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ONTOLOGY REPORT - ANNOTATIONS

Term:betaine-homocysteine S-methyltransferase activity
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Accession:GO:0047150 term browser browse the term
Definition:Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.
Synonyms:related_synonym: betaine-homocysteine methyltransferase activity;   betaine-homocysteine transmethylase activity;   trimethylammonioacetate:L-homocysteine S-methyltransferase activity
 xref: EC:2.1.1.5;   KEGG_REACTION:R02821;   MetaCyc:2.1.1.5-RXN;   RHEA:22336;   reactome:R-HSA-1614654 "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY"

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betaine-homocysteine S-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101971919 S-methylmethionine--homocysteine S-methyltransferase BHMT2 NOT|enables ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chrNW_004936549:6,900,075...6,914,217
Ensembl chrNW_004936549:6,899,948...6,914,263 		JBrowse link
G LOC101972215 betaine--homocysteine S-methyltransferase 1 enables ISO
IEA 		RGD
TreeGrafter
Ensembl		 PMID:12487625 PMID:15845641 GO_REF:0000107 GO_REF:0000118 RGD:1359026 RGD:724611 NCBI chrNW_004936549:6,938,100...6,956,380
Ensembl chrNW_004936549:6,938,092...6,957,363 		JBrowse link
Term paths to the root
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  molecular_function 18191
    catalytic activity 5330
      transferase activity 2130
        transferase activity, transferring one-carbon groups 203
          methyltransferase activity 192
            S-methyltransferase activity 10
              betaine-homocysteine S-methyltransferase activity 2
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