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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of melanin biosynthetic process
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Accession:GO:0048021 term browser browse the term
Definition:Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: regulation of melanin anabolism;   regulation of melanin biosynthesis;   regulation of melanin formation;   regulation of melanin synthesis


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regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in ISO (PMID:22649030) RGD PMID:22649030 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:33208952)
(MGI:6492453|PMID:33208952)
(PMID:31117290)		 RGD PMID:31117290 PMID:33208952 MGI:6492453 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (MGI:3588610|PMID:16037214) RGD PMID:16037214 MGI:3588610 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (MGI:5912387|PMID:29025994) RGD PMID:29025994 MGI:5912387 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) RGD PMID:31097585 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5499726|PMID:16272156)		 UniProt
RGD		 PMID:16272156 GO_REF:0000024 MGI:5499726 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) RGD PMID:18166528 MGI:3775882 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (MGI:5619434|PMID:23569434)
GO_REF:0000107		 RGD
Ensembl		 PMID:23569434 GO_REF:0000107 MGI:5619434 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) RGD PMID:21291857 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Asip agouti signaling protein involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
UniProtKB:P07147|UniProtKB:Q60696 (MGI:5294257|PMID:21949658)		 Ensembl
RGD		 PMID:21949658 PMID:21873635 GO_REF:0000107 MGI:5294257, RGD:13792537 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Atp7a ATPase copper transporting alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:11092760)		 UniProt
RGD		 PMID:11092760 GO_REF:0000024 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21291857)		 UniProt
Ensembl
RGD		 PMID:21291857 GO_REF:0000024 GO_REF:0000107 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:28842328) RGD PMID:28842328 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Pmel premelanosome protein involved_in ISO (MGI:5294257|PMID:21949658) RGD PMID:21949658 MGI:5294257 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Rab38 RAB38, member RAS oncogene family IMP RGD PMID:17043139 RGD:152025192 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 involved_in ISO (PMID:21996312)
UniProtKB:Q03288|UniProtKB:Q60696 (MGI:5294257|PMID:21949658)		 RGD PMID:21949658 PMID:21996312 MGI:5294257 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      biosynthetic process 8083
        regulation of biosynthetic process 5263
          regulation of cellular biosynthetic process 5218
            regulation of melanin biosynthetic process 15
              negative regulation of melanin biosynthetic process 5
              positive regulation of melanin biosynthetic process 9
Path 2
Term Annotations click to browse term
  biological_process 19574
    cellular process 18252
      cellular metabolic process 10142
        cellular aromatic compound metabolic process 5701
          phenol-containing compound metabolic process 132
            melanin metabolic process 26
              melanin biosynthetic process 24
                regulation of melanin biosynthetic process 15
                  negative regulation of melanin biosynthetic process 5
                  positive regulation of melanin biosynthetic process 9
paths to the root