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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of receptor-mediated endocytosis
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Accession:GO:0048259 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.


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regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd2ap CD2-associated protein JBrowse link 9 20,794,680 20,858,438 RGD:1302417
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1624291
RGD:13792537
RGD:1600115
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1601478
negative regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 JBrowse link 1 144,069,641 144,200,402 RGD:13504745
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:11079192
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
G Unc119 unc-119 lipid binding chaperone JBrowse link 10 65,606,919 65,612,324 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Necab2 N-terminal EF-hand calcium binding protein 2 JBrowse link 19 52,086,325 52,112,633 RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
negative regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd13a ankyrin repeat domain 13a JBrowse link 12 47,558,587 47,588,486 RGD:1624291
G Ankrd13b ankyrin repeat domain 13B JBrowse link 10 62,674,416 62,691,949 RGD:1624291
G Ankrd13d ankyrin repeat domain 13D JBrowse link 1 219,520,316 219,532,718 RGD:1624291
G Atxn2 ataxin 2 JBrowse link 12 40,264,601 40,335,637 RGD:1624291
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554437
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:12050150
G Lrpap1 LDL receptor related protein associated protein 1 JBrowse link 14 80,911,281 80,923,290 RGD:1624291
RGD:13792537
G LRRTM1 leucine rich repeat transmembrane neuronal 1 JBrowse link 4 108,300,927 108,316,373 RGD:1624291
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 JBrowse link 18 28,012,877 28,017,925 RGD:1624291
G Mtmr2 myotubularin related protein 2 JBrowse link 8 12,283,471 12,334,014 RGD:8553482
G Sdcbp syndecan binding protein JBrowse link 5 19,471,664 19,498,499 RGD:1624291
RGD:1600115
G Wdr54 WD repeat domain 54 JBrowse link 4 114,847,722 114,871,989 RGD:1624291
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoc1 apolipoprotein C1 JBrowse link 1 80,606,638 80,609,921 RGD:1624291
G Apoc2 apolipoprotein C2 JBrowse link 1 80,589,023 80,593,991 RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
RGD:1600115
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:1600115
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:1600115
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
positive regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1600115
RGD:1624291
G Dgkd diacylglycerol kinase, delta JBrowse link 9 94,980,328 95,071,531 RGD:1624291
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:728683
G Scyl2 SCY1 like pseudokinase 2 JBrowse link 7 30,291,087 30,344,464 RGD:1624291
G Wasl WASP like actin nucleation promoting factor JBrowse link 4 51,677,722 51,726,212 RGD:8554834
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:12907555
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
positive regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahi1 Abelson helper integration site 1 JBrowse link 1 16,478,127 16,601,769 RGD:1624291
RGD:1600115
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1600115
RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:13461854
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5510008
RGD:1624291
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:1624291
RGD:1600115
G Cd63 Cd63 molecule JBrowse link 7 3,320,250 3,335,583 RGD:1600115
RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1624291
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:2311559
G Dtnbp1 dystrobrevin binding protein 1 JBrowse link 17 20,090,136 20,182,332 RGD:8553895
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:1624291
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1600115
RGD:1624291
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:1600115
RGD:1624291
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:1624291
RGD:1600115
G Pard3 par-3 family cell polarity regulator JBrowse link 19 60,017,746 60,580,628 RGD:1624291
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1624291
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:8554748
RGD:13792537
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1624291
RGD:1600115
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 JBrowse link 1 103,197,918 103,258,309 RGD:9835004
G Scyl2 SCY1 like pseudokinase 2 JBrowse link 7 30,291,087 30,344,464 RGD:1624291
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:1624291
RGD:1600115
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Synj2bp synaptojanin 2 binding protein JBrowse link 6 105,224,166 105,261,549 RGD:1624291
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 9 1,144,641 1,747,732 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
positive regulation of receptor-mediated endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:13452389
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Bicd1 BICD cargo adaptor 1 JBrowse link 4 184,018,845 184,167,628 RGD:1624291
RGD:13792537
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600115
RGD:1624291
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:1624291
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1600115
RGD:1624291
G H1f1 H1.1 linker histone, cluster member JBrowse link 17 43,614,101 43,614,844 RGD:1624291
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
G Hip1 huntingtin interacting protein 1 JBrowse link 12 24,180,795 24,315,373 RGD:1624291
RGD:13792537
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:13792537
