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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of receptor-mediated endocytosis
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Accession:GO:0048261 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms:exact_synonym: down regulation of receptor mediated endocytosis;   downregulation of receptor mediated endocytosis
 narrow_synonym: inhibition of receptor mediated endocytosis


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negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C-I involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chr 7:19,689,480...19,692,659
Ensembl chr 7:19,689,481...19,692,660
JBrowse link
G Apoc2 apolipoprotein C-II involved_in ISO (PMID:1917954) MGI
BHF-UCL
PMID:1917954 GO_REF:0000096 MGI:4834177 NCBI chr 7:19,671,579...19,677,941
Ensembl chr 7:19,671,579...19,677,941
JBrowse link
G Apoc3 apolipoprotein C-III involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chr 9:46,233,050...46,235,636
Ensembl chr 9:46,232,933...46,235,636
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO (PMID:10436022) MGI
BHF-UCL
PMID:10436022 GO_REF:0000096 MGI:4834177 NCBI chr 7:90,130,192...90,209,447
Ensembl chr 7:90,130,213...90,213,465
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 IMP (MGI:3620385|PMID:16533754) MGI PMID:16533754 MGI:3620385 NCBI chr 5:130,171,819...130,214,342
Ensembl chr 5:130,171,798...130,214,342
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neu3 neuraminidase 3 involved_in ISO (PMID:26251452) MGI
UniProt
PMID:26251452 GO_REF:0000096 MGI:4834177 NCBI chr 7:99,811,434...99,828,457
Ensembl chr 7:99,811,439...99,828,417
JBrowse link
G Sh3gl3 SH3-domain GRB2-like 3 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 7:82,173,808...82,307,420
Ensembl chr 7:82,173,840...82,307,419
JBrowse link
G Syt11 synaptotagmin XI ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 3:88,744,699...88,775,159
Ensembl chr 3:88,744,700...88,775,164
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) MGI
UniProt
PMID:18199683 GO_REF:0000096 MGI:4834177 NCBI chr  X:153,498,232...153,501,562
Ensembl chr  X:153,498,227...153,501,570
JBrowse link
G Unc119 unc-119 lipid binding chaperone IMP
IBA
(MGI:5559669|PMID:19781630)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:19781630 PMID:21873635 MGI:5559669 MGI:6201960 NCBI chr11:78,343,495...78,349,164
Ensembl chr11:78,343,482...78,349,164
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) MGI
UniProt
PMID:17689978 GO_REF:0000096 MGI:4834177 NCBI chr 8:119,446,719...119,472,640
Ensembl chr 8:119,446,719...119,472,640
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) MGI
UniProt
PMID:18199683 GO_REF:0000096 MGI:4834177 NCBI chr  X:153,498,232...153,501,562
Ensembl chr  X:153,498,227...153,501,570
JBrowse link
negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of ISO
IDA
(PMID:21810484)
(MGI:5306885|PMID:21810484)
MGI
ARUK-UCL
ARUK-UCL
PMID:21810484 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:5306885 RGD:14697730 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of ISO (PMID:11222466) MGI
BHF-UCL
PMID:11222466 GO_REF:0000096 MGI:4834177 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G App amyloid beta (A4) precursor protein NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Itgav integrin alpha V acts_upstream_of_or_within ISO (PMID:15215180) MGI
BHF-UCL
PMID:15215180 GO_REF:0000096 MGI:4834177 NCBI chr 2:83,722,303...83,806,917
Ensembl chr 2:83,724,397...83,806,916
JBrowse link
G Itgb3 integrin beta 3 acts_upstream_of_or_within ISO (PMID:15215180) MGI
BHF-UCL
PMID:15215180 GO_REF:0000096 MGI:4834177 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) MGI
BHF-UCL
PMID:22848640 GO_REF:0000096 MGI:4834177 NCBI chr 4:106,442,334...106,464,325
Ensembl chr 4:106,442,329...106,464,329
JBrowse link
G Psen1 presenilin 1 NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr12:83,688,152...83,735,095
Ensembl chr12:83,688,152...83,735,199
JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13a ankyrin repeat domain 13a involved_in ISO (PMID:22298428) MGI
UniProt
