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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of isotype switching to IgG isotypes
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Accession:GO:0048302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: regulation of class switch recombination to IgG isotypes;   regulation of class switching to IgG isotypes;   regulation of isotype switch recombination to IgG isotypes



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regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16275384) Ensembl
MGI
PMID:16275384 GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11057672) Ensembl
MGI
PMID:11057672 GO_REF:0000107 NCBI chr 2:65,127,278...65,149,665
Ensembl chr 2:65,127,287...65,149,740
JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17137798) Ensembl
MGI
PMID:17137798 GO_REF:0000107 NCBI chr 2:143,688,946...143,734,523
Ensembl chr 2:143,629,783...143,734,520
JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25404367) Ensembl
MGI
PMID:25404367 GO_REF:0000107 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399
JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7688139) Ensembl
MGI
PMID:7688139 GO_REF:0000107 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,203...107,162,935
JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12882831) MGI
Ensembl
PMID:12882831 GO_REF:0000107 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670
JBrowse link
G IL2 interleukin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:1830926) Ensembl
MGI
PMID:1830926 GO_REF:0000107 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G MLH1 mutL homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757
JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837
JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:3,066,853...3,111,239
Ensembl chr18:3,066,848...3,111,240
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9015183) Ensembl
MGI
PMID:9015183 GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308
JBrowse link
G TBX21 T-box transcription factor 21 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12882831) Ensembl
MGI
PMID:12882831 GO_REF:0000107 NCBI chr12:23,996,415...24,009,353
Ensembl chr12:23,996,415...24,009,355
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18954
    immune system process 2582
      production of molecular mediator of immune response 246
        regulation of production of molecular mediator of immune response 212
          regulation of immunoglobulin production 87
            regulation of isotype switching 41
              regulation of isotype switching to IgG isotypes 17
                negative regulation of isotype switching to IgG isotypes 0
                positive regulation of isotype switching to IgG isotypes 13
Path 2
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      metabolic process 11730
        primary metabolic process 10388
          nucleobase-containing compound metabolic process 6336
            nucleic acid metabolic process 5821
              DNA metabolic process 907
                DNA recombination 321
                  somatic cell DNA recombination 79
                    somatic diversification of immune receptors via germline recombination within a single locus 79
                      somatic recombination of immunoglobulin gene segments 67
                        somatic recombination of immunoglobulin genes involved in immune response 59
                          isotype switching 59
                            regulation of isotype switching 41
                              regulation of isotype switching to IgG isotypes 17
                                negative regulation of isotype switching to IgG isotypes 0
                                positive regulation of isotype switching to IgG isotypes 13
paths to the root