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ONTOLOGY REPORT - ANNOTATIONS

Term:betaine-homocysteine S-methyltransferase activity
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Accession:GO:0047150 term browser browse the term
Definition:Catalysis of the reaction: L-homocysteine + glycine betaine = N,N-dimethylglycine + L-methionine.
Synonyms:related_synonym: betaine-homocysteine methyltransferase activity;   betaine-homocysteine transmethylase activity;   trimethylammonioacetate:L-homocysteine S-methyltransferase activity
 xref: EC:2.1.1.5;   KEGG_REACTION:R02821;   MetaCyc:2.1.1.5-RXN;   RHEA:22336;   reactome:R-HSA-1614654 "BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY"


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betaine-homocysteine S-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase enables IMP
IDA
IEA
ISO
IBA		 GO_REF:0000107
PMID:28288879
(PMID:10529246), (PMID:18230605), (PMID:8798461), (PMID:9681996)
(PMID:8798461)
GO_REF:0000033
(PMID:15217352)
GO_REF:0000116
GO_REF:0000003		 Ensembl
RGD
GO_Central
RHEA
UniProt		 PMID:8798461 PMID:9681996 PMID:10529246 PMID:15217352 PMID:18230605 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:724611, RGD:1359026, RGD:151356626 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 NOT|enables ISO (PMID:18230605) RGD PMID:18230605 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      transferase activity 2476
        transferase activity, transferring one-carbon groups 215
          methyltransferase activity 204
            S-methyltransferase activity 10
              betaine-homocysteine S-methyltransferase activity 2
paths to the root