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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet-derived growth factor receptor signaling pathway
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Accession:GO:0048008 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PDGF receptor signaling pathway;   PDGF receptor signalling pathway;   PDGFR signaling pathway


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platelet-derived growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO
IEA		 (PMID:18827006), (PMID:20417104)
GO_REF:0000107		 RGD
Ensembl		 PMID:18827006 PMID:20417104 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:99511 (PMID:18827006) RGD PMID:18827006 NCBI chr13:71,223,902...71,319,770
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Arid5b AT-rich interaction domain 5B acts_upstream_of_or_within ISO MGI:3526852 (PMID:17143286) RGD PMID:17143286 NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,307,731...20,487,433 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:9083073)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:9083073 GO_REF:0000024 GO_REF:0000107 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase IDA RGD PMID:11560856 RGD:1600511 NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Cdh11 cadherin 11 acts_upstream_of_or_within ISO MGI:3526861 (PMID:17143286) RGD PMID:17143286 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 acts_upstream_of_or_within ISO
IEA		 (PMID:26437238)
GO_REF:0000107		 RGD
Ensembl		 PMID:26437238 GO_REF:0000107 NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:3526868 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:7623846)		 UniProt
Ensembl
RGD		 PMID:7623846 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:103,520,493...103,821,451 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within ISO MGI:1926435 (PMID:10779359) RGD PMID:10779359 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 involved_in ISO
IEA		 (PMID:17563371)
GO_REF:0000107		 RGD
Ensembl		 PMID:17563371 GO_REF:0000107 NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Itgb3 integrin subunit beta 3 acts_upstream_of_or_within ISO
IEA		 MGI:2175913 (PMID:22984613)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984613 GO_REF:0000107 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jak2 Janus kinase 2 IMP PDGF-induced pancreatic stellate cell proliferation RGD PMID:15948243 RGD:1600095 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir875 microRNA 875 involved_in ISO (PMID:32188878) RGD PMID:32188878 NCBI chr 7:66,861,955...66,862,027
Ensembl chr 7:66,861,955...66,862,027 		JBrowse link
G Myo1e myosin IE acts_upstream_of_or_within ISO MGI:3526864 (PMID:17143286) RGD PMID:17143286 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISO (PMID:23554459) RGD PMID:23554459 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21245381) RGD PMID:21245381 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISS
IBA
NAS
ISO		 GO_REF:0000024
GO_REF:0000033
PMID:7679113
(PMID:2439522), (PMID:2536956), (PMID:2836953)		 UniProt
GO_Central
RGD		 PMID:2439522 PMID:2536956 PMID:2836953 PMID:7679113 GO_REF:0000024 GO_REF:0000033, RGD:151356637 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IMP
IEA
ISO
IBA
NAS		 GO_REF:0000107
(PMID:16477012), (PMID:16530387), (PMID:19088079), (PMID:21245381), (PMID:23554459), (PMID:2439522), (PMID:2536956), (PMID:2836953)
GO_REF:0000033
PMID:7679113		 Ensembl
RGD
GO_Central		 PMID:2439522 PMID:2536956 PMID:2836953 PMID:16477012 PMID:16530387 More... GO_REF:0000033 GO_REF:0000107, RGD:2292197, RGD:151356637 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfc platelet derived growth factor C involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10806482)
(PMID:15372073)
GO_REF:0000033		 RGD
GO_Central		 PMID:10806482 PMID:15372073 GO_REF:0000033 NCBI chr 2:168,613,409...168,791,575
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdgfd platelet derived growth factor D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:10806482), (PMID:2536956)
GO_REF:0000107
GO_REF:0000002
MGI:1926728 (PMID:17143286)
GO_REF:0000024		 RGD
Ensembl
InterPro
UniProt		 PMID:2536956 PMID:10806482 PMID:17143286 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2135508 (PMID:17143286), (PMID:26437238)
GO_REF:0000002
GO_REF:0000107
(PMID:1314164), (PMID:16477012), (PMID:2536956)		 RGD
InterPro
Ensembl		 PMID:1314164 PMID:2536956 PMID:16477012 PMID:17143286 PMID:26437238 GO_REF:0000002 GO_REF:0000107 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Plat plasminogen activator, tissue type involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1857288 (PMID:15372073)		 GO_Central
Ensembl
RGD		 PMID:15372073 GO_REF:0000033 GO_REF:0000107 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 acts_upstream_of_or_within ISO
IEA		 MGI:3526857 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156 		JBrowse link
G Pten phosphatase and tensin homolog IDA RGD PMID:14718524 RGD:1358422 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO
IEA		 MGI:87860 (PMID:18827006)
GO_REF:0000107		 RGD
Ensembl		 PMID:18827006 GO_REF:0000107 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA		 (PMID:21091576)
GO_REF:0000107		 RGD
