Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:lung alveolus development
go back to main search page
Accession:GO:0048286 term browser browse the term
Definition:The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
Synonyms:exact_synonym: alveolarization;   alveologenesis


show annotations for term's descendants           Sort by:
 
lung alveolus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in
NOT|acts_upstream_of_or_within
IEA
ISO
(MGI:3829841|PMID:18957418)
(MGI:3807143|PMID:18632686)
Ensembl
MGI
PMID:18632686 PMID:18957418 GO_REF:0000107 MGI:3807143 MGI:3829841 NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736
JBrowse link
G ACE angiotensin I converting enzyme ISO RGD PMID:22587910 RGD:6893470 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1861066|PMID:10899903) Ensembl
MGI
PMID:10899903 GO_REF:0000107 MGI:1861066 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:54141|PMID:937819) MGI PMID:937819 MGI:54141 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G ATXN1 ataxin 1 acts_upstream_of_or_within ISO (MGI:5298126|PMID:22014525) MGI PMID:22014525 MGI:5298126 NCBI chr35:15,458,498...15,863,829
Ensembl chr35:15,452,135...15,649,747
JBrowse link
G ATXN1L ataxin 1 like involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5298126|PMID:22014525) Ensembl
MGI
PMID:22014525 GO_REF:0000107 MGI:5298126 NCBI chr 5:77,616,484...77,627,411
Ensembl chr 5:77,619,861...77,621,924
JBrowse link
G B9D2 B9 domain containing 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3040752|PMID:12634787) Ensembl
MGI
PMID:12634787 GO_REF:0000107 MGI:3040752 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (PMID:8674409) MGI PMID:8674409 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G CIC capicua transcriptional repressor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5298126|PMID:22014525) Ensembl
MGI
PMID:22014525 GO_REF:0000107 MGI:5298126 NCBI chr 1:112,081,775...112,105,093
Ensembl chr 1:112,082,265...112,105,082
JBrowse link
G DBN1 drebrin 1 ISO RGD PMID:15928322 RGD:10398812 NCBI chr 4:35,899,969...35,913,015
Ensembl chr 4:35,889,392...35,912,507
JBrowse link
G EDN2 endothelin 2 acts_upstream_of_or_within ISO (MGI:5514104|PMID:23676500) MGI PMID:23676500 MGI:5514104 NCBI chr15:1,647,966...1,654,272
Ensembl chr15:1,648,077...1,654,272
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:61,621,964...61,636,152
Ensembl chr 5:61,622,550...61,636,148
JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (MGI:3716020|PMID:17560563)
(MGI:3688953|PMID:16989802)
MGI PMID:16989802 PMID:17560563 MGI:3688953 MGI:3716020 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (MGI:3688953|PMID:16989802) MGI PMID:16989802 MGI:3688953 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 acts_upstream_of_or_within ISO (MGI:5582954|PMID:24733830) MGI PMID:24733830 MGI:5582954 NCBI chr11:1,145,643...1,184,097
Ensembl chr11:1,145,585...1,185,165
JBrowse link
G FOXF1 forkhead box F1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2135612|PMID:11493558) Ensembl
MGI
PMID:11493558 GO_REF:0000107 MGI:2135612 NCBI chr 5:66,343,776...66,347,785
Ensembl chr 5:66,345,150...66,347,935
JBrowse link
G FOXP2 forkhead box P2 acts_upstream_of_or_within ISO (MGI:3710027|PMID:17428829) MGI PMID:17428829 MGI:3710027 NCBI chr14:53,311,214...53,864,056
Ensembl chr14:53,312,045...53,862,655
JBrowse link
G FZD1 frizzled class receptor 1 ISO RGD PMID:17911382 RGD:2304247 NCBI chr14:17,046,911...17,050,515
Ensembl chr14:17,047,382...17,049,337
JBrowse link
G HOPX HOP homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709528|PMID:16510470) Ensembl
MGI
PMID:16510470 GO_REF:0000107 MGI:3709528 NCBI chr13:48,829,161...48,854,502
Ensembl chr13:48,829,338...48,858,643
JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3606710|PMID:15295088), (MGI:3665532|PMID:17003488) Ensembl
MGI
PMID:15295088 PMID:17003488 GO_REF:0000107 MGI:3606710 MGI:3665532 NCBI chr14:40,315,409...40,319,001
Ensembl chr14:40,315,639...40,317,768
JBrowse link
G HS6ST1 heparan sulfate 6-O-sulfotransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3715036|PMID:17405882) MGI
Ensembl
PMID:17405882 GO_REF:0000107 MGI:3715036 NCBI chr19:22,343,193...22,372,464
Ensembl chr19:22,368,942...22,369,652
JBrowse link
G IGF1 insulin like growth factor 1 acts_upstream_of_or_within ISO (MGI:3640953|PMID:16691571) MGI PMID:16691571 MGI:3640953 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 involved_in ISO (MGI:3039207|PMID:15010534) BHF-UCL PMID:15010534 MGI:3039207 NCBI chr37:23,575,265...23,596,970
