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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of melanin biosynthetic process
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Accession:GO:0048021 term browser browse the term
Definition:Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: regulation of melanin anabolism;   regulation of melanin biosynthesis;   regulation of melanin formation;   regulation of melanin synthesis



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regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (PMID:22649030) RGD PMID:22649030 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:33208952)
(MGI:6492453|PMID:33208952)
(PMID:31117290)
RGD PMID:31117290 PMID:33208952 MGI:6492453 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988
JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (MGI:3588610|PMID:16037214) RGD PMID:16037214 MGI:3588610 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (MGI:5912387|PMID:29025994) RGD PMID:29025994 MGI:5912387 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) RGD PMID:31097585 NCBI chr13:87,589,330...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5499726|PMID:16272156)
UniProt
RGD
PMID:16272156 GO_REF:0000024 MGI:5499726 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) RGD PMID:18166528 MGI:3775882 NCBI chr 3:112,319,305...112,339,231
Ensembl chr 3:112,319,308...112,339,231
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5619434|PMID:23569434) RGD PMID:23569434 MGI:5619434 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) RGD PMID:21291857 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Asip agouti signaling protein involved_in IBA
ISO
PMID:21873635
UniProtKB:P07147|UniProtKB:Q60696 (MGI:5294257|PMID:21949658)
RGD PMID:21949658 PMID:21873635 MGI:5294257, RGD:13792537 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171
JBrowse link
G Atp7a ATPase copper transporting alpha involved_in ISS
ISO
GO_REF:0000024
(PMID:11092760)
UniProt
RGD
PMID:11092760 GO_REF:0000024 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21291857)
UniProt
RGD
PMID:21291857 GO_REF:0000024 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:28842328) RGD PMID:28842328 NCBI chr13:87,589,330...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Pmel premelanosome protein involved_in ISO (MGI:5294257|PMID:21949658) RGD PMID:21949658 MGI:5294257 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746
JBrowse link
G Rab38 RAB38, member RAS oncogene family IMP RGD PMID:17043139 RGD:152025192 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in ISO (PMID:21996312)
UniProtKB:Q03288|UniProtKB:Q60696 (MGI:5294257|PMID:21949658)
RGD PMID:21949658 PMID:21996312 MGI:5294257 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      biosynthetic process 5893
        regulation of biosynthetic process 4036
          regulation of cellular biosynthetic process 3955
            regulation of melanin biosynthetic process 15
              negative regulation of melanin biosynthetic process 5
              positive regulation of melanin biosynthetic process 9
Path 2
Term Annotations click to browse term
  biological_process 18877
    cellular process 17586
      cellular metabolic process 9831
        cellular aromatic compound metabolic process 5651
          phenol-containing compound metabolic process 129
            melanin metabolic process 25
              melanin biosynthetic process 23
                regulation of melanin biosynthetic process 15
                  negative regulation of melanin biosynthetic process 5
                  positive regulation of melanin biosynthetic process 9
paths to the root