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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of receptor-mediated endocytosis
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Accession:GO:0048261 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms:exact_synonym: down regulation of receptor mediated endocytosis;   downregulation of receptor mediated endocytosis
 narrow_synonym: inhibition of receptor mediated endocytosis


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negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:1917954) BHF-UCL PMID:1917954 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO (PMID:10436022) BHF-UCL PMID:10436022 NCBI chrNW_004955414:6,871,220...6,970,569
Ensembl chrNW_004955414:6,871,520...6,969,208
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3620385|PMID:16533754) MGI PMID:16533754 MGI:3620385 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821
JBrowse link
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neu3 neuraminidase 3 involved_in ISO (PMID:26251452) UniProt PMID:26251452 NCBI chrNW_004955414:16,783,996...16,798,368
Ensembl chrNW_004955414:16,788,171...16,798,535
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 ISO RGD PMID:15066995 RGD:13504745 NCBI chrNW_004955416:13,151,288...13,297,878
Ensembl chrNW_004955416:13,150,021...13,297,878
JBrowse link
G Syt11 synaptotagmin 11 ISO PMID:26589353 ParkinsonsUK-UCL PMID:26589353 RGD:11079192 NCBI chrNW_004955545:2,054,720...2,074,526
Ensembl chrNW_004955545:2,054,721...2,074,526
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) UniProt PMID:18199683 NCBI chrNW_004955475:3,260,209...3,263,586
Ensembl chrNW_004955475:3,260,503...3,262,380
JBrowse link
G Unc119 unc-119 lipid binding chaperone ISO (MGI:5559669|PMID:19781630) UniProt PMID:19781630 MGI:5559669 NCBI chrNW_004955481:4,597,839...4,603,313
Ensembl chrNW_004955481:4,597,839...4,603,313
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) UniProt PMID:17689978 NCBI chrNW_004955564:257,781...279,937
Ensembl chrNW_004955564:258,222...277,889
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) UniProt PMID:18199683 NCBI chrNW_004955475:3,260,209...3,263,586
Ensembl chrNW_004955475:3,260,503...3,262,380
JBrowse link
negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:21810484
(PMID:21810484)
(MGI:5306885|PMID:21810484)
ARUK-UCL PMID:21810484 MGI:5306885 RGD:14697730 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of ISO (PMID:11222466) BHF-UCL PMID:11222466 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G App amyloid beta precursor protein NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Itgav integrin subunit alpha V acts_upstream_of_or_within ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chrNW_004955403:11,588,536...11,669,809
Ensembl chrNW_004955403:11,592,339...11,659,297
JBrowse link
G Itgb3 integrin subunit beta 3 acts_upstream_of_or_within ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chrNW_004955478:9,788,192...9,830,254 JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842
JBrowse link
G Psen1 presenilin 1 NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
JBrowse link
negative regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13a ankyrin repeat domain 13A involved_in ISO (PMID:22298428) UniProt PMID:22298428 NCBI chrNW_004955455:8,576,406...8,610,878
Ensembl chrNW_004955455:8,576,406...8,610,995
JBrowse link
G Ankrd13b ankyrin repeat domain 13B involved_in ISO (PMID:22298428) UniProt PMID:22298428 NCBI chrNW_004955481:3,644,332...3,662,375
Ensembl chrNW_004955481:3,644,332...3,661,895
JBrowse link
G Ankrd13d ankyrin repeat domain 13D involved_in ISO (PMID:22298428) UniProt PMID:22298428 NCBI chrNW_004955422:18,159,337...18,170,480
Ensembl chrNW_004955422:18,159,337...18,170,480
JBrowse link
G Atxn2 ataxin 2 involved_in ISO (PMID:18602463) UniProt PMID:18602463 NCBI chrNW_004955482:8,101,410...8,187,815
Ensembl chrNW_004955482:8,101,917...8,216,219
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in ISO PMID:11526121 UniProt PMID:11526121 RGD:8554437 NCBI chrNW_004955467:9,691,733...9,715,872
Ensembl chrNW_004955467:9,690,469...9,715,872
JBrowse link
G Fmr1 FMRP translational regulator 1 ISO RGD PMID:17881561 RGD:12050150 NCBI chrNW_004955498:566,741...594,837
Ensembl chrNW_004955498:566,688...595,360
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 involved_in ISO (PMID:23386614) ARUK-UCL PMID:23386614 NCBI chrNW_004955514:2,195,228...2,208,258
Ensembl chrNW_004955514:2,195,228...2,208,688
JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 ISO (MGI:5515239|PMID:23931994) MGI PMID:23931994 MGI:5515239 NCBI chrNW_004955424:6,322,284...6,337,550
Ensembl chrNW_004955424:6,322,284...6,337,550
JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 ISO (MGI:5515239|PMID:23931994) MGI PMID:23931994 MGI:5515239 NCBI chrNW_004955418:1,636,906...1,643,430
Ensembl chrNW_004955418:1,636,828...1,643,588
JBrowse link
G Mtmr2 myotubularin related protein 2 ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chrNW_004955412:693,743...764,377
Ensembl chrNW_004955412:693,743...750,154
JBrowse link
G Rin3 Ras and Rab interactor 3 acts_upstream_of_or_within ISO (PMID:23185384) ARUK-UCL PMID:23185384 NCBI chrNW_004955438:14,777,866...14,898,572
Ensembl chrNW_004955438:14,778,262...14,898,747
JBrowse link
G Sdcbp syndecan binding protein involved_in ISO (PMID:25893292) UniProt PMID:25893292 NCBI chrNW_004955454:17,093,930...17,113,491
Ensembl chrNW_004955454:17,089,232...17,113,484
JBrowse link
G Wdr54 WD repeat domain 54 involved_in ISO (PMID:30458214) UniProt PMID:30458214 NCBI chrNW_004955424:11,358,694...11,362,138
Ensembl chrNW_004955424:11,358,694...11,362,053
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11940
    negative regulation of biological process 4636
      negative regulation of transport 484
        negative regulation of endocytosis 48
          negative regulation of receptor-mediated endocytosis 31
            negative regulation of clathrin-dependent endocytosis 5
            negative regulation of low-density lipoprotein receptor activity 7
            negative regulation of receptor internalization + 15
            negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
Path 2
Term Annotations click to browse term
  biological_process 11940
    localization 4785
      establishment of localization 3423
        transport 3263
          vesicle-mediated transport 1124
            endocytosis 409
              receptor-mediated endocytosis 227
                regulation of receptor-mediated endocytosis 122
                  negative regulation of receptor-mediated endocytosis 31
                    negative regulation of clathrin-dependent endocytosis 5
                    negative regulation of low-density lipoprotein receptor activity 7
                    negative regulation of receptor internalization + 15
                    negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
paths to the root