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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA stabilization
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Accession:GO:0048255 term browser browse the term
Definition:Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.

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show annotations for term's descendants           Sort by:
mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:15480992) MGI PMID:15480992 NCBI chrNW_004955413:6,471,933...6,480,475
Ensembl chrNW_004955413:6,471,953...6,480,469 		JBrowse link
G Axin2 axin 2 involved_in ISO (PMID:17072303) BHF-UCL PMID:17072303 NCBI chrNW_004955478:4,952,551...4,982,223
Ensembl chrNW_004955478:4,952,488...4,982,225 		JBrowse link
G Cirbp cold inducible RNA binding protein involved_in ISO (PMID:11574538) UniProt PMID:11574538 NCBI chrNW_004955495:6,634,389...6,640,800
Ensembl chrNW_004955495:6,634,394...6,640,800 		JBrowse link
G Dicer1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (PMID:22844247) MGI PMID:22844247 NCBI chrNW_004955438:17,374,899...17,431,599
Ensembl chrNW_004955438:17,382,493...17,431,797 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO (PMID:15766563) BHF-UCL PMID:15766563 NCBI chrNW_004955422:27,638,625...27,643,261
Ensembl chrNW_004955422:27,633,827...27,642,241 		JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:24335285), (PMID:32354837) UniProt PMID:24335285 PMID:32354837 NCBI chrNW_004955455:5,612,087...5,660,543
Ensembl chrNW_004955455:5,611,093...5,660,104 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:19029303)
(PMID:14976220), (PMID:21613615)
(PMID:21613615)
(PMID:31358969)
(MGI:5922838|PMID:27609837)
(MGI:5559905|PMID:24394384)		 UniProt
MGI
CACAO		 PMID:14976220 PMID:19029303 PMID:21613615 PMID:24394384 PMID:27609837 More... MGI:5559905 MGI:5922838 NCBI chrNW_004955563:1,283,424...1,315,283
Ensembl chrNW_004955563:1,283,421...1,315,283 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO (PMID:12358785) BHF-UCL PMID:12358785 NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:17174306) UniProt PMID:17174306 NCBI chrNW_004955406:8,000,269...8,021,554
Ensembl chrNW_004955406:8,000,269...8,021,554 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:21822257) MGI PMID:21822257 NCBI chrNW_004955406:42,056,014...42,077,701
Ensembl chrNW_004955406:42,056,014...42,077,701 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO (PMID:25940091), (PMID:28673543) UniProt PMID:25940091 PMID:28673543 NCBI chrNW_004955408:9,002,443...9,080,938
Ensembl chrNW_004955408:9,002,458...9,080,938 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:11741878) MGI PMID:11741878 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Meioc meiosis specific with coiled-coil domain involved_in ISO (MGI:5770021|PMID:26742488) UniProt PMID:26742488 MGI:5770021 NCBI chrNW_004955451:17,534,644...17,547,095
Ensembl chrNW_004955451:17,534,659...17,545,584 		JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit involved_in ISO (PMID:29290617) ARUK-UCL PMID:29290617 NCBI chrNW_004955428:21,475,981...21,507,730
Ensembl chrNW_004955428:21,475,981...21,507,730 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:21073857 RGD:10040969 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694 		JBrowse link
G Noct nocturnin involved_in ISO (MGI:5308514|PMID:22073225) UniProt PMID:22073225 MGI:5308514 NCBI chrNW_004955428:4,559,027...4,580,013 JBrowse link
G Nrde2 NRDE-2, necessary for RNA interference, domain containing involved_in ISO (PMID:30842217) UniProt PMID:30842217 NCBI chrNW_004955438:12,726,206...12,780,364
Ensembl chrNW_004955438:12,726,357...12,780,379 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (MGI:7539456|PMID:32732889)
(PMID:32732889)		 RGD
UniProt		 PMID:16855020 PMID:32732889 MGI:7539456 RGD:10045995 NCBI chrNW_004955439:17,925,205...18,079,727
Ensembl chrNW_004955439:17,925,229...18,079,727 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO RGD PMID:19508861 RGD:151667451 NCBI chrNW_004955516:904,852...934,313
Ensembl chrNW_004955516:904,062...934,313 		JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in ISO (PMID:29104163) UniProt PMID:29104163 NCBI chrNW_004955483:8,705,533...8,716,772
Ensembl chrNW_004955483:8,705,213...8,716,778 		JBrowse link
G Rbm46 RNA binding motif protein 46 acts_upstream_of_or_within ISO (PMID:25397698) MGI PMID:25397698 NCBI chrNW_004955471:12,096,400...12,167,536 JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO (PMID:9009318) MGI PMID:9009318 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chrNW_004955451:4,992,634...4,996,619
