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ONTOLOGY REPORT - ANNOTATIONS

Term:nucleoside triphosphate diphosphatase activity
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Accession:GO:0047429 term browser browse the term
Definition:Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.
Synonyms:related_synonym: nucleoside-triphosphate diphosphohydrolase activity;   nucleoside-triphosphate pyrophosphatase activity
 xref: EC:3.6.1.9;   MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN;   Reactome:R-HSA-9755030 "ITPA dimer dephosphorylates RBV-TP to RBV-MP"


show annotations for term's descendants           Sort by:
nucleoside triphosphate diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asmtl acetylserotonin O-methyltransferase-like enables IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr12:21,429,119...21,431,847
Ensembl chr12:16,315,414...16,318,080 		JBrowse link
G Dctpp1 dCTP pyrophosphatase 1 enables ISO
IEA
ISS		 (PMID:24467396)
GO_REF:0000002
(PMID:19220460)
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:19220460 PMID:24467396 GO_REF:0000002 GO_REF:0000024 NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:181,877,437...181,880,839 		JBrowse link
G Dhx9 DExH-box helicase 9 enables ISO
IEA		 (PMID:1537828)
GO_REF:0000107		 RGD
Ensembl		 PMID:1537828 GO_REF:0000107 NCBI chr13:68,152,813...68,189,580
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables ISO
IEA
ISS		 (PMID:10513816), (PMID:11159191), (PMID:25344812), (PMID:7830796)
GO_REF:0000003
GO_REF:0000116
(PMID:30356045)
GO_REF:0000024		 RGD
UniProt
RHEA		 PMID:7830796 PMID:10513816 PMID:11159191 PMID:25344812 PMID:30356045 GO_REF:0000003 GO_REF:0000024 GO_REF:0000116 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables ISO
IEA
IBA
ISS		 (PMID:10513816), (PMID:29717535)
GO_REF:0000116
GO_REF:0000003
(PMID:25692702)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
RHEA
UniProt
GO_Central
Ensembl		 PMID:10513816 PMID:25692702 PMID:29717535 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G ENSRNOG00000064603 enables IEA GO_REF:0000002
GO_REF:0000107		 InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 Ensembl chr16:1,393,358...1,394,501 JBrowse link
G Itpa inosine triphosphatase enables IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000116
GO_REF:0000003
(PMID:1914521), (PMID:7323947)
GO_REF:0000033
GO_REF:0000104		 InterPro
RHEA
UniProt
RGD
GO_Central		 PMID:1914521 PMID:7323947 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000116 NCBI chr 3:138,338,549...138,350,329
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
G Nudt15 nudix hydrolase 15 enables ISO (PMID:26238318) RGD PMID:26238318 NCBI chr15:55,117,312...55,123,983
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
2-hydroxy-ATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt1 nudix hydrolase 1 enables ISO
IEA
ISS		 (PMID:11139615)
GO_REF:0000116
GO_REF:0000024		 RGD
RHEA
UniProt		 PMID:11139615 GO_REF:0000024 GO_REF:0000116 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
2-hydroxy-dATP hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt1 nudix hydrolase 1 enables ISO
ISS
IEA		 (PMID:11139615)
GO_REF:0000024
GO_REF:0000116		 RGD
UniProt
RHEA		 PMID:11139615 GO_REF:0000024 GO_REF:0000116 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt1 nudix hydrolase 1 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000116
GO_REF:0000003
(PMID:10608900), (PMID:11139615), (PMID:22556419)		 UniProt
RHEA
RGD		 PMID:10608900 PMID:11139615 PMID:22556419 GO_REF:0000003 GO_REF:0000024 GO_REF:0000116 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
G Nudt15 nudix hydrolase 15 enables ISO
IBA		 (PMID:22556419)
GO_REF:0000033		 RGD
GO_Central		 PMID:22556419 GO_REF:0000033 NCBI chr15:55,117,312...55,123,983
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt1 nudix hydrolase 1 enables ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000002
(PMID:7592783)
GO_REF:0000033
(PMID:10373420), (PMID:22556419)		 UniProt
InterPro
RGD
GO_Central		 PMID:7592783 PMID:10373420 PMID:22556419 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
G Nudt15 nudix hydrolase 15 enables ISO (PMID:22556419)
(PMID:12767940)		 RGD PMID:12767940 PMID:22556419 NCBI chr15:55,117,312...55,123,983
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
ATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Nudt1 nudix hydrolase 1 enables ISO (PMID:10373420) RGD PMID:10373420 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
dATP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt1 nudix hydrolase 1 enables ISO
IEA		 (PMID:11139615)
GO_REF:0000003		 RGD
UniProt		 PMID:11139615 GO_REF:0000003 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
dCTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dctpp1 dCTP pyrophosphatase 1 enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000003
GO_REF:0000116
GO_REF:0000033
(PMID:24467396)		 UniProt
RHEA
GO_Central
RGD		 PMID:24467396 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:181,877,437...181,880,839 		JBrowse link
G ENSRNOG00000064603 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr16:1,393,358...1,394,501 JBrowse link
dITP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itpa inosine triphosphatase enables ISO
IEA		 MGI:4942407 (PMID:20081199)
GO_REF:0000116		 RGD
RHEA		 PMID:20081199 GO_REF:0000116 NCBI chr 3:138,338,549...138,350,329
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
G Nudt16 nudix hydrolase 16 enables ISO
IEA		 (PMID:20081199)
GO_REF:0000107		 RGD
Ensembl		 PMID:20081199 GO_REF:0000107 NCBI chr 8:114,618,706...114,620,761
Ensembl chr 8:105,739,623...105,741,998 		JBrowse link
dUTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001512.1 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000104
GO_REF:0000002
GO_REF:0000003
GO_REF:0000116		 GO_Central
UniProt
InterPro
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000116 Ensembl chr 1:48,369,044...48,369,595 JBrowse link
G Dut deoxyuridine triphosphatase enables IDA
IEA
IBA
ISO		 GO_REF:0000003
GO_REF:0000002
GO_REF:0000116
GO_REF:0000107
GO_REF:0000033
(PMID:8631816)		 UniProt
InterPro
RHEA
Ensembl
GO_Central
RGD		 PMID:8631816 PMID:3032103 PMID:1315924 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:2300191, RGD:2301218 NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G ENSRNOG00000069939 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000104
GO_REF:0000002		 GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 Ensembl chr13:67,763,505...67,765,634 JBrowse link
GTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
ITP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itpa inosine triphosphatase enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 3:138,338,549...138,350,329
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
UTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
XTP diphosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itpa inosine triphosphatase enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 3:138,338,549...138,350,329
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      hydrolase activity 2621
        hydrolase activity, acting on acid anhydrides 779
          hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 779
            pyrophosphatase activity 772
              nucleoside triphosphate diphosphatase activity 13
                2-hydroxy-ATP hydrolase activity 1
                2-hydroxy-dATP hydrolase activity 1
                8-oxo-(d)RTP hydrolase activity 0
                8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 2
                8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity 2
                ATP diphosphatase activity 3
                GTP diphosphatase activity 2
                ITP diphosphatase activity 1
                UTP diphosphatase activity 2
                XTP diphosphatase activity 1
                dATP diphosphatase activity 1
                dCTP diphosphatase activity 2
                dGTP diphosphatase activity 0
                dITP diphosphatase activity 2
                dTTP diphosphatase activity 0
                dUTP diphosphatase activity 3
paths to the root