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ONTOLOGY REPORT - ANNOTATIONS

Term:betaine-homocysteine S-methyltransferase activity
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Accession:GO:0047150 term browser browse the term
Definition:Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.
Synonyms:related_synonym: betaine-homocysteine methyltransferase activity;   betaine-homocysteine transmethylase activity;   trimethylammonioacetate:L-homocysteine S-methyltransferase activity
 xref: EC:2.1.1.5;   KEGG_REACTION:R02821;   MetaCyc:2.1.1.5-RXN;   RHEA:22336;   reactome:R-HSA-1614654 "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY"


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betaine-homocysteine S-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase enables ISO
IEA
IDA
IBA 		(PMID:8798461) RGD
Ensembl
RHEA
UniProt
GO_Central		 PMID:8798461 PMID:12487625 PMID:15845641 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 RGD:1359026 RGD:724611 NCBI chr 2:87,911,093...87,935,252
Ensembl chr 2:87,910,603...87,935,252 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 NOT|enables ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chr 2:87,866,631...87,882,623
Ensembl chr 2:87,866,621...87,882,716 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 19431
    catalytic activity 5661
      transferase activity 2331
        transferase activity, transferring one-carbon groups 241
          methyltransferase activity 231
            S-methyltransferase activity 10
              betaine-homocysteine S-methyltransferase activity 2
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