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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleoside triphosphate diphosphatase activity
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Accession:GO:0047429 term browser browse the term
Definition:Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.
Synonyms:related_synonym: nucleoside-triphosphate diphosphohydrolase activity;   nucleoside-triphosphate pyrophosphatase activity
 xref: EC:3.6.1.9;   MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN;   Reactome:R-HSA-9755030 "ITPA dimer dephosphorylates RBV-TP to RBV-MP"

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nucleoside triphosphate diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASMTL acetylserotonin O-methyltransferase like enables IEA InterPro GO_REF:0000002
G DCTPP1 dCTP pyrophosphatase 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 5:27,096,489...27,102,778
Ensembl chr 5:27,096,212...27,102,835 		JBrowse link
G DHX9 DExH-box helicase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr25:46,485,602...46,534,046
Ensembl chr25:46,485,427...46,518,406 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables ISO (PMID:10513816), (PMID:11159191), (PMID:25344812), (PMID:7830796)
(PMID:30356045)		 BHF-UCL
UniProt		 PMID:7830796 PMID:10513816 PMID:11159191 PMID:25344812 PMID:30356045 NCBI chr13:41,670,416...41,755,549 JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables IEA Ensembl GO_REF:0000107 Ensembl chr13:41,681,213...41,755,382 JBrowse link
G ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:41,818,559...41,926,901
Ensembl chr13:41,818,874...41,918,259 		JBrowse link
G ITPA inosine triphosphatase enables IEA InterPro
UniProt
RHEA
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr 2:33,873,231...33,893,329
Ensembl chr 2:33,873,339...33,893,556 		JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:25,966,148...25,974,143
Ensembl chr 3:25,966,876...25,973,647 		JBrowse link
2-hydroxy-ATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
2-hydroxy-dATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:25,966,148...25,974,143
Ensembl chr 3:25,966,876...25,973,647 		JBrowse link
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:25,966,148...25,974,143
Ensembl chr 3:25,966,876...25,973,647 		JBrowse link
ATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
dATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:19,332,014...19,340,538
Ensembl chr28:19,327,393...19,338,665 		JBrowse link
dCTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 enables IEA UniProt
TreeGrafter
Ensembl
RHEA		 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 NCBI chr 5:27,096,489...27,102,778
Ensembl chr 5:27,096,212...27,102,835 		JBrowse link
dITP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPA inosine triphosphatase enables IEA Ensembl
RHEA		 GO_REF:0000107 GO_REF:0000116 NCBI chr 2:33,873,231...33,893,329
Ensembl chr 2:33,873,339...33,893,556 		JBrowse link
G NUDT16 nudix hydrolase 16 enables ISO (PMID:20081199) MGI PMID:20081199 NCBI chr15:58,847,418...58,849,133
Ensembl chr15:58,847,560...58,849,246 		JBrowse link
dUTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase enables ISO
IEA		 RGD
Ensembl
TreeGrafter
UniProt
InterPro
RHEA		 PMID:1315924 PMID:3032103 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:2300191 RGD:2301218 NCBI chr26:34,941,775...34,954,184
Ensembl chr26:34,940,702...34,953,166 		JBrowse link
ITP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPA inosine triphosphatase enables IEA RHEA GO_REF:0000116 NCBI chr 2:33,873,231...33,893,329
Ensembl chr 2:33,873,339...33,893,556 		JBrowse link
XTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPA inosine triphosphatase enables IEA RHEA GO_REF:0000116 NCBI chr 2:33,873,231...33,893,329
Ensembl chr 2:33,873,339...33,893,556 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19851
    catalytic activity 5545
      hydrolase activity 2312
        hydrolase activity, acting on acid anhydrides 667
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 667
            pyrophosphatase activity 661
              nucleoside triphosphate diphosphatase activity 11
                2-hydroxy-ATP hydrolase activity 1
                2-hydroxy-dATP hydrolase activity 1
                8-oxo-(d)RTP hydrolase activity 0
                8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 2
                8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity 2
                ATP diphosphatase activity 1
                GTP diphosphatase activity 0
                ITP diphosphatase activity 1
                UTP diphosphatase activity 0
                XTP diphosphatase activity 1
                dATP diphosphatase activity 1
                dCTP diphosphatase activity 1
                dGTP diphosphatase activity 0
                dITP diphosphatase activity 2
                dTTP diphosphatase activity 0
                dUTP diphosphatase activity 1
paths to the root