PMID:22298428 GO_REF:0000096 MGI:4834177 NCBI chr 5:114,774,948...114,805,821
Ensembl chr 5:114,774,677...114,806,200
JBrowse link
G Ankrd13b ankyrin repeat domain 13b involved_in ISO (PMID:22298428) MGI
UniProt
PMID:22298428 GO_REF:0000096 MGI:4834177 NCBI chr11:77,470,485...77,490,042
Ensembl chr11:77,470,485...77,489,678
JBrowse link
G Ankrd13d ankyrin repeat domain 13 family, member D involved_in ISO (PMID:22298428) MGI
UniProt
PMID:22298428 GO_REF:0000096 MGI:4834177 NCBI chr19:4,270,180...4,284,053
Ensembl chr19:4,270,180...4,283,137
JBrowse link
G Atxn2 ataxin 2 involved_in ISO (PMID:18602463) MGI
UniProt
PMID:18602463 GO_REF:0000096 MGI:4834177 NCBI chr 5:121,711,609...121,814,950
Ensembl chr 5:121,711,337...121,816,493
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in ISO PMID:11526121 MGI
UniProt
PMID:11526121 GO_REF:0000096 MGI:4417868 RGD:8554437 NCBI chr11:70,017,203...70,045,535
Ensembl chr11:70,016,942...70,047,522
JBrowse link
G Fmr1 FMRP translational regulator 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr  X:68,678,536...68,717,963
Ensembl chr  X:68,678,541...68,717,963
JBrowse link
G Lrpap1 low density lipoprotein receptor-related protein associated protein 1 involved_in ISO
IBA
(PMID:23386614)
(MGI:6201960|PMID:21873635)
MGI
ARUK-UCL
GO_Central
PMID:21873635 PMID:23386614 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 5:35,091,490...35,105,699
Ensembl chr 5:35,091,501...35,105,766
JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 IGI (MGI:5515239|PMID:23931994) MGI PMID:23931994 MGI:5515239 NCBI chr 6:77,229,210...77,259,915
Ensembl chr 6:77,242,689...77,257,791
JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 IGI (MGI:5515239|PMID:23931994) MGI PMID:23931994 MGI:5515239 NCBI chr18:35,209,003...35,215,024
Ensembl chr18:35,209,003...35,215,024
JBrowse link
G Mtmr2 myotubularin related protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:13,747,260...13,808,896
Ensembl chr 9:13,748,410...13,806,481
JBrowse link
G Rin3 Ras and Rab interactor 3 acts_upstream_of_or_within ISO (PMID:23185384) MGI
ARUK-UCL
PMID:23185384 GO_REF:0000096 MGI:4834177 NCBI chr12:102,282,840...102,390,854
Ensembl chr12:102,283,048...102,390,855
JBrowse link
G Sdcbp syndecan binding protein involved_in ISO (PMID:25893292) MGI
UniProt
PMID:25893292 GO_REF:0000096 MGI:4834177 NCBI chr 4:6,365,680...6,396,122
Ensembl chr 4:6,365,650...6,408,423
JBrowse link
G Wdr54 WD repeat domain 54 involved_in ISO (PMID:30458214) MGI
UniProt
PMID:30458214 GO_REF:0000096 MGI:4834177 NCBI chr 6:83,152,710...83,156,524
Ensembl chr 6:83,149,361...83,156,397
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of ISO (PMID:21810484) MGI
ARUK-UCL
PMID:21810484 GO_REF:0000096 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) MGI
BHF-UCL
PMID:22848640 GO_REF:0000096 MGI:4834177 NCBI chr 4:106,442,334...106,464,325
Ensembl chr 4:106,442,329...106,464,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23334
    negative regulation of biological process 5685
      negative regulation of transport 522
        negative regulation of endocytosis 50
          negative regulation of receptor-mediated endocytosis 31
            negative regulation of clathrin-dependent endocytosis 5
            negative regulation of low-density lipoprotein receptor activity 7
            negative regulation of receptor internalization + 15
            negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
Path 2
Term Annotations click to browse term
  biological_process 23334
    localization 6249
      establishment of localization 4679
        transport 4518
          vesicle-mediated transport 1613
            endocytosis 673
              receptor-mediated endocytosis 260
                regulation of receptor-mediated endocytosis 128
                  negative regulation of receptor-mediated endocytosis 31
                    negative regulation of clathrin-dependent endocytosis 5
                    negative regulation of low-density lipoprotein receptor activity 7
                    negative regulation of receptor internalization + 15
                    negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
paths to the root