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ONTOLOGY REPORT - ANNOTATIONS

Term:androsterone dehydrogenase activity
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Accession:GO:0047023 term browser browse the term
Definition:Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
Synonyms:broad_synonym: 3(17)alpha-hydroxysteroid dehydrogenase activity;   3(or 17)alpha-hydroxysteroid dehydrogenase activity;   3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity
 xref: EC:1.1.1.209;   MetaCyc:1.1.1.209-RXN

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androsterone dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P AKR1C1 aldo-keto reductase family 1, member C1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G R Akr1c1 aldo-keto reductase family 1, member C1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G H AKR1C1 aldo-keto reductase family 1 member C1 enables IEA
IBA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G M Akr1c12 aldo-keto reductase family 1, member C12 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,318,171...4,329,398
Ensembl chr13:4,318,175...4,329,432 		JBrowse link
G M Akr1c13 aldo-keto reductase family 1, member C13 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,241,167...4,255,601
Ensembl chr13:4,241,149...4,255,595 		JBrowse link
G R Akr1c14 aldo-keto reductase family 1, member C14 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G M Akr1c14 aldo-keto reductase family 1, member C14 enables ISO
IDA
IBA		 (PMID:16191478) MGI
GO_Central		 PMID:16191478 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:4,099,015...4,140,569
Ensembl chr13:4,099,011...4,140,688 		JBrowse link
G M Akr1c18 aldo-keto reductase family 1, member C18 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G M Akr1c19 aldo-keto reductase family 1, member C19 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,283,499...4,298,360
Ensembl chr13:4,278,699...4,302,842 		JBrowse link
G P AKR1C2 putative aldo-keto reductase family 1 member C2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:65,630,190...65,642,383
Ensembl chr10:65,617,571...65,643,062 		JBrowse link
G R Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO		 GO_REF:0000107
GO_REF:0000118
(MGI:5426779|PMID:15577209), (MGI:5883408|PMID:20124700)		 Ensembl
TreeGrafter
RGD		 PMID:15577209 PMID:20124700 GO_REF:0000107 GO_REF:0000118 MGI:5426779 MGI:5883408 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G H AKR1C2 aldo-keto reductase family 1 member C2 enables IEA
IBA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
G M Akr1c20 aldo-keto reductase family 1, member C20 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344 		JBrowse link
G M Akr1c21 aldo-keto reductase family 1, member C21 enables IMP
ISO
IDA		 (MGI:5883408|PMID:20124700)
(MGI:5426779|PMID:15577209)		 CAFA
MGI
UniProt		 PMID:15577209 PMID:20124700 GO_REF:0000119 MGI:4834177 MGI:5426779 MGI:5883408 NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540 		JBrowse link
G G AKR1C3 aldo-keto reductase family 1 member C3 enables IEA TreeGrafter GO_REF:0000118 Ensembl chr 9:5,248,610...5,263,474 JBrowse link
G P AKR1C3 aldo-keto reductase family 1 member C3 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:65,650,223...65,679,878
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G D AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) enables ISO (PMID:16983398) UniProt PMID:16983398 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G B AKR1C3 aldo-keto reductase family 1 member C3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G R Akr1c3 aldo-keto reductase family 1, member C3 enables ISO
IBA		 (PMID:16983398)
GO_REF:0000033		 RGD
GO_Central		 PMID:16983398 GO_REF:0000033 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G H AKR1C3 aldo-keto reductase family 1 member C3 enables IDA
IBA
IEA		 (PMID:16983398) UniProt
GO_Central
