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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of melanin biosynthetic process
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Accession:GO:0048021 term browser browse the term
Definition:Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: regulation of melanin anabolism;   regulation of melanin biosynthesis;   regulation of melanin formation;   regulation of melanin synthesis


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regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter involved_in ISO (PMID:22649030) UniProt PMID:22649030 NCBI chr 9:47,474,488...47,490,951
Ensembl chr 9:47,473,901...47,490,252
JBrowse link
G MFSD12 major facilitator superfamily domain containing 12 involved_in IMP (PMID:31117290) UniProt PMID:31117290 NCBI chr20:55,855,102...55,863,606
Ensembl chr20:55,858,687...55,862,181
JBrowse link
G SLC7A11 solute carrier family 7 member 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3588610|PMID:16037214) Ensembl
MGI
PMID:16037214 GO_REF:0000107 MGI:3588610 NCBI chr19:4,289,792...4,379,060
Ensembl chr19:4,289,850...4,389,048
JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFSD12 major facilitator superfamily domain containing 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,855,102...55,863,606
Ensembl chr20:55,858,687...55,862,181
JBrowse link
G OPN3 opsin 3 involved_in ISO (PMID:31097585) UniProt PMID:31097585 NCBI chr 7:32,995,047...33,040,873
Ensembl chr 7:32,996,938...33,040,876
JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:56,133,094...56,353,609
Ensembl chr15:56,174,578...56,352,569
JBrowse link
G SLC24A5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) MGI PMID:18166528 MGI:3775882 NCBI chr30:14,372,019...14,400,262
Ensembl chr30:14,371,778...14,400,152
JBrowse link
G WNT5A Wnt family member 5A involved_in ISO (MGI:5619434|PMID:23569434) CACAO PMID:23569434 MGI:5619434 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792
JBrowse link
G ASIP agouti signaling protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:23,338,757...23,393,913
Ensembl chr24:23,354,888...23,393,896
JBrowse link
G ATP7A ATPase copper transporting alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869
JBrowse link
G CDH3 cadherin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:80,864,859...80,912,136
Ensembl chr 5:80,863,661...80,913,019
JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in ISO (PMID:21291857) UniProt PMID:21291857 NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191
JBrowse link
G OPN3 opsin 3 involved_in ISO (PMID:28842328) UniProt PMID:28842328 NCBI chr 7:32,995,047...33,040,873
Ensembl chr 7:32,996,938...33,040,876
JBrowse link
G PMEL premelanosome protein involved_in ISO (MGI:5294257|PMID:21949658) CACAO PMID:21949658 MGI:5294257 NCBI chr10:292,595...327,618
Ensembl chr10:292,597...300,098
JBrowse link
G TYRP1 tyrosinase related protein 1 involved_in ISO (PMID:21996312)
(MGI:5294257|PMID:21949658)
CACAO PMID:21949658 PMID:21996312 MGI:5294257 NCBI chr11:33,317,084...33,336,029
Ensembl chr11:33,317,121...33,335,498
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      biosynthetic process 4553
        regulation of biosynthetic process 3299
          regulation of cellular biosynthetic process 3222
            regulation of melanin biosynthetic process 14
              negative regulation of melanin biosynthetic process 5
              positive regulation of melanin biosynthetic process 8
Path 2
Term Annotations click to browse term
  biological_process 13863
    cellular process 13104
      cellular metabolic process 8165
        cellular aromatic compound metabolic process 4383
          phenol-containing compound metabolic process 118
            melanin metabolic process 23
              melanin biosynthetic process 21
                regulation of melanin biosynthetic process 14
                  negative regulation of melanin biosynthetic process 5
                  positive regulation of melanin biosynthetic process 8
paths to the root