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ONTOLOGY REPORT - ANNOTATIONS

Term:ephrin receptor signaling pathway
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Accession:GO:0048013 term browser browse the term
Definition:The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: Eph receptor signaling pathway;   Eph receptor signalling pathway
 xref: Reactome:R-HSA-2682334 "EPH-Ephrin signaling"

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ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734 		JBrowse link
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:37,036,665...37,229,906
Ensembl chr17:37,036,066...37,155,596 		JBrowse link
G ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr11:94,360,356...95,286,373 JBrowse link
G CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:26,044,751...26,048,920
Ensembl chr16:26,045,061...26,049,101 		JBrowse link
G CHN1 chimerin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:60,334,829...60,540,309
Ensembl chr10:60,331,214...60,488,785 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,102,485...1,135,225
Ensembl chr16:1,102,348...1,135,166 		JBrowse link
G DIAPH1 diaphanous related formin 1 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chr23:44,139,495...44,244,505
Ensembl chr23:44,139,360...44,244,490 		JBrowse link
G DIAPH2 diaphanous related formin 2 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chr  X:85,130,928...86,035,944 JBrowse link
G EFNA1 ephrin A1 involved_in
acts_upstream_of_or_within 		IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:8,695,446...8,702,556
Ensembl chr20:8,696,241...8,702,379 		JBrowse link
G EFNA2 ephrin A2 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:1,054,382...1,069,544
Ensembl chr 6:1,054,483...1,068,232 		JBrowse link
G EFNA3 ephrin A3 involved_in IEA Ensembl
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:8,742,383...8,751,275 JBrowse link
G EFNA4 ephrin A4 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr20:8,758,126...8,767,750
Ensembl chr20:8,761,883...8,766,830 		JBrowse link
G EFNA5 ephrin A5 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:10,823,243...11,115,175
Ensembl chr23:10,823,261...10,873,666 		JBrowse link
G EFNB1 ephrin B1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr  X:58,668,572...58,681,583
Ensembl chr  X:58,668,581...58,681,855 		JBrowse link
G EFNB2 ephrin B2 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:84,904,421...84,949,292
Ensembl chr 3:84,904,435...84,949,465 		JBrowse link
G EFNB3 ephrin B3 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:7,087,116...7,093,457
Ensembl chr16:7,087,584...7,093,621 		JBrowse link
G EPHA1 EPH receptor A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:112,276,941...112,294,505
Ensembl chr21:112,277,427...112,294,424 		JBrowse link
G EPHA10 EPH receptor A10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:95,094,971...95,145,264
Ensembl chr20:95,098,283...95,142,863 		JBrowse link
G EPHA2 EPH receptor A2 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:116,147,077...116,178,647
Ensembl chr20:116,147,040...116,178,644 		JBrowse link
G EPHA3 EPH receptor A3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:87,480,220...87,840,628
Ensembl chr22:87,480,126...87,838,512 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:107,344,442...107,501,375
Ensembl chr10:107,352,530...107,499,788 		JBrowse link
G EPHA5 EPH receptor A5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:3,219,396...3,564,416
Ensembl chr 7:3,219,449...3,559,854 		JBrowse link
G EPHA7 EPH receptor A7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:18,097,051...18,283,664
Ensembl chr13:18,099,005...18,281,415 		JBrowse link
G EPHA8 EPH receptor A8 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:110,061,871...110,095,354
Ensembl chr20:110,063,727...110,101,072 		JBrowse link
G EPHB1 EPH receptor B1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:55,144,178...55,592,252
Ensembl chr15:55,143,630...55,589,862 		JBrowse link
G EPHB2 EPH receptor B2 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777 		JBrowse link
G EPHB3 EPH receptor B3 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:4,831,980...4,852,586
Ensembl chr15:4,832,750...4,852,152 		JBrowse link
G EPHB4 EPH receptor B4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:12,389,884...12,416,746
Ensembl chr28:12,389,942...12,416,920 		JBrowse link
G EPHB6 EPH receptor B6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:111,742,236...111,750,349
Ensembl chr21:111,742,268...111,752,179 		JBrowse link
G GIT1 GIT ArfGAP 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:23,313,629...23,329,665
Ensembl chr16:23,315,439...23,329,469 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:53,501,152...53,595,500
Ensembl chr15:53,500,623...53,523,576 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:9,412,677...9,515,565
Ensembl chr14:9,437,301...9,515,561 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:118,911,019...118,959,259 JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:10655584) UniProt PMID:10655584 NCBI chr 8:134,897,511...135,246,300 JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:48,542,976...48,965,378
Ensembl chr24:48,636,323...48,965,371 		JBrowse link
G SS18 SS18 subunit of BAF chromatin remodeling complex acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:54,477,339...54,548,920
Ensembl chr18:54,477,959...54,546,814 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 acts_upstream_of_or_within ISO (PMID:14988728) MGI PMID:14988728 NCBI chr 2:60,573,187...61,015,599
Ensembl chr 2:60,865,819...61,017,191 		JBrowse link
positive regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:17336907) BHF-UCL PMID:17336907 NCBI chr27:23,911,084...24,023,856 JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 Ensembl chr27:23,910,533...23,921,725 JBrowse link
regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr17:37,036,665...37,229,906
Ensembl chr17:37,036,066...37,155,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      signal transduction 5673
        cell surface receptor signaling pathway 2811
          enzyme-linked receptor protein signaling pathway 1008
            cell surface receptor protein tyrosine kinase signaling pathway 653
              ephrin receptor signaling pathway 41
                negative regulation of ephrin receptor signaling pathway 0
                positive regulation of ephrin receptor signaling pathway 2
                regulation of ephrin receptor signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 19706
    biological regulation 12159
      regulation of biological process 11759
        signaling 6206
          signal transduction 5673
            cell surface receptor signaling pathway 2811
              enzyme-linked receptor protein signaling pathway 1008
                cell surface receptor protein tyrosine kinase signaling pathway 653
                  ephrin receptor signaling pathway 41
                    negative regulation of ephrin receptor signaling pathway 0
                    positive regulation of ephrin receptor signaling pathway 2
                    regulation of ephrin receptor signaling pathway + 3
paths to the root