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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of peptide antigen
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Accession:GO:0048002 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
Synonyms:exact_synonym: antigen presentation, peptide antigen;   peptide antigen processing and presentation

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antigen processing and presentation of peptide antigen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsl cathepsin L involved_in ISO (MGI:2655909|PMID:9545226), (MGI:3655445|PMID:12021314) UniProt PMID:9545226 PMID:12021314 MGI:2655909 MGI:3655445 NCBI chrNW_004936680:3,047,355...3,050,640 JBrowse link
G Ctss cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:963,176...991,732
Ensembl chrNW_004936580:963,153...991,442 		JBrowse link
G LOC101968486 HLA class II histocompatibility antigen, DQ alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:373,464...378,784 JBrowse link
G LOC101968779 HLA class II histocompatibility antigen, DQ beta 1 chain-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:361,446...368,507
Ensembl chrNW_004936727:361,398...368,532 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3758128|PMID:17620357) MGI
Ensembl		 PMID:17620357 GO_REF:0000107 MGI:3758128 NCBI chrNW_004936569:888,309...895,991
Ensembl chrNW_004936569:887,742...895,977 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778 		JBrowse link
G Ide insulin degrading enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:2,230,477...2,318,562
Ensembl chrNW_004936601:2,230,283...2,318,752 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,899,514...25,907,690
Ensembl chrNW_004936476:25,899,339...25,907,695 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:1758495 MGI
Ensembl
InterPro		 PMID:1758495 GO_REF:0000002 GO_REF:0000107 RGD:1299069 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
G Tapbp TAP binding protein involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936476:25,554,186...25,566,634
Ensembl chrNW_004936476:25,554,403...25,564,330 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:50291|PMID:1538753) MGI
Ensembl		 PMID:1538753 GO_REF:0000107 MGI:50291 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:50291|PMID:1538753) MGI
Ensembl		 PMID:1538753 GO_REF:0000107 MGI:50291 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968
Ensembl chrNW_004936727:540,217...545,036 		JBrowse link
antigen processing and presentation of exogenous peptide antigen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpeg1 macrophage expressed 1 involved_in ISO (MGI:7539255|PMID:35471730) UniProt PMID:35471730 MGI:7539255 NCBI chrNW_004936581:3,428,515...3,436,877
Ensembl chrNW_004936581:3,421,256...3,431,706 		JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:2664488|PMID:11911824) MGI PMID:11911824 MGI:2664488 NCBI chrNW_004936903:514,278...517,975
Ensembl chrNW_004936903:514,761...517,948 		JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2664488|PMID:11911824) MGI
Ensembl		 PMID:11911824 GO_REF:0000107 MGI:2664488 NCBI chrNW_004936580:115,552...144,970
Ensembl chrNW_004936580:115,450...145,785 		JBrowse link
G Ifi30 IFI30 lysosomal thiol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:3,003,366...3,007,003
Ensembl chrNW_004936596:3,002,809...3,007,383 		JBrowse link
G LOC101965910 C-type lectin domain family 4 member A involved_in ISO (PMID:20530286) UniProt PMID:20530286 NCBI chrNW_004936892:454,036...467,957 JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 acts_upstream_of_or_within ISO (MGI:3692789|PMID:17010536) MGI PMID:17010536 MGI:3692789 NCBI chrNW_004936506:7,673,640...7,720,214
Ensembl chrNW_004936506:7,670,630...7,717,157 		JBrowse link
G Mpeg1 macrophage expressed 1 involved_in ISO (MGI:7493537|PMID:37347855) UniProt PMID:37347855 MGI:7493537 NCBI chrNW_004936581:3,428,515...3,436,877
Ensembl chrNW_004936581:3,421,256...3,431,706 		JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tapbp TAP binding protein acts_upstream_of_or_within
involved_in		 ISO (MGI:1289739|PMID:9716645) MGI
UniProt		 PMID:9716645 MGI:1289739 NCBI chrNW_004936476:25,554,186...25,566,634
