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ONTOLOGY REPORT - ANNOTATIONS

Term:enteric nervous system development
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Accession:GO:0048484 term browser browse the term
Definition:The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.

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enteric nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arx aristaless related homeobox involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:62,363,757...62,376,139
Ensembl chr  X:62,363,757...62,376,143 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Ednrb endothelin receptor type B involved_in IGI
ISO		 (MGI:1330409|PMID:10021336) RGD PMID:10021336, PMID:15026112 MGI:1330409, RGD:1581884 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:81285|PMID:8657308), (MGI:81286|PMID:8657306)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:8657306 PMID:8657308 GO_REF:0000024 GO_REF:0000107 MGI:81285 MGI:81286 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:2182089 (MGI:3703127|PMID:16854219) RGD PMID:16854219 MGI:3703127 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223 		JBrowse link
G Isx intestine-specific homeobox involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:14,198,899...14,219,269
Ensembl chr19:14,198,899...14,218,531 		JBrowse link
G Kif26a kinesin family member 26A involved_in ISO (MGI:4410392|PMID:19914172) RGD PMID:19914172 MGI:4410392 NCBI chr 6:136,720,254...136,755,515
Ensembl chr 6:136,720,266...136,754,926 		JBrowse link
G LOC100364002 reproductive homeobox 9-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:123,999,683...124,002,081
Ensembl chr  X:123,999,683...124,002,073 		JBrowse link
G LOC691272 similar to reproductive homeobox on X chromosome, 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:124,045,727...124,052,708
Ensembl chr  X:124,045,737...124,052,632 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (MGI:3505802|PMID:15497153) RGD PMID:15497153 MGI:3505802 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886 		JBrowse link
G Phactr4 phosphatase and actin regulator 4 involved_in ISO (MGI:5302129|PMID:22215812) RGD PMID:22215812 MGI:5302129 NCBI chr 5:150,533,895...150,609,423
Ensembl chr 5:150,546,430...150,609,352 		JBrowse link
G Phox2a paired-like homeobox 2a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252 		JBrowse link
G Phox2b paired-like homeobox 2b involved_in IBA
ISO		 PMID:21873635
(MGI:1337891|PMID:10360575)
(PMID:12640453)		 RGD PMID:10360575 PMID:12640453, PMID:21873635 MGI:1337891, RGD:13792537 NCBI chr14:42,711,169...42,718,707
Ensembl chr14:42,714,315...42,717,010 		JBrowse link
G Ret ret proto-oncogene acts_upstream_of_or_within ISO MGI:2136894 (MGI:1313212|PMID:9834195) RGD PMID:9834195 MGI:1313212 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372 		JBrowse link
G Rhox10 reproductive homeobox 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:124,207,017...124,211,455
Ensembl chr  X:124,207,017...124,211,455 		JBrowse link
G Rhox11 Rhox homeobox family member 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:124,228,270...124,236,517
Ensembl chr  X:124,228,270...124,236,517 		JBrowse link
G Rhox12 Rhox homeobox family member 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:124,245,478...124,254,624
Ensembl chr  X:124,247,098...124,252,447 		JBrowse link
G Rhox13 Rhox homeobox family member 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:124,267,991...124,274,290
Ensembl chr  X:124,268,129...124,274,157 		JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:3527299|PMID:15572147)
MGI:1857401|MGI:3701358 (MGI:3701016|PMID:16790476), (MGI:56157|PMID:6512238)		 RGD PMID:6512238 PMID:15572147 PMID:16790476, PMID:21873635 MGI:3527299 MGI:3701016 MGI:56157, RGD:13792537 NCBI chr 7:120,393,238...120,403,523
Ensembl chr 7:120,393,254...120,403,523 		JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:3527299|PMID:15572147)
GO_REF:0000024		 RGD
UniProt		 PMID:15572147, PMID:21873635 GO_REF:0000024 MGI:3527299, RGD:13792537 NCBI chr10:14,932,348...14,937,336
Ensembl chr10:14,932,348...14,937,336 		JBrowse link
G Tlx2 T-cell leukemia homeobox 2 acts_upstream_of_or_within ISO MGI:2448951 (MGI:1095635|PMID:9259577) RGD PMID:9259577 MGI:1095635 NCBI chr 4:114,766,401...114,768,243
Ensembl chr 4:114,766,714...114,768,029
Ensembl chr 4:114,766,714...114,768,029 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    multicellular organismal process 8912
      multicellular organism development 5740
        system development 5283
          enteric nervous system development 21
Path 2
Term Annotations click to browse term
  biological_process 19633
    developmental process 6782
      anatomical structure development 6259
        multicellular organism development 5740
          system development 5283
            nervous system development 2717
              autonomic nervous system development 57
                enteric nervous system development 21
paths to the root