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ONTOLOGY REPORT - ANNOTATIONS


Term:enteric nervous system development
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Accession:GO:0048484 term browser browse the term
Definition:The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.



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enteric nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B involved_in ISO (PMID:10021336) RGD PMID:10021336 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:8657306), (PMID:8657308)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:8657306 PMID:8657308 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:2182089 (PMID:16854219) RGD PMID:16854219 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Kif26a kinesin family member 26A involved_in ISO (PMID:19914172) RGD PMID:19914172 NCBI chr 6:131,214,839...131,250,874
Ensembl chr 6:131,214,861...131,250,320
JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (PMID:15497153) RGD PMID:15497153 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Phactr4 phosphatase and actin regulator 4 involved_in ISO (PMID:22215812) RGD PMID:22215812 NCBI chr 5:149,828,716...149,904,955
Ensembl chr 5:144,549,363...144,620,865
JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (PMID:12640453)
(PMID:10360575)
RGD PMID:10360575 PMID:12640453 NCBI chr14:41,420,011...41,424,527
Ensembl chr14:41,066,264...41,068,978
JBrowse link
G Ret ret proto-oncogene acts_upstream_of_or_within ISO MGI:2136894 (PMID:9834195) RGD PMID:9834195 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO (PMID:27111230) RGD PMID:27111230 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15572147)
MGI:1857401|MGI:3701358 (PMID:16790476), (PMID:6512238)
GO_Central
RGD
PMID:6512238 PMID:15572147 PMID:16790476 GO_REF:0000033 NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:15572147)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:15572147 GO_REF:0000024 GO_REF:0000033 NCBI chr10:15,089,357...15,094,345
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Tlx2 T-cell leukemia homeobox 2 acts_upstream_of_or_within ISO MGI:2448951 (PMID:9259577) RGD PMID:9259577 NCBI chr 4:117,131,516...117,133,359
Ensembl chr 4:115,573,799...115,575,642
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    multicellular organismal process 8969
      multicellular organism development 5330
        system development 4612
          enteric nervous system development 13
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            nervous system development 2862
              autonomic nervous system development 51
                enteric nervous system development 13
paths to the root