Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of receptor-mediated endocytosis
go back to main search page
Accession:GO:0048261 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms:exact_synonym: down regulation of receptor mediated endocytosis;   downregulation of receptor mediated endocytosis
 narrow_synonym: inhibition of receptor mediated endocytosis


show annotations for term's descendants           Sort by:
 
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in IDA (PMID:1917954) BHF-UCL PMID:1917954 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
JBrowse link
G APOC2 apolipoprotein C2 involved_in IDA (PMID:1917954) BHF-UCL PMID:1917954 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,945,971...44,949,566
Ensembl chr19:44,945,971...44,949,566
JBrowse link
G APOC3 apolipoprotein C3 involved_in IDA (PMID:1917954) BHF-UCL PMID:1917954 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G ARF6 ADP ribosylation factor 6 involved_in TAS (PMID:9312003) UniProt PMID:9312003 NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,082...49,897,054
JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IDA (PMID:10436022) BHF-UCL PMID:10436022 NCBI chr11:85,957,175...86,069,860
Ensembl chr11:85,957,175...86,069,882
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3620385|PMID:16533754) MGI PMID:16533754 MGI:3620385 NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in TAS (PMID:9312003) UniProt PMID:9312003 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEU3 neuraminidase 3 involved_in IDA (PMID:26251452) UniProt PMID:26251452 NCBI chr11:74,988,644...75,010,907
Ensembl chr11:74,988,279...75,018,893
JBrowse link
G SH3GL3 SH3 domain containing GRB2 like 3, endophilin A3 involved_in IEA
ISO
Ensembl
RGD
PMID:15066995 GO_REF:0000107 RGD:13504745 NCBI chr15:83,447,123...83,618,743
Ensembl chr15:83,447,228...83,618,743
JBrowse link
G SYT11 synaptotagmin 11 involved_in IEA
ISO
PMID:26589353 Ensembl
ParkinsonsUK-UCL
PMID:26589353 GO_REF:0000107 RGD:11079192 NCBI chr 1:155,859,502...155,885,199
Ensembl chr 1:155,859,567...155,885,199
JBrowse link
G UBQLN2 ubiquilin 2 involved_in IMP (PMID:18199683) UniProt PMID:18199683 NCBI chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868
JBrowse link
G UNC119 unc-119 lipid binding chaperone involved_in ISS
ISO
IBA
(MGI:5559669|PMID:19781630)
(PMID:21873635)
UniProt
UniProt
GO_Central
PMID:19781630 PMID:21873635 GO_REF:0000024 MGI:5559669 NCBI chr17:28,546,707...28,552,633
Ensembl chr17:28,546,708...28,552,631
Ensembl chr17:28,546,708...28,552,631
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECAB2 N-terminal EF-hand calcium binding protein 2 involved_in IDA (PMID:17689978) UniProt PMID:17689978 NCBI chr16:83,968,244...84,002,776
Ensembl chr16:83,968,632...84,002,776
JBrowse link
G UBQLN2 ubiquilin 2 involved_in IMP (PMID:18199683) UniProt PMID:18199683 NCBI chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868
JBrowse link
negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA
ISO
(PMID:21810484)
(MGI:5306885|PMID:21810484)
ARUK-UCL
ARUK-UCL
PMID:21810484 MGI:5306885 RGD:14697730 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing acts_upstream_of IDA (PMID:11222466) BHF-UCL PMID:11222466 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G APP amyloid beta precursor protein NOT|involved_in IGI (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ITGAV integrin subunit alpha V acts_upstream_of_or_within IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,056...186,680,901
JBrowse link
G ITGB3 integrin subunit beta 3 acts_upstream_of_or_within IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
G PSEN1 presenilin 1 NOT|involved_in IGI (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD13A ankyrin repeat domain 13A involved_in IMP (PMID:22298428) UniProt PMID:22298428 NCBI chr12:109,999,169...110,039,763