Ensembl chr37:23,579,841...23,596,870
JBrowse link
G ITGB6 integrin subunit beta 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3040752|PMID:12634787) Ensembl
MGI
PMID:12634787 GO_REF:0000107 MGI:3040752 NCBI chr36:5,833,206...5,962,699
Ensembl chr36:5,834,638...5,962,633
JBrowse link
G KDR kinase insert domain receptor acts_upstream_of_or_within ISO (MGI:2181852|PMID:12053176) MGI PMID:12053176 MGI:2181852 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3640953|PMID:16691571) Ensembl
MGI
PMID:16691571 GO_REF:0000107 MGI:3640953 NCBI chr26:23,400,226...23,418,538
Ensembl chr26:23,403,364...23,406,851
JBrowse link
G MAN1A2 mannosidase alpha class 1A member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3703634|PMID:17121831) Ensembl
MGI
PMID:17121831 GO_REF:0000107 MGI:3703634 NCBI chr17:54,697,507...54,908,305
Ensembl chr17:54,697,324...54,904,607
JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3652665|PMID:16754854) Ensembl
MGI
PMID:16754854 GO_REF:0000107 MGI:3652665 NCBI chr 3:2,340,392...2,477,458
Ensembl chr 3:2,330,959...2,488,393
JBrowse link
G MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within ISO (MGI:3796918|PMID:18324732) MGI PMID:18324732 MGI:3796918 NCBI chr 6:39,132,746...39,179,427
Ensembl chr 6:39,133,965...39,179,505
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:21425435 RGD:8552971 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3040752|PMID:12634787) Ensembl
MGI
PMID:12634787 GO_REF:0000107 MGI:3040752 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309
JBrowse link
G MYOCD myocardin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4941650|PMID:21357509) Ensembl
MGI
PMID:21357509 GO_REF:0000107 MGI:4941650 NCBI chr 5:36,674,476...36,774,435
Ensembl chr 5:36,674,300...36,769,327
JBrowse link
G PDGFA platelet derived growth factor subunit A involved_in
acts_upstream_of_or_within
ISO (MGI:1098909|PMID:9374392)
(MGI:5543868|PMID:23938297)
(MGI:3622881|PMID:11803579)
UniProt
MGI
PMID:9374392 PMID:11803579 PMID:23938297 MGI:1098909 MGI:3622881 MGI:5543868 NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396
JBrowse link
G PDPN podoplanin acts_upstream_of_or_within ISO (MGI:3703126|PMID:16869965) MGI PMID:16869965 MGI:3703126 NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375
JBrowse link
G PGR progesterone receptor acts_upstream_of_or_within ISO (MGI:5576858|PMID:24190884) MGI PMID:24190884 MGI:5576858 NCBI chr21:447,197...552,511
Ensembl chr21:447,319...552,511
JBrowse link
G PHF14 PHD finger protein 14 acts_upstream_of_or_within ISO (MGI:5426441|PMID:22730381) MGI PMID:22730381 MGI:5426441 NCBI chr14:25,907,955...26,089,666
Ensembl chr14:25,914,188...26,125,766
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892
JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (MGI:1346745|PMID:10518543) MGI PMID:10518543 MGI:1346745 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722
JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (MGI:3042805|PMID:15162506) MGI PMID:15162506 MGI:3042805 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5486592|PMID:23583643) Ensembl
MGI
PMID:23583643 GO_REF:0000107 MGI:5486592 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341
JBrowse link
G SELENON selenoprotein N acts_upstream_of_or_within ISO (MGI:5494499|PMID:23325319) MGI PMID:23325319 MGI:5494499 NCBI chr 2:74,134,448...74,149,585 JBrowse link
G SFTPD surfactant protein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:29,394,755...29,407,499
Ensembl chr 4:29,394,678...29,407,293
JBrowse link
G SLC7A11 solute carrier family 7 member 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5469541|PMID:23085521) Ensembl
MGI
PMID:23085521 GO_REF:0000107 MGI:5469541 NCBI chr19:4,289,792...4,379,060
Ensembl chr19:4,289,850...4,389,048
JBrowse link
G SLFN12 schlafen family member 12 ISO RGD PMID:17911382 RGD:2304247 NCBI chr 9:38,140,071...38,146,347 JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5469952|PMID:22945695) Ensembl
MGI
PMID:22945695 GO_REF:0000107 MGI:5469952 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189
JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (MGI:3795352|PMID:18374910) MGI PMID:18374910 MGI:3795352 NCBI chr34:14,853,000...14,855,153 JBrowse link
G STK40 serine/threonine kinase 40 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5486391|PMID:23293024) Ensembl
MGI
PMID:23293024 GO_REF:0000107 MGI:5486391 NCBI chr15:5,894,125...5,934,461
Ensembl chr15:5,894,933...5,932,791
JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in ISO (PMID:17273977) DFLAT PMID:17273977 NCBI chr30:37,331,834...37,359,449
Ensembl chr30:37,331,832...37,353,529
JBrowse link
G TCF21 transcription factor 21 involved_in
acts_upstream_of_or_within
ISS
ISO
(MGI:1347485|PMID:10572052) UniProt
MGI
PMID:10572052 GO_REF:0000024 MGI:1347485 NCBI chr 1:26,856,281...26,859,654
Ensembl chr 1:26,856,587...26,859,647
JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TGFB3 transforming growth factor beta 3 involved_in ISO (MGI:77427|PMID:7493022) BHF-UCL PMID:7493022 MGI:77427 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816
JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3850579|PMID:19515693) Ensembl
MGI
PMID:19515693 GO_REF:0000107 MGI:3850579 NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556
JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 acts_upstream_of_or_within ISO (MGI:5300435|PMID:21956870) MGI PMID:21956870 MGI:5300435 NCBI chr15:29,280,423...29,350,449
Ensembl chr15:29,298,078...29,350,553
JBrowse link
G TNS3 tensin 3 acts_upstream_of_or_within ISO (MGI:3531231|PMID:15733665) MGI PMID:15733665 MGI:3531231 NCBI chr16:279,468...432,911
Ensembl chr16:278,957...431,704
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:16230500 RGD:1580552 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G WNT5A Wnt family member 5A ISO RGD PMID:17911382 RGD:2304247 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
G ZNF157 zinc finger protein 157 acts_upstream_of_or_within ISO (MGI:5424261|PMID:22588720) MGI PMID:22588720 MGI:5424261 NCBI chr  X:40,952,543...41,005,828
Ensembl chr  X:40,952,636...41,005,133
JBrowse link
alveolar primary septum development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:37,331,834...37,359,449
Ensembl chr30:37,331,832...37,353,529
JBrowse link
alveolar secondary septum development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (MGI:1309575|PMID:9716527) MGI PMID:9716527 MGI:1309575 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO (MGI:1309575|PMID:9716527) MGI PMID:9716527 MGI:1309575 NCBI chr 4:36,243,689...36,254,636
Ensembl chr 4:36,244,220...36,252,035
JBrowse link
G FOXA1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3613241|PMID:16214823) Ensembl
MGI
PMID:16214823 GO_REF:0000107 MGI:3613241 NCBI chr 8:16,072,629...16,083,105
Ensembl chr 8:16,079,140...16,083,807
JBrowse link
lung saccule development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASXL1 ASXL transcriptional regulator 1 acts_upstream_of_or_within ISO (MGI:5585348|PMID:24860998) MGI PMID:24860998 MGI:5585348 NCBI chr24:21,725,126...21,804,745
Ensembl chr24:21,661,059...21,802,815
JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4950818|PMID:21408140) Ensembl
MGI
PMID:21408140 GO_REF:0000107 MGI:4950818 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:3695537|PMID:17164424) MGI PMID:17164424 MGI:3695537 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (MGI:3584290|PMID:16049328) MGI PMID:16049328 MGI:3584290 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3695537|PMID:17164424) Ensembl
MGI
PMID:17164424 GO_REF:0000107 MGI:3695537
G PTGES3 prostaglandin E synthase 3 acts_upstream_of_or_within ISO (MGI:3714109|PMID:17438133) MGI PMID:17438133 MGI:3714109 NCBI chr10:885,744...903,814
Ensembl chr10:870,392...909,161
JBrowse link
positive regulation of lung alveolus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:23962064 RGD:10395379 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16218
    developmental process 6406
      anatomical structure development 5951
        lung alveolus development 68
          lung saccule development + 11
          negative regulation of lung alveolus development 0
          positive regulation of lung alveolus development 1
          regulation of lung alveolus development + 1
Path 2
Term Annotations click to browse term
  biological_process 16218
    developmental process 6406
      anatomical structure development 5951
        multicellular organism development 5437
          system development 5067
            animal organ development 3893
              respiratory tube development 268
                lung development 265
                  lung alveolus development 68
                    lung saccule development + 11
                    negative regulation of lung alveolus development 0
                    positive regulation of lung alveolus development 1
                    regulation of lung alveolus development + 1
paths to the root