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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of isotype switching to IgE isotypes
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Accession:GO:0048294 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms:exact_synonym: down regulation of isotype switching to IgE isotypes;   downregulation of isotype switching to IgE isotypes;   negative regulation of class switch recombination to IgE isotypes;   negative regulation of class switching to IgE isotypes;   negative regulation of isotype switch recombination to IgE isotypes
 narrow_synonym: inhibition of isotype switching to IgE isotypes



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negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19896
    developmental process 7021
      negative regulation of developmental process 1104
        negative regulation of isotype switching 6
          negative regulation of isotype switching to IgE isotypes 3
Path 2
Term Annotations click to browse term
  biological_process 19896
    metabolic process 12209
      cellular metabolic process 9628
        cellular aromatic compound metabolic process 5912
          nucleobase-containing compound metabolic process 5679
            nucleic acid metabolic process 5183
              DNA metabolic process 1028
                DNA recombination 329
                  somatic cell DNA recombination 80
                    somatic diversification of immune receptors via germline recombination within a single locus 80
                      somatic recombination of immunoglobulin gene segments 68
                        somatic recombination of immunoglobulin genes involved in immune response 60
                          isotype switching 60
                            regulation of isotype switching 43
                              negative regulation of isotype switching 6
                                negative regulation of isotype switching to IgE isotypes 3
paths to the root