Ensembl chr12:109,999,186...110,039,763
JBrowse link
G ANKRD13B ankyrin repeat domain 13B involved_in IMP (PMID:22298428) UniProt PMID:22298428 NCBI chr17:29,589,769...29,615,006
Ensembl chr17:29,589,769...29,614,761
JBrowse link
G ANKRD13D ankyrin repeat domain 13D involved_in IMP (PMID:22298428) UniProt PMID:22298428 NCBI chr11:67,289,303...67,302,484
Ensembl chr11:67,289,300...67,302,485
Ensembl chr11:67,289,300...67,302,485
JBrowse link
G ATXN2 ataxin 2 involved_in IMP (PMID:18602463) UniProt PMID:18602463 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 involved_in ISS
ISO
PMID:11526121 BHF-UCL
UniProt
PMID:11526121 GO_REF:0000024 RGD:8554437 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
Ensembl chr17:7,189,890...7,219,841
JBrowse link
G FMR1 FMRP translational regulator 1 ISO RGD PMID:17881561 RGD:12050150 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,951...147,951,125
Ensembl chr  X:147,911,951...147,951,125
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 involved_in IGI
IBA
(PMID:23386614)
(PMID:21873635)
ARUK-UCL
GO_Central
PMID:21873635 PMID:23386614 NCBI chr 4:3,503,612...3,532,497
Ensembl chr 4:3,503,612...3,532,446
JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 ISO (MGI:5515239|PMID:23931994) MGI PMID:23931994 MGI:5515239 NCBI chr 2:80,301,878...80,304,752
Ensembl chr 2:80,288,351...80,304,752
JBrowse link
G LRRTM2 leucine rich repeat transmembrane neuronal 2 involved_in IEA
ISO
(MGI:5515239|PMID:23931994) Ensembl
MGI
PMID:23931994 GO_REF:0000107 MGI:5515239 NCBI chr 5:138,868,921...138,875,335
Ensembl chr 5:138,868,921...138,875,368
JBrowse link
G MTMR2 myotubularin related protein 2 involved_in ISS
ISO
PMID:20410104 BHF-UCL
BHF-UCL
PMID:20410104 GO_REF:0000024 RGD:8553482 NCBI chr11:95,832,880...95,924,110
Ensembl chr11:95,821,766...95,925,315
Ensembl chr11:95,821,766...95,925,315
Ensembl chr11:95,821,766...95,925,315
JBrowse link
G RIN3 Ras and Rab interactor 3 acts_upstream_of_or_within IMP (PMID:23185384) ARUK-UCL PMID:23185384 NCBI chr14:92,513,773...92,688,994
Ensembl chr14:92,513,781...92,688,994
JBrowse link
G SDCBP syndecan binding protein involved_in IMP (PMID:25893292) UniProt PMID:25893292 NCBI chr 8:58,553,261...58,582,860
Ensembl chr 8:58,552,924...58,582,859
JBrowse link
G WDR54 WD repeat domain 54 involved_in IMP (PMID:30458214) UniProt PMID:30458214 NCBI chr 2:74,421,721...74,426,259
Ensembl chr 2:74,421,678...74,425,755
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18684
    negative regulation of biological process 6319
      negative regulation of transport 543
        negative regulation of endocytosis 54
          negative regulation of receptor-mediated endocytosis 33
            negative regulation of clathrin-dependent endocytosis 5
            negative regulation of low-density lipoprotein receptor activity 7
            negative regulation of receptor internalization + 15
            negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
Path 2
Term Annotations click to browse term
  biological_process 18684
    localization 7251
      establishment of localization 5648
        transport 5496
          vesicle-mediated transport 2324
            endocytosis 765
              receptor-mediated endocytosis 373
                regulation of receptor-mediated endocytosis 132
                  negative regulation of receptor-mediated endocytosis 33
                    negative regulation of clathrin-dependent endocytosis 5
                    negative regulation of low-density lipoprotein receptor activity 7
                    negative regulation of receptor internalization + 15
                    negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
paths to the root