TreeGrafter		 PMID:16983398 GO_REF:0000033 GO_REF:0000118 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G R AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488 		JBrowse link
G P AKR1C4 aldo-keto reductase family 1 member C4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:65,559,508...65,572,892
Ensembl chr10:65,559,508...65,572,895 		JBrowse link
G B AKR1C4 aldo-keto reductase family 1 member C4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:5,247,368...5,271,554
Ensembl chr10:5,234,188...5,258,201 		JBrowse link
G H AKR1C4 aldo-keto reductase family 1 member C4 enables IDA
IEA
IBA		 (PMID:21851338) UniProt
TreeGrafter
GO_Central		 PMID:21851338 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr10:5,196,837...5,218,949
Ensembl chr10:5,195,462...5,218,949 		JBrowse link
G M Akr1c6 aldo-keto reductase family 1, member C6 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876 		JBrowse link
G M Akr1cl aldo-keto reductase family 1, member C-like enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:65,052,237...65,071,918
Ensembl chr 1:65,051,848...65,071,918 		JBrowse link
G B BLOC1S1 biogenesis of lysosomal organelles complex 1 subunit 1 enables IEA Ensembl GO_REF:0000107 NCBI chr12:33,191,882...33,195,566
Ensembl chr12:33,911,309...33,920,506 		JBrowse link
G N Dhrs9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624787:6,751,787...6,776,181
Ensembl chrNW_004624787:6,758,478...6,776,238 		JBrowse link
G G DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr10:54,611,792...54,641,037
Ensembl chr10:54,614,559...54,641,877 		JBrowse link
G P DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr15:75,507,538...75,533,942
Ensembl chr15:75,507,588...75,534,481 		JBrowse link
G S Dhrs9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:10,465,701...10,487,534
Ensembl chrNW_004936469:10,465,701...10,487,534 		JBrowse link
G D DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr36:13,859,935...13,881,432
Ensembl chr36:13,866,959...13,880,179 		JBrowse link
G B DHRS9 dehydrogenase/reductase 9 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:56,347,489...56,376,463
Ensembl chr2B:173,811,932...173,842,816 		JBrowse link
G C Dhrs9 dehydrogenase/reductase 9 enables ISO (PMID:11294878) UniProt PMID:11294878 NCBI chrNW_004955449:5,360,486...5,380,279
Ensembl chrNW_004955449:5,359,617...5,380,267 		JBrowse link
G R Dhrs9 dehydrogenase/reductase 9 enables ISS
ISO		 GO_REF:0000024
(PMID:11294878)		 UniProt
RGD		 PMID:11294878 GO_REF:0000024 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G M Dhrs9 dehydrogenase/reductase 9 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877 		JBrowse link
G H DHRS9 dehydrogenase/reductase 9 enables IDA
IEA		 (PMID:11294878) UniProt PMID:11294878 GO_REF:0000003 NCBI chr 2:169,067,077...169,096,167
Ensembl chr 2:169,064,789...169,096,167 		JBrowse link
G N Hsd17b6 hydroxysteroid 17-beta dehydrogenase 6 enables ISO PMID:9188497
(MGI:1347372|PMID:10537158)
(PMID:10896656), (PMID:11360992)		 UniProt PMID:9188497 PMID:10537158 PMID:10896656 PMID:11360992 MGI:1347372 RGD:1299376 NCBI chrNW_004624802:11,125,544...11,162,914
Ensembl chrNW_004624802:11,115,928...11,162,174 		JBrowse link
G G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr11:52,710,903...52,736,645
Ensembl chr11:52,710,758...52,736,629 		JBrowse link
G P HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:22,089,496...22,114,319
Ensembl chr 5:22,092,578...22,273,382 		JBrowse link
G D HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr10:948,982...1,016,651
Ensembl chr10:1,000,199...1,016,420 		JBrowse link
G B HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA Ensembl GO_REF:0000107 NCBI chr12:32,117,696...32,155,740
Ensembl chr12:32,371,489...32,408,860 		JBrowse link
G R Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 enables ISO
IDA		 (PMID:10896656), (PMID:11360992)
(MGI:1347372|PMID:10537158)
PMID:9188497		 RGD PMID:10537158 PMID:10896656 PMID:11360992 PMID:9188497 MGI:1347372, RGD:1299376 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G M Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 enables IDA
