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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108


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ketone body catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337) BHF-UCL PMID:1979337 NCBI chrNW_004955412:10,350,088...10,369,806
Ensembl chrNW_004955412:10,349,593...10,369,806
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 ISO RGD PMID:5116556 RGD:2326095 NCBI chrNW_004955439:21,123,886...21,142,562
Ensembl chrNW_004955439:21,122,923...21,142,480
JBrowse link
G Oxct1 3-oxoacid CoA-transferase 1 acts_upstream_of_or_within ISO (MGI:4946851|PMID:21209089) MGI PMID:21209089 MGI:4946851 NCBI chrNW_004955426:25,885,518...25,998,187
Ensembl chrNW_004955426:25,885,518...26,003,743
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11982
    metabolic process 7566
      catabolic process 1697
        cellular catabolic process 1477
          ketone body catabolic process 3
            acetoacetic acid catabolic process 0
            acetone catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 11982
    cellular process 11219
      cellular metabolic process 6951
        generation of precursor metabolites and energy 327
          ketone body metabolic process 9
            ketone body catabolic process 3
              acetoacetic acid catabolic process 0
              acetone catabolic process 0
paths to the root