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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of isotype switching to IgG isotypes
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Accession:GO:0048302 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
Synonyms:exact_synonym: regulation of class switch recombination to IgG isotypes;   regulation of class switching to IgG isotypes;   regulation of isotype switch recombination to IgG isotypes



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regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (PMID:16275384) RGD PMID:16275384 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO MGI:3525439 (PMID:11057672) RGD PMID:11057672 NCBI chr19:41,014,730...41,026,740
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3695433 (PMID:17137798)
Ensembl
RGD
PMID:17137798 GO_REF:0000107 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:25310967)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:25310967 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:7688139) RGD PMID:7688139 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:1830926) RGD PMID:1830926 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) RGD PMID:12882831 PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (PMID:10430621) RGD PMID:10430621 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9015183) RGD PMID:9015183 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (PMID:12882831) RGD PMID:12882831 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    immune system process 3120
      production of molecular mediator of immune response 249
        regulation of production of molecular mediator of immune response 216
          regulation of immunoglobulin production 88
            regulation of isotype switching 42
              regulation of isotype switching to IgG isotypes 17
                negative regulation of isotype switching to IgG isotypes 0
                positive regulation of isotype switching to IgG isotypes 13
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        primary metabolic process 10757
          nucleobase-containing compound metabolic process 5951
            nucleic acid metabolic process 5334
              DNA metabolic process 968
                DNA recombination 339
                  somatic cell DNA recombination 80
                    somatic diversification of immune receptors via germline recombination within a single locus 80
                      somatic recombination of immunoglobulin gene segments 68
                        somatic recombination of immunoglobulin genes involved in immune response 60
                          isotype switching 60
                            regulation of isotype switching 42
                              regulation of isotype switching to IgG isotypes 17
                                negative regulation of isotype switching to IgG isotypes 0
                                positive regulation of isotype switching to IgG isotypes 13
paths to the root