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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108



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ketone body catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:36,525,266...36,545,634
Ensembl chr 9:36,525,261...36,545,633
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:5116556 RGD:2326095 NCBI chr 1:7,600,616...7,612,861
Ensembl chr 1:7,598,735...7,612,811
JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4946851|PMID:21209089) InterPro
MGI
Ensembl
PMID:21209089 GO_REF:0000002 GO_REF:0000107 MGI:4946851 NCBI chr16:26,514,497...26,659,739
Ensembl chr16:26,512,396...26,659,845
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16581
    metabolic process 10424
      catabolic process 2288
        cellular catabolic process 1980
          ketone body catabolic process 3
            acetoacetic acid catabolic process 0
            acetone catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 16581
    cellular process 15867
      cellular metabolic process 9471
        generation of precursor metabolites and energy 421
          ketone body metabolic process 10
            ketone body catabolic process 3
              acetoacetic acid catabolic process 0
              acetone catabolic process 0
paths to the root