Ensembl chrNW_004955451:4,992,634...4,999,029 		JBrowse link
G Taf15 TATA-box binding protein associated factor 15 acts_upstream_of_or_within ISO (PMID:27378374) MGI PMID:27378374 NCBI chrNW_004955481:10,242,839...10,274,961
Ensembl chrNW_004955481:10,252,393...10,274,860 		JBrowse link
G Tent5c terminal nucleotidyltransferase 5C involved_in ISO (PMID:28931820)
(MGI:5926094|PMID:28931820)		 UniProt PMID:28931820 MGI:5926094 NCBI chrNW_004955435:20,790,410...20,811,730
Ensembl chrNW_004955435:20,792,773...20,811,723 		JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 involved_in ISO (PMID:18794151) UniProt PMID:18794151 NCBI chrNW_004955452:14,233,155...14,282,521
Ensembl chrNW_004955452:14,233,155...14,283,886 		JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in ISO (PMID:17785852)
(PMID:21822258)		 MGI PMID:17785852 PMID:21822258 NCBI chrNW_004955411:36,328,152...36,363,614
Ensembl chrNW_004955411:36,326,926...36,363,288 		JBrowse link
G Traf5 TNF receptor associated factor 5 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chrNW_004955489:935,601...995,162
Ensembl chrNW_004955489:949,890...995,162 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:12881220 RGD:1580563 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Ybx1 Y-box binding protein 1 involved_in ISO (PMID:31358969) UniProt PMID:31358969 NCBI chrNW_004955537:2,234,052...2,254,528
Ensembl chrNW_004955537:2,234,054...2,251,708 		JBrowse link
G Ybx2 Y-box binding protein 2 acts_upstream_of_or_within ISO (PMID:17035640) MGI PMID:17035640 NCBI chrNW_004955467:9,624,506...9,629,904
Ensembl chrNW_004955467:9,624,019...9,629,904 		JBrowse link
3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angel2 angel homolog 2 involved_in ISO (PMID:22547059) HGNC PMID:22547059 NCBI chrNW_004955406:4,589,849...4,606,380
Ensembl chrNW_004955406:4,589,849...4,606,380 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in ISO (PMID:14517288), (PMID:26489465), (PMID:29180010)
(MGI:6105829|PMID:27616329)
(PMID:19029303)		 UniProt PMID:14517288 PMID:19029303 PMID:26489465 PMID:27616329 PMID:29180010 MGI:6105829 NCBI chrNW_004955563:1,283,424...1,315,283
Ensembl chrNW_004955563:1,283,421...1,315,283 		JBrowse link
G Elavl4 ELAV like RNA binding protein 4 involved_in ISO (PMID:12034726) UniProt PMID:12034726 NCBI chrNW_004955464:8,699,142...8,847,289
Ensembl chrNW_004955464:8,699,088...8,788,878 		JBrowse link
G Hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 involved_in ISO (MGI:5306322|PMID:12456657) UniProt PMID:12456657 MGI:5306322 NCBI chrNW_004955408:32,718,736...32,719,409 JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:16010978) UniProt PMID:16010978 NCBI chrNW_004955550:1,949,975...2,002,297
Ensembl chrNW_004955550:1,949,975...2,002,297 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (PMID:14517288), (PMID:15014438), (PMID:20932473) UniProt PMID:14517288 PMID:15014438 PMID:20932473 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:15294994) BHF-UCL PMID:15294994 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 ISO RGD PMID:11696543 RGD:10045987 NCBI chrNW_004955495:6,990,565...7,002,492
Ensembl chrNW_004955495:6,987,182...7,002,492 		JBrowse link
G Rbm10 RNA binding motif protein 10 acts_upstream_of_or_within ISO (PMID:19508861) MGI PMID:19508861 NCBI chrNW_004955516:904,852...934,313
Ensembl chrNW_004955516:904,062...934,313 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chrNW_004955445:2,036,314...2,050,882
Ensembl chrNW_004955445:2,036,124...2,052,139 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:34160127)
(MGI:6859910|PMID:29844590)		 UniProt PMID:29844590 PMID:34160127 MGI:6859910 NCBI chrNW_004955443:6,940,523...7,100,130
Ensembl chrNW_004955443:6,940,523...7,100,130 		JBrowse link
G Tardbp TAR DNA binding protein involved_in ISO (PMID:17481916) BHF-UCL PMID:17481916 NCBI chrNW_004955486:2,656,121...2,674,808
Ensembl chrNW_004955486:2,656,121...2,674,807 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:15294994) BHF-UCL PMID:15294994 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in ISO (PMID:15014438) UniProt PMID:15014438 NCBI chrNW_004955468:152,744...155,140
Ensembl chrNW_004955468:152,744...155,140 		JBrowse link
CRD-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csde1 cold shock domain containing E1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004955435:18,009,228...18,050,329
Ensembl chrNW_004955435:18,008,352...18,050,329 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004955406:21,697,813...21,743,551
Ensembl chrNW_004955406:21,697,813...21,745,011 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004955433:6,452,931...6,470,209
