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ONTOLOGY REPORT - ANNOTATIONS

Term:ephrin receptor signaling pathway
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Accession:GO:0048013 term browser browse the term
Definition:The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: Eph receptor signaling pathway;   Eph receptor signalling pathway
 xref: Reactome:R-HSA-2682334 "EPH-Ephrin signaling"


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ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708 		JBrowse link
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:30,812,925...30,995,369
Ensembl chr 7:30,812,920...30,995,360 		JBrowse link
G ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:84,080,505...85,148,742
Ensembl chr 5:84,080,669...85,148,976 		JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,456,063...42,494,494
Ensembl chr12:42,493,392...42,494,413 		JBrowse link
G CHN1 chimerin 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:80,731,243...80,927,746
Ensembl chr15:80,730,716...80,927,746 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,656,805...47,685,641
Ensembl chr12:47,657,865...47,685,908 		JBrowse link
G DIAPH1 diaphanous related formin 1 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chr 2:143,158,691...143,271,110
Ensembl chr 2:143,158,585...143,271,147 		JBrowse link
G DIAPH2 diaphanous related formin 2 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chr  X:78,602,385...79,520,441
Ensembl chr  X:78,602,390...79,520,428 		JBrowse link
G EFNA1 ephrin A1 involved_in
acts_upstream_of_or_within 		ISS
IEA
IBA 		UniProt
Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:94,666,457...94,673,442
Ensembl chr 4:94,666,460...94,674,071 		JBrowse link
G EFNA2 ephrin A2 involved_in IEA
IBA 		InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:77,165,187...77,179,936
Ensembl chr 2:77,165,193...77,179,246 		JBrowse link
G EFNA3 ephrin A3 involved_in IEA
IBA 		InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:94,709,941...94,719,350
Ensembl chr 4:94,710,647...94,719,248 		JBrowse link
G EFNA4 ephrin A4 involved_in IEA
IBA 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:94,730,790...94,735,578
Ensembl chr 4:94,730,792...94,735,559 		JBrowse link
G EFNA5 ephrin A5 involved_in IEA
IBA 		InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:112,533,124...112,821,293
Ensembl chr 2:112,534,949...112,815,827 		JBrowse link
G EFNB1 ephrin B1 involved_in IEA
IBA 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:54,947,339...54,961,403
Ensembl chr  X:54,948,342...54,973,629 		JBrowse link
G EFNB2 ephrin B2 involved_in IEA
IBA 		InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr11:74,188,337...74,232,768
Ensembl chr11:74,186,640...74,233,354 		JBrowse link
G EFNB3 ephrin B3 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:52,970,398...52,976,260
Ensembl chr12:52,970,285...52,976,257 		JBrowse link
G EPHA1 EPH receptor A1 involved_in IEA GOC GO_REF:0000108 NCBI chr18:6,843,305...6,860,976
Ensembl chr18:6,843,299...6,860,989 		JBrowse link
G EPHA10 EPH receptor A10 involved_in IEA
IBA 		GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 6:93,764,732...93,804,069
Ensembl chr 6:93,765,128...93,803,894 		JBrowse link
G EPHA2 EPH receptor A2 involved_in
acts_upstream_of_or_within 		IEA GOC
Ensembl		 GO_REF:0000107 GO_REF:0000108 NCBI chr 6:75,251,465...75,279,364
Ensembl chr 6:75,251,467...75,279,314 		JBrowse link
G EPHA3 EPH receptor A3 involved_in IEA
IBA 		Ensembl
GOC
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr13:166,592,492...166,942,791
Ensembl chr13:166,592,493...166,942,767 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IBA
IEA 		GO_Central
Ensembl
GOC		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126 		JBrowse link
G EPHA5 EPH receptor A5 involved_in IBA
IEA 		GO_Central
GOC		 GO_REF:0000033 GO_REF:0000108 NCBI chr 8:63,285,006...63,604,734
Ensembl chr 8:63,287,711...63,604,734 		JBrowse link
G EPHA6 EPH receptor A6 involved_in IBA
IEA 		GO_Central
GOC		 GO_REF:0000033 GO_REF:0000108 NCBI chr13:162,568,835...163,445,722
Ensembl chr13:162,569,479...163,443,646 		JBrowse link
G EPHA7 EPH receptor A7 involved_in IEA
IBA 		Ensembl
GOC
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr 1:60,771,567...60,944,092
Ensembl chr 1:60,771,572...60,944,038 		JBrowse link
G EPHA8 EPH receptor A8 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 6:80,516,967...80,548,955
Ensembl chr 6:80,516,967...80,550,588 		JBrowse link
G EPHB1 EPH receptor B1 involved_in
acts_upstream_of_or_within 		IEA
IBA 		GOC
Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr13:75,904,678...76,351,540
Ensembl chr13:75,905,676...76,345,534 		JBrowse link
G EPHB2 EPH receptor B2 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
GOC
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr 6:80,649,098...80,849,979
Ensembl chr 6:80,650,740...80,843,567 		JBrowse link
G EPHB3 EPH receptor B3 involved_in IEA
IBA 		Ensembl
GOC
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr13:122,467,561...122,488,296
Ensembl chr13:122,467,588...122,488,292 		JBrowse link
G EPHB4 EPH receptor B4 involved_in IEA
IBA 		Ensembl
GO_Central
GOC		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr 3:8,671,052...8,689,778
Ensembl chr 3:8,668,859...8,689,783 		JBrowse link
G EPHB6 EPH receptor B6 involved_in IEA
IBA 		GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr18:7,346,793...7,419,859
Ensembl chr18:7,346,565...7,389,504 		JBrowse link
G GIT1 GIT ArfGAP 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:45,768,172...45,783,652
Ensembl chr12:45,768,176...45,783,658 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,793,492...75,903,496 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,945,468 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,991...49,198,664 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:133,332,715...133,460,161
Ensembl chr15:133,332,718...133,460,166 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:10655584) UniProt PMID:10655584 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,169...39,292,003 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:94,789,794...95,168,728
Ensembl chr 7:95,022,924...95,167,107 		JBrowse link
G SS18 SS18 subunit of BAF chromatin remodeling complex acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:110,711,438...110,789,805
Ensembl chr 6:110,710,569...110,790,379 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 acts_upstream_of_or_within ISO (PMID:14988728) MGI PMID:14988728 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
positive regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr 7:30,812,925...30,995,369
Ensembl chr 7:30,812,920...30,995,360 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    cellular process 18486
      signal transduction 7030
        cell surface receptor signaling pathway 2811
          enzyme-linked receptor protein signaling pathway 1050
            cell surface receptor protein tyrosine kinase signaling pathway 671
              ephrin receptor signaling pathway 42
                negative regulation of ephrin receptor signaling pathway 0
                positive regulation of ephrin receptor signaling pathway 1
                regulation of ephrin receptor signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 18944
    biological regulation 13005
      regulation of biological process 12624
        signaling 7571
          signal transduction 7030
            cell surface receptor signaling pathway 2811
              enzyme-linked receptor protein signaling pathway 1050
                cell surface receptor protein tyrosine kinase signaling pathway 671
                  ephrin receptor signaling pathway 42
                    negative regulation of ephrin receptor signaling pathway 0
                    positive regulation of ephrin receptor signaling pathway 1
                    regulation of ephrin receptor signaling pathway + 2
paths to the root