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ONTOLOGY REPORT - ANNOTATIONS


Term:nucleoside triphosphate diphosphatase activity
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Accession:GO:0047429 term browser browse the term
Definition:Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.
Synonyms:related_synonym: nucleoside-triphosphate diphosphohydrolase activity;   nucleoside-triphosphate pyrophosphatase activity
 xref: EC:3.6.1.9;   MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN;   Reactome:R-HSA-9755030 "ITPA dimer dephosphorylates RBV-TP to RBV-MP"



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nucleoside triphosphate diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASMTL acetylserotonin O-methyltransferase like enables IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr  X:1,102,094...1,118,791
Ensembl chr  X:1,100,747...1,118,791
JBrowse link
G DCTPP1 dCTP pyrophosphatase 1 enables IEA InterPro GO_REF:0000002 NCBI chr 6:17,679,681...17,683,644
Ensembl chr 6:17,679,722...17,683,570
JBrowse link
G DHX9 DExH-box helicase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:16,233,763...16,292,576
Ensembl chr 7:16,233,814...16,292,618
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables ISO (PMID:10513816), (PMID:11159191), (PMID:25344812), (PMID:7830796)
(PMID:30356045)
UniProt PMID:7830796 PMID:10513816 PMID:11159191 PMID:25344812 PMID:30356045 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718
JBrowse link
G ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables IBA GO_Central GO_REF:0000033 NCBI chr12:97,426...195,939
Ensembl chr12:97,483...182,082
JBrowse link
G ITPA inosine triphosphatase enables IEA
IBA
UniProt
GO_Central
InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr24:18,070,980...18,081,815
Ensembl chr24:18,064,983...18,082,163
JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA Ensembl GO_REF:0000107 NCBI chr22:3,416,702...3,424,607
Ensembl chr22:3,416,578...3,424,409
JBrowse link
2-hydroxy-ATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables ISS
IEA
UniProt
RHEA
GO_REF:0000024 GO_REF:0000116 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
2-hydroxy-dATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables ISS
IEA
UniProt
RHEA
GO_REF:0000024 GO_REF:0000116 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA
ISS
RHEA
UniProt
GO_REF:0000003 GO_REF:0000024 GO_REF:0000116 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr22:3,416,702...3,424,607
Ensembl chr22:3,416,578...3,424,409
JBrowse link
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
G NUDT15 nudix hydrolase 15 enables IEA Ensembl GO_REF:0000107 NCBI chr22:3,416,702...3,424,607
Ensembl chr22:3,416,578...3,424,409
JBrowse link
ATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables ISO (PMID:10373420) UniProt PMID:10373420 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
dATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT1 nudix hydrolase 1 enables IEA UniProt GO_REF:0000003 NCBI chr 6:14,874,459...14,881,517
Ensembl chr 6:14,859,518...14,882,704
JBrowse link
dCTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 enables IEA
IBA
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr 6:17,679,681...17,683,644
Ensembl chr 6:17,679,722...17,683,570
JBrowse link
dITP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPA inosine triphosphatase enables ISO (PMID:20081199) MGI PMID:20081199 NCBI chr24:18,070,980...18,081,815
Ensembl chr24:18,064,983...18,082,163
JBrowse link
G NUDT16 nudix hydrolase 16 enables ISO (PMID:20081199) MGI PMID:20081199 NCBI chr23:28,498,730...28,500,998
Ensembl chr23:28,498,652...28,499,998
JBrowse link
dUTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUT deoxyuridine triphosphatase enables ISO
IBA
IEA
RGD
GO_Central
UniProt
InterPro
PMID:1315924 PMID:3032103 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 RGD:2300191 RGD:2301218 NCBI chr30:14,572,766...14,585,621
Ensembl chr30:14,572,602...14,585,530
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 21952
    catalytic activity 5776
      hydrolase activity 2453
        hydrolase activity, acting on acid anhydrides 737
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 736
            pyrophosphatase activity 728
              nucleoside triphosphate diphosphatase activity 10
                2-hydroxy-ATP hydrolase activity 1
                2-hydroxy-dATP hydrolase activity 1
                8-oxo-(d)RTP hydrolase activity 0
                8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 2
                8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity 2
                ATP diphosphatase activity 1
                GTP diphosphatase activity 0
                ITP diphosphatase activity 0
                UTP diphosphatase activity 0
                XTP diphosphatase activity 0
                dATP diphosphatase activity 1
                dCTP diphosphatase activity 1
                dGTP diphosphatase activity 0
                dITP diphosphatase activity 2
                dTTP diphosphatase activity 0
                dUTP diphosphatase activity 1
paths to the root