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ONTOLOGY REPORT - ANNOTATIONS

Term:ephrin receptor signaling pathway
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Accession:GO:0048013 term browser browse the term
Definition:The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: Eph receptor signaling pathway;   Eph receptor signalling pathway
 xref: Reactome:R-HSA-2682334 "EPH-Ephrin signaling"

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ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:24658113) ARUK-UCL PMID:24658113 NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239 		JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A involved_in ISO (PMID:17875921) UniProt PMID:17875921 NCBI chrNW_004955437:2,916,598...3,070,771
Ensembl chrNW_004955437:2,916,598...3,070,771 		JBrowse link
G Cdk5r1 cyclin dependent kinase 5 regulatory subunit 1 involved_in ISO (PMID:17143272) UniProt PMID:17143272 NCBI chrNW_004955481:7,408,089...7,411,813
Ensembl chrNW_004955481:7,408,205...7,409,128 		JBrowse link
G Chn1 chimerin 1 involved_in ISO (PMID:17785183) UniProt PMID:17785183 NCBI chrNW_004955449:574,407...635,566 JBrowse link
G Crk CRK proto-oncogene, adaptor protein involved_in ISO (PMID:11870224) UniProt PMID:11870224 NCBI chrNW_004955481:1,705,595...1,748,363
Ensembl chrNW_004955481:1,705,520...1,734,859 		JBrowse link
G Diaph1 diaphanous related formin 1 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chrNW_004955415:12,156,152...12,272,961
Ensembl chrNW_004955415:12,156,152...12,272,961 		JBrowse link
G Diaph2 diaphanous related formin 2 acts_upstream_of_or_within ISO (PMID:23890216) MGI PMID:23890216 NCBI chrNW_004955503:2,324,934...3,132,466
Ensembl chrNW_004955503:2,325,103...2,835,656 		JBrowse link
G Efna1 ephrin A1 involved_in
acts_upstream_of_or_within 		ISO (PMID:10655584)
(PMID:24217950)
(PMID:17143272)
(PMID:14988728), (PMID:15145949) 		UniProt
ARUK-UCL
MGI		 PMID:10655584 PMID:14988728 PMID:15145949 PMID:17143272 PMID:24217950 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460 		JBrowse link
G Efna2 ephrin A2 involved_in ISO (PMID:9053851) UniProt PMID:9053851 NCBI chrNW_004955495:6,614,828...6,627,287
Ensembl chrNW_004955495:6,614,791...6,627,287 		JBrowse link
G Efna3 ephrin A3 involved_in ISO (PMID:24217950)
(PMID:9053851) 		ARUK-UCL
UniProt		 PMID:9053851 PMID:24217950 NCBI chrNW_004955545:1,570,351...1,578,610
Ensembl chrNW_004955545:1,570,339...1,577,639 		JBrowse link
G Efna5 ephrin A5 involved_in ISO (PMID:11870224)
(PMID:17448994), (PMID:9053851) 		UniProt PMID:9053851 PMID:11870224 PMID:17448994 NCBI chrNW_004955418:6,919,270...7,188,561
Ensembl chrNW_004955418:6,920,919...7,185,478 		JBrowse link
G Efnb2 ephrin B2 involved_in ISO (PMID:12734395) UniProt PMID:12734395 NCBI chrNW_004955404:5,000,906...5,030,068
Ensembl chrNW_004955404:5,000,906...5,030,126 		JBrowse link
G Efnb3 ephrin B3 acts_upstream_of_or_within ISO (PMID:8808709) MGI PMID:8808709 NCBI chrNW_004955467:9,217,796...9,225,223
Ensembl chrNW_004955467:9,217,796...9,224,940 		JBrowse link
G Epha2 EPH receptor A2 involved_in
acts_upstream_of_or_within 		ISO (PMID:10655584), (PMID:20861311)
(PMID:18948590)
(PMID:14988728) 		UniProt
MGI		 PMID:10655584 PMID:14988728 PMID:18948590 PMID:20861311 NCBI chrNW_004955527:2,120,447...2,151,932
Ensembl chrNW_004955527:2,120,266...2,152,781 		JBrowse link
G Epha3 EPH receptor A3 involved_in ISO (PMID:11870224)
(PMID:21135139) 		UniProt PMID:11870224 PMID:21135139 NCBI chrNW_004955407:4,135,671...4,500,900
Ensembl chrNW_004955407:4,138,362...4,500,688 		JBrowse link
G Epha4 EPH receptor A4 involved_in ISO (PMID:24217950)
(PMID:24658113) 		ARUK-UCL PMID:24217950 PMID:24658113 RGD:12911004 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199 		JBrowse link
G Epha5 EPH receptor A5 involved_in ISO PMID:20824214
(PMID:17448994) 		UniProt PMID:17448994 PMID:20824214 RGD:8554330 NCBI chrNW_004955447:7,066,111...7,382,046
Ensembl chrNW_004955447:7,066,111...7,382,046 		JBrowse link
G Epha7 EPH receptor A7 involved_in ISO (PMID:17726105)
(PMID:11089974) 		UniProt PMID:11089974 PMID:17726105 NCBI chrNW_004955411:19,652,146...19,815,418
Ensembl chrNW_004955411:19,650,515...19,815,512 		JBrowse link
G Epha8 EPH receptor A8 involved_in ISO (PMID:11416136), (PMID:17875921), (PMID:9053851) UniProt PMID:9053851 PMID:11416136 PMID:17875921 NCBI chrNW_004955452:2,702,277...2,729,161
Ensembl chrNW_004955452:2,701,803...2,729,277 		JBrowse link
