ONTOLOGY REPORT - ANNOTATIONS
Term: sympathetic nervous system development
Accession: GO:0048485
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Definition: The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
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Ednra
endothelin receptor type A
involved_in
IEA ISO
GO_REF:0000107 MGI:2687362 (PMID:25197047)
Ensembl RGD
PMID:25197047
GO_REF:0000107
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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Erbb2
erb-b2 receptor tyrosine kinase 2
IMP
RGD
PMID:15496447
RGD:1358539
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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Gata3
GATA binding protein 3
acts_upstream_of_or_within
ISO
MGI:2153826 (PMID:15329349)
RGD
PMID:15329349
NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
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Gdnf
glial cell derived neurotrophic factor
involved_in
ISO IEA ISS
(PMID:8657308) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:8657308
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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Gfra3
GDNF family receptor alpha 3
acts_upstream_of_or_within
ISO
MGI:2136781|MGI:2183558 (PMID:10482239), (PMID:12160745)
RGD
PMID:10482239 PMID:12160745
NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
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Hand2
heart and neural crest derivatives expressed 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:16145670)
Ensembl RGD
PMID:16145670
GO_REF:0000107
NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891
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Nf1
neurofibromin 1
involved_in acts_upstream_of_or_within
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 MGI:1857444 (PMID:16906226), (PMID:7926784)
Ensembl HGNC-UCL RGD
PMID:7926784 PMID:16906226
GO_REF:0000024 GO_REF:0000107
NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
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Nrp1
neuropilin 1
acts_upstream_of_or_within
ISO
MGI:1857853 (PMID:15814794)
RGD
PMID:15814794
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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Ntrk1
neurotrophic receptor tyrosine kinase 1
involved_in
ISO ISS
(PMID:8815902) GO_REF:0000024
RGD UniProt
PMID:8815902
GO_REF:0000024
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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Phox2a
paired-like homeobox 2a
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2180328 (PMID:9115735)
Ensembl RGD
PMID:9115735
GO_REF:0000107
NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
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Phox2b
paired-like homeobox 2b
involved_in
ISO
(PMID:10360575)
RGD
PMID:10360575
NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978
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Plxna4
plexin A4
acts_upstream_of_or_within
ISO
MGI:3578655 (PMID:15814794)
RGD
PMID:15814794
NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
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Sox11
SRY-box transcription factor 11
involved_in
ISS ISO
GO_REF:0000024 (PMID:20147379)
UniProt RGD
PMID:20147379
GO_REF:0000024
NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
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Sox4
SRY-box transcription factor 4
involved_in
ISO
(PMID:20147379)
RGD
PMID:20147379
NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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Tfap2a
transcription factor AP-2 alpha
acts_upstream_of_or_within
ISO
MGI:104672 (PMID:21539825)
RGD
PMID:21539825
NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
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Tfap2b
transcription factor AP-2 beta
involved_in acts_upstream_of_or_within
ISS ISO
GO_REF:0000024 MGI:104671 (PMID:21539825)
UniProt RGD
PMID:21539825
GO_REF:0000024
NCBI chr 9:21,786,251...21,816,054
Ensembl chr 9:21,786,258...21,814,520
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Tp63
tumor protein p63
acts_upstream_of_or_within
ISO
MGI:1934580 (PMID:16337913)
RGD
PMID:16337913
NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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Sema3a
semaphorin 3A
involved_in
ISO
(PMID:19325129)
RGD
PMID:19325129
NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
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Ascl1
achaete-scute family bHLH transcription factor 1
involved_in
ISO ISS
(PMID:18094025) GO_REF:0000024
RGD UniProt
PMID:18094025
GO_REF:0000024
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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Ctnnb1
catenin beta 1
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:21325504) GO_REF:0000024
Ensembl RGD UniProt
PMID:21325504
GO_REF:0000024 GO_REF:0000107
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Fzd3
frizzled class receptor 3
involved_in
ISO
(PMID:21325504)
RGD
PMID:21325504
NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
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Insm1
INSM transcriptional repressor 1
involved_in
ISO
(PMID:18094025)
RGD
PMID:18094025
NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003
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Nrp1
neuropilin 1
involved_in
ISO
(PMID:19325129), (PMID:22790009)
RGD
PMID:19325129 PMID:22790009
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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Nrp2
neuropilin 2
involved_in
ISO IEA
(PMID:22790009) GO_REF:0000107
RGD Ensembl
PMID:22790009
GO_REF:0000107
NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
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Phox2b
paired-like homeobox 2b
involved_in
ISO
(PMID:18094025)
RGD
PMID:18094025
NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978
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Sema3a
semaphorin 3A
involved_in
ISO
(PMID:22790009)
RGD
PMID:22790009
NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
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Sema3f
semaphorin 3F
involved_in
ISO
(PMID:22790009)
RGD
PMID:22790009
NCBI chr 8:108,357,629...108,386,569
Ensembl chr 8:108,357,629...108,387,083
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