ONTOLOGY REPORT - ANNOTATIONS
Term: enteric nervous system development
Accession: GO:0048484
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Definition: The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
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Ednra
endothelin receptor type A
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049
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Ednrb
endothelin receptor type B
involved_in
ISO
(PMID:10021336)
RGD
PMID:10021336
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115
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Gdnf
glial cell derived neurotrophic factor
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:8657306), (PMID:8657308) GO_REF:0000024
Ensembl RGD UniProt
PMID:8657306 PMID:8657308
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209
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Hlx
H2.0-like homeobox
acts_upstream_of_or_within
ISO
MGI:2182089 (PMID:16854219)
RGD
PMID:16854219
NCBI chr13:98,811,852...98,817,264
Ensembl chr13:96,280,339...96,285,750
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Kif26a
kinesin family member 26A
involved_in
ISO
(PMID:19914172)
RGD
PMID:19914172
NCBI chr 6:131,214,839...131,250,874
Ensembl chr 6:131,214,861...131,250,320
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Ntf3
neurotrophin 3
acts_upstream_of_or_within
ISO
MGI:1933844 (PMID:15497153)
RGD
PMID:15497153
NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596
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Phactr4
phosphatase and actin regulator 4
involved_in
ISO
(PMID:22215812)
RGD
PMID:22215812
NCBI chr 5:149,828,716...149,904,955
Ensembl chr 5:144,549,363...144,620,865
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Phox2b
paired-like homeobox 2b
involved_in
ISO
(PMID:12640453) (PMID:10360575)
RGD
PMID:10360575 PMID:12640453
NCBI chr14:41,420,011...41,424,527
Ensembl chr14:41,066,264...41,068,978
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Ret
ret proto-oncogene
acts_upstream_of_or_within
ISO
MGI:2136894 (PMID:9834195)
RGD
PMID:9834195
NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176
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Slc6a4
solute carrier family 6 member 4
involved_in
ISO
(PMID:27111230)
RGD
PMID:27111230
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
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Sox10
SRY-box transcription factor 10
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:15572147) MGI:1857401|MGI:3701358 (PMID:16790476), (PMID:6512238)
GO_Central RGD
PMID:6512238 PMID:15572147 PMID:16790476
GO_REF:0000033
NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:110,725,274...110,735,544
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Sox8
SRY-box transcription factor 8
involved_in
ISS ISO IBA
GO_REF:0000024 (PMID:15572147) GO_REF:0000033
UniProt RGD GO_Central
PMID:15572147
GO_REF:0000024 GO_REF:0000033
NCBI chr10:15,089,357...15,094,345
Ensembl chr10:14,584,829...14,589,818
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Tlx2
T-cell leukemia homeobox 2
acts_upstream_of_or_within
ISO
MGI:2448951 (PMID:9259577)
RGD
PMID:9259577
NCBI chr 4:117,131,516...117,133,359
Ensembl chr 4:115,573,799...115,575,642
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