G Ephb1 EPH receptor B1 involved_in
acts_upstream_of_or_within 		ISO (PMID:12925710), (PMID:18034775)
(PMID:17310244) 		UniProt
MGI		 PMID:12925710 PMID:17310244 PMID:18034775 NCBI chrNW_004955501:3,424,112...3,821,727
Ensembl chrNW_004955501:3,423,977...3,821,890 		JBrowse link
G Ephb2 EPH receptor B2 acts_upstream_of_or_within
involved_in 		ISO (PMID:17310244), (PMID:17686994)
(PMID:11585923), (PMID:21029865) 		MGI
ARUK-UCL		 PMID:11585923 PMID:17310244 PMID:17686994 PMID:21029865 NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445 		JBrowse link
G Ephb3 EPH receptor B3 involved_in ISO (PMID:15536074), (PMID:8397371) UniProt PMID:8397371 PMID:15536074 NCBI chrNW_004955420:22,900,588...22,919,924
Ensembl chrNW_004955420:22,901,337...22,920,712 		JBrowse link
G Ephb4 EPH receptor B4 involved_in ISO (PMID:12734395)
(PMID:10518221) 		UniProt PMID:10518221 PMID:12734395 NCBI chrNW_004955573:132,328...150,879
Ensembl chrNW_004955573:132,328...152,595 		JBrowse link
G Git1 GIT ArfGAP 1 acts_upstream_of_or_within ISO (PMID:17310244) MGI PMID:17310244 NCBI chrNW_004955481:3,671,728...3,681,279
Ensembl chrNW_004955481:3,670,111...3,685,051 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142 		JBrowse link
G Nck1 NCK adaptor protein 1 acts_upstream_of_or_within ISO (PMID:19505147) MGI PMID:19505147 NCBI chrNW_004955501:1,867,956...1,963,091 JBrowse link
G Nck2 NCK adaptor protein 2 acts_upstream_of_or_within ISO (PMID:17310244) MGI PMID:17310244 NCBI chrNW_004955470:10,487,962...10,593,046
Ensembl chrNW_004955470:10,487,481...10,593,046 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISO (PMID:17143272) UniProt PMID:17143272 NCBI chrNW_004955453:3,082,826...3,186,039
Ensembl chrNW_004955453:3,082,628...3,186,039 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISO (PMID:10655584) UniProt PMID:10655584 NCBI chrNW_004955461:14,337,914...14,622,779
Ensembl chrNW_004955461:14,337,914...14,556,931 		JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 involved_in ISO (PMID:10655584) UniProt PMID:10655584 NCBI chrNW_004955482:8,934,734...9,031,230
Ensembl chrNW_004955482:8,934,306...9,035,203 		JBrowse link
G Sipa1l1 signal induced proliferation associated 1 like 1 involved_in ISO (PMID:17785183), (PMID:18094260) UniProt PMID:17785183 PMID:18094260 NCBI chrNW_004955523:3,545,807...3,908,329
Ensembl chrNW_004955523:3,545,708...3,797,572 		JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex acts_upstream_of_or_within ISO (PMID:17686994) MGI PMID:17686994 NCBI chrNW_004955402:14,140,261...14,210,467
Ensembl chrNW_004955402:14,140,261...14,210,467 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 acts_upstream_of_or_within ISO (PMID:14988728) MGI PMID:14988728 NCBI chrNW_004955407:30,804,769...31,178,420
Ensembl chrNW_004955407:30,803,653...30,942,854 		JBrowse link
positive regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:17336907) BHF-UCL PMID:17336907 NCBI chrNW_004955443:18,783,061...19,029,441
Ensembl chrNW_004955443:18,783,061...18,910,228 		JBrowse link
regulation of ephrin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chrNW_004955437:2,916,598...3,070,771
Ensembl chrNW_004955437:2,916,598...3,070,771 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12627
    cellular process 12058
      signal transduction 4088
        cell surface receptor signaling pathway 2228
          enzyme-linked receptor protein signaling pathway 872
            cell surface receptor protein tyrosine kinase signaling pathway 556
              ephrin receptor signaling pathway 34
                negative regulation of ephrin receptor signaling pathway 0
                positive regulation of ephrin receptor signaling pathway 1
                regulation of ephrin receptor signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 12627
    biological regulation 9093
      regulation of biological process 8792
        signaling 4579
          signal transduction 4088
            cell surface receptor signaling pathway 2228
              enzyme-linked receptor protein signaling pathway 872
                cell surface receptor protein tyrosine kinase signaling pathway 556
                  ephrin receptor signaling pathway 34
                    negative regulation of ephrin receptor signaling pathway 0
                    positive regulation of ephrin receptor signaling pathway 1
                    regulation of ephrin receptor signaling pathway + 2
paths to the root