Ensembl chrNW_004936476:25,554,403...25,564,330 		JBrowse link
antigen processing and presentation of exogenous peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:52620|PMID:7679955), (MGI:79110|PMID:8598040) MGI
Ensembl		 PMID:7679955 PMID:8598040 GO_REF:0000107 MGI:52620 MGI:79110 NCBI chrNW_004936504:4,522,576...4,532,289
Ensembl chrNW_004936504:4,522,751...4,531,750 		JBrowse link
G Ctse cathepsin E involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:6,485,783...6,498,805
Ensembl chrNW_004936557:6,485,755...6,498,833 		JBrowse link
G Ctss cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:963,176...991,732
Ensembl chrNW_004936580:963,153...991,442 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (MGI:2687086|PMID:14643301) MGI PMID:14643301 MGI:2687086 NCBI chrNW_004936903:514,278...517,975
Ensembl chrNW_004936903:514,761...517,948 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (MGI:2687086|PMID:14643301) MGI PMID:14643301 MGI:2687086 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Ifi30 IFI30 lysosomal thiol reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2153425|PMID:11701933) MGI
Ensembl		 PMID:11701933 GO_REF:0000107 MGI:2153425 NCBI chrNW_004936596:3,003,366...3,007,003
Ensembl chrNW_004936596:3,002,809...3,007,383 		JBrowse link
G Lgmn legumain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936733:772,764...792,792
Ensembl chrNW_004936733:772,708...792,995 		JBrowse link
G LOC101958908 HLA class II histocompatibility antigen, DP alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,743,512...25,750,809
Ensembl chrNW_004936476:25,743,456...25,750,907 		JBrowse link
G LOC101959667 HLA class II histocompatibility antigen, DM beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,846,653...25,852,006
Ensembl chrNW_004936476:25,846,630...25,851,409 		JBrowse link
G LOC101963197 HLA class II histocompatibility antigen, DP beta 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,730,800...25,741,089
Ensembl chrNW_004936476:25,730,596...25,741,145 		JBrowse link
G LOC101963482 HLA class II histocompatibility antigen, DO alpha chain acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2671681|PMID:9492004) MGI
Ensembl		 PMID:9492004 GO_REF:0000107 MGI:2671681 NCBI chrNW_004936476:25,786,322...25,790,881
Ensembl chrNW_004936476:25,787,492...25,790,950 		JBrowse link
G LOC101963772 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (MGI:2153656|PMID:11714799)
(MGI:3033882|PMID:11027433)
(MGI:79111|PMID:8598041)
(MGI:79110|PMID:8598040)		 MGI PMID:8598040 PMID:8598041 PMID:11027433 PMID:11714799 MGI:2153656 MGI:3033882 MGI:79110 MGI:79111 NCBI chrNW_004936476:25,836,163...25,840,191
Ensembl chrNW_004936476:25,836,142...25,840,197 		JBrowse link
G LOC101968486 HLA class II histocompatibility antigen, DQ alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:373,464...378,784 JBrowse link
G LOC101968779 HLA class II histocompatibility antigen, DQ beta 1 chain-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:361,446...368,507
Ensembl chrNW_004936727:361,398...368,532 		JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2153656|PMID:11714799), (MGI:3033882|PMID:11027433) Ensembl
MGI		 PMID:11027433 PMID:11714799 GO_REF:0000107 MGI:2153656 MGI:3033882 NCBI chrNW_004936727:540,225...544,968
Ensembl chrNW_004936727:540,217...545,036 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936950:242,071...323,204
Ensembl chrNW_004936950:242,522...320,078 		JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2677080|PMID:14499111) MGI
Ensembl		 PMID:14499111 GO_REF:0000107 MGI:2677080 NCBI chrNW_004936533:1,857,685...1,874,973
Ensembl chrNW_004936533:1,857,666...1,876,120 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3615690|PMID:16415873) MGI
Ensembl		 PMID:16415873 GO_REF:0000107 MGI:3615690 NCBI chrNW_004936599:2,109,292...2,146,006
Ensembl chrNW_004936599:2,109,292...2,117,143 		JBrowse link
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3611636|PMID:16299293) MGI
Ensembl		 PMID:16299293 GO_REF:0000107 MGI:3611636 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3611636|PMID:16299293) MGI
