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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108



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ketone body catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337) RGD PMID:1979337 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 IEP RGD PMID:5116556 RGD:2326095 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 acts_upstream_of_or_within ISO MGI:4364940 (MGI:4946851|PMID:21209089) RGD PMID:21209089 MGI:4946851 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
JBrowse link
G Oxct2b 3-oxoacid CoA transferase 2B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:135,396,632...135,398,386 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      catabolic process 2535
        cellular catabolic process 2172
          ketone body catabolic process 4
            acetoacetic acid catabolic process 0
            acetone catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular metabolic process 10656
        generation of precursor metabolites and energy 498
          ketone body metabolic process 10
            ketone body catabolic process 4
              acetoacetic acid catabolic process 0
              acetone catabolic process 0
paths to the root