Ensembl		 PMID:21091576 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:2445403 (PMID:12466202)
GO_REF:0000107		 RGD
Ensembl		 PMID:12466202 GO_REF:0000107 NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in IDA PMID:19878719 UniProt PMID:19878719 RGD:8553779 NCBI chr17:9,254,112...9,268,233
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Schip1 schwannomin interacting protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:3526869 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3526851 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr20:29,590,652...29,637,064
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO
IEA		 (PMID:23651497)
GO_REF:0000107		 RGD
Ensembl		 PMID:23651497 GO_REF:0000107 NCBI chr19:51,072,209...51,155,639
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEP PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Ston1 stonin 1 acts_upstream_of_or_within ISO
IEA		 MGI:5788726 (PMID:26437238)
GO_REF:0000107		 RGD
Ensembl		 PMID:26437238 GO_REF:0000107 NCBI chr 6:11,596,726...11,646,098
Ensembl chr 6:5,843,185...5,892,449 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase acts_upstream_of_or_within ISO
IEA		 MGI:3526866 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Txnip thioredoxin interacting protein acts_upstream_of_or_within ISO
IEA		 MGI:3526865 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Zfand5 zinc finger AN1-type containing 5 acts_upstream_of_or_within ISO
IEA		 MGI:3526860 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 1:218,765,735...218,780,391
Ensembl chr 1:218,766,614...218,775,843 		JBrowse link
G Zfp950 zinc finger protein 950 acts_upstream_of_or_within ISO
IEA		 MGI:3526859 (PMID:17143286)
GO_REF:0000107		 RGD
Ensembl		 PMID:17143286 GO_REF:0000107 NCBI chr 1:260,248,231...260,265,211
Ensembl chr 1:260,236,599...260,265,254 		JBrowse link
negative regulation of platelet-derived growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19460854)
(PMID:12070119)		 UniProt
Ensembl
RGD		 PMID:12070119 PMID:19460854 GO_REF:0000024 GO_REF:0000107 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Apod apolipoprotein D involved_in ISO
ISS		 (PMID:14551159)
GO_REF:0000024		 RGD
UniProt		 PMID:14551159 GO_REF:0000024 NCBI chr11:82,936,216...82,957,264
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA		 (PMID:18977327)
GO_REF:0000107		 RGD
Ensembl		 PMID:18977327 GO_REF:0000107 NCBI chr10:106,237,988...106,256,174
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Ndrg4 NDRG family member 4 involved_in ISO
IEA		 (PMID:12755708)
GO_REF:0000107		 RGD
Ensembl		 PMID:12755708 GO_REF:0000107 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18190691)		 UniProt
RGD		 PMID:18190691 GO_REF:0000024 NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Ptgir prostaglandin I2 receptor involved_in ISO
IEA		 (PMID:20622039)
GO_REF:0000107		 RGD
Ensembl		 PMID:20622039 GO_REF:0000107 NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA		 (PMID:14709717)
GO_REF:0000107
(PMID:12833140)		 RGD
Ensembl		 PMID:12833140 PMID:14709717 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:12239163)
GO_REF:0000107		 RGD
Ensembl		 PMID:12239163 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
negative regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:19460854)		 UniProt
RGD		 PMID:19460854 GO_REF:0000024 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Phf14 PHD finger protein 14 acts_upstream_of_or_within ISO
IEA		 MGI:5426539 (PMID:22730381)
GO_REF:0000107		 RGD
Ensembl		 PMID:22730381 GO_REF:0000107 NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
negative regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glrx glutaredoxin IMP RGD PMID:16893901 RGD:9686048 NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Lrp1 LDL receptor related protein 1 involved_in ISO (PMID:19742316) RGD PMID:19742316 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Myocd myocardin involved_in ISO (PMID:23825366) RGD PMID:23825366 NCBI chr10:50,332,356...50,426,819
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:14966296)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:14966296 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA		 (PMID:2554309)
(PMID:20110689)
GO_REF:0000107		 RGD
Ensembl		 PMID:2554309 PMID:20110689 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO
IEA		 (PMID:24520051)
GO_REF:0000107		 RGD
Ensembl		 PMID:24520051 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24520051) RGD PMID:24520051 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within
involved_in		 IMP
IEA
IBA
ISO		 PMID:18586678
GO_REF:0000107
GO_REF:0000033
MGI:3610732 (PMID:18586678)		 Ensembl
GO_Central
RGD		 PMID:18586678 PMID:18586678 GO_REF:0000033 GO_REF:0000107, RGD:14390060 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
IEA		 (PMID:2554309), (PMID:26599395)
GO_REF:0000107
GO_REF:0000108		 RGD
Ensembl
GOC		 PMID:2554309 PMID:26599395 GO_REF:0000107 GO_REF:0000108 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA		 (PMID:14966296)
GO_REF:0000107		 RGD
Ensembl		 PMID:14966296 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA		 (PMID:17470632)
GO_REF:0000107		 RGD
Ensembl		 PMID:17470632 GO_REF:0000107 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
IEA		 (PMID:17470632)
