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ONTOLOGY REPORT - ANNOTATIONS


Term:sympathetic nervous system development
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Accession:GO:0048485 term browser browse the term
Definition:The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.



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sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in ISO
IEA
MGI:2687362 (MGI:5608725|PMID:25197047)
GO_REF:0000107
RGD
Ensembl
PMID:25197047 GO_REF:0000107 MGI:5608725 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:15496447 RGD:1358539 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2153826 (MGI:3578038|PMID:15329349)
UniProt
RGD
PMID:15329349 GO_REF:0000024 MGI:3578038 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:81285|PMID:8657308)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8657308 GO_REF:0000024 GO_REF:0000107 MGI:81285 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfra3 GDNF family receptor alpha 3 acts_upstream_of_or_within ISO MGI:2136781|MGI:2183558 (MGI:1344239|PMID:10482239), (MGI:2183092|PMID:12160745) RGD PMID:10482239 PMID:12160745 MGI:1344239 MGI:2183092 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3703388|PMID:16145670)
Ensembl
RGD
PMID:16145670 GO_REF:0000107 MGI:3703388 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:1857444 (MGI:3689139|PMID:16906226), (MGI:66069|PMID:7926784)
GO_REF:0000107
HGNC-UCL
RGD
Ensembl
PMID:7926784 PMID:16906226 GO_REF:0000024 GO_REF:0000107 MGI:3689139 MGI:66069 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:1857853 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:83009|PMID:8815902)
UniProt
RGD
PMID:8815902 GO_REF:0000024 MGI:83009 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180328 (MGI:86465|PMID:9115735)
Ensembl
RGD
PMID:9115735 GO_REF:0000107 MGI:86465 NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (MGI:1337891|PMID:10360575) RGD PMID:10360575 MGI:1337891 NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978
JBrowse link
G Plxna4 plexin A4 acts_upstream_of_or_within ISO MGI:3578655 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:4437361|PMID:20147379)
UniProt
RGD
PMID:20147379 GO_REF:0000024 MGI:4437361 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:4437361|PMID:20147379) RGD PMID:20147379 MGI:4437361 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:104672 (MGI:5049826|PMID:21539825) RGD PMID:21539825 MGI:5049826 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:104671 (MGI:5049826|PMID:21539825)
UniProt
RGD
PMID:21539825 GO_REF:0000024 MGI:5049826 NCBI chr 9:21,786,250...21,815,785
Ensembl chr 9:21,786,258...21,814,520
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934580 (MGI:3615730|PMID:16337913) RGD PMID:16337913 MGI:3615730 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
neural crest cell migration involved in sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sema3a semaphorin 3A involved_in ISO (MGI:5567908|PMID:19325129) RGD PMID:19325129 MGI:5567908 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
sympathetic ganglion development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772428|PMID:18094025)
UniProt
RGD
PMID:18094025 GO_REF:0000024 MGI:3772428 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:4941059|PMID:21325504)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21325504 GO_REF:0000024 GO_REF:0000107 MGI:4941059 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Fzd3 frizzled class receptor 3 involved_in ISO (MGI:4941059|PMID:21325504) RGD PMID:21325504 MGI:4941059 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5437554|PMID:22790009), (MGI:5567908|PMID:19325129) RGD PMID:19325129 PMID:22790009 MGI:5437554 MGI:5567908 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nrp2 neuropilin 2 involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978
JBrowse link
G Sema3a semaphorin 3A involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Sema3f semaphorin 3F involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 8:108,357,629...108,387,083
Ensembl chr 8:108,357,629...108,387,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    multicellular organismal process 9052
      multicellular organism development 5773
        system development 5413
          sympathetic nervous system development 24
            neural crest cell migration involved in sympathetic nervous system development 1
            sympathetic ganglion development 9
Path 2
Term Annotations click to browse term
  biological_process 19512
    developmental process 6931
      anatomical structure development 6346
        multicellular organism development 5773
          system development 5413
            nervous system development 2747
              autonomic nervous system development 58
                sympathetic nervous system development 24
                  neural crest cell migration involved in sympathetic nervous system development 1
                  sympathetic ganglion development 9
paths to the root