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ONTOLOGY REPORT - ANNOTATIONS


Term:hepatocyte growth factor receptor signaling pathway
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Accession:GO:0048012 term browser browse the term
Definition:The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: HGF receptor signaling pathway;   HGF receptor signalling pathway
 narrow_synonym: Met signaling pathway



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hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
IEA
(PMID:21245381)
GO_REF:0000107
RGD
Ensembl
PMID:21245381 GO_REF:0000107 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Hgf hepatocyte growth factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3054501|PMID:15314156)
(PMID:21245381)
RGD PMID:15314156 PMID:21245381 PMID:21873635 MGI:3054501, RGD:13792537 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Muc20 mucin 20, cell surface associated involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3054501|PMID:15314156)
RGD PMID:15314156 PMID:21873635 MGI:3054501, RGD:13792537 NCBI chr11:67,987,729...68,003,997
Ensembl chr11:67,987,800...68,001,495
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21245381) RGD PMID:21245381 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23908241)
UniProt
RGD
PMID:23908241 GO_REF:0000024 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
negative regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
positive regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esm1 endothelial cell-specific molecule 1 involved_in IBA
ISO
PMID:21873635
(PMID:11590178)
RGD PMID:11590178 PMID:21873635 RGD:13792537 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:18819921) RGD PMID:18819921 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS
(PMID:18819921)
GO_REF:0000024
RGD
UniProt
PMID:18819921 GO_REF:0000024 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    signaling 7439
      signal transduction 6859
        cell surface receptor signaling pathway 2772
          enzyme linked receptor protein signaling pathway 978
            transmembrane receptor protein tyrosine kinase signaling pathway 613
              hepatocyte growth factor receptor signaling pathway 13
                negative regulation of hepatocyte growth factor receptor signaling pathway 1
                positive regulation of hepatocyte growth factor receptor signaling pathway 1
                regulation of hepatocyte growth factor receptor signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 19390
    biological regulation 13476
      regulation of biological process 12735
        regulation of cellular process 12196
          signal transduction 6859
            cell surface receptor signaling pathway 2772
              enzyme linked receptor protein signaling pathway 978
                transmembrane receptor protein tyrosine kinase signaling pathway 613
                  hepatocyte growth factor receptor signaling pathway 13
                    negative regulation of hepatocyte growth factor receptor signaling pathway 1
                    positive regulation of hepatocyte growth factor receptor signaling pathway 1
                    regulation of hepatocyte growth factor receptor signaling pathway + 4
paths to the root