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ONTOLOGY REPORT - ANNOTATIONS


Term:hepatocyte growth factor receptor signaling pathway
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Accession:GO:0048012 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: HGF receptor signaling pathway;   HGF receptor signalling pathway
 narrow_synonym: Met signaling pathway



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hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
IEA
(PMID:21245381)
GO_REF:0000107
RGD
Ensembl
PMID:21245381 GO_REF:0000107 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Hgf hepatocyte growth factor involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21245381)
(MGI:3054501|PMID:15314156)
PMID:21873635
RGD PMID:15314156 PMID:21245381 PMID:21873635 MGI:3054501, RGD:13792537 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:3054501|PMID:15314156) RGD PMID:15314156 MGI:3054501 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Muc20 mucin 20, cell surface associated involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3054501|PMID:15314156)
RGD PMID:15314156 PMID:21873635 MGI:3054501, RGD:13792537 NCBI chr11:67,987,729...68,003,997
Ensembl chr11:67,987,800...68,001,495
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21245381) RGD PMID:21245381 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO
IEA
(PMID:25198505)
GO_REF:0000107
RGD
Ensembl
PMID:25198505 GO_REF:0000107 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23908241)
UniProt
RGD
PMID:23908241 GO_REF:0000024 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
negative regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
positive regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esm1 endothelial cell-specific molecule 1 involved_in IBA
ISO
PMID:21873635
(PMID:11590178)
RGD PMID:11590178 PMID:21873635 RGD:13792537 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
regulation of hepatocyte growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:18819921) RGD PMID:18819921 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS
(PMID:18819921)
GO_REF:0000024
RGD
UniProt
PMID:18819921 GO_REF:0000024 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    signaling 7640
      signal transduction 7117
        cell surface receptor signaling pathway 2859
          enzyme-linked receptor protein signaling pathway 1041
            transmembrane receptor protein tyrosine kinase signaling pathway 655
              hepatocyte growth factor receptor signaling pathway 13
                negative regulation of hepatocyte growth factor receptor signaling pathway 1
                positive regulation of hepatocyte growth factor receptor signaling pathway 1
                regulation of hepatocyte growth factor receptor signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 19874
    biological regulation 13526
      regulation of biological process 13079
        regulation of cellular process 12402
          signal transduction 7117
            cell surface receptor signaling pathway 2859
              enzyme-linked receptor protein signaling pathway 1041
                transmembrane receptor protein tyrosine kinase signaling pathway 655
                  hepatocyte growth factor receptor signaling pathway 13
                    negative regulation of hepatocyte growth factor receptor signaling pathway 1
                    positive regulation of hepatocyte growth factor receptor signaling pathway 1
                    regulation of hepatocyte growth factor receptor signaling pathway + 4
paths to the root