874,973 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004936476 16,245,134 16,261,180 RGD:9068941
G Znf143 zinc finger protein 143 JBrowse link NW_004936528 8,614,393 8,676,301 RGD:9068941
positive regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 JBrowse link NW_004936640 959,405 967,305 RGD:9068941
G Agt angiotensinogen JBrowse link NW_004936484 19,713,299 19,721,144 RGD:9068941
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link NW_004936804 52,435 115,289 RGD:9068941
G Camk2d calcium/calmodulin dependent protein kinase II delta JBrowse link NW_004936563 4,226,412 4,526,139 RGD:9068941
G Ddx39b DExD-box helicase 39B JBrowse link NW_004936727 1,968,032 1,980,789 RGD:9068941
G Dnmt1 DNA methyltransferase 1 JBrowse link NW_004936659 520,181 565,496 RGD:9068941
G Edn1 endothelin 1 JBrowse link NW_004936534 885,489 892,292 RGD:9068941
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link NW_004936541 4,613,197 4,705,911 RGD:9068941
G Fgf2 fibroblast growth factor 2 JBrowse link NW_004936662 1,886,176 1,928,998 RGD:9068941
G Fgf9 fibroblast growth factor 9 JBrowse link NW_004936720 282,291 316,629 RGD:9068941
G Foxj2 forkhead box J2 JBrowse link NW_004936892 324,103 344,739 RGD:9068941
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link NW_004936545 7,286,018 7,407,623 RGD:9068941
G Gnai2 G protein subunit alpha i2 JBrowse link NW_004936529 1,779,582 1,801,251 RGD:9068941
G Gnai3 G protein subunit alpha i3 JBrowse link NW_004936704 1,031,476 1,075,662 RGD:9068941
G Grk2 G protein-coupled receptor kinase 2 JBrowse link NW_004936599 2,437,061 2,456,141 RGD:9068941
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link NW_004936516 5,551,192 5,578,796 RGD:9068941
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link NW_004936890 154,252 157,044 RGD:9068941
G Igf1 insulin like growth factor 1 JBrowse link NW_004936492 11,709,623 11,784,028 RGD:9068941
G Igfbp5 insulin like growth factor binding protein 5 JBrowse link NW_004936586 647,553 666,595 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link NW_004936522 3,034,364 3,037,632 RGD:9068941
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link NW_004936474 10,196,228 10,219,137 RGD:9068941
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link NW_004936560 3,988,696 4,197,953 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004936545 6,709,903 6,732,334 RGD:9068941
G Mef2d myocyte enhancer factor 2D JBrowse link NW_004936580 5,660,306 5,685,333 RGD:9068941
G Mfn2 mitofusin 2 JBrowse link NW_004936474 767,754 795,258 RGD:9068941
G Mmp2 matrix metallopeptidase 2 JBrowse link NW_004936475 7,801,356 7,825,831 RGD:9068941
G Mmp9 matrix metallopeptidase 9 JBrowse link NW_004936514 7,038,240 7,045,873 RGD:9068941
G Nr4a3 nuclear receptor subfamily 4 group A member 3 JBrowse link NW_004936524 8,252,321 8,290,747 RGD:9068941
G P2ry6 pyrimidinergic receptor P2Y6 JBrowse link NW_004936498 2,468,020 2,501,344 RGD:9068941
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link NW_004936498 6,001,126 6,135,663 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004936492 2,353,840 2,368,573 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Xbp1 X-box binding protein 1 JBrowse link NW_004936657 2,891,171 2,895,409 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11930
    positive regulation of biological process 5412
      positive regulation of cellular process 5013
        positive regulation of cell population proliferation 928
          positive regulation of smooth muscle cell proliferation 108
            positive regulation of vascular associated smooth muscle cell proliferation 35
Path 2
Term Annotations click to browse term
  biological_process 11930
    biological regulation 8730
      regulation of biological process 8292
        positive regulation of biological process 5412
          positive regulation of cellular process 5013
            positive regulation of cell population proliferation 928
              positive regulation of smooth muscle cell proliferation 108
                positive regulation of vascular associated smooth muscle cell proliferation 35
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.