ISO		 (MGI:1347372|PMID:10537158) UniProt
MGI		 PMID:10537158 GO_REF:0000096 GO_REF:0000119 MGI:1347372 MGI:4417868 MGI:4834177 NCBI chr10:127,826,800...127,843,517
Ensembl chr10:127,826,805...127,843,480 		JBrowse link
G H HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 enables IEA
IDA		 (PMID:10896656), (PMID:11360992) UniProt
Ensembl		 PMID:10896656 PMID:11360992 GO_REF:0000003 GO_REF:0000107 NCBI chr12:56,763,324...56,787,790
Ensembl chr12:56,752,161...56,787,790 		JBrowse link
G P LOC100512656 retinol dehydrogenase 16 enables ISO (PMID:9677409) UniProt PMID:9677409 NCBI chr 5:22,277,006...22,285,534
Ensembl chr 5:22,228,057...22,292,434 		JBrowse link
G B LOC100986729 aldo-keto reductase family 1 member C1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:5,003,610...5,020,648
Ensembl chr10:4,990,110...5,003,538 		JBrowse link
G S LOC101954786 aldo-keto reductase family 1 member C1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936484:9,312,113...9,329,269 JBrowse link
G S LOC101965278 retinol dehydrogenase 16 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:1,195,200...1,200,778
Ensembl chrNW_004936646:1,194,547...1,200,897 		JBrowse link
G S LOC101978171 aldo-keto reductase family 1 member C1-like enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:9,177,027...9,196,278 JBrowse link
G G LOC103237807 aldo-keto reductase family 1 member C1 homolog enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:5,123,814...5,138,355
Ensembl chr 9:5,123,529...5,133,053 		JBrowse link
G G LOC103237814 aldo-keto reductase family 1 member C4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:5,310,190...5,338,574 JBrowse link
G B LOC103783188 aldo-keto reductase family 1 member C2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:5,032,692...5,047,009 JBrowse link
G M Rdh1 retinol dehydrogenase 1 (all trans) enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166 		JBrowse link
G G RDH16 retinol dehydrogenase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr11:52,826,447...52,854,731
Ensembl chr11:52,848,488...52,854,167 		JBrowse link
G D RDH16 retinol dehydrogenase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr10:1,124,322...1,134,138
Ensembl chr10:1,124,320...1,130,453 		JBrowse link
G B RDH16 retinol dehydrogenase 16 enables IEA Ensembl GO_REF:0000107 NCBI chr12:31,958,385...31,966,319
Ensembl chr12:32,212,746...32,219,624 		JBrowse link
G R Rdh16 retinol dehydrogenase 16 enables ISS
ISO		 GO_REF:0000024
(PMID:9677409)		 UniProt
RGD		 PMID:9677409 GO_REF:0000024 NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124 		JBrowse link
G M Rdh16 retinol dehydrogenase 16 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,636,959...127,651,715
Ensembl chr10:127,637,021...127,682,434 		JBrowse link
G H RDH16 retinol dehydrogenase 16 enables IEA
IDA		 (PMID:9677409) UniProt PMID:9677409 GO_REF:0000003 NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374 		JBrowse link
G M Rdh16f2 RDH16 family member 2 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,702,345...127,713,188
Ensembl chr10:127,702,343...127,713,186 		JBrowse link
G M Rdh19 retinol dehydrogenase 19 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,685,797...127,697,045
Ensembl chr10:127,685,797...127,697,045 		JBrowse link
G N Rdh5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:12,293,578...12,299,981
Ensembl chrNW_004624802:12,290,688...12,304,712 		JBrowse link
G G RDH5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr11:51,667,461...51,672,386
Ensembl chr11:51,668,803...51,672,192 		JBrowse link
G P RDH5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:21,166,869...21,170,913
Ensembl chr 5:21,166,510...21,170,897 		JBrowse link
G S Rdh5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:191,136...195,279
Ensembl chrNW_004936646:191,128...199,777 		JBrowse link
G D RDH5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr10:120,386...125,195