Ensembl		 PMID:16299293 GO_REF:0000107 MGI:3611636 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb9 ATP binding cassette subfamily B member 9 NOT|involved_in ISO (PMID:17977821) UniProt PMID:17977821 NCBI chrNW_004936558:1,689,832...1,718,306
Ensembl chrNW_004936558:1,689,388...1,718,869 		JBrowse link
G B2m beta-2-microglobulin involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778 		JBrowse link
antigen processing and presentation of peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Marchf1 membrane associated ring-CH-type finger 1 involved_in ISO (PMID:18389477)
(MGI:3703462|PMID:17255932), (MGI:4430994|PMID:19917682)		 UniProt PMID:17255932 PMID:18389477 PMID:19917682 MGI:3703462 MGI:4430994 NCBI chrNW_004936555:1,810,896...2,097,870
Ensembl chrNW_004936555:1,610,268...2,097,985 		JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 involved_in ISO (MGI:3785681|PMID:16785530) UniProt PMID:16785530 MGI:3785681 NCBI chrNW_004936728:27,658...32,174 JBrowse link
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hfe homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,940,079...1,947,574
Ensembl chrNW_004936671:1,940,101...1,947,580 		JBrowse link
negative regulation of antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tapbpl TAP binding protein like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936709:1,304,843...1,313,191
Ensembl chrNW_004936709:1,304,971...1,313,770 		JBrowse link
negative regulation of antigen processing and presentation of peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101961309 HLA class II histocompatibility antigen, DO beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,932,926...25,937,024
Ensembl chrNW_004936476:25,932,968...25,936,593 		JBrowse link
G LOC101963482 HLA class II histocompatibility antigen, DO alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,786,322...25,790,881
Ensembl chrNW_004936476:25,787,492...25,790,950 		JBrowse link
peptide antigen assembly with MHC class I protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calr calreticulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430 		JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:6,809,181...6,834,189
Ensembl chrNW_004936471:6,809,195...6,836,169 		JBrowse link
G Tapbp TAP binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,554,186...25,566,634
Ensembl chrNW_004936476:25,554,403...25,564,330 		JBrowse link
G Tapbpl TAP binding protein like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936709:1,304,843...1,313,191
Ensembl chrNW_004936709:1,304,971...1,313,770 		JBrowse link
peptide antigen assembly with MHC class II protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101959667 HLA class II histocompatibility antigen, DM beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,846,653...25,852,006
Ensembl chrNW_004936476:25,846,630...25,851,409 		JBrowse link
G LOC101963772 HLA class II histocompatibility antigen, DM alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,836,163...25,840,191
Ensembl chrNW_004936476:25,836,142...25,840,197 		JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968
Ensembl chrNW_004936727:540,217...545,036 		JBrowse link
peptide antigen stabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tapbp TAP binding protein involved_in ISO (MGI:3687922|PMID:12594855) UniProt PMID:12594855 MGI:3687922 NCBI chrNW_004936476:25,554,186...25,566,634
Ensembl chrNW_004936476:25,554,403...25,564,330 		JBrowse link
peptide antigen transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap2 transporter 2, ATP binding cassette subfamily B member involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
positive regulation of antigen processing and presentation of peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:1758495 RGD:1299069 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427 		JBrowse link
positive regulation of antigen processing and presentation of peptide antigen via MHC class II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pycard PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:18,659,725...18,665,406
Ensembl chrNW_004936476:18,659,815...18,663,940 		JBrowse link
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