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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108



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ketone body catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IMP (PMID:1979337) BHF-UCL PMID:1979337 NCBI chr11:108,116,705...108,148,822
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:5116556 RGD:2326095 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4946851|PMID:21209089) MGI
Ensembl
PMID:21209089 GO_REF:0000107 MGI:4946851 NCBI chr 5:41,730,065...41,870,535
Ensembl chr 5:41,730,065...41,870,425
JBrowse link
G OXCT2 3-oxoacid CoA-transferase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:39,769,523...39,771,348
Ensembl chr 1:39,769,523...39,771,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11870
      catabolic process 2682
        cellular catabolic process 2317
          ketone body catabolic process 4
            acetoacetic acid catabolic process 0
            acetone catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 18539
    cellular process 17460
      cellular metabolic process 10810
        generation of precursor metabolites and energy 534
          ketone body metabolic process 12
            ketone body catabolic process 4
              acetoacetic acid catabolic process 0
              acetone catabolic process 0
paths to the root