GO_REF:0000107		 RGD
Ensembl		 PMID:17470632 GO_REF:0000107 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:17470632)
GO_REF:0000107		 RGD
Ensembl		 PMID:17470632 GO_REF:0000107 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISS
ISO		 GO_REF:0000024
(PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19019919)		 UniProt
Ensembl
RGD		 PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
positive regulation of platelet-derived growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor involved_in ISO
IEA		 (PMID:17991872)
GO_REF:0000107		 RGD
Ensembl		 PMID:17991872 GO_REF:0000107 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F7 coagulation factor VII involved_in ISO
IEA		 (PMID:17991872)
GO_REF:0000107		 RGD
Ensembl		 PMID:17991872 GO_REF:0000107 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:16477012) RGD PMID:16477012 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO
IEA		 (PMID:16477012)
GO_REF:0000107		 RGD
Ensembl		 PMID:16477012 GO_REF:0000107 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Mir296 microRNA 296 involved_in ISO (PMID:18977327) RGD PMID:18977327 NCBI chr 3:183,470,069...183,470,146
Ensembl chr 3:163,051,838...163,051,915 		JBrowse link
G Npr2 natriuretic peptide receptor 2 IMP RGD PMID:26410366 RGD:11528696 NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:57,883,171...57,901,580 		JBrowse link
G Nrp1 neuropilin 1 IMP RGD PMID:26410366 RGD:11528696 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
positive regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1 huntingtin interacting protein 1 involved_in ISO
IBA		 (PMID:14732715)
GO_REF:0000033		 RGD
GO_Central		 PMID:14732715 GO_REF:0000033 NCBI chr12:26,769,868...26,904,367
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IBA
IEA		 (PMID:14732715)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:14732715 GO_REF:0000033 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23651497) RGD PMID:23651497 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
regulation of platelet-derived growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO
IEA		 MGI:2384087 (PMID:16344272)
GO_REF:0000107		 RGD
Ensembl		 PMID:16344272 GO_REF:0000107 NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO
IEA		 MGI:97531 (PMID:24023893)
GO_REF:0000107		 RGD
Ensembl		 PMID:24023893 GO_REF:0000107 NCBI chr 2:194,635,686...194,705,014
Ensembl chr 2:191,949,819...192,012,579 		JBrowse link
regulation of platelet-derived growth factor receptor-alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene involved_in ISO
IEA		 (PMID:29237719)
GO_REF:0000107		 RGD
Ensembl		 PMID:29237719 GO_REF:0000107 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cblb Cbl proto-oncogene B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:29237719)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29237719 GO_REF:0000024 GO_REF:0000107 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ift20 intraflagellar transport 20 involved_in ISO
IEA		 (PMID:29237719)
GO_REF:0000107		 RGD
Ensembl		 PMID:29237719 GO_REF:0000107 NCBI chr10:63,930,629...63,936,174
Ensembl chr10:63,432,633...63,438,124 		JBrowse link
regulation of platelet-derived growth factor receptor-beta signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase acts_upstream_of_or_within ISO
IEA		 MGI:2657016 (PMID:21665949)
GO_REF:0000107		 RGD
Ensembl		 PMID:21665949 GO_REF:0000107 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        cell surface receptor signaling pathway 2907
          enzyme-linked receptor protein signaling pathway 1067
            cell surface receptor protein tyrosine kinase signaling pathway 675
              platelet-derived growth factor receptor signaling pathway 70
                VEGF-activated platelet-derived growth factor receptor signaling pathway + 3
                negative regulation of platelet-derived growth factor receptor signaling pathway + 14
                platelet-derived growth factor receptor-alpha signaling pathway + 6
                platelet-derived growth factor receptor-beta signaling pathway + 14
                positive regulation of platelet-derived growth factor receptor signaling pathway + 10
                regulation of platelet-derived growth factor receptor signaling pathway + 30
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          signal transduction 7301
            cell surface receptor signaling pathway 2907
              enzyme-linked receptor protein signaling pathway 1067
                cell surface receptor protein tyrosine kinase signaling pathway 675
                  platelet-derived growth factor receptor signaling pathway 70
                    VEGF-activated platelet-derived growth factor receptor signaling pathway + 3
                    negative regulation of platelet-derived growth factor receptor signaling pathway + 14
                    platelet-derived growth factor receptor-alpha signaling pathway + 6
                    platelet-derived growth factor receptor-beta signaling pathway + 14
                    positive regulation of platelet-derived growth factor receptor signaling pathway + 10
                    regulation of platelet-derived growth factor receptor signaling pathway + 30
paths to the root