Ensembl chr10:120,057...125,197 		JBrowse link
G B RDH5 retinol dehydrogenase 5 enables IEA Ensembl GO_REF:0000107 NCBI chr12:33,186,871...33,191,539
Ensembl chr12:33,911,309...33,920,506 		JBrowse link
G C Rdh5 retinol dehydrogenase 5 enables ISO (PMID:9931293) UniProt PMID:9931293 NCBI chrNW_004955458:3,356,324...3,361,701
Ensembl chrNW_004955458:3,352,012...3,365,080 		JBrowse link
G R Rdh5 retinol dehydrogenase 5 enables ISO (PMID:9931293) RGD PMID:9931293 NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558 		JBrowse link
G M Rdh5 retinol dehydrogenase 5 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:128,749,457...128,755,906
Ensembl chr10:128,749,462...128,758,757 		JBrowse link
G H RDH5 retinol dehydrogenase 5 enables IEA
IDA		 (PMID:9931293) UniProt PMID:9931293 GO_REF:0000003 NCBI chr12:55,720,393...55,724,705
Ensembl chr12:55,720,367...55,724,705 		JBrowse link
G M Rdh7 retinol dehydrogenase 7 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,719,896...127,725,116
Ensembl chr10:127,719,897...127,724,686 		JBrowse link
G M Rdh9 retinol dehydrogenase 9 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:127,612,274...127,628,566
Ensembl chr10:127,612,255...127,628,566 		JBrowse link
androsterone dehydrogenase (A-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H AKR1C2 aldo-keto reductase family 1 member C2 enables IEA UniProt GO_REF:0000003 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
androsterone dehydrogenase (B-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G R Akr1c1 aldo-keto reductase family 1, member C1 enables ISO (PMID:8486699) RGD PMID:8486699 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G H AKR1C1 aldo-keto reductase family 1 member C1 enables IDA (PMID:8486699) UniProt PMID:8486699 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G R Akr1c14 aldo-keto reductase family 1, member C14 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277 		JBrowse link
G M Akr1c14 aldo-keto reductase family 1, member C14 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,099,015...4,140,569
Ensembl chr13:4,099,011...4,140,688 		JBrowse link
G M Akr1c20 aldo-keto reductase family 1, member C20 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344 		JBrowse link
G M Akr1c21 aldo-keto reductase family 1, member C21 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540 		JBrowse link
G M Akr1c6 aldo-keto reductase family 1, member C6 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876 		JBrowse link
G M Akr1cl aldo-keto reductase family 1, member C-like enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:65,052,237...65,071,918
Ensembl chr 1:65,051,848...65,071,918 		JBrowse link
G B LOC100986729 aldo-keto reductase family 1 member C1 enables IEA Ensembl GO_REF:0000107 NCBI chr10:5,003,610...5,020,648
Ensembl chr10:4,990,110...5,003,538 		JBrowse link
G B LOC103783188 aldo-keto reductase family 1 member C2 enables IEA Ensembl GO_REF:0000107 NCBI chr10:5,032,692...5,047,009 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 189944
    catalytic activity 54363
      oxidoreductase activity 7182
        steroid dehydrogenase activity 377
          steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 297
            androsterone dehydrogenase activity 74
              androsterone dehydrogenase (A-specific) activity 1
              androsterone dehydrogenase (B-specific) activity 10
Path 2
Term Annotations click to browse term
  molecular_function 189944
    catalytic activity 54363
      oxidoreductase activity 7182
        oxidoreductase activity, acting on CH-OH group of donors 1388
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1292
            steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 297
              androsterone dehydrogenase activity 74
                androsterone dehydrogenase (A-specific) activity 1
                androsterone dehydrogenase (B-specific) activity 10
paths to the root