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ONTOLOGY REPORT - ANNOTATIONS


Term:sympathetic nervous system development
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Accession:GO:0048485 term browser browse the term
Definition:The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.


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sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:15496447 RGD:1358539 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2153826 (MGI:3578038|PMID:15329349)
UniProt
RGD
PMID:15329349 GO_REF:0000024 MGI:3578038 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:81285|PMID:8657308)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8657308 GO_REF:0000024 GO_REF:0000107 MGI:81285 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfra3 GDNF family receptor alpha 3 acts_upstream_of_or_within ISO MGI:2136781|MGI:2183558 (MGI:1344239|PMID:10482239), (MGI:2183092|PMID:12160745) RGD PMID:10482239 PMID:12160745 MGI:1344239 MGI:2183092 NCBI chr18:27,491,860...27,520,133
Ensembl chr18:27,491,845...27,520,295
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3703388|PMID:16145670)
Ensembl
RGD
PMID:16145670 GO_REF:0000107 MGI:3703388 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:1857444 (MGI:3689139|PMID:16906226), (MGI:66069|PMID:7926784)
GO_REF:0000107
HGNC-UCL
RGD
Ensembl
PMID:7926784 PMID:16906226 GO_REF:0000024 GO_REF:0000107 MGI:3689139 MGI:66069 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:1857853 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:83009|PMID:8815902)
UniProt
RGD
PMID:8815902 GO_REF:0000024 MGI:83009 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180328 (MGI:86465|PMID:9115735)
Ensembl
RGD
PMID:9115735 GO_REF:0000107 MGI:86465 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (MGI:1337891|PMID:10360575) RGD PMID:10360575 MGI:1337891 NCBI chr14:42,711,169...42,718,707
Ensembl chr14:42,714,315...42,717,010
JBrowse link
G Plxna4 plexin A4 acts_upstream_of_or_within ISO MGI:3578655 (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr 4:59,439,489...59,883,637
Ensembl chr 4:59,445,767...59,809,321
JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:4437361|PMID:20147379)
UniProt
RGD
PMID:20147379 GO_REF:0000024 MGI:4437361 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:4437361|PMID:20147379) RGD PMID:20147379 MGI:4437361 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:104672 (MGI:5049826|PMID:21539825) RGD PMID:21539825 MGI:5049826 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:104671 (MGI:5049826|PMID:21539825)
UniProt
RGD
PMID:21539825 GO_REF:0000024 MGI:5049826 NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934580 (MGI:3615730|PMID:16337913) RGD PMID:16337913 MGI:3615730 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
neural crest cell migration involved in sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sema3a semaphorin 3A involved_in ISO (MGI:5567908|PMID:19325129) RGD PMID:19325129 MGI:5567908 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
sympathetic ganglion development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772428|PMID:18094025)
UniProt
RGD
PMID:18094025 GO_REF:0000024 MGI:3772428 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:4941059|PMID:21325504)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21325504 GO_REF:0000024 GO_REF:0000107 MGI:4941059 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Fzd3 frizzled class receptor 3 involved_in ISO (MGI:4941059|PMID:21325504) RGD PMID:21325504 MGI:4941059 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr 3:140,427,961...140,430,467 JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5437554|PMID:22790009), (MGI:5567908|PMID:19325129) RGD PMID:19325129 PMID:22790009 MGI:5437554 MGI:5567908 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nrp2 neuropilin 2 involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr14:42,711,169...42,718,707
Ensembl chr14:42,714,315...42,717,010
JBrowse link
G Sema3a semaphorin 3A involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3f semaphorin 3F involved_in ISO (MGI:5437554|PMID:22790009) RGD PMID:22790009 MGI:5437554 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    multicellular organismal process 8912
      multicellular organism development 5740
        system development 5283
          sympathetic nervous system development 23
            neural crest cell migration involved in sympathetic nervous system development 1
            sympathetic ganglion development 9
Path 2
Term Annotations click to browse term
  biological_process 19633
    developmental process 6782
      anatomical structure development 6259
        multicellular organism development 5740
          system development 5283
            nervous system development 2717
              autonomic nervous system development 57
                sympathetic nervous system development 23
                  neural crest cell migration involved in sympathetic nervous system development 1
                  sympathetic ganglion development 9
paths to the root