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Term:negative regulation of melanin biosynthetic process
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Accession:GO:0048022 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: down regulation of melanin biosynthetic process;   downregulation of melanin biosynthetic process;   negative regulation of melanin anabolism;   negative regulation of melanin biosynthesis;   negative regulation of melanin formation;   negative regulation of melanin synthesis
 narrow_synonym: inhibition of melanin biosynthetic process

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negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (MGI:5912387|PMID:29025994) CACAO PMID:29025994 MGI:5912387 NCBI chrNW_004955495:5,505,528...5,516,330
Ensembl chrNW_004955495:5,506,154...5,516,142
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) UniProt PMID:31097585 NCBI chrNW_004955406:10,450,810...10,493,958
Ensembl chrNW_004955406:10,450,768...10,493,958
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (MGI:5499726|PMID:16272156) UniProt PMID:16272156 MGI:5499726 NCBI chrNW_004955471:12,670,837...12,838,910
Ensembl chrNW_004955471:12,670,764...12,815,430
JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) MGI PMID:18166528 MGI:3775882 NCBI chrNW_004955409:5,747,624...5,768,122
Ensembl chrNW_004955409:5,747,624...5,768,122
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5619434|PMID:23569434) CACAO PMID:23569434 MGI:5619434 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11978
    metabolic process 7562
      biosynthetic process 3903
        negative regulation of biosynthetic process 1334
          negative regulation of cellular biosynthetic process 1293
            negative regulation of melanin biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 11978
    cellular process 11211
      cellular metabolic process 6947
        cellular aromatic compound metabolic process 3751
          phenol-containing compound metabolic process 105
            phenol-containing compound biosynthetic process 43
              melanin biosynthetic process 20
                regulation of melanin biosynthetic process 14
                  negative regulation of melanin biosynthetic process 5
paths to the root