Ensembl chrNW_004955433:6,454,454...6,469,904 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004955406:8,000,269...8,021,554
Ensembl chrNW_004955406:8,000,269...8,021,554 		JBrowse link
G Igf2bp1 insulin like growth factor 2 mRNA binding protein 1 involved_in ISO (PMID:19029303), (PMID:29476152) UniProt PMID:19029303 PMID:29476152 NCBI chrNW_004955451:12,312,715...12,348,663
Ensembl chrNW_004955451:12,312,715...12,348,663 		JBrowse link
G Igf2bp2 insulin like growth factor 2 mRNA binding protein 2 involved_in ISO (PMID:29476152) UniProt PMID:29476152 NCBI chrNW_004955420:21,818,970...21,957,295
Ensembl chrNW_004955420:21,818,972...21,958,440 		JBrowse link
G Igf2bp3 insulin like growth factor 2 mRNA binding protein 3 involved_in ISO (PMID:29476152) UniProt PMID:29476152 NCBI chrNW_004955410:25,605,323...25,734,845
Ensembl chrNW_004955410:25,605,323...25,731,169 		JBrowse link
G Pabpc1 poly(A) binding protein cytoplasmic 1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004955417:15,872,906...15,885,246
Ensembl chrNW_004955417:15,868,934...15,885,247 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 involved_in ISO (PMID:11051545) ComplexPortal PMID:11051545 NCBI chrNW_004955446:18,801,971...18,830,816
Ensembl chrNW_004955446:18,801,578...18,831,963 		JBrowse link
G Syncrip synaptotagmin binding cytoplasmic RNA interacting protein involved_in ISO (PMID:19029303)
(PMID:11051545), (PMID:19029303)		 UniProt
ComplexPortal		 PMID:11051545 PMID:19029303 NCBI chrNW_004955411:13,068,078...13,096,936
Ensembl chrNW_004955411:13,066,789...13,096,938 		JBrowse link
G Ybx1 Y-box binding protein 1 involved_in ISO (PMID:19029303) UniProt PMID:19029303 NCBI chrNW_004955537:2,234,052...2,254,528
Ensembl chrNW_004955537:2,234,054...2,251,708 		JBrowse link
negative regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl16 methyltransferase 16, RNA N6-adenosine involved_in ISO (PMID:28525753) UniProt PMID:28525753 NCBI chrNW_004955481:762,030...836,299
Ensembl chrNW_004955481:762,024...836,067 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (MGI:6384430|PMID:31868295) UniProt PMID:31868295 MGI:6384430 NCBI chrNW_004955439:17,925,205...18,079,727
Ensembl chrNW_004955439:17,925,229...18,079,727 		JBrowse link
positive regulation of 3'-UTR-mediated mRNA stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elavl4 ELAV like RNA binding protein 4 involved_in ISO (PMID:18218628) UniProt PMID:18218628 NCBI chrNW_004955464:8,699,142...8,847,289
Ensembl chrNW_004955464:8,699,088...8,788,878 		JBrowse link
G Larp4b La ribonucleoprotein 4B involved_in ISO (PMID:26001795) FlyBase PMID:26001795 NCBI chrNW_004955492:113,900...197,753
Ensembl chrNW_004955492:138,374...193,145 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (MGI:5903342|PMID:28188285) UniProt PMID:28188285 MGI:5903342 NCBI chrNW_004955439:17,925,205...18,079,727
Ensembl chrNW_004955439:17,925,229...18,079,727 		JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in ISO (PMID:24356969) UniProt PMID:24356969 NCBI chrNW_004955483:8,705,533...8,716,772
Ensembl chrNW_004955483:8,705,213...8,716,778 		JBrowse link
G Tent4a terminal nucleotidyltransferase 4A involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004955504:4,443,051...4,476,373
Ensembl chrNW_004955504:4,443,051...4,476,520 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:30026317) UniProt PMID:30026317 NCBI chrNW_004955433:8,288,432...8,347,347
Ensembl chrNW_004955433:8,288,432...8,347,347 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological quality 2623
        regulation of RNA stability 143
          regulation of mRNA stability 132
            mRNA stabilization 56
              3'-UTR-mediated mRNA stabilization + 20
              CRD-mediated mRNA stabilization 11
Path 2
Term Annotations click to browse term
  biological_process 12346
    biological regulation 8880
      regulation of biological process 8618
        regulation of metabolic process 4808
          regulation of biosynthetic process 3812
            regulation of cellular biosynthetic process 3728
              regulation of macromolecule biosynthetic process 3635
                regulation of gene expression 3524
                  negative regulation of gene expression 965
                    mRNA catabolic process 192
                      regulation of mRNA catabolic process 148
                        regulation of mRNA stability 132
                          mRNA stabilization 56
                            3'-UTR-mediated mRNA stabilization + 20
                            CRD-mediated mRNA stabilization 11
paths to the root