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:13825436
RGD:13792537
RGD:1624291
G Kif3a kinesin family member 3a JBrowse link 10 38,918,705 38,953,958 RGD:1581596
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:2299909
G Ppt1 palmitoyl-protein thioesterase 1 JBrowse link 5 140,538,260 140,558,163 RGD:1624291
RGD:8553248
G Rab21 RAB21, member RAS oncogene family JBrowse link 7 58,261,985 58,286,770 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
RGD:8554276
G Sgip1 SH3GL interacting endocytic adaptor 1 JBrowse link 5 122,300,415 122,498,478 RGD:1624291
RGD:8554282
RGD:1600115
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:2314546
G Synj1 synaptojanin 1 JBrowse link 11 31,105,784 31,181,573 RGD:2312450
G Tf transferrin JBrowse link 8 111,694,570 111,721,275 RGD:1624291
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:1624291
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:1624291
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 JBrowse link 5 152,964,294 152,987,286 RGD:1624291
regulation of clathrin-dependent endocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aak1 AP2 associated kinase 1 JBrowse link 4 118,653,851 118,806,796 RGD:8553925
RGD:13792537
RGD:1624291
RGD:1600115
G Bmp2k BMP-2 inducible kinase JBrowse link 14 14,126,086 14,226,823 RGD:13792537
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 120,330,372 120,492,515 RGD:1624291
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1600115
G Prom2 prominin 2 JBrowse link 3 120,087,633 120,107,495 RGD:1624291
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 JBrowse link 5 103,479,767 103,654,507 RGD:13504745
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 JBrowse link 1 144,069,641 144,200,402 RGD:13504745
G Smap1 small ArfGAP 1 JBrowse link 9 30,068,888 30,161,753 RGD:1624291
RGD:13792537
G Snap91 synaptosome associated protein 91 JBrowse link 8 94,447,558 94,564,772 RGD:1624291
RGD:1600115
G Tnk2 tyrosine kinase, non-receptor, 2 JBrowse link 11 71,348,726 71,388,520 RGD:1624291
regulation of postsynaptic neurotransmitter receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:2313185
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:1624291
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:1624291
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:13702467
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:1600115
RGD:1624291
G Efnb2 ephrin B2 JBrowse link 16 86,631,151 86,672,050 RGD:1624291
G Gsg1l GSG1-like JBrowse link 1 197,271,704 197,482,776 RGD:1624291
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:13702182
G Hpca hippocalcin JBrowse link 5 147,295,124 147,305,757 RGD:13702412
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 JBrowse link 4 123,400,717 123,454,656 RGD:1624291
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:13702142
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:1600115
RGD:1624291
G Ophn1 oligophrenin 1 JBrowse link X 68,185,865 68,579,518 RGD:1624291
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 JBrowse link 20 7,241,248 7,286,702 RGD:13702454
RGD:13702399
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:13702248
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma JBrowse link 7 11,267,207 11,294,291 RGD:1624291
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:12050130
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:13702139
G Syne1 spectrin repeat containing nuclear envelope protein 1 JBrowse link 1
1
41,608,287
41,844,840
41,763,591
42,086,662
RGD:13209020
G Synj1 synaptojanin 1 JBrowse link 11 31,105,784 31,181,573 RGD:1624291
G Usp46 ubiquitin specific peptidase 46 JBrowse link 14 36,687,134 36,755,360 RGD:11056935
regulation of receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:8553918
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1624291
G Mkln1 muskelin 1 JBrowse link 4 58,693,384 58,817,924 RGD:13702173
G Napb NSF attachment protein beta JBrowse link 3 143,017,571 143,063,904 RGD:633462
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:633462
G Rspo1 R-spondin 1 JBrowse link 5 142,986,526 143,007,847 RGD:1624291
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 JBrowse link 5 103,479,767 103,654,507 RGD:1624291
G Synj2bp synaptojanin 2 binding protein JBrowse link 6 105,224,166 105,261,549 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      vesicle-mediated transport 1651
        endocytosis 670
          regulation of endocytosis 236
            regulation of receptor-mediated endocytosis 120
              modulation by symbiont of host receptor-mediated endocytosis + 0
              negative regulation of receptor-mediated endocytosis + 24
              positive regulation of receptor-mediated endocytosis + 61
              regulation of clathrin-dependent endocytosis + 18
              regulation of receptor internalization + 76
              regulation of receptor-mediated endocytosis involved in cholesterol transport + 4
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4905
        transport 4762
          vesicle-mediated transport 1651
            endocytosis 670
              receptor-mediated endocytosis 250
                regulation of receptor-mediated endocytosis 120
                  modulation by symbiont of host receptor-mediated endocytosis + 0
                  negative regulation of receptor-mediated endocytosis + 24
                  positive regulation of receptor-mediated endocytosis + 61
                  regulation of clathrin-dependent endocytosis + 18
                  regulation of receptor internalization + 76
                  regulation of receptor-mediated endocytosis involved in cholesterol transport + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.