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ONTOLOGY REPORT - ANNOTATIONS

Term:enteric nervous system development
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Accession:GO:0048484 term browser browse the term
Definition:The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.


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enteric nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in ISO (MGI:1330409|PMID:10021336) RGD PMID:10021336 MGI:1330409 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:81285|PMID:8657308), (MGI:81286|PMID:8657306)		 Ensembl
UniProt
RGD		 PMID:8657306 PMID:8657308 GO_REF:0000024 GO_REF:0000107 MGI:81285 MGI:81286 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:2182089 (MGI:3703127|PMID:16854219) RGD PMID:16854219 MGI:3703127 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750 		JBrowse link
G Kif26a kinesin family member 26A involved_in ISO (MGI:4410392|PMID:19914172) RGD PMID:19914172 MGI:4410392 NCBI chr 6:131,214,839...131,250,874
Ensembl chr 6:131,214,861...131,250,320 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (MGI:3505802|PMID:15497153) RGD PMID:15497153 MGI:3505802 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Phactr4 phosphatase and actin regulator 4 involved_in ISO (MGI:5302129|PMID:22215812) RGD PMID:22215812 MGI:5302129 NCBI chr 5:144,549,350...144,621,259
Ensembl chr 5:144,549,363...144,620,865 		JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO
IBA		 (PMID:12640453)
(MGI:1337891|PMID:10360575)
PMID:21873635		 RGD PMID:10360575 PMID:12640453 PMID:21873635 MGI:1337891, RGD:13792537 NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978 		JBrowse link
G Ret ret proto-oncogene acts_upstream_of_or_within ISO MGI:2136894 (MGI:1313212|PMID:9834195) RGD PMID:9834195 MGI:1313212 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO (MGI:5810846|PMID:27111230) RGD PMID:27111230 MGI:5810846 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1857401|MGI:3701358 (MGI:3701016|PMID:16790476), (MGI:56157|PMID:6512238)
(MGI:3527299|PMID:15572147)		 RGD PMID:6512238 PMID:15572147 PMID:16790476 PMID:21873635 MGI:3527299 MGI:3701016 MGI:56157, RGD:13792537 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(MGI:3527299|PMID:15572147)		 UniProt
RGD		 PMID:15572147 PMID:21873635 GO_REF:0000024 MGI:3527299, RGD:13792537 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Tlx2 T-cell leukemia homeobox 2 acts_upstream_of_or_within ISO MGI:2448951 (MGI:1095635|PMID:9259577) RGD PMID:9259577 MGI:1095635 NCBI chr 4:115,573,736...115,576,097
Ensembl chr 4:115,573,799...115,575,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    multicellular organismal process 9177
      multicellular organism development 5184
        system development 4463
          enteric nervous system development 13
Path 2
Term Annotations click to browse term
  biological_process 19553
    developmental process 6909
      anatomical structure development 6435
        multicellular organism development 5184
          system development 4463
            nervous system development 2734
              autonomic nervous system development 51
                enteric nervous system development 13
paths to the root