27-hydroxycholesterol 7-alpha-monooxygenase activity - Ontology Report

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Term:	27-hydroxycholesterol 7-alpha-monooxygenase activity	go back to main search page
Accession:	GO:0047092	browse the term
Definition:	Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.
Synonyms:	exact_synonym:	27-hydroxycholesterol 7a-hydroxylase activity; 27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)
	related_synonym:	27-hydroxycholesterol 7-alpha-hydroxylase activity; 27-hydroxycholesterol 7alpha-hydroxylase activity; 27-hydroxycholesterol 7alpha-monooxygenase activity
	xref:	EC:1.14.14.29; MetaCyc:RXN-7980; RHEA:24308

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Genes (1)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cyp7b1

cytochrome P450 family 7 subfamily B member 1

enables

GO_REF:0000116
GO_REF:0000003

GO_REF:0000003 GO_REF:0000116

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

Term paths to the root

Path 1
Term	Annotations
molecular_function	21010
catalytic activity	6145
oxidoreductase activity	871
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	241
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	44
27-hydroxycholesterol 7-alpha-monooxygenase activity	1

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